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What is the effect of Montelukast on the amount of IgE in blood?

I know that it decreases the amount of leucotrienes in blood. I saw a patient with high IgE altough under Montelukast medication. This suggests me that Montelukast does not affect the immunoglobulins, ...
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What is the distribution of agent on plasma proteins in ECF?

I am studying Montelukast here: Montelukast is more than 99% bound to plasma proteins. The steady state volume of distribution of montelukast averages 8 to 11 liters. Studies in rats with ...