Pharmacology is the study of the interactions that occur between a living organism and chemicals that affect normal or abnormal biochemical function

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What is LD50 for 25i (25I-NBOMe)?

Firstly I would like to apologise if this is not correct place to ask this question, as it can be seen more as chemistry and not biology question. I was looking around for data on psychedelic ...
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Can neurotransmitter depletion cause short-term drug tolerance?

I'm curious to know if neurotransmitter degradation factors into drug tolerance and neural conduction and, if so, to what extent. As I recall from textbooks I read as an undergrad, one mechanism of ...
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How does Sodium Valproate cause neural plasticity

I have been reading a fascinating paper: Valproate reopens critical-period learning of absolute pitch 18 individuals were given Sodium Valproate (VPA) for a fortnight during which they trained on a ...
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Mesoporous silica particles as anti cancer drug delivery method

If this question is a little off topic for Biology, I'm sorry. I've recently read a lot about mesoporous silica nanoparticles as a promising drug delivery method. The huge range of customizability of ...
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Classify chemotherapy drugs?

I'm studying a TCGA dataset trying to find correlations between gene expression and clinical data which might shed light on some pathways. One column of the clinical data provides a list of ...
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Does tea have its effect if you have a sleep after drinking it?

If I drink tea, then go to sleep for a while, when I wake up, will the effect of tea still be on me (the refreshing effect)? Does it depend on the duration of sleep?
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Pharmacology Half Life Calculation

I'm really stuck on this question. I'm being asked to find the half life of a drug. The Vd is 50L/kg. The clearance is 0.1 L/hr/kg. The patient weighs 70 kg. Equation is: T1/2 (halflife) = 0.693 * ...