Pharmacology is the study of the interactions that occur between a living organism and chemicals that affect normal or abnormal biochemical function

learn more… | top users | synonyms (1)

11
votes
3answers
209 views

Does current evidence support the use of resveratrol as an anti-ageing drug?

A while back there was a lot of noise about resveratrol, a naturally occurring phenol which was touted as a potential anti-aging drug due to its role in regulating the SIRT 1 gene. A number of studies ...
1
vote
1answer
2k views

How do dopamine agonists like amphetamine/methylphenidate affect acetylcholine signalling?

Do they increase it, or is the effect mostly neutral?
4
votes
0answers
110 views

If D1 receptors stimulate adenylate cyclase (through GPCRs) and D2 receptors inhibit it, then why do mutations in both have similar effects?

D1 and D2 both refer to specific types of dopamine receptors. I'm sure it has something to do with the fact that the D1 receptors are in regions different from D2 receptors. I know that adenylate ...
21
votes
2answers
9k views

If a human takes antibiotics are all bacteria in the body killed?

From my basic understanding, antibiotics kill living things, bacteria for example. Do the antibiotics consumed by a human-being distinguish between what they kill? Or do they just kill every bacteria ...
10
votes
1answer
590 views

Why doesn't a substance like loperamide promote analgesia?

Loperamide is frequently used to slow gastrointestinal motility. It is available over the counter (in the US, I don't know about elsewhere) without any regulations whatsoever, yet it's derived from ...
13
votes
2answers
496 views

Intrinsically disordered proteins as potential drug targets

Intrinsically disordered proteins (IDPs) are a class of proteins that do not adopt a stable secondary or tertiary structure under physiological conditions in vitro, but still have biological ...
16
votes
2answers
368 views

Why would diffusion be faster across a non-specialised tissue?

The standard protocol for a person experiencing chest pains is to chew a 300mg aspirin tablet, the argument being that chewing rather than swallowing the tablet results in the aspirin entering the ...
33
votes
1answer
16k views

Why Does Salt Water Help Sore Throats?

I am having some trouble understanding how salt water, a simple solution, could so effectively remove the pains of a sore throat. I do believe that the answer is closely related to hypo/hyper-tonic ...
10
votes
2answers
37 views

Resources for finding all drugs of a certain class

I may be embarking on a project involving a fairly extensive healthcare records data set, looking for the use of a particular type of drug (for example, "Proton Pump Inhibitors"). But these drugs are ...