The study of the normal function of living organisms and the means by which it is achieved.

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How does glucose delivered intraperitoneal (i.p.) get into the peripheral circulation?

Intraperitoneal delivery of drugs or fluids is something that occurs much more frequently in veterinary medicine than clinical medicine. In veterinary medicine or scientific studies using animals, ...
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1answer
60 views

Possible calculations with temperature, humidity, images and VIS spectrum of a plant in an Integrating sphere

I am currently working on a project which involves growing some plants in a integrating sphere made of foam. I have added temperature, humidity and soil moisture sensors as well as a Spectrometer (350 ...
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1answer
42 views

Do goosebumps always appear in the same spots on the skin?

Often one gets goosebumps when one is cold. I am curious whether the precise location of the goosebumps on, say, one's leg changes from occurrence to occurrence or not? In case if their precise ...
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1answer
4k views

How long can an octopus survive out of the water?

I saw videos of octopuses crawling on the ground and I was wondering how long an octopus can survive when out of the water? Does it depend on either its size (i.e., does a big octopus from deep sea ...
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1answer
31 views

Do pharmacodynamics and pharmacokinetics of the drug in animals are the same as in human?

I'm trying to understand the purpose of different clinical trial phases, and the following question comes into my mind : Do pharmacodynamics and pharmacokinetics of the drug in animals are the ...
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1answer
40 views

Why does ESR have to be waited for one hour?

It is said that the length of the column of clear plasma in a narrow tube left by erythrocytes which gradually sediments after one hour is the measure of ESR(erythrocyte sedimentation rate). Its ...
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2answers
4k views

Why does an electrical shock freeze up muscles?

Why is it when someone comes into contact with an electrical supply that their body freezes up and is unable to move away from the electrical source? Can someone explain this through a physiological ...
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20 views

How does excess excretion of NaCl affect Glomerular Filtration Rate and afferent arteriole size?

A toxic drug blocks NaCl resorption channels in the proximal convoluted tubule. What would happen to the Glomerular Filtration Rate (GFR) and afferent arteriole size? If a lot of NaCl is being ...
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39 views

Are cold-blooded animals more energy efficient than warm-blooded animals? [duplicate]

When cold-blooded animals extract energy from glucose, do they do so in a more efficient manner than warm-blooded animals? If they aren't producing heat as a by-product, that would suggest that ...
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2answers
3k views

Why does a blood test show ethanol when no alcohol was consumed?

Why would ethanol show up in a blood test if a person had not been drinking alcohol in many years. What are other reasons for showing ethanol?
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1answer
866 views

Can an organism exist as a single cell but come together as multi-cellular during certain times?

I am trying to remember a particular segment from a BBC special, in which there was single cellular species. However, at certain times all the individual cells came together to form a structure, not ...
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2answers
1k views

How does Bernoulli’s Principle apply to the cardiovascular system?

Below are graphs which illustrate the cross-sectional area, velocity, and fluid pressure through each vascular segment of the cardiovascular system. It makes sense that velocity and cross-sectional ...
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2answers
153 views

What is the effect of persistent hypothermia on cardiac performance?

I define persistent hypothermia in this thread about the mechanisms of persistent hypothermia. The Graph of Katzung et al. in Pharmacology about Heart Failure: I am thinking which parts here are ...
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31 views

How hydrophilic is human mucus?

I am interested in the stability of virus particles in human mucus, and how this may bias the evolution of surface amino acids in respiratory viruses. For instance if the mucus environment were more ...
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2answers
161 views

Do people with gout live longer?

Antioxidants reduce damage to tissue (by scavenging the free radicals) and thus may reduce ageing.It is known that Uric acid is a very good antioxidant. People with gout have excess accumulation of ...
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1answer
4k views

How does a pine cone open?

When a pine cone is wet, it remains closed. However, when it's dry it opens again. From the perspective of physics or biomechanics, what is the mechanism that allows a pine cone to open and close as ...
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1answer
93 views

Are the cells (structures) of deep sea fish different? And can they survive in shallow water?

In the deep oceans the pressure is enormous. But still there are fish living. But are the cells of them different from fish who just live at the surface of waters? For example, are the cells smaller ...
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1answer
97 views

What causes swelling after impact?

Why does the head swell after getting hit by something hard? What is the liquid that forms after impact?
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0answers
18 views

Glycoprotein hormones metabolism

Why do the carbohydrate groups in glycoprotein hormones decrease the rate of metabolism? And increase the half-life?
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2answers
32 views

How does hypocalcaemia have an effect on the excitability of cell [closed]

Hypocalcemia increases sodium influx by leak channels. Why does this elevate the resting membrane potential and increase excitability?
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1answer
59 views

Does food continue to stay sequential once it is inside my body?

I may be very off on many scientific details here, but I'm always all ears. As far as I understand, any food that is eaten goes to the stomach, gets broke down even further into smaller food ...
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0answers
66 views

Can one eye affect the other eye's low-light adaption?

This previous question addresses how long eyes need to adapt to darkness and reach full contrast. My question is how does one eye affect the "transition" and/or efficacy of this "night vision" of the ...
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2answers
355 views

How efficient is the human body at metabolizing food?

My friend and I were having a discussion over how "efficient" human digestion is. If a human ate a 1000 calorie hamburger, how many of those calories (how much energy) does the body process into ...
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3answers
2k views

Why does the face turn pale in dangerous situations?

I know what the effects are of a dangerous situation on the brain, i.e., an activation of the hypothalamic-pituitary-adrenal (HPA) axis which eventually results in an increased heart rate and elevated ...
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0answers
24 views

Determination of Ageing by ECG inclusions/exclusions?

I am studying ageing and considering ECG signal because of its high sensitivity in theory (escardio). Some factors Sensitivity Gender Medical treatment ... Benchmark: RTG dental + wrist ...
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1answer
295 views

What is the maximum altitude where humans can survive?

What is the highest altitude that a human can survive without being pressurized? Let's assume that oxygen and heat/insulation are not the limiting factors? Why I asked.
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1answer
77 views

Is blood pressure in the aorta and brachial artery the same or different?

Does the blood pressure at the root of aorta equal the blood pressure in the brachial artery? I've heard it does, but it doesn't quite seem to make sense as I'd think the blood pressure would be ...
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1answer
62 views

Does our nose detect only if there is change in odor?

If I enter a room with certain odor, I can sense the odor. However, if I stay there for some time I cannot sense it anymore. A new entrant to the room can still smell it or I have to leave the room ...
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1answer
163 views

How does sepsis affect heart function?

I have intuition that sepsis with infection can cause: spastic functioning of heart during systole heart working spontaneously in snatches during systole atrial fibrillation first contraction of ...
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3answers
2k views

Why Doesn’t Hypercalcemia Cause Muscle Spasms?

If you have more calcium in the cell, wouldn’t more attach to troponin and initiate muscle contraction? Why does hypercalcemia cause muscle weakness instead of spasms?
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1answer
119 views

When was the last common ancestor of pig and human?

Some religions regard pigs as unclean on the grounds that pig flesh is closest in composition to human flesh. I don't believe this for one instant, but it got me thinking, just how close is pig and ...
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1answer
148 views

How do cellular waste products enter arterial blood?

I recently learned that blood in renal arteries contains waste materials, which is filtered via nephrons in the kidneys. My question is, how are these waste materials getting into the arterial ...
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1answer
5k views

How do inward rectifier potassium channels work in the heart?

Apparently in cardiomyocytes, there is an inward rectifying potassium channel that operates during phase 4 of the cardiomyocyte action potential. I have heard that despite this potassium channel ...
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1answer
386 views

How is ammonia removed from the colon?

“Lactulose is also used to reduce the amount of ammonia in the blood of patients with liver disease. It works by drawing ammonia from the blood into the colon where it is removed from the body.” ...
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3answers
12k views

Why do men have a higher hematocrit (red blood cell count) than women?

The hematocrit, also known as packed cell volume (PCV) or erythrocyte volume fraction (EVF), is the volume percentage (%) of red blood cells in blood. It is normally 45% for men and 40% for women. ...
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1answer
264 views

Is there nutrient absorption in the large intestine of hindgut fermenters?

In hindgut fermenters, plants are digested in the caecum by microbes. I want to know whether hindgut fermenters can absorb the nutrients obtained from the digestion in the large intestine because the ...
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1answer
79 views

What is the effect of exendin on beta-cells?

Do you know if exendin, an analog of GLP-1 (glucagon like peptide-1), can be toxic for beta-cells? For example, what is the effect on INS1 or Min6 cells at a certain concentration or after 90 mins of ...
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1answer
81 views

Which is more susceptible to dehydration — extracellular and intracellular fluid?

I want to ask in human body, there is intracellular and extracellular fluid that makes up the total body water of our body, which is drained first when we do activities? extra or intra? if I want to ...
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1answer
159 views

Why are some human injections intraperitoneal?

In humans, what benefit do intraperitoneal (IP) injections(old/cheap rabies vaccines, or cancer related injections) offer versus traditional intramuscular injections? For example, where I live, the ...
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3answers
2k views

Why do we exhale after we hold our breath?

I tested this out with my friends, and I find that after they hold their breath and can't hold it anymore, they exhale air, instead of inhaling air. Interestingly, they all try to inhale in as much ...
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1answer
56 views

How body loses more fat in CO2 form than in sweating form? [closed]

Yesterday, I saw TV Game Show. There is question like this: Body loses more fat in which form? It gave 4 options: 1) CO2 2) sweating 3) xxx 4) xyz sorry i didn't remember 3 & 4 options. ...
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2answers
372 views

How does the microbial environment in your gut initiate?

Clearly, a zygote does not harbor any microbes. As it develops, and the alimentary canal tissue is differentiated, I logically assume that there is still no microbial activity in the fetus's gut. I'm ...
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2answers
419 views

Where do the bacteria within the vagina originate from?

I understand that it's feasible the bacteria within the gastrointestinal tract originate from the food we eat and air we breath, but where does this population of microbes originate from?
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1answer
749 views

Why does a fetus drinks and urinates into the amniotic fluid?

I was reading this website saying that fetuses urinate into the amniotic fluid. It also mentioned that, because we drink the amniotic fluid, we’ve been drinking our urine for months. However, why do ...
3
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1answer
238 views

Are the byproducts of mammalian digestion simply depleted versions of the food or liquid consumed?

When mammals consume food and digest it or drink fluids that are then filtered by their kidneys, are the waste products generated simply depleted versions of what they consumed? Are there other ...
6
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1answer
63 views

How can hyperthyroidism induce osteoporosis?

It says in my physiology notes that hyperthyroidism can cause osteoporosis. I've been trying to figure out how this could be possible for a little more than an hour now. Every article that I look at ...
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3answers
8k views

Why is defibrillation in asystole (“flat line”) useless?

In most popular medical dramas, when a patient has a cardiac arrest and "flatlines" the doctors many times use a defibrillator to "shock the heart back into rhythm'. I know that actually, the proper ...
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1answer
47 views

How much is local blood non-Newtonian in Pathophysiology?

I am studying the Barus effect / Merrington effect / die swell / extrudate swell, which is a characteristic of non-Newtonian viscoelastic liquids (Introduction to the phenomenon in this video) i.e. ...
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1answer
93 views

What is enantiostasis?

I have searched around and read my textbook but I am failing to understand how enantiostasis is different to homeostasis. For reference, Wikipedia definition is as follows: Enantiostasis is the ...
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1answer
131 views

Which organs in the body are responsible for measuring temperature?

As an instrumentation engineer, I have designed temperature control systems capable of measuring and controlling temperature with a precision of 0.001K over a wide temperature range. I have always ...