The study of the normal function of living organisms and the means by which it is achieved.

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2answers
149 views

Why do skin and nail go blue in cyanosis?

I have learned that Cyanosis presents with blue skin and nails. What is the reason for the blue coloration of the skin and nails? Why wont the skin and nails turn another color in the visible spectrum ...
9
votes
1answer
223 views

Why doesn't HDL cause diseases like LDL? [duplicate]

LDL particles pose a risk for cardiovascular disease when they invade the endothelium and become oxidized, since the oxidized forms are more easily retained by the proteoglycans. A complex set of ...
0
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1answer
35 views

How is oxygen and carbon dioxide exchange mediated by hemoglobin? [closed]

Oxygen is transferred by hemoglobin from the lungs to tissues, while carbon dioxide is transferred by hemoglobin from tissues to lungs. How is this regulated bidirectional transfer mediated?
4
votes
2answers
519 views

Why do men have a higher hematocrit (red blood cell count) than women?

The hematocrit, also known as packed cell volume (PCV) or erythrocyte volume fraction (EVF), is the volume percentage (%) of red blood cells in blood. It is normally 45% for men and 40% for women. ...
13
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0answers
2k views

Why do we experience temperatures below 37 degrees Celsius as 'hot'? [duplicate]

We always prefer to be in 20-25° C, although our core temperature is about 37°? Why is our skin temperature lower than our core temperature?
7
votes
1answer
91 views

Can humans live without their right atrium?

The right atrium is one of four chambers (two atria and two ventricles) in the hearts of mammals (including humans) and archosaurs (which include birds and crocodilians). It receives deoxygenated ...
3
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1answer
170 views

Hydrogen Peroxide on Open Wounds

I know that H2O2 is a chemical with high oxidative potential. It can deliver nascent oxygen which can destroy bacteria. I understand that open wounds have cells that are dividing at a fast rate to ...
0
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2answers
67 views

What is the effect of persistent hypothermia on cardiac performance?

I define persistent hypothermia in this thread about the mechanisms of persistent hypothermia. The Graph of Katzung et al. in Pharmacology about Heart Failure: I am thinking which parts here are ...
5
votes
3answers
121 views

Which fruit compounds affect the speed of fructose absorption?

Blood fructose levels are not regulated by insulin in the human body. This means that the body absorbs pure fructose very fast, and it raises the blood fructose levels rapidly. Do fruits/ vegetation ...
5
votes
1answer
103 views

What's the worst that can happen from too much sleep deprivation? Can you die?

It is well known that sleep deprivation causes considerable discomfort in humans (and has even used as a form of torture), but nevertheless there have been people who went through protracted sleep ...
8
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2answers
178 views

Why don't we see turbulence in the aorta even in normal situations?

I read about the Windkessel effect. Then I read about pulse pressure waves getting reflected from the periphery. If the pulse pressure wave is reflected during diastole and at the same time blood is ...
1
vote
1answer
44 views

Double use of ATP in relaxing myosin & active transportation of calcium?

Is the ATP molecule which is bound to the myosin head for relaxation of the muscle (i.e., to break the cross bridge) also utilized for active transport of calcium to the sarcoplasmic reticulum during ...
9
votes
3answers
1k views

Do snakes get dizzy?

I've seen snakes get captured in sacks and I've wondered if the snake would get dizzy if the sack were twirled around. I have not done any tests (and don't plan to) because snakes scare me.
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vote
0answers
25 views

Would blue light be effective to help average people when sunsets come much earlier in the day?

I know people with SAD (Seasonal Affective Disorder) benefit from blue light in the winter as night-time comes much earlier (in the UK, sunset is around 4pm in December, compared to 9pm in June). ...
1
vote
1answer
51 views

What specific sensory nerves act as receptors for “pins and needles” (neuropathy)?

According to this excellent answer, the difference between "pain" and "pins and needles" (neuropathy) is that different receptors (sensory nerves) trigger in reaction to different stimuli. Different ...
6
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2answers
248 views

Why does anxiety cause diarrhea or constipation?

Anxiety sometimes cause diarrhea, sometimes constipation, and sometimes both. It's interesting because it seems their underlying neurophysiology is somehow different. What are underlying physiological ...
0
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0answers
32 views

Maximum heart rate increase/decrease while physically active [duplicate]

I'm a computer scientist and implementing a heart-rate monitor for physical exercise. While I try to improve my code, I stumbled over the question how fast the heart rate can change within a given ...
0
votes
1answer
32 views

Deeper Learning in Physiology? [closed]

I am a Pharmacology and Toxicology major at a large state school. I was only required to take physics I and II. (algebra based) At first I thought that was fine, but I soon began to realize that I ...
9
votes
3answers
245 views

What causes feeling of feet falling asleep to be delayed?

This answer explains the sensation of extremities "falling asleep" as a result of sustained pressure on a nerve. The answer links to an external web page that says that the feeling "quickly goes away ...
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vote
0answers
31 views

How do you accurately measure anguiliform (eel) locomotion?

In one of my courses, we were discussing a paper by Muller and van Leeuwen (2006) which made a lot of comparisons the differences between carangiform (mullet) and anguilliform (eel) locomotion. While ...
2
votes
1answer
50 views

How to manage fat-gluten oxidation in celiac disease?

Assume you have been in non-gluten diet 20 years. You built mass 8 mass with substances containing gluten (endogenous gluten stored in fat). Then, celiac disease is diagnosed. You have been 3 ...
4
votes
1answer
76 views

Does transplanted heart have full sympaticus without medication?

I am reading this and this where I am considering this sentence [N]o baseline parasympathetic innervation [in transplanted heart]. Does this sentence imply that the heart work then in full ...
1
vote
3answers
108 views

Resilience to the neurotoxins of Indian King Cobra

I read on Wikipedia about this: King Cobra - Wikipedia In Thailand, a concoction of alcohol and the ground root of turmeric is ingested, which has been clinically shown to create a strong ...
0
votes
1answer
22 views

Ephedrine or pseudoephedrine indirectly central alpha2 mimetic?

I started to think this problem by first thinking if the alpha2 mimetism is possible in either case. It seems to be indirectly in either one. Ephedrine seems to have more prominent effect in CNS. ...
1
vote
1answer
33 views

Is Norepinephrine beta2 adrenomimetic?

I know that it has alpha1, alpha2 and beta1 effects. It has beta2 receptor where epinephrine can effect. However, to say that it is beta adrenomimetic, I am not sure. That is ligand binding beta2 ...
0
votes
1answer
42 views

How can succinylcholine cause myorelaxation?

I first thought that this is because of prolonged depolarisations. However, I am not sure anymore, because after reading PubChem, the only possible pathways are are Choline agonist. So I would say ...
7
votes
2answers
1k views

Can human organs be transplanted indefinitely?

I watched this movie, where they rented hearts to people for a year. I wonder if it is possible to transplant a heart indefinitely from person to person, or does the heart have a lifetime? So, do ...
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vote
1answer
57 views

Does pupil size affect image focus in persons with no lens?

If an individual has no lens like Claude Monet (who had them removed). They should be able to still focus the images they see in a well light area if they shrink their pupils to a very small size ...
0
votes
1answer
33 views

Does vitamin D form crystals in the blood with calcium and magnesium?

I read on a vitamin-D product (2000NE) that I should not use calcium and magnesium with it, because it can result crystal formation in the blood. I googled, but find anything about this. Is it true? ...
2
votes
2answers
67 views

How does the cell regulate different metabolic pathways?

I heard somewhere that cells use different nucleosides bound to triphosphates e.g. ATP, GTP, CTP and other modified compounds: NADH, NADPH to distinguish between different metabolic pathways and so ...
2
votes
2answers
63 views

Does the cellular response to every receptor work the same way?

I heard somewhere that activating any receptor results in the same intracellular response (signaling) which involves NF-κB. If that is true, I hardly understand how the cells distinguish between ...
6
votes
2answers
308 views

Does muscle get bigger by increase in size of individual cells or increase in number?

Somewhere in the back of my mind, I have the claim that a muscle never increases its amount of cells but, if the muscle gets bigger, it's simply because individual cells get bigger. The book Anatomy ...
3
votes
1answer
74 views

Do human visual functions degenerate due to genetic factors or by external factors?

Does eyesight primarily deteriorate 'naturally' due to genetics (genomic/epigenomic factors), or due to external factors such as normal wear and tear, or disease? By normal wear and tear I include ...
1
vote
1answer
61 views

Why is LH level much higher than FSH level at ovulation?

My teacher showed us an elaborate collection of graphs with one of them showing FSH and LH plasma levels during the menstrual cycle. LH level was almost 3 times higher than FSH level. Why? Does this ...
5
votes
1answer
62 views

Examples of genes involved in plastic responses

Adaptive plasticity involves sensing the environment and responding adaptively to it. Intuitively, I would think that this process may ask for a more or less complex genetic machinery of regulation of ...
5
votes
2answers
125 views

How do diving marine mammals avoid decompression sickness?

How do marine mammals, whose very survival depends on regular diving, manage to avoid decompression sickness or "the bends?" Do they, indeed, avoid it?
5
votes
1answer
65 views

How does anadromous fish physiology “know” to switch from salt to freshwater and back?

What mechanism allows anadromous fish (like salmon) to switch from salt to fresh water and back? How does the fish "know" to switch its physiology and do other fish possess the biochemical machinery ...
3
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0answers
53 views

Does eating antacid (such as Magnesia) before meal have any impact on digestion? [closed]

During an anatomy lecture I heard of the importance of the acidity of gastric acid (e.g., killing microorganisms, dissolving food, being a factor for triggering further processes). If a healthy person ...
0
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2answers
119 views

What is the name of the condition where no pacemaker cells are active in the heart for a short-time?

Assume that the heart is beating, but no pacemaker cells are working for at least 15 seconds. This would be a very long compensatory pause if extrasystole started it. There may be some low frequent ...
0
votes
1answer
55 views

Does repolarization of muscle fibers mean that the muscle bundle is relaxed?

If I flex my bicep and continue to contract it does it mean that the muscle cells are in depolarizing state and not repolarizing?
1
vote
0answers
27 views

Physiology of benign eye twitching?

About four times in my life I have experienced the feeling of my eyelid fluttering for a few minutes by itself, and then it stops. I have talked to other people who have had the same experience so I ...
6
votes
3answers
146 views

Why do I feel funny in my tummy when riding a virtual roller coaster?

I've ridden a virtual roller coaster on an Oculus Rift. I felt tension as I went up to the top, but more interestingly I actually felt my stomach drop when I went down the steep drop on the other ...
3
votes
0answers
59 views

Which organs in the body are responsible for measuring temperature?

As an instrumentation engineer, I have designed temperature control systems capable of measuring and controlling temperature with a precision of 0.001K over a wide temperature range. I have always ...
2
votes
1answer
279 views

What is the difference between rheobase and threshold?

Neuronal tissues can be excited by electrical stimulation. Two commonly encountered characteristics for electrically stimulating nerve cells is the threshold and the rheobase. My question is what the ...
0
votes
1answer
85 views

What is the difference between the basal membrane and the basal lamina?

I'm researching about the basal lamina in lung tissue and I'm not sure if the basal membrane is the same. What is the difference between them?
3
votes
0answers
36 views

How many cells are there in the apical meristematic tissue?

How many cells are there in the apical meristematic tissue? Looking at this picture... , I would tend to think that there are few hundreds cells in the meristem tissue. But I guess this is a ...
1
vote
1answer
147 views

What are the risks of elevating the legs too regularly and when tired?

I started to to think the pathophysiology of elevating legs high next to the wall too often and when you are tired. I think possible manifestations some damage to valves of the veins (No!) because ...
1
vote
1answer
93 views

Is there a known glucosepane cross-link breaker?

I read the following on wikipedia: There is, however, no agent known that can break down the most common AGE, glucosepane, which appears 10 to 1,000 times more common in human tissue than any ...
1
vote
0answers
37 views

Why are there no animals with a length greater than 30-40 meters or with a mass greater than 200 tonnes? [duplicate]

The biggest and heaviest aquatic animal is the blue whale: 30 meters long and a mass of 200 tonnes. The biggest and heaviest terrestrial animal was a Sauropod (plant-eating, long-necked dinosaur): 40 ...
3
votes
1answer
379 views

NADH inhibits gluconeogenesis?

I was told in a physiology lecture that alcohol inhibits gluconeogenesis because 'NADH produced from ethanol catabolism leads to product inhibition'. But is NADH not a reactant coenzyme of ...