The study of the normal function of living organisms and the means by which it is achieved.

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What's the worst that can happen from too much sleep deprivation? Can you die?

It is well known that sleep deprivation causes considerable discomfort in humans (and has even used as a form of torture), but nevertheless there have been people who went through protracted sleep ...
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122 views

Why do small organisms make faster movements than big organisms?

I hesitated to ask this question because it seems so obvious and intuitive. However, I am not able to explain this tendency. Background It seems to me that small organisms make faster movements than ...
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256 views

Where do the 31 spinal nerves start/meet?

Which part of the brain is the first place (from top to bottom) where all 31 pairs of spinal nerves (on each side) meet? Or if they all start at one place - where is that? Nominally, the beginning of ...
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122 views

By what mechanism can hypoglycemia induce fainting?

Hypoglycemia (Low blood sugar) is said to be among the potential causes of human-faintings. I was wondering by which mechanism this happens. Google search results are abundant; there are lists of ...
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185 views

Would my hands sweat this much if I wasn't wearing gloves?

I've wondered about this for a long time, and hopefully someone here has a reasonable answer. I'm a cell and molecular biologist, and much of my time at the bench is spent wearing (usually nitrile) ...
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356 views

Skeletal muscles in clam

Although skeletal muscle fatigues fairly rapidly, clams have a protein called paramyosin that allows them to sustain contractions for up to a month. What might be the role of paramyosin at the ...
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2k views

How much gas is exchanged in one human breath?

When we breathe, our lungs absorb a portion of the oxygen in the air, and replace it with some amount of carbon dioxide and water vapor. Typically, how much $O_2$ (in grams, milliliters, or moles for ...
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165 views

Do dogs have something different about their physiology that allows them to pant without hyperventilating?

I was wondering this as I considered how effective panting would be for humans as a means of cooling.
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134 views

How do diving marine mammals avoid decompression sickness?

How do marine mammals, whose very survival depends on regular diving, manage to avoid decompression sickness or "the bends?" Do they, indeed, avoid it?
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584 views

What metabolic activities are performed by a developing human fetus's liver?

I understand that organ function varies with the stages of development. Does a fetal liver EVER perform lipogenesis, gluconeogenesis, make bile, etc? Or does it only begin performing these actions ...
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271 views

Biological Pathway of Lipid Hypothesis

I've read a lot on both sides of the debate of low carb vs low fat diets trying to make some sense of what is being proposed. The lipid hypothesis runs roughly along the lines that we have lots of ...
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189 views

Is a raised baseline between T and QRS normal in any ECG lead?

Here are excerpts from an unknown ECG lead. I find it weird that the "baseline" changes after the T wave and doesn't return until after the following QRS complex. Is that normal/expected for any lead? ...
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47 views

Components of the concept of Developmental Noise?

Developmental noise is a concept that correspond to the amount of possible phenotypic variance of a given genotype in a given environment. Intrinsic noise (aka Cellular noise) is a component of ...
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196 views

What happens to fecal matter if it's continually re-eaten?

After class today, the topic of eating one's one fecal matter came up. There was a sharp divide as to how people thought the defecations would change. I realize this is a bit of an odd question but ...
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59 views

Is hands-only CPR as effective as traditional CPR?

Is hands-only CPR as effective as traditional CPR ? Wouldn't 30 chest compressions + 2 rescue breaths be more effective if the person doesn't have a pulse AND not breathing? From my understanding ...
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65 views

Examples of genes involved in plastic responses

Adaptive plasticity involves sensing the environment and responding adaptively to it. Intuitively, I would think that this process may ask for a more or less complex genetic machinery of regulation of ...
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118 views

Mechanism of Muscle Growth

According to this video (sorry for the poor reference but it represents my level of understanding in physiology), muscle grow as a consequence of repairing micro-lesions. How are these micro-lesions ...
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91 views

How does a Na+/H+ antiporter drive osmosis in this “osmotic motor”?

This recent paper in Cell describes a cancer cell using osmotic pressure to move in confined spaces. The cell preferentially inserts Na+/H+ antiporters in the leading membrane. I want someone to ...
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92 views

Enlargement of thyroid gland

Why does thyroid gland enlarge both in hypothyroidism and hyperthyroidism? Hypothyroid goitre is due to lack of iodine in diet and hyperthyroid goitre (Exopthalmic goitre, Grave's disease) is due to ...
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132 views

Which fruit compounds affect the speed of fructose absorption?

Blood fructose levels are not regulated by insulin in the human body. This means that the body absorbs pure fructose very fast, and it raises the blood fructose levels rapidly. Do fruits/ vegetation ...
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84 views

How does anadromous fish physiology “know” to switch from salt to freshwater and back?

What mechanism allows anadromous fish (like salmon) to switch from salt to fresh water and back? How does the fish "know" to switch its physiology and do other fish possess the biochemical machinery ...
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111 views

Competition for mates in sea horses

This source here ...research has shown that it is STILL the males that compete for females. says that male sea horses compete for mates but this source here Females exhibit a ...
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148 views

functional hypocholesterolemia due to very high HDL or low LDL?

Nutritional and medical recommendations about cholesterol seem to focus exclusively on hypercholesterolemia, and as such, they provide only a maximum desirable level for LDL and a minimum for HDL. ...
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114 views

Dimensionless number for blood volume

Comments from the question How is the blood volume of a living organism measured without killing it? by @Nico discussed that the time of blood recirculation scales with the size of the organism. I was ...
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The number of nipples (breasts) a species has?

Only mammals have mammaries and mammary glands. What evolutionary factors determines the number of mammaries (nipples/teats/breasts) a species has? Is it always an even number?
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217 views

How does vasoconstriction/vasodilation change blood pressure?

Background: I am coming at this question from an electrical engineering background, and I feel like I am missing certain assumptions that are going into the statement found in my physiology textbook, ...
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229 views

Body size, what are the evolutionary trade-offs?

Background Considering just the "Kingdom Animalia" branch of organisms. It is clear that bigger does not necessarily mean better - there is large variation in body size... From the 94 µm long ...
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Why are (some) cats attracted by bleach?

(Sorry if this question is only partly biological) I have noticed that several cats (including the one that keeps sleeping in my house), are fond of the odor of bleach (eau de Javel) and chlorine. ...
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269 views

How does strength of a pulse related to EKG(ECG)?

There are variabilities in the heart rate as well as strength of heartbeats. I want to know if one can predict which heartbeat will be strong or weak based on the corresponding EKG/ECG signal. I am ...
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90 views

Question about epinephrine

In my class we were told that adrenaline (or epinephrine) causes vasoconstriction. My question was I had always thought that people took this via an EpiPen when they were having an allergic reaction. ...
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177 views

Relationship between nerves and axons

I just wanted to get a realistic viewpoint of our nervous system. I understand arteries and veins, but I wanted to know how similar our nervous system is to that? I understand we have neurons ...
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164 views

Why do skin and nail go blue in cyanosis?

I have learned that Cyanosis presents with blue skin and nails. What is the reason for the blue coloration of the skin and nails? Why wont the skin and nails turn another color in the visible spectrum ...
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How does a pine cone open?

When a pine cone is wet, it remains closed. However, when it's dry it opens again. From the perspective of physics or biomechanics, what is the mechanism that allows a pine cone to open and close as ...
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145 views

What are some examples of scaling laws in biology?

I've seen that metabolic rate scales logarithmically as function of mass for many animals over an extremely large span of parameters. What other scaling laws exist at the individual level?
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Does transplanted heart have full sympaticus without medication?

I am reading this and this where I am considering this sentence [N]o baseline parasympathetic innervation [in transplanted heart]. Does this sentence imply that the heart work then in full ...
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194 views

How does ethanol interact with insulin?

I know that ethanol increases insulin secretion--could someone explain why? All I have found till now is experimental data analyses. I am interested in mechanism of alcohol consumption.
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180 views

Negative feedback in the fructose metabolism in liver

What happens in liver when large amount of fructose is consumed? I vaguely remember my biochemistry lecturer telling us that the enzymes that process fructose in the liver does not have negative ...
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139 views

How do animals handle light refraction in different media?

For a human, when diving underwater, everything is blurry because of the water's different refractive index compared to that of air, which we are accustomed to. How do animals, like turtles, seals or ...
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123 views

What is the physiological difference between cortisone and cortisol?

There is only hydrogen bond different. Cortisol is synthesized by our body, while cortisone is given to the patient. Why you cannot give cortisol directly to the patient? I think the reason is ...
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102 views

Are there any situations in which phenylephrine is preferred to pseudoephedrine?

In the mid 2000s in the US, due to issues of drug enforcement, pseudoephedrine containing medications were brought behind the pharmacy counter and in most cases require ID, and phenylephrine was ...
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134 views

How can we measure cardiac output?

I could find a way which could find it by body oxygen consumption and there is another way to measure it by injecting drugs — measuring cardiac output by the so-called “indicator dilution method,” a ...
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135 views

How efficient is the human body at metabolizing food?

My friend and I were having a discussion over how "efficient" human digestion is. If a human ate a 1000 calorie hamburger, how many of those calories (how much energy) does the body process into ...
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351 views

Extraretinal photoreception in mammals? [duplicate]

A Finnish firm Valkee sells light-ear-plugs against thing such as jetlag. I asked a researcher in Aalto university how do they really work and he responded ...
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244 views

what are the mechanics of sweating?

The causes of sweating aside, i.e. I'm not interested in which and how nerve signals are transmitted to sweat glands. But I would like to read a detailed account on what a sweat gland consists of, ...
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431 views

What causes instinctive behaviour?

Some actions, almost behaviour, exist that are common across a species. For instance, based on personal observation, human babies try to taste anything new they encounter until they are a few score ...
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166 views

Is there a way for a 19th century scientist to prove that the octopus doesn't revive?

Say a sophiscated scientist in the 19th century noted that applying soy sauce on a dead octopus leads to movement of the legs, as a result of the voltage differences resulting from the salt in the soy ...
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169 views

Why mosquito bite is confined to a certain shape?

I think this problem should be asked in a physiology forum rather than biology@ stackex but I'll give it a try. So my question is simple - why a mosquito bite is usually confined to a certain shape ...
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91 views

The mechanism of mechanoreception?

I am interested in knowing the molecular mechanism behind mechanoreception/mechanotransduction (i.e. mechanism behind receptor potential generation on mechanical stimulation). I know that most ...
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539 views

How is membrane capacitance related to the increased speed of saltatory conduction?

Here is the original question which inspired my question. As explained by the answers there, the reason saltatory conduction in myelinated neurons is faster than non-myelinated conduction is because ...
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What are the molecular mechanisms that make the turtle brain more resistant to hypoxia?

I know that turtle brains, particularly those of individual species that hibernate and burrow are particularly resilient to hypoxia and any tissue damage secondary to a hypoxic event. What are the ...