The study of the normal function of living organisms and the means by which it is achieved.

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How does Humira work when injected into patients with rheumatoid arthritis?

OK, I have rheumatoid arthritis and I've been injecting Humira 2 times a month for the last 8 months. As far as I know rheumatoid arthritis is simply an immune system disorder which makes the immune ...
2
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1answer
118 views

Sodium levels and blood pressure

Why does low Na+ levels cause hypotension (low blood pressure). Alternatively, why does excessive intake of Na+ cause hypertension or high blood pressure? From what I understand, there are ...
2
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1answer
94 views

How to manage fat-gluten oxidation in celiac disease?

Assume you have been in non-gluten diet 20 years. You built mass 8 mass with substances containing gluten (endogenous gluten stored in fat). Then, celiac disease is diagnosed. You have been 3 ...
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1answer
118 views

Why the scent of mouth gets dirty after not eating for a long time?

After a long time of hard workout,not eating and nervousness makes your taste and scent of mouth very uncomfortable and bad why this happens and is there any way to prevent it?
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1answer
143 views

Mechanism of Muscle Growth

According to this video (sorry for the poor reference but it represents my level of understanding in physiology), muscle grow as a consequence of repairing micro-lesions. How are these micro-lesions ...
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1answer
38 views

Is Norepinephrine beta2 adrenomimetic?

I know that it has alpha1, alpha2 and beta1 effects. It has beta2 receptor where epinephrine can effect. However, to say that it is beta adrenomimetic, I am not sure. That is ligand binding beta2 ...
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1answer
24 views

Ephedrine or pseudoephedrine indirectly central alpha2 mimetic?

I started to think this problem by first thinking if the alpha2 mimetism is possible in either case. It seems to be indirectly in either one. Ephedrine seems to have more prominent effect in CNS. ...
2
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1answer
537 views

What is the difference between rheobase and threshold?

Neuronal tissues can be excited by electrical stimulation. Two commonly encountered characteristics for electrically stimulating nerve cells is the threshold and the rheobase. My question is what the ...
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2answers
1k views

Can human organs be transplanted indefinitely?

I watched this movie, where they rented hearts to people for a year. I wonder if it is possible to transplant a heart indefinitely from person to person, or does the heart have a lifetime? So, do ...
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2answers
130 views

What are the physiological roles of Hydrogen sulfide?

I am thinking why hydrogen sulfide has its effects in the body. For instance, it is one Salmonella's virulence factor. I am not sure if such a balance equations holds H2O + H2S ←→ ... Actually, I ...
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2answers
716 views

Does muscle get bigger by increase in size of individual cells or increase in number?

Somewhere in the back of my mind, I have the claim that a muscle never increases its amount of cells but, if the muscle gets bigger, it's simply because individual cells get bigger. The book Anatomy ...
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1answer
82 views

Do human visual functions degenerate due to genetic factors or by external factors?

Does eyesight primarily deteriorate 'naturally' due to genetics (genomic/epigenomic factors), or due to external factors such as normal wear and tear, or disease? By normal wear and tear I include ...
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1answer
41 views

Does vitamin D form crystals in the blood with calcium and magnesium?

I read on a vitamin-D product (2000NE) that I should not use calcium and magnesium with it, because it can result crystal formation in the blood. I googled, but find anything about this. Is it true? ...
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2answers
88 views

How does the cell regulate different metabolic pathways?

I heard somewhere that cells use different nucleosides bound to triphosphates e.g. ATP, GTP, CTP and other modified compounds: NADH, NADPH to distinguish between different metabolic pathways and so ...
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1answer
102 views

Why is LH level much higher than FSH level at ovulation?

My teacher showed us an elaborate collection of graphs with one of them showing FSH and LH plasma levels during the menstrual cycle. LH level was almost 3 times higher than FSH level. Why? Does this ...
5
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2answers
169 views

How do diving marine mammals avoid decompression sickness?

How do marine mammals, whose very survival depends on regular diving, manage to avoid decompression sickness or "the bends?" Do they, indeed, avoid it?
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1answer
91 views

What is the mechanism behind ventilatory acclimatization?

In my respiratory physiology lectures, my professor explained that hypoxia-induced hyperventilation occurs in 2 stages when people try to acclimate at high altitudes. My question is about the ...
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2answers
2k views

Ill effects of urea and NH₃ on metabolism

What exactly does urea do that harms our body? Does it interfere with our cellular processes or disturbs the colloidal onchotic pressure of our blood? I have heard that NH3 damages the brain. What ...
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0answers
66 views

Does eating antacid (such as Magnesia) before meal have any impact on digestion? [closed]

During an anatomy lecture I heard of the importance of the acidity of gastric acid (e.g., killing microorganisms, dissolving food, being a factor for triggering further processes). If a healthy person ...
7
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3answers
211 views

Why do I feel funny in my tummy when riding a virtual roller coaster?

I've ridden a virtual roller coaster on an Oculus Rift. I felt tension as I went up to the top, but more interestingly I actually felt my stomach drop when I went down the steep drop on the other ...
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3answers
1k views

How are our senses dimmed during sleep?

Our senses are not as sensitive during sleep compared to wake. There is an arousal threshold during sleep that only when it is overcome will it wake a person up. My question is how is this arousal ...
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0answers
30 views

Physiology of benign eye twitching?

About four times in my life I have experienced the feeling of my eyelid fluttering for a few minutes by itself, and then it stops. I have talked to other people who have had the same experience so I ...
6
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2answers
22k views

What could cause hairs to gray at the tips but not the roots?

I have noticed that some of my sporadic gray hairs are gray at the tip side but oddly, not near the roots. Some are even only gray in the middle. I find all of this very counter intuitive, and I ...
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1answer
287 views

What is the difference between the basal membrane and the basal lamina?

I'm researching about the basal lamina in lung tissue and I'm not sure if the basal membrane is the same. What is the difference between them?
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0answers
68 views

Which organs in the body are responsible for measuring temperature?

As an instrumentation engineer, I have designed temperature control systems capable of measuring and controlling temperature with a precision of 0.001K over a wide temperature range. I have always ...
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1answer
895 views

NADH inhibits gluconeogenesis?

I was told in a physiology lecture that alcohol inhibits gluconeogenesis because 'NADH produced from ethanol catabolism leads to product inhibition'. But is NADH not a reactant coenzyme of ...
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0answers
40 views

Why are there no animals with a length greater than 30-40 meters or with a mass greater than 200 tonnes? [duplicate]

The biggest and heaviest aquatic animal is the blue whale: 30 meters long and a mass of 200 tonnes. The biggest and heaviest terrestrial animal was a Sauropod (plant-eating, long-necked dinosaur): 40 ...
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1answer
1k views

How long can a bee surive in a jar?

So, some people and I encountered an adventure game where you have a bee in a jar and need to move it from place to place before it suffocates, and someone tried to find out how long a bee would ...
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1answer
125 views

cellular respiration

What are the effects of addition of these chemicals to actively respiring cells ? Which of them would lead to INHIBITION of aerobic respiration ? Would cytochromes be actually taken up by cells ? ...
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3answers
298 views

What difference does it make in the organism's physiology/metabolism whether oxygen binds reversibly or not?

A follow-up to How does hemoglobin-free blood transport oxygen? I'm unsure about the use of physiology/metabolism in the title there. The question in mind is whether this reversible binding makes an ...
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2answers
2k views

How do insects breathe?

Do ants even breathe? If they don't, how do they stay alive? On what resources do they depend upon to stay alive? How are they different form mammals?
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1answer
225 views

Why can CO₂ be transported dissolved in plasma?

Is it because CO2 is more soluble in water or has it got to do with the alkaline pH of plasma ?I here mean only aqueous CO2 transport from body cells to lungs.
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3answers
153 views

What gaseous substances do humans emit?

Other than CO₂ and Methane what other gases do humans produce or emit? For example, does skin decomposition, or aerobic respiration emit any special gases that people don't normally realize or know ...
5
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2answers
159 views

Why do small organisms make faster movements than big organisms?

I hesitated to ask this question because it seems so obvious and intuitive. However, I am not able to explain this tendency. Background It seems to me that small organisms make faster movements than ...
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1answer
51 views

All or nothing phenomena

We know that an action potential is produced by an active cell membrane when the stimulus reaches a certain threshold. When it does, an action potential fires, and when it doesn't, nothing happens. ...
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2answers
1k views

How do we know the presence of light when our eyes are closed?

Last night I laid on my bed and tried to go to sleep with the light off. I closed my eyes (but hadn't gone to sleep). My younger brother touched the wireless mouse (which had laser) for the laptop. ...
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1answer
135 views

What is the mechanism responsible for the periodicity of hiccups?

Hiccups (singultus) are caused by involuntary spasm of the intercostal muscles and diaphragm, producing a sudden inspiration with associated glottic closure. It seems the neurobiology of the reflex ...
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1answer
56 views

Normal position of Electrical axis only in the III lead?

I found this sentence in my notes which is not exact enough: Electrical axes Excitatory processes have definite direction and magnitude and could therefore be represented as vectors. At ...
0
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2answers
166 views

Can you disconnect sensation from the brain without destroying muscle functions?

I want to know if it would be possible for a surgeon to "shut off" a person's senses without causing paralysis of any kind. The person would have to maintain their ability to speak and move, but not ...
3
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1answer
60 views

Mechanisms of bone growth

The length of a bone is caused by growth of hyaline cartilage which is then replaced by bone tissue. How do cells know whether they should grow the hyaline cartilage? What are the key molecules that ...
2
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0answers
56 views

Biology Experiment Data (Hodgkin-Huxley)

I'm doing research into the Hodgkin-Huxley Model from an electronics/mathematics perspective and I'm looking to find actual numerical results from experiments on squid axons. I want to compare the ...
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1answer
55 views

Normal Frequencies in Heart

I am trying to visualise possible ranges of frequencies from different structures of heart: different valves and their possible frequencies heart sounds I - IV and their normal frequencties what can ...
3
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1answer
380 views

What are the highest and lowest possible pH, paCO2 and HCO3 in the blood of living human?

What are the highest and lowest possible values of pH, $paCO_2$, and $HCO_3$ in the (arterial or venous) blood of a living human being?
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2answers
1k views

Do women have testosterone?

In a documentary on fitness I saw it was stated that women can't get big like men because of their low concentration of testosterone. If it is true that women have testosterone, where is it made? Why ...
2
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1answer
52 views

Kinesiology Tape Benefits

Recently, kinesiology tape has become popular, especially in CrossFit. I have also noted its' use in the NFL, and I want to say Tennis as well. What beneficial effects does this tape offer our bodies ...
7
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1answer
15k views

What is the normal duration of human sexual intercourse?

Wikipedia is saying: Men's typical ejaculatory latency is approximately 4–8 minutes How the researchers measured this? How did they know if the test subjects weren't suffering from premature ...
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1answer
33 views

What triggers the release of gonadotrophin-releasing hormone with the onset of puberty?

I am interested to know the process of development of puberty. During puberty, when boys/girls reache 12-14 (puberty) years of their age, their hypothalamus releases gonadotropin releasing hormone ...
5
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2answers
314 views

Where do the 31 spinal nerves start/meet?

Which part of the brain is the first place (from top to bottom) where all 31 pairs of spinal nerves (on each side) meet? Or if they all start at one place - where is that? Nominally, the beginning of ...
28
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3answers
5k views

What actually happens when my leg 'falls asleep'?

Most people have experienced the temporary loss of feeling and tingling in their leg resulting from sitting in an abnormal position for a short while. Usually you get a loss of feeling in your leg ...
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1answer
153 views

brain activity responsible for imagination

Which part of brain is responsible for advance or unseen imagination For example:ones brain can make a situation in mind which is impossible to happen ...which part of brain is hyper active?