The study of the normal function of living organisms and the means by which it is achieved.

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1answer
158 views

Why do people in the scientific community use terminology such as renal, hepatic, cardiac instead of kidney, liver and heart? [closed]

Are there differences between renal, hepatic, cardiac and kidney, liver and heart? Is the "jargon" used more commonly because of tradition, or is there some definitive biological basis to it?
3
votes
2answers
647 views

When glucose production is low, the brain begins using ketoacids as energy… how does that work?

Can someone very generally describe how the brain consumes ketoacids/ketone bodies when blood glucose has been completely depleted?
1
vote
1answer
342 views

What is the so called “hepatic glucose production”

I came across this term in my readings but I do not understand how this works. Can someone direct me to some reference as to what this "hepatic" glucose production is all about?
1
vote
1answer
137 views

Given an EC50 value, how do I reproduce the sigmoidal curve from which this was calculated?

All-trans retinoic acid (atRA) is a potent ligand for a nuclear receptor called retinoic acid receptor alpha (RARa). The concentration of atRA at which RARa is half maximal is 19nM. The dose-response ...
3
votes
1answer
78 views

Liver - Regeneration in Cirrhosis

Liver is the most resilient of the human organ (on par with or next to skin). A very interesting experiment on liver regeneration is here. Even if two-thirds of the liver is removed, the remaining ...
5
votes
1answer
185 views

Case study and speculations on the brain of Edward Mordake

I am very interested in the case of the man named Edward Mordake who lived in the 19th century. In particular, he had two faces. If you have not heard of this man, please, search this up as there are ...
3
votes
0answers
30 views

Blood as newtonian flow and Poiseuille law [closed]

For a prep exam: A healtly pacient has a carotid with the following characteristics: intern ratio: ๐‘…= 2.8 mm, ๐‘ƒ2 = 89 ๐‘š๐‘š๐ป๐‘”, ๐‘ƒ1 = 90 ๐‘š๐‘š๐ป๐‘”, ๐œ‡blood = 3.5 cp, ๐ฟ=10.0 cm. Using the ...
2
votes
1answer
313 views

How to define drug-resistant or -sensitive cell line when knowing the IC50 values?

I have got the IC50 data for a drug on different cell lines. How to define if the cell line is sensitive or resistant towards this drug? Could anyone tell me how to define this?
3
votes
1answer
111 views

How is circadian rhythm of gastric acid secretion regulated?

Gastric acid secretion shows a circadian rhythm where acid production in the morning is minimal and it reaches a maximum towards the evening. How is this process regulated?
3
votes
3answers
685 views

What is the difference between meristem and bud?

Keep reading both terms quite frequently while studying plant physiology. I did some research trying to establish their differences and I learnt that meristems are undifferentiated cells that can ...
2
votes
2answers
405 views

Why can newborns swim?

I am wondering for someone to discuss the phenomena that newborn babies (humans) are able to submerge underwater up until a few months where that ability is lost again? What is the explanation for ...
4
votes
1answer
129 views

What is the impact of stress on the human body?

Can stress trigger any changes in the human body? I'd like to know more about things less commonly known than, for example: sweating and tiredness. What are the long term risks of chronic stress? Do ...
10
votes
2answers
641 views

Should we induce fever to assist healing?

I am currently reading "The Fundamentals of Anatomy Physiology" 10th edition, and have found it an incredibly interesting book. I have just been reading about the lymphatic system, and the various ...
0
votes
1answer
165 views

Similarity between a heart attack and a spasm

When someone is having a heart attack, could it be considered , in some situations, a spasm? Below, I have written how I believe the process may work. The heart is basically a muscle working ...
6
votes
5answers
329 views

Is the amount of blood that flows through every vein and artery per minute really a constant?

I was listening lectures from Mark Saltzman via Open Yale Courses. Now, if I did not understand him wrong, he said that the amount of blood that travels through every vein and artery in our bodies per ...
5
votes
1answer
181 views

Is hands-only CPR as effective as traditional CPR?

Is hands-only CPR as effective as traditional CPR ? Wouldn't 30 chest compressions + 2 rescue breaths be more effective if the person doesn't have a pulse AND not breathing? From my understanding (...
6
votes
2answers
5k views

What physiological processes within a muscle cause the latent period in a muscle fiber?

This is a lab question I cant find the answer in the lab manual or in the text book. What physiological processes in a muscle cause the latent period in a muscle fiber? Please help. Edit: The latent ...
2
votes
1answer
94 views

Is Norway spruce (Picea abies (L.) Karst.) isohydric or anisohydric species?

Question from a thesis defense list ask me this. But I can't find the exact answer on the internet or in books. In my thesis, I described isohydric plants, for example maize, lupin, pea, poplar. This ...
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vote
0answers
26 views

how food moves in horizontal coils of small intestines [duplicate]

This is a very very basic question, and I am looking at it more from point of view of physics. The small intestine is a highly coiled structure, which means it has horizontal coils as well. I can ...
2
votes
1answer
60 views

Detailed mechanism of the cause of diabetes mellitus type 1?

I have read in some texts that diabetes mellitus type 1 is caused by degeneration of beta cells due to our body's own immune reaction.Is it true? Can you explain further how are such types of immune ...
1
vote
1answer
229 views

How does ANF increase GFR?

ANF as we know reduce the Na+ uptake and K+ removal in the distal tubules and it also functions as a Vasodialator (?) But again it says that ANF increases the Glomerular filtrate ? But if it is acting ...
5
votes
1answer
141 views

Normal ECG/EKG Measurement?

I'm getting started using ECG using a 3 lead system by iWorx. I have place the leads on my two wrists and the ground on my ankle and have recorded some data into the provided LabScribe 3 software ...
1
vote
3answers
217 views

Does the necessary Carbon Dioxide need to be in the atmosphere for mammals?

In the answers to this question, we've learnt that carbon dioxide is necessary for mammalian life, but is it necessary in the atmosphere/to breathe it in? Or does the act of respiration give a ...
9
votes
2answers
150 views

Why can good music raise goosebumps?

Listening to really good music right now, I was wondering why it raises goosebumps. Is there any physiological reason for this reaction to specific wavelengths or something? EDIT: Due sometimes ...
6
votes
1answer
541 views

Relationship between nerves and axons

I just wanted to get a realistic viewpoint of our nervous system. I understand arteries and veins, but I wanted to know how similar our nervous system is to that? I understand we have neurons (...
3
votes
0answers
87 views

What's Incomplete atrioventricular heart block (AV)? [closed]

This is unclear for me and I can not understand differences between complete and incomplete atrioventricular heart block.also I want an electrocardiograph of incomplete atrioventricular heart block.
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votes
2answers
8k views

Why do we urinate more when we are nervous?

This question is a result of my personal experience... But I guess that is common for many of us. My school timing is 8:00 am to 1:30 pm (usually). During normal school days I typically urinate one ...
2
votes
1answer
165 views

Biphasic T wave caused by digitalis toxicity

Digitalis is a drug that can be used during coronary insufficiency to increase the strength of cardiac muscle contraction. But when overdosages of digitalis are given, depolarization duration in ...
2
votes
1answer
2k views

What happens to our umbilical cord internally as we age?

I was always curious as to if or how much of the internal structure or workings of the umbilical cord are still in existence as we age. What happens to it over time? The wikipedia article naval ...
1
vote
1answer
142 views

Why is pericardium muscle repolarizated earlier than endocardium? [closed]

I was reading about heat muscle contraction and I read: The endocardium depolarization happens earlier than pericardium , but pericarduim repolarization happens earlier, therefore the T wave in ...
6
votes
1answer
176 views

Do people with congenital analgesia feel cold?

There are a few diseases that cause an insensitivity to pain. This question asks about the relationship between the cold and pain, which got me thinking: Is shivering a response driven by the ...
2
votes
1answer
88 views

Why is the resting potential of a neuron so close to the equilibrium potential of Kโบ?

I know this has something to do with the K+ leak channel. I just don't understand how. I know that 3 Na+ are pumped out for every 2 K+ pumped in. This makes the cell interior net negative. I know ...
5
votes
3answers
1k views

How does vasoconstriction/vasodilation change blood pressure?

Background: I am coming at this question from an electrical engineering background, and I feel like I am missing certain assumptions that are going into the statement found in my physiology textbook, "...
3
votes
1answer
466 views

Whatโ€™s the reason for isovolumic contraction and isovolumic relaxation?

During cardiac cycle, there are two periods in which the heart volume doesnโ€™t change, but there is a change in tension/pressure. It takes about 0.25-0.35 second to achieve this change. I searched in ...
3
votes
2answers
170 views

Why can't we defibrillate the heart within 1 minute after ventricular fibrillation by electroshock?

We mostly can defibrillate the heart before 1 min of ventricular fibrillation by electroshock.Then we often can't do defibrillate it with electroshock. What's the reason and What's the best way to ...
3
votes
1answer
59 views

Why do the size of the phase 1 notch vary among cardiac cells?

The size of the phase 1 notch varies among cardiac cells. It is prominent in myocytes in the epicardial and midmyocardial regions of the left ventricular wall and in ventricular Purkinje fibers. ...
4
votes
1answer
264 views

How can we measure cardiac output?

I could find a way which could find it by body oxygen consumption and there is another way to measure it by injecting drugs โ€” measuring cardiac output by the so-called โ€œindicator dilution method,โ€ a ...
5
votes
2answers
602 views

Why do skin and nail go blue in cyanosis?

I have learned that Cyanosis presents with blue skin and nails. What is the reason for the blue coloration of the skin and nails? Why wont the skin and nails turn another color in the visible spectrum ...
12
votes
1answer
746 views

Why doesn't HDL cause diseases like LDL? [duplicate]

LDL particles pose a risk for cardiovascular disease when they invade the endothelium and become oxidized, since the oxidized forms are more easily retained by the proteoglycans. A complex set of ...
1
vote
1answer
64 views

How is oxygen and carbon dioxide exchange mediated by hemoglobin? [closed]

Oxygen is transferred by hemoglobin from the lungs to tissues, while carbon dioxide is transferred by hemoglobin from tissues to lungs. How is this regulated bidirectional transfer mediated?
7
votes
4answers
14k views

Why do men have a higher hematocrit (red blood cell count) than women?

The hematocrit, also known as packed cell volume (PCV) or erythrocyte volume fraction (EVF), is the volume percentage (%) of red blood cells in blood. It is normally 45% for men and 40% for women. so,...
13
votes
0answers
2k views

Why do we experience temperatures below 37 degrees Celsius as 'hot'? [duplicate]

We always prefer to be in 20-25ยฐ C, although our core temperature is about 37ยฐ? Why is our skin temperature lower than our core temperature?
7
votes
1answer
364 views

Can humans live without their right atrium?

The right atrium is one of four chambers (two atria and two ventricles) in the hearts of mammals (including humans) and archosaurs (which include birds and crocodilians). It receives deoxygenated ...
3
votes
1answer
402 views

Hydrogen Peroxide on Open Wounds

I know that H2O2 is a chemical with high oxidative potential. It can deliver nascent oxygen which can destroy bacteria. I understand that open wounds have cells that are dividing at a fast rate to ...
2
votes
2answers
160 views

What is the effect of persistent hypothermia on cardiac performance?

I define persistent hypothermia in this thread about the mechanisms of persistent hypothermia. The Graph of Katzung et al. in Pharmacology about Heart Failure: I am thinking which parts here are ...
5
votes
3answers
237 views

Which fruit compounds affect the speed of fructose absorption?

Blood fructose levels are not regulated by insulin in the human body. This means that the body absorbs pure fructose very fast, and it raises the blood fructose levels rapidly. Do fruits/ vegetation ...
5
votes
1answer
243 views

What's the worst that can happen from too much sleep deprivation? Can you die?

It is well known that sleep deprivation causes considerable discomfort in humans (and has even used as a form of torture), but nevertheless there have been people who went through protracted sleep ...
8
votes
2answers
295 views

Why don't we see turbulence in the aorta even in normal situations?

I read about the Windkessel effect. Then I read about pulse pressure waves getting reflected from the periphery. If the pulse pressure wave is reflected during diastole and at the same time blood is ...
1
vote
1answer
55 views

Double use of ATP in relaxing myosin & active transportation of calcium?

Is the ATP molecule which is bound to the myosin head for relaxation of the muscle (i.e., to break the cross bridge) also utilized for active transport of calcium to the sarcoplasmic reticulum during ...
10
votes
3answers
1k views

Do snakes get dizzy?

I've seen snakes get captured in sacks and I've wondered if the snake would get dizzy if the sack were twirled around. I have not done any tests (and don't plan to) because snakes scare me.