The study of the normal function of living organisms and the means by which it is achieved.

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Deep diving in mammals

Mammals like seals often dive and can remain under water for more than 70 minutes. How do seals know when is it the time to come up?
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How does the cell regulate different metabolic pathways?

I heard somewhere that cells use different nucleosides bound to triphosphates e.g. ATP, GTP, CTP and other modified compounds: NADH, NADPH to distinguish between different metabolic pathways and so ...
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39 views

Does the cellular response to every receptor work the same way?

I heard somewhere that activating any receptor results in the same intracellular response (signaling) which involves NF-κB. If that is true, I hardly understand how the cells distinguish between ...
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77 views

What is the difference between rheobase and threshold?

Neuronal tissues can be excited by electrical stimulation. Two commonly encountered characteristics for electrically stimulating nerve cells is the threshold and the rheobase. My question is what the ...
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35 views

What makes certain obligate anaerobes viable in fermentation starter cultures?

If Propionibacterium are obligate anaerobes (to wit, poisoned by oxygen), what makes 'Dairy' or classical propionibacteria (e.g. P. shermanii, P. jensenii, P. acidicpropionici, et al) viable in ...
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53 views

Why does crying lead to a running nose and reddened nose tip?

Why do we have a running nose for quite some time after crying? It persists even after we stop crying. Why is it so? I have faced this always. Also, why does our nose redden on crying for long?
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63 views

Fast standing and the heart's insufficient accommodation of the increased venous return

Assume you are 45 minutes on the supine position. Furthermore: you stand all of a sudden and fast and without sympaticus activity. The venous return (smooth musculature of vessels) accommodates ...
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175 views

Why do the humans become sleepy after meals?

I don't know about all the mankind, but I know enough people, who becomes sleepy after their meals. Also, I'm not sure, what kind of food do they consume, but I personally get sleepy almost from any ...
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165 views

Correlation between muscle size and absolute strength

Is there a linear connection between muscle size and the power it can produce? If not, why? And what is the true correlation if any, can it be described with an appropriate function? What other ...
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85 views

Sodium levels and blood pressure

Why does low Na+ levels cause hypotension (low blood pressure). Alternatively, why does excessive intake of Na+ cause hypertension or high blood pressure? From what I understand, there are ...
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66 views

What happens during a Raynauds episode?

Raynaud's phenomenon can be a serious health issue, as the blood flow to the extremities, mainly the fingers is compromised, causing fingers to blanche, and then turn blue. Severe Raynaud's can cause ...
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55 views

Antibody production in secondary immune response

Can IgG antibodies be produced in the secondary immune response without the help of T cells? Is the affinity of antibody for antigens higher during secondary immune response?
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423 views

Why is the blood pressure in the superior vena cava during inhalation less than during the exhalation?

For further investigation into the progress of the blood pressure, we will measure a patient's blood pressure in the superior vena cava measured during inhalation and during an exhalation. His heart ...
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57 views

What is the mechanism behind ventilatory acclimatization?

In my respiratory physiology lectures, my professor explained that hypoxia-induced hyperventilation occurs in 2 stages when people try to acclimate at high altitudes. My question is about the ...
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2k views

What is the “lifecycle” of an average eschar and what types of cells are involved in each stage?

(after some deliberation in the comments, I've decided to make the question more general) An eschar or "dry scab" often forms at a site of injury over a large cut or sore. It seems as though the ...
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37 views

Biology Experiment Data (Hodgkin-Huxley)

I'm doing research into the Hodgkin-Huxley Model from an electronics/mathematics perspective and I'm looking to find actual numerical results from experiments on squid axons. I want to compare the ...
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46 views

Relationship between mN and mg in vessel contraction studies?

What is the relationship between mN and mg as the units involved to measure the changes in contraction? A tool most widely used is an instrument called myograph. In these exoeriments, either units of ...
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27 views

What does salt do to styes?

Styes formed in the eyes are cured by dabbing at them with lukewarm water(I saw this being done many a times as a home remedy.) At times, common salt is added to the water before dabbing. My mother ...
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57 views

Why does skin sometimes suddenly itch when you stretch it? [closed]

Sometimes, when I bend over, areas of my skin like my back can suddenly itch quite intensely. Sometimes it may be another part of my body and the pattern seems to be a part of the skin organ that is ...
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47 views

How well do we notice asynchronicity?

I'm stopped at a stoplight and, with nothing to do, my thoughts wander to the timed don't-walk sign that governs any pedestrians who might wish to cross the street I'm driving along. I can see two ...
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1answer
380 views

Which is the tissue damaging agent in krokodil (street desomorphine)

I've just read about krokodil and saw some quite hideous pictures about what it does to the human body. I guess just desomorphine alone wouldn't have this effect. Which ingredient(s) causes the ...
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81 views

Size of classical liver lobule across species

A classical liver lobule is made up of a central vein and the portal triads. A typical human liver weighs around 3 lbs. , while a typical bovine liver weighs around 12 lbs. I was wondering if anyone ...
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1k views

Does Darwin's Theory of Evolution refute Terence McKenna theory “Stoned Ape” theory of human evolution?

I haven't read it but I'm asking for a quick answer. As far as I know, Terence McKenna's theory of evolution in humans main concept is that a hominid has tried in their diet psilocybin mushrooms, and ...
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237 views

What difference does it make in the organism's physiology/metabolism whether oxygen binds reversibly or not?

A follow-up to How does hemoglobin-free blood transport oxygen? I'm unsure about the use of physiology/metabolism in the title there. The question in mind is whether this reversible binding makes an ...
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2answers
231 views

What gases are needed for humans to breathe?

I will be beginning a science project about sustaining life on space stations. I already know that pure oxygen is harmful for humans but would $O_2$ + $CO_2$ be enough for humans to breathe in or do ...
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1answer
53 views

What are the risks of elevating the legs too regularly and when tired?

I started to to think the pathophysiology of elevating legs high next to the wall too often and when you are tired. I think possible manifestations some damage to valves of the veins (No!) because ...
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41 views

Gastro-intestinal physiology reference

I am a physicist but I have always wanted to understand how my digestion takes place in as much detail as possible. I have no idea about books or reference on the subject of Gastro-intestinal and ...
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46 views

What is ischaemia exactly?

I think it is decreased blood supply to organs and tissues. I also think it is the stopped circulation. However, both ones cannot be right, I think. What is ischaemia exactly?
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159 views

What is the energy balance of cooking?

If I cook some food, I get apparently several energetic advantages: thermal : the temperature of the food is closer or superior to the temperature of my body or internal organs, so I do not have to ...
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3answers
86 views

Are all healthy animals more likely to defecate near the end of a rest-cycle?

Just what the title states. It stems from observation & personal experience that a person/dog/cat/monkey is more likely to relieve oneself immediately after it wakes up from the peak-sleep cycle ...
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1answer
89 views

Why do humans have only one liver? [closed]

Humans have two lungs, two kidneys... But only one liver. If the liver is vital to our survival, why do humans only have one?
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31 views

Is the sense for salt depending on the electrolyte level in our body?

I often noticed, after (heavy) physical activity like cycling, running, swimming or working an isotonic drink (to recover the electrolyte level) tastes less "salty" compared to when drinking it before ...
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1answer
28 views

How are cyclic hormones characterized?

I have a question regarding the description of a subset of peptide hormones, called cyclic hormones. Two examples of cyclic hormones would be somatostatin and melanin-concentrating hormones. I know ...
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1answer
52 views

Could light/occasional smoking strengthen the lungs?

Here's my thought process, correct me where I'm wrong. It seems the human body has thresholds. Examples: You lift too much weight, and the muscles and tendons risk serious injury, but otherwise ...
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65 views

Advantage of cup-like shape of blood cells, spores?

Mold spores sometimes have the same shape as platelets in blood. If I were designing a spore it would probably be spherical. Is there any advantage to this cup-like shape? Maybe there is some ...
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62 views

Why are new vessels more permeable in microvasculature?

I know for microvasculature New microvasculature (arterioles, venules) are always more permeable as they lack pericytes. and then I have this sentence about new blood vessels (not specific) ...
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1answer
1k views

Are there more/less favourable phases of menstrual cycle to donate blood?

I was wondering whether it makes a difference when during the menstrual cycle a female is donating blood in terms of: Blood quality (iron or hormones levels) Her health/safety I am aware that ...
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2answers
56 views

Resilience to the neurotoxins of Indian King Cobra

I read on Wikipedia about this: King Cobra - Wikipedia In Thailand, a concoction of alcohol and the ground root of turmeric is ingested, which has been clinically shown to create a strong ...
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46 views

How Ants know about Earthquake?

How does an ant know about Earthquake is it because of an organ or due to other factors?
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52 views

Can tubular secretion regarded as local hormone?

Tubular secretion is : The process in which ions and other waste products are transported into the distal tubules of the nephron. can it be regarded as local hormone??
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33 views

How does a blunt force stimulate histamine to develop early stages of inflammation?

I know that viruses and sharp forces can stimulate mast cells by cut or by a virus infecting them and then release histamine. How can blunt force do this and cause inflammation? It doesn't have the ...
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37 views

Sitting much, thrombosis and hypoxia

I am thinking the more reasons why sitting much lead to thrombosis i.e. clotting of blood in blood vessels and then hypoxia in the deep tissues eventually. What are the physiological mechanisms for ...
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23 views

To understand synthesis of e-NOS and n-NOS with respect to Ca and calmodulin

I found this sentence in my notes interesting E-NOS and n-NOS are Ca-calmodulin dependent ferments. They are synthesized in small concentration as a response to physiological signals which ...
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1answer
537 views

Can food swallowed when a person is upside down reach the stomach?

If a person positions himself upside down and swallows food, will it reach the stomach against gravity? If so how?
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1answer
23 views

Is Norepinephrine beta2 adrenomimetic?

I know that it has alpha1, alpha2 and beta1 effects. It has beta2 receptor where epinephrine can effect. However, to say that it is beta adrenomimetic, I am not sure. That is ligand binding beta2 ...
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37 views

Why is LH level much higher than FSH level at ovulation?

My teacher showed us an elaborate collection of graphs with one of them showing FSH and LH plasma levels during the menstrual cycle. LH level was almost 3 times higher than FSH level. Why? Does this ...
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43 views

All or nothing phenomena

We know that an action potential is produced by an active cell membrane when the stimulus reaches a certain threshold. When it does, an action potential fires, and when it doesn't, nothing happens. ...
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61 views

brain activity responsible for imagination

Which part of brain is responsible for advance or unseen imagination For example:ones brain can make a situation in mind which is impossible to happen ...which part of brain is hyper active?
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1answer
25 views

What triggers the release of gonadotrophin-releasing hormone with the onset of puberty?

I am interested to know the process of development of puberty. During puberty, when boys/girls reache 12-14 (puberty) years of their age, their hypothalamus releases gonadotropin releasing hormone ...
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101 views

Why the scent of mouth gets dirty after not eating for a long time?

After a long time of hard workout,not eating and nervousness makes your taste and scent of mouth very uncomfortable and bad why this happens and is there any way to prevent it?