The study of the normal function of living organisms and the means by which it is achieved.

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Difference between facilitated diffusion and secondary active transport in cells

Specifically, what is the difference between facilitated diffusion carrier processes (passive transport) and secondary active transport co-transport processes (active transport)? They seem to be the ...
2
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1answer
49 views

How to define drug-resistant or -sensitive cell line when knowing the IC50 values?

I have got the IC50 data for a drug on different cell lines. How to define if the cell line is sensitive or resistant towards this drug? Could anyone tell me how to define this?
2
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1answer
18 views

How is circadian rhythm of gastric acid secretion regulated?

Gastric acid secretion shows a circadian rhythm where acid production in the morning is minimal and it reaches a maximum towards the evening. How is this process regulated?
2
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1answer
42 views

Is Norway spruce (Picea abies (L.) Karst.) isohydric or anisohydric species?

Question from a thesis defense list ask me this. But I can't find the exact answer on the internet or in books. In my thesis, I described isohydric plants, for example maize, lupin, pea, poplar. This ...
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1answer
40 views

Why is the resting potential of a neuron so close to the equilibrium potential of K⁺?

I know this has something to do with the K+ leak channel. I just don't understand how. I know that 3 Na+ are pumped out for every 2 K+ pumped in. This makes the cell interior net negative. I know ...
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2answers
73 views

How does the cell regulate different metabolic pathways?

I heard somewhere that cells use different nucleosides bound to triphosphates e.g. ATP, GTP, CTP and other modified compounds: NADH, NADPH to distinguish between different metabolic pathways and so ...
2
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1answer
337 views

What is the difference between rheobase and threshold?

Neuronal tissues can be excited by electrical stimulation. Two commonly encountered characteristics for electrically stimulating nerve cells is the threshold and the rheobase. My question is what the ...
2
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2answers
113 views

Is there a known glucosepane cross-link breaker?

I read the following on wikipedia: There is, however, no agent known that can break down the most common AGE, glucosepane, which appears 10 to 1,000 times more common in human tissue than any ...
2
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1answer
41 views

What makes certain obligate anaerobes viable in fermentation starter cultures?

If Propionibacterium are obligate anaerobes (to wit, poisoned by oxygen), what makes 'Dairy' or classical propionibacteria (e.g. P. shermanii, P. jensenii, P. acidicpropionici, et al) viable in ...
2
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1answer
91 views

Why does crying lead to a running nose and reddened nose tip?

Why do we have a running nose for quite some time after crying? It persists even after we stop crying. Why is it so? I have faced this always. Also, why does our nose redden on crying for long?
2
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1answer
77 views

Fast standing and the heart's insufficient accommodation of the increased venous return

Assume you are 45 minutes on the supine position. Furthermore: you stand all of a sudden and fast and without sympaticus activity. The venous return (smooth musculature of vessels) accommodates ...
2
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2answers
145 views

Calcium levels and nerve hyperexcitation

Why does lower blood calcium levels (or lower calcium levels in ECF) cause nervous hyperexcitaton? Why does it cause over stimulation of nerves and muscles and spasmic contractions of muscles? This is ...
2
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1answer
113 views

Sodium levels and blood pressure

Why does low Na+ levels cause hypotension (low blood pressure). Alternatively, why does excessive intake of Na+ cause hypertension or high blood pressure? From what I understand, there are ...
2
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1answer
75 views

What happens during a Raynauds episode?

Raynaud's phenomenon can be a serious health issue, as the blood flow to the extremities, mainly the fingers is compromised, causing fingers to blanche, and then turn blue. Severe Raynaud's can cause ...
2
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1answer
60 views

Antibody production in secondary immune response

Can IgG antibodies be produced in the secondary immune response without the help of T cells? Is the affinity of antibody for antigens higher during secondary immune response?
2
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1answer
178 views

Need of Creatinine Phosphate

In muscle cells most of the ATP's phosphate is with creatinine phosphate. So why is the displacement of the phosphate group done ? Is it because creatinine phosphate would give it's phosphate more ...
2
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1answer
488 views

Why is the blood pressure in the superior vena cava during inhalation less than during the exhalation? [closed]

For further investigation into the progress of the blood pressure, we will measure a patient's blood pressure in the superior vena cava measured during inhalation and during an exhalation. His heart ...
2
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1answer
86 views

What is the mechanism behind ventilatory acclimatization?

In my respiratory physiology lectures, my professor explained that hypoxia-induced hyperventilation occurs in 2 stages when people try to acclimate at high altitudes. My question is about the ...
2
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1answer
2k views

What is the “lifecycle” of an average eschar and what types of cells are involved in each stage?

(after some deliberation in the comments, I've decided to make the question more general) An eschar or "dry scab" often forms at a site of injury over a large cut or sore. It seems as though the ...
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2answers
43 views

What is the difference between meristem and bud?

Keep reading both terms quite frequently while studying plant physiology. I did some research trying to establish their differences and I learnt that meristems are undifferentiated cells that can ...
2
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0answers
52 views

Biology Experiment Data (Hodgkin-Huxley)

I'm doing research into the Hodgkin-Huxley Model from an electronics/mathematics perspective and I'm looking to find actual numerical results from experiments on squid axons. I want to compare the ...
2
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0answers
41 views

What does salt do to styes?

Styes formed in the eyes are cured by dabbing at them with lukewarm water(I saw this being done many a times as a home remedy.) At times, common salt is added to the water before dabbing. My mother ...
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0answers
775 views

Why does skin sometimes suddenly itch when you stretch it? [closed]

Sometimes, when I bend over, areas of my skin like my back can suddenly itch quite intensely. Sometimes it may be another part of my body and the pattern seems to be a part of the skin organ that is ...
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0answers
40 views

How do the symptoms of Sepsis affect heart function?

I have intuition that Sepsis with infection can cause spastic functioning of heart during systole heart working spontaneously in snatches during systole atrial fibrillation first contraction of ...
2
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1answer
419 views

Which is the tissue damaging agent in krokodil (street desomorphine)

I've just read about krokodil and saw some quite hideous pictures about what it does to the human body. I guess just desomorphine alone wouldn't have this effect. Which ingredient(s) causes the ...
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0answers
1k views

What are potential side effects of myostatin inhibitors?

Myostatin inhibitors, which are being developed to treat muscle wasting diseases like muscular dystrophy, are likely to be abused by athletes. What are the potential long-term side-effects of taking a ...
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0answers
104 views

Size of classical liver lobule across species

A classical liver lobule is made up of a central vein and the portal triads. A typical human liver weighs around 3 lbs. , while a typical bovine liver weighs around 12 lbs. I was wondering if anyone ...
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3answers
1k views

Does Darwin's Theory of Evolution refute Terence McKenna theory “Stoned Ape” theory of human evolution?

I haven't read it but I'm asking for a quick answer. As far as I know, Terence McKenna's theory of evolution in humans main concept is that a hominid has tried in their diet psilocybin mushrooms, and ...
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3answers
282 views

What difference does it make in the organism's physiology/metabolism whether oxygen binds reversibly or not?

A follow-up to How does hemoglobin-free blood transport oxygen? I'm unsure about the use of physiology/metabolism in the title there. The question in mind is whether this reversible binding makes an ...
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1answer
60 views

Gastro-intestinal physiology reference

I am a physicist but I have always wanted to understand how my digestion takes place in as much detail as possible. I have no idea about books or reference on the subject of Gastro-intestinal and ...
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2answers
346 views

What gases are needed for humans to breathe?

I will be beginning a science project about sustaining life on space stations. I already know that pure oxygen is harmful for humans but would $O_2$ + $CO_2$ be enough for humans to breathe in or do ...
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1answer
22 views

What is the so called “hepatic glucose production”

I came across this term in my readings but I do not understand how this works. Can someone direct me to some reference as to what this "hepatic" glucose production is all about?
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1answer
198 views

What are the risks of elevating the legs too regularly and when tired?

I started to to think the pathophysiology of elevating legs high next to the wall too often and when you are tired. I think possible manifestations some damage to valves of the veins (No!) because ...
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1answer
46 views

What is ischaemia exactly?

I think it is decreased blood supply to organs and tissues. I also think it is the stopped circulation. However, both ones cannot be right, I think. What is ischaemia exactly?
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1answer
179 views

What is the energy balance of cooking?

If I cook some food, I get apparently several energetic advantages: thermal : the temperature of the food is closer or superior to the temperature of my body or internal organs, so I do not have to ...
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3answers
90 views

Are all healthy animals more likely to defecate near the end of a rest-cycle?

Just what the title states. It stems from observation & personal experience that a person/dog/cat/monkey is more likely to relieve oneself immediately after it wakes up from the peak-sleep cycle ...
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2answers
359 views

Why can newborns swim?

I am wondering for someone to discuss the phenomena that newborn babies (humans) are able to submerge underwater up until a few months where that ability is lost again? What is the explanation for ...
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1answer
40 views

How does ANF increase GFR?

ANF as we know reduce the Na+ uptake and K+ removal in the distal tubules and it also functions as a Vasodialator (?) But again it says that ANF increases the Glomerular filtrate ? But if it is acting ...
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1answer
36 views

Is the sense for salt depending on the electrolyte level in our body?

I often noticed, after (heavy) physical activity like cycling, running, swimming or working an isotonic drink (to recover the electrolyte level) tastes less "salty" compared to when drinking it before ...
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1answer
30 views

How are cyclic hormones characterized?

I have a question regarding the description of a subset of peptide hormones, called cyclic hormones. Two examples of cyclic hormones would be somatostatin and melanin-concentrating hormones. I know ...
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1answer
64 views

Could light/occasional smoking strengthen the lungs?

Here's my thought process, correct me where I'm wrong. It seems the human body has thresholds. Examples: You lift too much weight, and the muscles and tendons risk serious injury, but otherwise ...
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1answer
208 views

Advantage of cup-like shape of blood cells, spores?

Mold spores sometimes have the same shape as platelets in blood. If I were designing a spore it would probably be spherical. Is there any advantage to this cup-like shape? Maybe there is some ...
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1answer
74 views

Why are new vessels more permeable in microvasculature?

I know for microvasculature New microvasculature (arterioles, venules) are always more permeable as they lack pericytes. and then I have this sentence about new blood vessels (not specific) ...
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1answer
2k views

Are there more/less favourable phases of menstrual cycle to donate blood?

I was wondering whether it makes a difference when during the menstrual cycle a female is donating blood in terms of: Blood quality (iron or hormones levels) Her health/safety I am aware that ...
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3answers
93 views

Does the necessary Carbon Dioxide need to be in the atmosphere for mammals?

In the answers to this question, we've learnt that carbon dioxide is necessary for mammalian life, but is it necessary in the atmosphere/to breathe it in? Or does the act of respiration give a ...
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1answer
44 views

Double use of ATP in relaxing myosin & active transportation of calcium?

Is the ATP molecule which is bound to the myosin head for relaxation of the muscle (i.e., to break the cross bridge) also utilized for active transport of calcium to the sarcoplasmic reticulum during ...
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1answer
64 views

What specific sensory nerves act as receptors for “pins and needles” (neuropathy)?

According to this excellent answer, the difference between "pain" and "pins and needles" (neuropathy) is that different receptors (sensory nerves) trigger in reaction to different stimuli. Different ...
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1answer
130 views

Duplicity Vs. Singularity of Mammals Organs [closed]

Are there known evolutionary reasons why mammals contain 2 of some organs (such as lungs and kidneys) and only 1 of some (such as liver)?
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1answer
71 views

How Ants know about Earthquake?

How does an ant know about Earthquake is it because of an organ or due to other factors?
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1answer
61 views

Can tubular secretion regarded as local hormone?

Tubular secretion is : The process in which ions and other waste products are transported into the distal tubules of the nephron. can it be regarded as local hormone??