The study of the normal function of living organisms and the means by which it is achieved.

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56 views

Which chemical and hormonal effects on heart are by metabolites? [closed]

I am thinking which hormonal and chemical effects from: catecholamines thyroxin corticosteroids sex hormones prostaglandins Ca2+ Na+ K+ can be be regarded as metabolites i.e. intermediates or ...
1
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1answer
87 views

Why are new vessels more permeable in microvasculature?

I know for microvasculature New microvasculature (arterioles, venules) are always more permeable as they lack pericytes. and then I have this sentence about new blood vessels (not specific) ...
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1answer
49 views

What is ischaemia exactly?

I think it is decreased blood supply to organs and tissues. I also think it is the stopped circulation. However, both ones cannot be right, I think. What is ischaemia exactly?
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1answer
189 views

What is the difference between intracardiac and extracardiac reflexes in cardiac regulation?

The primary parameters of heart pumping are strength of contractility (inotropic positive; Frank-Starling relationship) rate of relaxation (lusitropic positive) heart rate (chronotropic positive) ...
0
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1answer
56 views

Do's and Don't's of Undergraduate Research? [closed]

I was fortunate enough to get a position as a researcher for the Mayo Clinic's SURF Program this year. My PI's lab focus is on the the immune system's role in CNS axonal and neuronal injury, ...
3
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2answers
183 views

Electronic cigarettes (e-cigs), any health risks?

Background: An electronic cigarette (e-cig or e-cigarette) is a battery-powered device which simulates tobacco smoking patented in 1963 by Herbert A. Gilbert. It generally uses a heating element ...
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0answers
61 views

Nearly Exhaustive List for Cholesterol Pathways [closed]

I have run across an interesting case that is similar to only two others I've encountered. What makes it interesting is the combination of undetectable (under normal testing conditions, can elaborate ...
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1answer
405 views

Can too low oncotic pressure lead to Third spacing and Edema?

I know that low oncotic pressure is associated with many pathologies. I am interested how it is associated with Third spacing. My professor says that it can permit edema formation. The opposing ...
4
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1answer
130 views

Why do humans circulate monosaccharides instead of disaccharides as in plants?

Plants transport food mostly in the form of disaccharides like sucrose but humans transport them in the form of a monosaccharide - glucose. What is the reason behind this ?
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1answer
84 views

Late control mechanisms of blood pressure (arterial) level? [closed]

I first covered the fast and moderate control mechanisms which I think are Fast control: Baroreceptive reflex (tonus), Chemoreceptive reflex (CO$_2$). Moderate control: Bicarbonate (ECF), ...
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1answer
4k views

Which processes are during the latent period of ventricular contraction?

The latent period is the time between the start of depolarisation and the start of contraction. I know that the contraction of ventricles starts after sufficient influx of Ca2+ and threshold ...
1
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1answer
170 views

Is end-systolic volume (ESV) the same as residual volume?

I am reading this site and my study materials. The end-systolic volume (ESV), 50-60 ml, is the volume of blood found in ventricles after systole and contraction of ventricles. I think ESV is the same ...
3
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1answer
135 views

What is lack in sense of smell called?

People who lack the sense of hearing, vision and speaking are called Deaf, Blind and Mute. But what is the person called if he/she lacks the sense of smell? Is there any case like that?
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2answers
59 views

Is there any format for official Physiological/Medicine answers? [closed]

Assume you have an exam which has 5 extensive questions and 60 minutes. You do not have time to cover most if you write everything in essay format. If you start to write essays, you do not really have ...
0
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1answer
53 views

Which processes are included in the process called cells eating themselves?

I am reading about atrophy and I am thinking to which processes the phrase cells eating themselves refer to. Cells need something to survive these difficult times. To decrease protein synthesis ...
2
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1answer
55 views

Does Sirtuin protein family Sir2 work in low-calorie diet mostly?

I am reading about the protein family in relation to the prolongation of cell life. It is known that Sirtuins have been implicated in influencing a wide range of cellular processes like ageing, ...
1
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1answer
50 views

Sitting much, thrombosis and hypoxia

I am thinking the more reasons why sitting much lead to thrombosis i.e. clotting of blood in blood vessels and then hypoxia in the deep tissues eventually. What are the physiological mechanisms for ...
0
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1answer
174 views

Regional circulation and Cardiac output? [closed]

I am reading my study materials and think what is the systemic POV here Regional circulation Blood flow within the tissue/organs based on the functional demands of the tissue. E.g. The ...
3
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2answers
504 views

Correlation between muscle size and absolute strength

Is there a linear connection between muscle size and the power it can produce? If not, why? And what is the true correlation if any, can it be described with an appropriate function? What other ...
0
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2answers
76 views

To understand Second messenger signalling in I/c and E/c

I found this picture in my study materials. I think it is too schematic and ignores the big pictures. I think the thing connected to the hormone is receptor. The second messanger is then connected ...
0
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1answer
303 views

Can you approximate Cardiac Output by Ohm's law?

I found this sentence from my notes which I cannot understand PR < CO, CO $\uparrow$, PR > CO $\downarrow$ where ...
1
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1answer
101 views

Physiology of skin and leather: why do salt borders occur?

I discussed a leather store about the white border aka salt border on leather shoes. They said that it is due to inner features of leather and you could try to add some fat/cream to push it back ...
0
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1answer
131 views

Can pheromones in perfume be formulated to cause agitation? [closed]

I generally don't care for female perfume. I have very sensitive olfactory receptors and in general, I just find perfume overwhelming. A couple weeks ago, my wife of almost 14 years and I were ...
4
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1answer
47 views

What are the molecular mechanisms that make the turtle brain more resistant to hypoxia?

I know that turtle brains, particularly those of individual species that hibernate and burrow are particularly resilient to hypoxia and any tissue damage secondary to a hypoxic event. What are the ...
4
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1answer
292 views

Why apes started to contemplate and become altruistic? [closed]

I was asking this first on philosophy forums, but it is suggested, that answer could be found from evolutionary view of point, so here we go: Again my question raised when thinking of myths, their ...
1
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1answer
98 views

What stops the coagulation process?

Whenever there are minor/major injury to blood vessels, the platelets, fibrin, thrombin, etc. are recruited. They then seal the wound and block bleeding. What tells them that their job is done?
2
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1answer
2k views

What is the physiological difference between snorting/swallowing cocaine

I know that mucosa inside the nose absorbs cocaine molecules when snorting cocaine, but what difference is there compared to swallowing? Also more cocaine administration equals more cocaine molecules ...
6
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2answers
102 views

Is the empty GI tract a hollow tube with air inside, or is it generally collapsed until food is eaten?

I have heard that "air in the GI tract" results in flatulence and burping etc, however I initially assumed that the "empty" GI tract was a hollow tube filled with air anyway. So on an empty stomach ...
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1answer
94 views

Death because of no radio waves [closed]

I read somewhere that a man dies if he is isolated from natural electromagnetic fields and waves. (I imply fields of radio frequencies and below.) Is it true?
4
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2answers
2k views

The number of nipples (breasts) a species has?

Only mammals have mammaries and mammary glands. What evolutionary factors determines the number of mammaries (nipples/teats/breasts) a species has? Is it always an even number?
2
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1answer
1k views

Excretion of various wastes and water requirement

A common fact is that Ammonia, Urea and Uric acid are the most common excreted metabolites and their removal needs varying amount of water, highest for ammonia (hence suited only for aquatic animals) ...
3
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1answer
450 views

Is there a maximum pain threshold?

Is there a maximum threshold of pain a Human can experience, beyond which point there is no noticeable difference? I ask this question in part to better understand the definition of pain and its ...
4
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1answer
71 views

How much can you learn about species variation from a skeleton?

I just read about the discovery of the 1.8-million-year-old human skull in Georgia, and how it suggests that early humans were all one species instead of distinct ones. Would an archaeologist ...
0
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1answer
28 views

Order of events in hibernation

Arrange this in sequence : i. Heat loss exceeds heat production. ii.As body temperature falls, heat loss decreases. iii.Body temperature equals environmental temperature. ...
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3answers
2k views

Does Darwin's Theory of Evolution refute Terence McKenna theory “Stoned Ape” theory of human evolution?

I haven't read it but I'm asking for a quick answer. As far as I know, Terence McKenna's theory of evolution in humans main concept is that a hominid has tried in their diet psilocybin mushrooms, and ...
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1answer
100 views

(Web)app to search metabolic/signalling pathways

I'm looking for an application where you can find pathways by selecting a chemical occurring in it. So, for example, selecting 6-phosphogluconolactone brings up the pentose phosphate pathway or any ...
3
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1answer
133 views

Why does hypertension occur in obstructive sleep apnea?

What is the physiological mechanism behind systemic hypertension resulting from obstructive sleep apnea?
6
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1answer
248 views

Understanding Membrane / Resting Potential from the perspective of ions?

From wikipedia article RESTING potential: "there is no actual measurable charge excess in either side. That occurs because the effect of charge on electrochemical potential is hugely greater than ...
12
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1answer
139k views

What causes random long white body hairs?

I'm sure many of you have experienced this - you scratch your back or brush your hand over your arm and find a ridiculously long thin white hair, sometimes as long as 3 or 4 inches. I know a few ...
3
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1answer
141 views

Attachment of muscles during molting in insects

Normally, insects' muscles are attached to their exoskeleton but what happens to this attachment when they are moulting? Sorry if this is an extremely silly question but I have wondered about it for ...
2
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1answer
64 views

Antibody production in secondary immune response

Can IgG antibodies be produced in the secondary immune response without the help of T cells? Is the affinity of antibody for antigens higher during secondary immune response?
3
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1answer
75 views

Alternating Ovulation

I have often heard that right and left ovaries alternate in releasing ovum. Is it always true? What controls this rhythm? Is it simply because the other ovary is unresponsive to LH or FSH? If so, ...
3
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1answer
254 views

Need of Creatinine Phosphate

In muscle cells most of the ATP's phosphate is with creatinine phosphate. So why is the displacement of the phosphate group done ? Is it because creatinine phosphate would give it's phosphate more ...
3
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1answer
51 views

Effect of arteriole dilation on vein

If an arteriole leading to a capillary bed is dilated will the pressure in the vein coming out from the bed decrease ? Will the velocity of blood in the vein change ?
2
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1answer
454 views

Which is the tissue damaging agent in krokodil (street desomorphine)

I've just read about krokodil and saw some quite hideous pictures about what it does to the human body. I guess just desomorphine alone wouldn't have this effect. Which ingredient(s) causes the ...
5
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1answer
436 views

Skeletal muscles in clam

Although skeletal muscle fatigues fairly rapidly, clams have a protein called paramyosin that allows them to sustain contractions for up to a month. What might be the role of paramyosin at the ...
20
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1answer
23k views

Why is coffee a laxative?

How does caffeine (or any additional agents) act as a laxative when ingested? I'm interested in the metabolic/signaling pathway.
0
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1answer
74 views

Which fish will have more developed gills?

A fish lives at the depth of 1000-2000m and another at the depth of 200-700m. Which of them would have a more developed gill system ?
0
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1answer
177 views

All or none phenomenon

Let's say that the threshold potential of a neuron is +40 mV to make a muscle twitch. Now suppose we have two signals of +20 mV. So, this signal will cause the twitch in muscle because it has reached ...
0
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1answer
269 views

Is the resting state of the forearm in the pronated or supinated position?

It seems to me that my forearm is naturally in a more pronated position than the anatomic (supinated) position and that it actually takes work to make it hold the supinated position. Anyone an expert ...