The study of the normal function of living organisms and the means by which it is achieved.

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Mechanism of Muscle Growth

According to this video (sorry for the poor reference but it represents my level of understanding in physiology), muscle grow as a consequence of repairing micro-lesions. How are these micro-lesions ...
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98 views

Dimensionless number for blood volume

Comments from the question How is the blood volume of a living organism measured without killing it? by @Nico discussed that the time of blood recirculation scales with the size of the organism. I was ...
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41 views

Are small CO2 concentrations devastating to certain cognitive tasks?

A new study shows strong effects of what should be a negligible CO2 concentration. The paper "Is CO2 an Indoor Pollutant? Direct Effects of Low-to-Moderate CO2 Concentrations on Human Decision-Making ...
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66 views

A day in Beijing is like smoking Only one sixth of a cigarette

This is the title of this blog post followed by this other good post. I'm particularly anti-tobacco-smoke, at the point of not always considering other pollution, and this article shows how this kind ...
3
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0answers
129 views

How is membrane capacitance related to the increased speed of saltatory conduction?

Here is the original question which inspired my question below. As explained by the answers there, the reason saltatory conduction in myelinated neurons is faster than non-myelinated conduction is ...
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85 views

What are the physiological effects of wine?

I have read that alcohol in general and wine in particular can have advantageous as well as detrimental effects on human health. Is this true? What are the physiological effects of consuming wine in ...
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0answers
47 views

Patch-Clamping Neurons Resources

Are there any lectures available on Patch-Clamping? Were can I find a mathematical model of Patch-Clamp? (that can be easily implemented in matlab). I have found some step-by-step protocols on ...
3
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0answers
54 views

Physiological or molecular difference before and after sleep?

I know that the details of the process of sleep aren't entirely known, but have always wondered why I feel rested after sleep. Biologically, what differences can be directly observed in the human ...
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24 views

Biology Experiment Data (Hodgkin-Huxley)

I'm doing research into the Hodgkin-Huxley Model from an electronics/mathematics perspective and I'm looking to find actual numerical results from experiments on squid axons. I want to compare the ...
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40 views

Relationship between mN and mg in vessel contraction studies?

What is the relationship between mN and mg as the units involved to measure the changes in contraction? A tool most widely used is an instrument called myograph. In these exoeriments, either units of ...
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23 views

What does salt do to styes?

Styes formed in the eyes are cured by dabbing at them with lukewarm water(I saw this being done many a times as a home remedy.) At times, common salt is added to the water before dabbing. My mother ...
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45 views

How well do we notice asynchronicity?

I'm stopped at a stoplight and, with nothing to do, my thoughts wander to the timed don't-walk sign that governs any pedestrians who might wish to cross the street I'm driving along. I can see two ...
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69 views

Would my hands sweat this much if I wasn't wearing gloves?

I've wondered about this for a long time, and hopefully someone here has a reasonable answer. I'm a cell and molecular biologist, and much of my time at the bench is spent wearing (usually nitrile) ...
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78 views

Size of classical liver lobule across species

A classical liver lobule is made up of a central vein and the portal triads. A typical human liver weighs around 3 lbs. , while a typical bovine liver weighs around 12 lbs. I was wondering if anyone ...
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32 views

Why is an inflammation in eye and brain more devastating and can lead to loss of organ function compared to other organ like liver etc.?

Recently I have learnt something about immunoprivileged site and I wonder why these sites like eye would prefer tolerating these antigens that sabotages the normal function of these to having ...
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22 views

Can non-carbonated energy drinks boost alcohol intoxication?

I just read news article about banning caffeine in alcohol drinks and about that energy drinks increase the urge to drink alcohol. Energy drinks cause sugar intoxication - answer about it here ...
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18 views

Effect of lower back on Lymphatic drainage in Posterior Lumbalis

I am studying how the muscle spasm of lower back can affect the anterior lymphatic drainage in a male obese situation (supine position) and quality of sleep. There seems to be very little lymphatic ...
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39 views

Vitamin D oral intake, transportation and absorption

Several factors affecting vitamin D and its active form absorption and storage acidity of stomach (not significant effect) cytopathic effects of viruses cytopathic effects of bacteria where the ...
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37 views

What is the nature of action potentials in autonomic nervous system?

My conjuncture is that the natures of sympathetic and parasympathetic action potentials are different. My findings propose me that sympathetic action potential is little longer lasting than ...
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32 views

How do the symptoms of Sepsis affect heart function?

I have intuition that Sepsis with infection can cause spastic functioning of heart during systole heart working spontaneously in snatches during systole atrial fibrillation first contraction of ...
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31 views

Nearly Exhaustive List for Cholesterol Pathways

I have run across an interesting case that is similar to only two others I've encountered. What makes it interesting is the combination of undetectable (under normal testing conditions, can elaborate ...
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30 views

Voltage-gated Potassium channels in the action potential of cardiomyocyte?

There is one type of potassium voltage-gated channels open in Phase 1 too. Some call them early repolarization channels. I am not convinced that the channels are different in different phases: 0, 2, ...
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49 views

Calcium levels and nerve hyperexcitation

Why does lower blood calcium levels (or lower calcium levels in ECF) cause nervous hyperexcitaton? Why does it cause over stimulation of nerves and muscles and spasmic contractions of muscles? This is ...
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73 views

Sodium levels and blood pressure

Why does low $\ce{Na+}$ levels cause hypotension (low blood pressure). Alternatively, why does excessive intake of $\ce{Na+}$ cause hypertension or high blood pressure? From what I ...
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20 views

Amphibian blood circulation

In an amphibian blood entering the right atrium shows higher levels of oxygenation than that in left atrium when : A.It is hyperactivated B.it is hibernating C.it is submerged D.it is in the ...
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63 views

Why delayed Power nap might degrade our night sleep?

Recently in the research areas we come across the term "Power Nap" which says after a nice lunch it would be nice to get a nap for 20-30 minutes which will make the body relaxed and fresh afterwards. ...
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1k views

What are potential side effects of myostatin inhibitors?

Myostatin inhibitors, which are being developed to treat muscle wasting diseases like muscular dystrophy, are likely to be abused by athletes. What are the potential long-term side-effects of taking a ...
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79 views

Why do ion concentrations change with different secretion rates in pancreatic juice?

Why is it that when secretory rate increases in the pancreas the concentration of chloride ions decreases, and the concentration of bicarbonate increases in the production of isotonic NaCl secretion? ...
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37 views

Where can I find approximate rates of sequestration of CO2 for different species of algae?

For a study, I want to compare the rates of CO2 sequestration and fixation of a few different species of algae. I could not find any data on the sequestration rates. Any pointers to where I can find ...
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35 views

How are arms different than legs?

Ok, this is a bit of a tangent question, but it came up yesterday and I didn't know the answer: How are arms and legs defined physiologically? For example, we say humans have two arms and two legs, ...
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10 views

What biological processes are affected by dietary fiber besides peristalsis?

Dietary fiber affects the rate of peristalsis, but what other effects does it have? Does fiber affect signal transduction, hydration, the autonomic nervous system, organ function, other biological ...
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13 views

How Calcium regulated in myocardic AP and plateau phase?

The plateau phase is maintained by influx of calcium and outflux of potassium in the second stage: My conjuncture is that calcium transforms between two phases ionated phase (free calcium from ...
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24 views

Projection space of ML II channel in ECG

I am trying to find the approximate effective 3D region of the heart that is drawn from the ML II channel of the standard ECG either by using many channels or using one channel only (not possible ...
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37 views

Survival at high altitude

News reports state that MH370 flew at 45,000 feet for 23 minutes, and, assuming the cabin was no longer pressurized, that would have caused unconsciousness in the passengers. Based on this, what, if ...
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29 views

Few innervations to blood sugar regulation

Assume you have a case of young female where the intake of 75 grams of pure sugar leads to a rapid peak of blood glucose level (within seconds) plateau phase with very steady blood glucose level ...
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22 views

Prenatal hyperkinetic dysfunction and its effect on endurace

Do people with an hyperkinetic dysfuntion have a better endurance? Are they fitter in cause of their Dopamine-overdose or any other reason? I have a case, where someone does not do any sports, but ...
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14 views

To increase the stretchability of the ascending aortic arch

The thread about To decrease the amount of proteins in the lymphatic drainage for short term here raised this question. This paper discusses the stretch and Cauchy-stress properties of the heart. So ...
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26 views

Are there naturally occurring Biological Pacemakers?

There are artificial biological pacemakers which express funny channels. I am thinking if it is possible to have also naturally occurring (only in recovery cases and in silent tissues) biological ...
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10 views

Mechanisms to start simultaneous depolarisation of two Pacemakers?

I am thinking the biochemical mechanisms of the simultaneous depolarisations of two pacemakers. My intuition Funny channels (but not alone) No autonomic nervous system (my conjencture) What are ...
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15 views

What are the mechanisms of disabling extrinsic control of heart?

I started this thread by thinking this question but I developed it further below What is the mechanism maintaining refractory period of pacemakers? My conjuncture is that the mechanism is the ...
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22 views

Which reflex arcs work in Heart with extrasystoles?

I am researching what is triggering the extrasystoles - initial idea from this thread about Which ionic channels of Pacemakers can work in very low frequencies in extrasystole? I am interested in the ...
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14 views

Calling for Pressure pictures about Right and Left atrium

I am trying to understand the partially patent foramen ovale in patients with right-side heart failure. I am interested how the pressure in right and left atrium change in normal case in abnormal ...
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20 views

Laser surgery to stop damaged Sinus node from beating

I am trying to find any publication about laser surgery to stop the damaged sinus node which cannot anymore beat. I could only find publications which modifies SA node function. I am not sure if it ...
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21 views

How does vasomotor and bronchomotor reactions equilibrate local blood flow to correspond local ventilation?

I am trying to find some figure(s) to explain this. There is probably better name for "bronchomotor" reaction. They seem to opposite terms and actually affecting same things (alveolar diameter/tone); ...
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29 views

To define the total Resistance of Systemic Blood Circulation

Some systems are in parallel so let's just call those like $R_{\text{lungs}}$. I got this formula $$R_{\text{total}}=R_A+R_a+R_c+R_V+R_v$$ where $R_c$ capillaries, $R_a$ arterioles, $R_A$ Small ...
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54 views

Why is the resting membrane potential of cardiomyocyte more stable than that of Pacemaker in Phase 4?

There must be some channels that keeps this very stable. It seems to be that the resting membrane potential of pacemaker cells is steadily increasing until the threshold voltage. I think the same must ...
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12 views

To understand synthesis of e-NOS and n-NOS with respect to Ca and calmodulin

I found this sentence in my notes interesting E-NOS and n-NOS are Ca, calmoduline dependant ferments. They are synthesized from in small conc as response to physiological signals which ...
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31 views

To understand Nitric oxide, iNOS and Tumour cells

I have this figure about nitric oxide and tumor which is for schematic for me to understand it The figure should probably say that tumour cell is induced by NO or alone to go apoptosis and it ...
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0answers
17 views

What are the main parameters for systemic circulation?

I have in my notes that main parameters for systemic circulation are ejected blood per minute central venous pressure (in the right atrium) work done by the heart something else What can this ...
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40 views

ADH Synthesis in Supraoptic and Paraventricular Nuclei of the Hypothalamus

I have this sentence in my notes: Neurons paraventricularis and supraorbitus check the situation and secrete ADH in the nuclei, which by axonal transport → neurohypophysis, where storage take ...