Tagged Questions

The scientific study of short- and long-term changes in the size and age composition of populations and the processes driving these changes.

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4
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1answer
34 views

Drake's Law. What is the genome-wide mutation rate and what are the estimates?

Drake's rule Drake's rule states that the genome-wide mutation rate is more or less constant across all species — from E.coli to the house sparrow. Data From what I think being Drake's original ...
3
votes
0answers
36 views

How many pandas should exist?

I have a degree in Biology so I'm a little embarassed that I never learned this, but... How do we know 1600 Pandas isn't enough? I know that we have historical numbers (although I couldn't find ...
5
votes
0answers
36 views

How to define “Quasifixation” in continuous approximation of finite population?

Background Many models including the famous very first models derived by Sir Ronald Fisher in his early career, assume infinite population size. In an infinite population, an allele can rise in ...
5
votes
1answer
62 views

Can “human exclusion zones” in national parks for preserving Wolves and Grizzlies be a good idea?

There are National Preserves in the National Parks where some human activities are permitted. But can it make sense to create "exclusion zones" so no human would be permitted in a certain area, not ...
6
votes
1answer
91 views

Effects of selection on effective population size

Background The effective population size ($N_e$) is a central concept of evolutionary biology and is influenced by several parameters. For example: sex ratio bias affects $N_e$ $\left(N_e = ...
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0answers
33 views

Interpreting Graph

I am studying evolutionary biology, and been presented with this graph: I am having some difficulties understand its meaning. For a start, why is time measured as a fraction of the population size? ...
3
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0answers
58 views

Understanding the meaning of $s$ and $t$ in a population genetics equation

Sewall Wright in this article (1937) at the end of page 313 gives the equation: $$\Delta q = (s+tq)q(1-q) \space\space\space\space\space\space\space\space\space(1)$$ This equation is an ...
2
votes
0answers
34 views

What is the allelic frequency at mutation-selection-drift equilibrium?

mutation-selection equilibrium At mutation-selection equilibrium the expected frequency $f$ of a given locus is $$f ≈ \frac{\mu}{s\cdot h}$$ , where $\mu$ is the mutation rate, $s$ is the selection ...
15
votes
2answers
4k views

How many humans have been in my lineage? Is it almost the same for every human currently living?

If I were to count my father, my grandfather, my great-grandfather, and so on up till, say chimps, or the most common ancestor, or whatever that suits the more accurate answer, how many humans would ...
4
votes
1answer
38 views

Is there an association between environmental and mutational robustness?

The robustness of a genotype is the ability of this genotype to resist (always produce the same phenotype) to various parameters such as mutations and environment. The ability of a genotype to resist ...
7
votes
1answer
148 views

Fisher's Geometric Model for Dummies

Fisher's geometric model is still today one of the most important and fundamental model in evolutionary biology but it seems to me that most student in evolutionary biology don't really understand it ...
3
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0answers
48 views

How does Natural Selection Shapes Genetic Variation?

Background Importance of the additive genetic variance As stated here, the fundamental theorem of Natural Selection (NS) by Fisher says: The rate of increase in the mean fitness of any organism ...
6
votes
1answer
85 views

What does “Mutational Variance” mean?

Background The concept of mutational variance can be found in many articles including this one for example. The mutational variance of a trait number $i$ can be found in the M-matrix in position ...
4
votes
2answers
63 views

Premise of life cycle synchronization between predator and prey

While reading about the predator satiation hypothesis of the periodical cicadas' 13/17 year life cycles, I started wondering about its premise. By the way, I understand the math behind the prime ...
2
votes
2answers
53 views

Conservation Genetics - Book recommendations

Can you please give me some advice for a book in (evolutionary) conservation genetics that offers an in-depth review of the mathematical formulations used in this field. I read the book Evolutionary ...
4
votes
1answer
109 views

Start studying mathematical biology from basics

I am really passionate about theoretical and quantitative biology and I would like to build my future career around this topic. I've just got my bachelor's degree in biology (ecology) but scince I've ...
-1
votes
1answer
86 views

What is the outcome of a human population starting with only 2 individuals? [closed]

Starting with a human population N = 2, is there any way the genetic variability seen today could have come about? I don't know that much about meiosis, but isn't there a very limited number of ...
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vote
0answers
29 views

Effects on Bear Population [closed]

imagine in a given area or an ecosystem ,bear hunting is totally banned, but there is a scarcity of food for the bears. i want know what would be the future of the bear population?. and want to derive ...
1
vote
1answer
60 views

Does a top heavy population grow, decline or stabilize?

Imagine a population that has a larger proportion of older individuals than younger ones, what could possible happen to it in the future? I am guessing that if the older individuals reproduce, the ...
2
votes
1answer
44 views

$F_{ST}$ when considering a multi-allelic locus

Sewall Wright defined the $F_{ST}$ in a metapopulation as being: $$F_{ST} = \frac{\text{Var}(p)}{\bar p (1-\bar p)}$$ , where $p$ is a vector of frequencies of a given allele and $\bar p$ and ...
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0answers
43 views

$F_{ST}$ and the genetic variance in metapopulations

From this video (21'15''), the speaker gives the following formulae in order to calculate the between and among populations genetic variance from the $F_{ST}$: $$V_{Among Pop} = 2 F_{ST}V_G$$ ...
1
vote
1answer
53 views

Various Genetic Loads and their Definitions

In population genetics, we talk about several types of genetic loads (also called just loads). I am asking for a exhaustive list and a short definition. Here are for example some genetic loads that ...
1
vote
1answer
77 views

Coalescent theory - independence of coalescent times

Let $T_i$ be the time to coalesce from $n(t)=i+1$ to $n(t)=i$, where $n(t)$ is the number of sites that have not coalesced yet. In the below example the maximum $n(0)=6$. As I understand it, many ...
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0answers
40 views

Inbreeding depression and dominance

From this article, second paragraph of the second page A classic theoretical result is that the mean of a character controlled by a single locus $i$ with two alleles $A_{i1}$ and $A_{i2}$ is only ...
2
votes
1answer
54 views

Coefficient of relationship and path of coefficient

A path of coefficient of relationship is defined as $$\rho_{AO} = \left( \frac{1}{2}\right)^n \sqrt { \frac{1+f_A}{1+f_O}}$$ This SE post discusses this definition From this, the coefficient of ...
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0answers
45 views

How important is the womb's environment?

- Background - Talking about one phenotypic trait, the total phenotypic variance $V_p$ is decomposed into genetic and environmental variance for this trait, represented by the symbols $V_G$ and $V_E$ ...
2
votes
0answers
44 views

Inbreeding Coefficient and Coefficient of Relationship

Wikipedia gives the following formula to calculate a "path of coefficient of relationship" between an ancestor $A$ and an offspring $O$: $$\rho_{AO} = 2^{-n} \left( \frac{1+f_A}{1+f_O} \right)^{1/2} ...
0
votes
1answer
57 views

Defining: Evolutionary (quantitative) Genetics and Population Genetics

How do we define the fields that are Evolutionary (quantitative) genetics and population genetics. What set these two fields apart? Can you try to provide definitions? To my intuitive understanding, ...
0
votes
1answer
35 views

Metapopulation structure - book recommendations

What book would you recommend me to study: the dynamics of metapopulations, the structure of metapopulations, the evolution in structured metapopulations? I am not looking for an introduction ...
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0answers
64 views

Effects of Genetic Drift on Linkage Disequilibrium

From what I understood of @Canadianer's answer here... Genetic drift randomly causes negative or positive linkage disequilibria, by changing allele frequencies through random sampling. Natural ...
2
votes
1answer
40 views

Definition of Linkage Desiquilibrium (LD)

According to wiki, linkage disequilibrium $D$ equals $$D = x_{11} - p_1\cdot q_1$$ where: $$ \begin{matrix} \text{Haplotype} & \text{Frequency}\\ A_1B_1 & x_{11}\\ ...
1
vote
1answer
134 views

Heterozygosity and overdominance

Consider $m$ loci with heterozygote advantage (overdominance) such that the fitness of the two homozygotes is $1-\frac{s}{2}$ and the fitness of the heterozygotes is $1+\frac{s}{2}$, where $s>0$. ...
1
vote
1answer
33 views

Coalescent Theory - Probability for $k$ alleles that of one coalescence event occured $t+1$ generations ago

From this textbook Under the wright-Fisher model of genetic drift and under the assumption that all alleles are neutral, the probability that $k$ alleles had $k$ distinct parent alleles the previous ...
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vote
2answers
90 views

Effect on fitness of mutations

What is the distribution/probability density function (PDF) of impacts on fitness of new mutations? I very welcome any partial answer that does not give the whole PDF but just some information ...
1
vote
1answer
38 views

Dominance/recessivity of new mutations

What is the distribution/probability density function (PDF) of recessivity/dominance of new mutations? I very welcome any partial answer that does not give the whole PDF but just some information ...
1
vote
1answer
59 views

Additive genetic variance with $n$ loci

The genetic variance of a quantitative trait (the quantitative trait in question is fitness) can be express as the sum of two components, the dominance and additive variance: $$\sigma_D^2 + ...
1
vote
1answer
92 views

Additive genetic variance with $n$ alleles

The genetic variance of a quantitative trait (the quantitative trait in question is fitness) can be express as the sum of two components, the dominance and additive variance: $$\sigma_D^2 + ...
3
votes
2answers
472 views

Initial population when i count backwards?

My question is dealing with how many ancestors it took to produce me: --> to produce me it took 2 people (my parents) = ($2^1$) people = 2 --> one generation further included = ($2^1 + 2^2$) people ...
4
votes
1answer
115 views

How to calculate the effective population size ($N_e$) with overlapping generations?

From this Source: If generations are overlapping, then the effective population size $N_e$ does not equal the population size $N$. I know mathematical formulations in order to find the effective ...
2
votes
1answer
55 views

Effective population size when the population sizes varies from season to season

Let's think of a species which has four generations per year and which population size changes from season to season so that the population size is 100 in summer, 200 in spring, 50 in autumn and 20 in ...
5
votes
2answers
69 views

Linkage disequilibrium with multiple alleles and loci

Linkage disequilibrium $\left(D\right)$ for two bi-allelic loci is defined as: $$D=X_{11}X_{22} - X_{12}X_{21}$$ where $X_{11},\ X_{12},\ X_{21},\ X_{22}$ are the frequencies of the haplotypes ...
7
votes
1answer
87 views

Selection on linked loci in a diploid population

Let’s consider two linked loci $A$ and $B$ that are both bi-allelic. In consequence, we have four different possible haplotypes $A_1B_1$, $A_1B_2$, $A_2B_1$, $A_2B_2$, which frequencies are $X_1$, ...
7
votes
4answers
327 views

What prevents predator overpopulation?

I've often heard that a population, human or otherwise, will continue to grow as long as there is food available (assuming nothing else is killing them off). It makes sense: if you have food you can ...
1
vote
1answer
65 views

Why will world population keep growing if all women have only 2.1 children

Why is it that, even if we were going to immediately agree that every women will not have more than 2.1 children on average, the world population would continue to grow for another 60 years? I've ...
6
votes
1answer
97 views

Hill-Roberston effects and effective population size

From this article, first page, middle of the second column: Even if harmful alleles do not become fixed, they can still reduce the efficacy of selection on neighbouring loci through a process ...
3
votes
1answer
76 views

Chaos theory and population cycles

I have just begun to read about Chaos theory and have come across the statement that "Period three implies chaos." My question: Does any odd period imply chaos or only 3? If so, how can populations ...
2
votes
1answer
184 views

Why do genetic drift generates negative linkage disequilibrium?

The very first sentence of the abstract of this article are: "In finite populations subject to selection, genetic drift generates negative linkage disequilibrium, on average, even if selection ...
7
votes
2answers
148 views

The Assumption of Weak Selection?

I was reading this question and I failed to fully understand the introductory part of it. The OP (@Artem Kaznatcheev) says: Most analytic models like to assume weak selection because it allows ...
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vote
0answers
54 views

Why did the yeast rise?

Here are the notes I made for an experiment I was doing (I didn't put it here as it is too long) (please ignore the numbers at the end of the pdf file) The graph looks like this: As you see on ...
2
votes
1answer
215 views

Population Growth Rate Question?

A population of 600 birds faced a problem of biological magnification resulting in a large number of deaths reducing their population to 350. But 230 births also took place and 21 birds immigrated ...