4
votes
1answer
111 views

How do I calculate the change in allele frequency in a haploid population under selection?

From this book For simplicity, let us consider a haploid organism and assume that the frequencies of alleles $A_1$ and $A_2$ are given by $x$ and $y=1-x$, respectively. We also assume that the ...
6
votes
1answer
69 views

Hill-Roberston effects and effective population size

From this article, first page, middle of the second column: Even if harmful alleles do not become fixed, they can still reduce the efficacy of selection on neighbouring loci through a process ...
17
votes
2answers
345 views

Smallest viable reproducing population

What is the smallest viable reproducing population, such as in a human population. By viable I mean a population which keeps genetic defects low (enough). A very strongly related question: what is ...