Short Background In infinite population, the frequency of a given allele at time $t$ given that it started at time $t_0$ at frequency 1/N is given by iterating (or by the general solution which can ...
from this article, first page, middle of the second column: Even if harmful alleles do not become fixed, they can still reduce the efficacy of selection on neighbouring loci through a process ...
What is the smallest viable reproducing population, such as in a human population. By viable I mean a population which keeps genetic defects low (enough). A very strongly related question: what is ...