# Tagged Questions

The scientific study of short- and long-term changes in the size and age composition of populations and the processes driving these changes.

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### How to define “Quasifixation” in continuous approximation of finite population?

Background Many models including the famous very first models derived by Sir Ronald Fisher in his early career, assume infinite population size. In an infinite population, an allele can rise in ...
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### Variance in Fst in the infinite island model

The most famous result in the study of structured populations come from Sewall Wright. He showed that in an island model, where each subpopulation is of size $N$ and the migration rate is $m$, then ...
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### How to calculate the number of sterile insects that must be released in SIT?

The sterile insect technique (SIT) is used to control insect pests through overwhelming the population in sterile males. The increase in sterile males released into an environment causes the increase ...
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### Mutation-Selection-Drift Equilibrium

mutation-selection-drift equilibrium is one of the most important concept of population genetics. I could easily find the calculations for mutation-secltion equilibrium and for mutation-drift ...
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### Is $F_{ST}$ a probability and a correlation coefficient?

$F_{ST}$ is one of the most famous and most important statistics of all of evolutionary biology. Yet, many people misunderstand it or misuse the classical results from the literature on $F_{ST}$ (...
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### Understanding the meaning of $s$ and $t$ in a population genetics equation

Sewall Wright in this article (1937) at the end of page 313 gives the equation: $$\Delta q = (s+tq)q(1-q) \space\space\space\space\space\space\space\space\space(1)$$ This equation is an ...
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### Population size and genetic drift - What are the evidences?

Wright-Fisher model From the Wright-Fisher model of genetic drift, the random sampling of allele from one generation to the next is taken from a binomial distribution with parameters $2N$ and $p$, ...
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### Analytical Methods for Estimating Probability of Fixation

The probability of fixation $P$ of an allele is an very important measure and there exists several solutions to estimate this probability. Each method has its own assumptions and it is often hard to ...
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### What is the probability of fixation for a mutant under fluctuating selection?

Here is an answer which explain how one can model the frequency of an allele that is under fluctuating selection (selection that varies through time). Not, thinking about fluctuating selection, there ...
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### How does the population fitness changes after a change in mutation rate

The mean population fitness as given by mutation load theory depends only on the genome-wide mutation rate ($U$). My question is: how many generations is needed to reach a new mutation load ...
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### Monod Kinetics--Growth of E.Coli in a Bioreactor

I am doing a study for a lab class. We are growing E. Coli in a bioreactor. We want to vary the volume of the initial biophase which we add after the substrate has been brought to 37 degrees C. My ...
- Background - Talking about one phenotypic trait, the total phenotypic variance $V_p$ is decomposed into genetic and environmental variance for this trait, represented by the symbols $V_G$ and $V_E$ ...