Does the NMDA antagonist, Memantine that's used to prevent excitotoxicity in Alzheimer's disease (AD) and Dementia with Lewy Bodies (DLB) cause brain damage? I know that in rodents NMDA antagonists ...
Which classes of drugs (filed by their binding sites) induce a release of $\beta$-endorphin? I know of agonists of the nAChRs and 5-HT1A and ethanol. Are there any others? Please cite journal ...
I know that 5-HT2A partial agonism is the key mechanism of action of serotonergic psychedelics but I also know that some research (e.g. the selective (no activity on any other known receptor sites) ...
What effect do SSRIs have on the expression of the ligand-gated ion channel, the 5-HT3 receptor?
Loperamide is frequently used to slow gastrointestinal motility. It is available over the counter (in the US, I don't know about elsewhere) without any regulations whatsoever, yet it's derived from ...