A receptor is a molecular target for a chemical signal such as a neurotransmitter, hormone or drug. Binding of the signal to the receptor initiates or modulates behaviour in the receiving cell.
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Which Receptors are Involved in the antidepressant effects of SSRIs?
From what I've read the major receptor subtypes involved in the antidepressant effects of SSRIs are:
5-HT1A
5-HT2C
5-HT3
5-HT6
Please cite journal articles to back up your claims, I don't want any ...
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Are all Autoreceptors Downregulated by their Respective Endogenous Ligands?
I know that the 5-HT1A and $\alpha$2 adrenoreceptors receptors serve as autoreceptors for serotonin (5-HT) and norepinephrine respectively and are down-regulated by repeat exposure to their respective ...
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Do SSRIs downregulate or upregulate the 5-HT3 receptor?
What effect do SSRIs have on the expression of the ligand-gated ion channel, the 5-HT3 receptor?
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If a receptor is inhibited throughout embryogenesis, could there be observable phenotypic differences in the adult?
So I read a journal article entitled "Maternal hypoxia and caffeine exposure depress fetal CV function during primary organogenesis" (Momoi, et al., 2012) and in essence the article speaks of the ...
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Molecular cause of cramps, spasms and strengthening in muscles? (incl. intro to muscle contraction)
When motor neurons are stimulated to trigger an action potential, this potential propagates down the spine, eventually reaching a neuromuscular junction, causing the release of acetylcholine (ACh).
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Which classes of drugs (filed by their pharmacology) induce a release of beta-endorphin?
Which classes of drugs (filed by their binding sites) induce a release of $\beta$-endorphin? I know of agonists of the nAChRs and 5-HT1A and ethanol. Are there any others?
Please cite journal ...
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Which Receptors are involved in Psychedelia/Psychosis?
Which receptors are involved in Psychedelia/Psychosis? I know that the 5-HT2A, 5-HT3, D2, κ-opioid and NMDA receptors are likely involved in psychosis.
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Does regulate always mean suppress when it comes to heteroreceptors?
Do heteroreceptors always suppress the release of the neurotransmitter they regulate upon their (the heteroreceptor's) activation?
