A receptor is a molecular target for a chemical signal such as a neurotransmitter, hormone, or drug. Binding of the signal to the receptor initiates or modulates behaviour in the receiving cell.

learn more… | top users | synonyms

2
votes
1answer
68 views

The mechanism of mechanoreception?

I am interested in knowing the molecular mechanism behind mechanoreception/mechanotransduction (i.e. mechanism behind receptor potential generation on mechanical stimulation). I know that most ...
3
votes
0answers
37 views

Are all Autoreceptors Downregulated by their Respective Endogenous Ligands?

I know that the 5-HT1A and $\alpha$2 adrenoreceptors receptors serve as autoreceptors for serotonin (5-HT) and norepinephrine respectively and are down-regulated by repeat exposure to their respective ...
2
votes
0answers
73 views

Do SSRIs downregulate or upregulate the 5-HT3 receptor?

What effect do SSRIs have on the expression of the ligand-gated ion channel, the 5-HT3 receptor?
1
vote
0answers
32 views

If a receptor is inhibited throughout embryogenesis, could there be observable phenotypic differences in the adult?

So I read a journal article entitled "Maternal hypoxia and caffeine exposure depress fetal CV function during primary organogenesis" (Momoi, et al., 2012) and in essence the article speaks of the ...
1
vote
0answers
15 views

Which classes of drugs (filed by their pharmacology) induce a release of beta-endorphin?

Which classes of drugs (filed by their binding sites) induce a release of $\beta$-endorphin? I know of agonists of the nAChRs and 5-HT1A and ethanol. Are there any others? Please cite journal ...
1
vote
0answers
19 views

Which Receptors are involved in Psychedelia/Psychosis?

Which receptors are involved in Psychedelia/Psychosis? I know that the 5-HT2A, 5-HT3, D2, κ-opioid and NMDA receptors are likely involved in psychosis.
1
vote
0answers
23 views

Does regulate always mean suppress when it comes to heteroreceptors?

Do heteroreceptors always suppress the release of the neurotransmitter they regulate upon their (the heteroreceptor's) activation?