Tagged Questions
3
votes
1answer
44 views
How are atoms in benzopyridines and benzopurines numbered?
I am well-aware of the numbering system used for the traditional bases, as seen below.
My question is how are the atoms in the size-expanded bases seen in xDNA and xRNA numbered?
2
votes
2answers
115 views
Translate DNA to Protein
Assuming the sequence shown is read left to right, what is the sequence of the protein produced?
sequence: 5’-ATGTACTTCCATCTGGAATAG-3’
MY ATTEMPT: I know RNA is synthesized 5 to 3. This is ...
11
votes
1answer
126 views
Can DNA act as a translation substrate?
I get conflicting answers. One would think if it was true, it would be rather seminal and widely known.
There are papers from Khorana[1], Holland[2], and Bretscher[3] (late 60s) that suggest that it ...
5
votes
2answers
421 views
Why do DNA and RNA have the functions they have?
I know that there are two most important directions of genetic information transfer in living organisms: DNA->DNA and DNA->RNA. The first is replication, and the second is transcription. I wonder if ...
22
votes
3answers
2k views
Why do eukaryotic organisms have introns in their DNA?
We touched on introns and exons in my bio class, but unfortunately we didn't really talk about why Eukaryotes have introns. It would seem they would have to have some purpose since prokaryotes do not ...
14
votes
2answers
176 views
Can methylation from DNA get copied to RNA during transcription?
Methylation on gene-body and 3'UTRs if copied to mRNA can potentially regulate post-transcription modifications or expression regulation. But I'm not sure if they are maintained after transcription or ...
10
votes
2answers
137 views
Can DNA produce ribozyme-like structures?
RNA is known to act as an enzyme via its ability to fold itself in specific ways.
Is DNA capable of such structures? Or is it some biochemical reason stopping the folding?
Have they been observed in ...
10
votes
3answers
433 views
What implications has the missing 2'-OH on the capability of DNA to form 3D structures?
The chemical difference between RNA and DNA is the missing 2'-hydroxyl group in the nucleotides that build DNA. The major effect of that change that I know of is the higher stability of DNA compared ...
33
votes
3answers
7k views
Why is uracil used in RNA rather than thymine?
What is the advantage gained by the substitution of thymine with uracil? I have read previously that it is due to thymine being "better protected" and therefore more suited to the storage role of ...
