The process of biological aging or the state of an organism being biologically old.

learn more… | top users | synonyms (2)

-1
votes
0answers
22 views

Why haven't humans 'evolved away' aging? [duplicate]

Here's a weird question: why haven't we evolved to live longer, as opposed to living longer through healthcare etc.? It makes sense that if a person lives longer, they have more offspring, ergo in the ...
2
votes
1answer
23 views

Do Blanding's Turtles die of old age?

I have recently found articles and various claims that turtles (Blanding's turtles as an exact example) could possibly live indefinitely. http://discovermagazine.com/2002/jun/featturtle This is said ...
6
votes
2answers
77 views

Can plants live forever? [duplicate]

I know that some plants die for old age like a lettuce. But there are trees like Baobabs or larger Ficus in the tropics of whom we don't know their age. And trees like spruce reaching 9950 years old, ...
2
votes
0answers
19 views

What is the role of RAGEs?

According to articles I read, AGEs (advanced glycation end products) activate RAGEs (receptors for AGEs). This activation increases the ROS (reactive oxygen species) levels in the cells. 2003 - ...
22
votes
2answers
3k views

Do all organisms have to die?

I understand (a little) that there are biological clocks and reason that after a certain amount of time organisms die. I'm wondering if that is something inherent in our DNA or in biology/chemistry in ...
2
votes
1answer
32 views

About modern dating techniques

In a comment to this question, it was said that Radiocarbon dating won't work. For a start the tree needs to be dead, which since you're not using the rings I'm assuming it isn't. Also the atomic ...
9
votes
2answers
83 views

How well does the radius of a tree correlate with its age?

I'm looking for a cheap non-invasive ways to approximate the age of a tree (a birch). Measuring the radius pops up in the mind as the first alternative. How would one do that? Measure at multiple ...
3
votes
1answer
69 views

What are senescent cells doing in our bodies? [closed]

I'm reading a paper that mentioned the elimination of senescent cells delays aging. I'd like to receive more information about it. The Baker study published in Nature demonstrates that targeted ...
10
votes
1answer
632 views

Have there been studies done to test Immortality of cancer cells in culture?

This website on cultured cancer cells () says cancer cells may be immortal. I am wondering if there has been any research done to find if cancer cells are really immortal. How old is the still ...
0
votes
0answers
61 views

Known ways to modify the genetic structure of the 13 loci used in CODIS

After reading the answer to Does our DNA change during our lives?, I was wondering if and how it would be possible to change the structure of the 13 loci that are used in the CODIS database, in such a ...
5
votes
1answer
61 views

Do people grow shorter as they age, how common is it, and what triggers it?

Is it true that people become gradually shorter as they age? If it is, is it more common in one gender than the other? And is it known what triggers this? (Considering that the "shortening" probably ...
4
votes
1answer
103 views

Circulating factors affecting human health/longevity

Circulating factors present in young mice have been shown to promote rejuvenation of aged mice, suggesting that tissues have inherent capabilities to regenerate, and circulating factors may be ...
7
votes
2answers
1k views

Can human organs be transplanted indefinitely?

I watched this movie, where they rented hearts to people for a year. I wonder if it is possible to transplant a heart indefinitely from person to person, or does the heart have a lifetime? So, do ...
4
votes
2answers
287 views

What determines the autumn leaf color?

It is autumn out there. Green, brown, red, yellow, and mixed-colored leaves drop from the trees to the ground. What determines the colors of the leaves? Wikipedia tells me Leaf senescence is the ...
2
votes
2answers
132 views

Do couples having children later in life act as an evolutionary mechanism?

Ok, this may be just wild nonsense and I have to warn that my knowledge on the subject is limited. I was reading about how in some countries people choose to have children later in life. After that ...
64
votes
1answer
6k views

Do bacteria die of old age?

I know that the cells of mammals at least stop dividing when they are old, and then die a programmed cell death. Then other cells have to replace them. But in a bacterial colony, each cell ...
3
votes
2answers
354 views

In practice, do fishes die from old age?

I was watching sea birds eating fishes and wondered if fishes actually died from old age, or if they are all eaten before this can happen? I reckon some big predator fishes must be able to live long ...
2
votes
1answer
127 views

Senescence, immortality and evolution?

Many have heard about the fabled "immortal" jellyfish, Turritopsis dohrnii, which doesn't die from aging (senescence) and can revert the aging process indefinitely. It is rather remarkable that only ...
2
votes
0answers
28 views

How can stem cells be counted in body?

In the study of supercentenarian woman here, it was found that all her blood cells are formed from only two stem cells (ancestor stem cells). How scientists can distinguish cell ancestors? Aren't ...
31
votes
7answers
5k views

Why does evolution not make our life longer?

Why does evolution not make life longer for humans or any other species?
4
votes
2answers
156 views

Does increased physical activity increase the rate of cell division?

Ever since learning that the shortening of telomeres is linked to aging I've tried to figure out what causes cells to divide, and if it's possible to slow down the rate of cell division through life ...
2
votes
0answers
34 views

Source of information on the evolution of aging/senescence

Do you know a good review (published peer-reviewed or an online course or whatever) that offers a good overview of all hypothesis explaining the various patterns linked with aging? I'd like this ...
6
votes
0answers
45 views

Effect of Aging on SA node's sympathetic fibers

I am trying to understand the effect of aging on the sympathetic fibers of SA node. I know that aging shifts the vagal curve to left in frequency due to aging. However, I am interested if aging has ...
1
vote
0answers
68 views

What is the name of systemic tension of muscles?

I meat a overtrained friend (25 years old) who cannot rest. He has all muscles and most of the skin very tense. He is practising regularly in gym and sleep badly. He moves like a stick figure and has ...
3
votes
1answer
85 views

Do people with gout live longer?

Antioxidants reduce damage to tissue (by scavenging the free radicals) and thus may reduce ageing.It is known that Uric acid is a very good antioxidant. People with gout have excess accumulation of ...
1
vote
2answers
70 views

In what ways can mechanisms of apoptosis be damaged?

How many ways can an Apoptosis mechanism be made disfunctional or irreparably damaged? If a cell has damaged Apoptosis mechanisms and it divides will its daughter cells have such damage?
1
vote
3answers
81 views

Does DNA influence death (e.g. by cell aging)

I know that we age because of errors in the cell replication process and these errors eventually leads to death. If we exclude environmental factors, are there any other factors that can cause these ...
0
votes
1answer
63 views

Fibrinous inflammation, exudate and scarring in monotonous movements and ageing

I have palpated many hard organs during my work and studies. I have seen many young and old people who have hard organs, like very hard shoulder - very common. I have interviewed some of them, some ...
2
votes
2answers
123 views

How does the telomere repeat sequence vary in Eukaryotes?

Question: How does the telomeric repeating sequence vary in non-vertebrate Eukaryotes? If you know the repeating sequence of a given species I would appreciate hearing it. Background: Telomerase is ...
3
votes
1answer
51 views

How do mosquitoes maintain telomere length?

While the vast majority of eukaryotic organisms maintain their chromosome ends (telomeres) via telomerase, an enzyme system that generates short, tandem repeats on the ends of chromosomes, other ...
0
votes
0answers
37 views

Can we define biological age? [duplicate]

How can we define ageing from a biological standpoint without making an appeal to chronological age? Related, but less important, are there any metrics we can use to determine someone's biological ...
0
votes
1answer
41 views

How does the body repair extracellular damage caused by glucose?

So we know that glucose is an aldehyde that can cause cell damage to the lysine and arginine residues on proteins through the Maillard Reaction (among other damaging reactions that glucose ...
4
votes
2answers
157 views

Is solving cancer required in order to avoid aging?

When the telomerase enzyme is not active the telomere shortens every time the cell duplicates leading to a reproductive limit (Hayflicks limit). On one hand this is a believed reason for aging. On the ...
3
votes
2answers
2k views

Cell life: division for immortality or reproduction with aging

Are the two cells that are derived from one cell, ‘twin sisters’ or a ‘mother and a daughter’? In other words, can a cell really be divided to live an "immortal" life or is cell reproduction the ...
4
votes
1answer
362 views

How much does the Hayflick limit/telomere length vary across taxa and within humans?

Since they seem to be quite connected, I'm curious if anyone knows of research comparing the Hayflick limit (and presumably by extension telomere length) between different taxa. I've heard the ...
6
votes
1answer
68 views

How well supported is the hypothesis that aging is mainly caused by the number of mutations in tissues?

I heard the hypothesis, that the (main) reason of aging is the increasing number of mutations in body tissues. The higher the number of mutations is, the older tissue is. Is this true? And how well ...
0
votes
2answers
181 views

How is it that the WI-38 cell line isolated by Hayflick in 1962 is still very much around and not affected by the 'Hayflick Limit'?

I have searched the net and I have not been able to come up with an clear answer. Edit: Here is the para quoted from Nature http://www.nature.com/news/medical-research-cell-division-1.13273 "So began ...
3
votes
1answer
101 views

Hibernation, Metabolism and Aging

People are beginning to seriously research space travel applications of therapeutic hypothermia, specifically for reducing metabolism and stress on humans traveling to Mars. It seems that as you ...
2
votes
1answer
66 views

Telomere elongation methods?

What sort of telomere elongation methods are there currently? Would this stop aging? (edit: No, probably) I couldn't turn up anything good on google. I was thinking that maybe you could sequence ...
7
votes
2answers
442 views

Do immortal organisms exist?

Do organisms exist that are able to live indefinitely if they are not killed by external factors? Under external factors I would consider things like predators and natural disaster but not illness by ...
9
votes
1answer
202 views

How are new people created from the DNA of an aged person. i.e. Why are we young?

The question "why do we age" has been asked numerous times. But why are we young? The cells of the adult human being are an age (time>0), but how can old cells create new cells that are younger than ...
6
votes
1answer
692 views

Exercise causes number of cell divisions to approach Hayflick limit faster? And hence shorten life expectancy?

A world class athlete spends a lot of time performing intense exercises. Correct me if I'm wrong, but I assume that these intense exercises causes significant damage to the athlete's cells, but with ...
7
votes
3answers
883 views

Is there any kind of immortality in plants?

I asked a question about immortality of hydra and learned good things about senescence. Now I would like to know about immortality in plants, if there is some kind of immortality in plants and how ...
16
votes
4answers
3k views

Why is the Hydra Biologically Immortal?

I have heard that the Hydra organism is biologically immortal (later I found that there are more immortal organisms). Now I know that its immortality is related to its telomerase. The thing is that we ...
3
votes
0answers
84 views

Papers linking telomeres and aging [closed]

I'm currently writing a piece of work about telomeres and aging, and wondered if you could share some good papers you've either read or know of.
4
votes
1answer
123 views

Difference In Telomeres Between A Thale Cress Plant And A Methuselah Tree

From what I have read and understood telomeres cap off how many times a cell can divide before it can no longer divide and that is what causes aging. A thale cress plant apparently has a life cycle ...
8
votes
1answer
9k views

Do crocodiles age?

I was watching a talk by Michio Kaku and he mentioned that crocodiles (or possibly alligators, I forget offhand) don't actually age -- they can die, but they essentially go through no aging process ...
3
votes
2answers
251 views

Does the speed of electrical impulses through neurones decrease with age?

From what I read on the NatGeo app, it stated that the speed of the electrical impulses that are sent by a neurone will be approximately 332 kilometers per hour. Will the speed of this electrical ...
5
votes
1answer
224 views

What evolutionary pressures pushed Galápagos tortoises to mature so slowly and live so long?

I read that they take up to 40 years (in the wild) to reach the age of reproduction and are thought to live over 100 years, with one in captivity reaching over 170 years. Can someone explain in ...
6
votes
3answers
178 views

What reasons allow for women to outlive men?

It is a well-known fact that women tend to outlive men. I often hear people unscientifically stating that men generally generally die younger because of the higher stress encountered in their work ...