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3
votes
0answers
20 views

To measure Na/K channel activation in membrane level?

Assume that there are two different signals going on in the ECG - during depolarisation and repolarisation in the standard ECG. I got an advice that do not use the standard ECG in measuring exactly ...
4
votes
4answers
168 views

Specificity of Protein Kinases in Signaling Pathways..?

In most of the signaling pathways the activated receptor when activates Protein Kinase through the action of secondary messenger, then these protein kinases almost always phosphorylate on the specific ...
2
votes
2answers
72 views

Resting and action membrane potential..?

In the resting membrane potential of neurons the inside of membrane is kept negative and outside of membrane is kept positive by the utilization of energy through Na-K Atpase pump, While during action ...
2
votes
1answer
113 views

How do TLR1/TLR2 activate the MyD88 dependent pathway

Recently, I've been reading about the MyD88 dependent signalling pathway, with particular reference to its activation in Macrophages and other cells of the immune system on recognition of a pathogen. ...
0
votes
2answers
27 views

To understand Second messenger signalling in I/c and E/c

I found this picture in my study materials. I think it is too schematic and ignores the big pictures. I think the thing connected to the hormone is receptor. The second messanger is then connected ...