The snp tag has no wiki summary.
4
votes
3answers
46 views
Is there any source for raw data of SNP genotype frequency?
On sites like SNPedia, some pages contain the frequency of the SNP in question in different populations, based on published research. I'm trying to write a script that takes 23andme data and compares ...
1
vote
1answer
39 views
Mapping a mutation to known SNP, 3' UTR, miR
I've parsed out a very large TCGA cancer ssm (single mutation file) file to give me the essential information.
The ssm is in the following format:
...
1
vote
1answer
67 views
Why is Sanger sequencing inferior for detecting SNPs in cancer cells?
I am familiar with Sanger sequencing, but at the level of an undergraduate. A lecturer of mine tried to describe Sanger sequencing as losing the sequence information in noise when used to detect ...
0
votes
1answer
30 views
SNPs mapping into protein
Starting a new project on protein-protein interactions and SNP analysis tool development. I would like to ask how does SNPs is mapped into protein? What does mapping means?
3
votes
1answer
45 views
Understanding these SNP annotations
I am looking at the PharmaPGKB database for SNPs and trying to understand what the following annotation means:
rs1801131 at 1:11854475 in CLCN6, MTHFR (VIP)
Ok, ...
1
vote
1answer
45 views
Interpreting SNP-in-gene associations from GWAS studies
For most SNPs identified in GWAS studies, is the underlying assumption that if it is indeed associated with a phenotype (and lets assume its associated because it affects protein function), that you ...
2
votes
1answer
49 views
variation in expression accounted for a SNP — what's a usual percent?
I am reading a GWAS paper that found a SNP associated to predisposition to colon cancer and was assessed for gene expression of the nearby gene. They found that the genotype accounted for 55% of the ...
