Single nucleotide polymorphisms, or SNPs, are differences between two sequences of DNA at one individual nucleotide location.

learn more… | top users | synonyms

1
vote
0answers
25 views

Regarding the NCBI FTP site

I am trying to extract information about SNP data from the FTP server of NCBI. Could someone please explain to me how the directory is organised? There are many many files and folders and I can't ...
1
vote
0answers
29 views

Comparing SIFT and PolyPhen to other methods

I'm looking for a database of nsSNP (non synonymous single nucleotide polymorphisms) and their effects. As I understand, the common methods to predict this are SIFT and PolyPhen, and I want to compare ...
1
vote
0answers
27 views

Genetic variation in humans and model organisms (measured by SNPs)

I was wondering what is the range of SNP density across species and model organisms. I.e., what would be a reasonable estimate for the SNP density (i.e., x SNPs for each 1 Kb) in: humans humans ...