The snp tag has no wiki summary.
3
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1answer
37 views
Understanding these SNP annotations
I am looking at the PharmaPGKB database for SNPs and trying to understand what the following annotation means:
rs1801131 at 1:11854475 in CLCN6, MTHFR (VIP)
Ok, ...
2
votes
1answer
49 views
variation in expression accounted for a SNP — what's a usual percent?
I am reading a GWAS paper that found a SNP associated to predisposition to colon cancer and was assessed for gene expression of the nearby gene. They found that the genotype accounted for 55% of the ...
1
vote
1answer
49 views
Why is Sanger sequencing inferior for detecting SNPs in cancer cells?
I am familiar with Sanger sequencing, but at the level of an undergraduate. A lecturer of mine tried to describe Sanger sequencing as losing the sequence information in noise when used to detect ...
1
vote
1answer
40 views
Interpreting SNP-in-gene associations from GWAS studies
For most SNPs identified in GWAS studies, is the underlying assumption that if it is indeed associated with a phenotype (and lets assume its associated because it affects protein function), that you ...
0
votes
1answer
27 views
SNPs mapping into protein
Starting a new project on protein-protein interactions and SNP analysis tool development. I would like to ask how does SNPs is mapped into protein? What does mapping means?
