Splicing is a modification of an RNA after transcription, in which intervening nucleotide sequence sequences (introns) are removed and the remaining sequences (exons) are joined.

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How to predict the effect of a non coding SNP variant on the expressed protein?

I am writing a paper for non coding SNPs on patients with metastatic breast cancer. Having used a specific gene panel (NGS) of approximately 60 genes, I'm currently running out of ideas on what to ...
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Extracting the donor/acceptor sites from mRNA sequence(PERL/ DNA transcription)?

I have the following program that I am analyzing and trying to understand. Overall purpose of it is to put out, based on the option selected, the set of introns, exons, acceptor sites , or donor sites ...
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Predicting alternative transcript sequence and probability from a single SNV

I am currently studying a small number of non coding SNPs in terms of their contribution to the cancer phenotype. All are obtained from massive parallel sequencing on a specific gene panel, utilizing ...
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Splicosomes, Transesterification

How is it that a spliceosome complex ensures that the 5' end of the cut intron will attack the branching point on the same intron but not the branching point of the next intron? And some introns are ...