Tagged Questions

Cells which have not fully differentiated yet, i.e. with the potential to develop into other kinds of cells through asymmetric cell division.

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What would a human body do with an excess of stem cells? [closed]

This question STEMS (WOO starting right off with the puns) from an lack of understanding of stem cells. My naivety tells me that when a stem cell is introduced to the body, "SOMETHING" tells that cell ...
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book on stem cells

Could someone advise a good book on stem cells? I know almost nothing about them, but have a good background in biochemistry. Want to know where did they located in the body (the niche). How did they ...
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How to make sure a stem cell culture is cancer free?

Say I take a blood sample from an adult, extract the white cells and apply to them the process described in <this article>. Assuming this actually turns the adult white cells into stem cells, which ...
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1answer
39 views

Stem cell that can pass through blood vessel

I know that blood cells can pass through the smallest of capillaries, but I was wondering is it possible for stem cells to pass through the smallest of capillaries? In other words, is it possible for ...
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What is the general name of the chip to simulate organ systems by iPS?

I listened the last few Nature Medicine podcasts. They are talking about some chips that are used with iPS cells to simulate the action of antigens in organ systems. Is there any review articles ...
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36 views

Can TGF beta family induce all somatic stem cells?

I think this is not possible. Conclusion about this preview article TGF-$\beta$ family signaling in stem cells: While TGF-$\beta$ family signaling regulates stemness of normal and cancer stem ...
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3answers
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Does a reduction in stem cells mean possible earlier death?

The basis of this question relies on my understanding of these 2 facts: ...
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How can stem cells be counted in body?

In the study of supercentenarian woman here, it was found that all her blood cells are formed from only two stem cells (ancestor stem cells). How scientists can distinguish cell ancestors? Aren't ...
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Why are embryonic germ cells considered stem cells?

In a class that I'm taking we were presented 3 types of stem cells. Adult stem cells which come from bone marrow Embryonic stem cells which come from embryos Embryonic germ cells which come from ...
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1answer
81 views

Solubility of Forskolin in ethanol

I am interested in using forskolin in cell culture medium. Does anyone know how to make solution of 10 microM forskolin in 5% ethanol or less. I would like to avoid using DMSO as a solvent. Thank you. ...
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1answer
56 views

The contribution of stem cells to life extension technology [closed]

What do you think is the most powerful method to extend human lifespan? I want to extend human life span significantly (hopefully extra 50 years or more), so I was expecting that stem cell technology ...
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1answer
38 views

An over-simplified model of cell division and its relation to stem cells

I am a mathematician, and I decided to try to model cell division with math and see what conclusions came out of it. I had some questions concerning stem cells that came up in the model. In an ...
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3answers
115 views

Can humans be printed?

Is it possible to spray stem cells on fully grown skeleton to get fully grown humans? Currently, just read about recent advances, and wondered if something like this is possible.
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How do transplanted stem cells find their way to bone marrow?

Miraculously, transplanted stem cells find their way to the bone marrow missing the stem cells. How do they achieve this?
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1answer
29 views

potency in preformed germ-line

In organism that have a preformed germ-line like Drosophila where germ cells are pre-allocated in the oocyte, are there technically no adult pluripotent stem cells since germ line cells can't be ...
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386 views

What is the difference between “lineage restriction” and “differentiated” in terms of stem cell biology

Is there a subtle difference between these two concepts or are they basically the same thing? When I mean differentiated, I don't mean terminally differentiated.
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Movement of stem cells from mother to fetus

Recent results from J Lee Nelson and colleagues (Sci Am. 2008 Feb;298(2):64-71; available as full text through Google) show that cells from the mother were found in a person aged 46. Logically, these ...
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1answer
34 views

Transplantation of stem cells

During the autologous transplantation of stems cells from bone marrow to produce new blood cells why all the other stem cells other than the one obtained are destroyed?
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Is it possible to print humans?

According to this news, scientists can use stem cells to print objects. So say theoretically, is there any possibility to print human beings?
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1answer
485 views

Role of Fbx15 in ES cells and its use in assaying for iPS cells (Yamanaka paper and others)?

I am trying to understand the assay for iPS cells in the Takahashi & Yamanaka 2006 paper. They inserted a beta-geo cassette, which contains the neomycin resistance gene, into the Fbx15 gene. The ...
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1answer
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How might IVF (and related technologies) alter epigenetic marks?

I was reading up on KCNQ1, which encodes a voltage-gated potassium channel, and I discovered that it happens to be only maternally expressed. This is regulated by KCNQ1OT1, a non-coding RNA, which is ...
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2answers
281 views

How are different types of cells created from zygote?

In the process of mitosis that starts from zygote, how do different cells appear? What happens that some cells become one type and some another? For example, is there a cell that divides into a ...
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1answer
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Does every gland type have stem cells for regeneration?

Is there any gland in which there are no stem cells? I know that: sebaceous gland is maintained by unipotent stem cells thyroid gland - some stem cells, apparently unipotent Glands about which ...
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0answers
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What metabolically happens when an egg fuses with the nucleus of a somatic cell

In stem cell biology, it is recognized that embryonic stem cells are transcriptionally inactive for the first 3 days of development. However, during somatic cell nuclear transfer, the nucleus is ...
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How similar are Circulating Tumor Cells and Cancer Stem Cells?

Circulating Tumor Cells (CTCs) are linked with metastasis and their presence can be used to indicate the onset of metastatic cancer. Likewise, the Cancer Stem Cell (CSC) hypothesis suggests that ...
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Possible? When a pregnant woman suffers an organ damage, fetus would send stem cells to the damage organ to help repair it?

I am quite sure that there is this blood-placental barrier between the mother and the baby so that nothing (except a type of antibody) can pass through it. But I remember reading somewhere that when ...