Cells which have not fully differentiated yet, i.e. with the potential to develop into other kinds of cells through asymmetric cell division.

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What metabolically happens when an egg fuses with the nucleus of a somatic cell

In stem cell biology, it is recognized that embryonic stem cells are transcriptionally inactive for the first 3 days of development. However, during somatic cell nuclear transfer, the nucleus is ...
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32 views

How can stem cells be counted in body?

In the study of supercentenarian woman here, it was found that all her blood cells are formed from only two stem cells (ancestor stem cells). How scientists can distinguish cell ancestors? Aren't ...
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67 views

Movement of stem cells from mother to fetus

Recent results from J Lee Nelson and colleagues (Sci Am. 2008 Feb;298(2):64-71; available as full text through Google) show that cells from the mother were found in a person aged 46. Logically, these ...
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How can one measure the effect of a stem cell's matrix on the progeny of that stem cell?

A number of recent papers that have used hydrogels to alter the ECM of mesenchymal stem cells to quicken their development to cells used specifically for cartilage or really any other type of cell. ...
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final control prior to transfecting an expression vector into a mammalian cell?

I have been asked a general question: Once I have cloned a full-length cDNA into an expression vector, what final important control must I do before I transfect this into an embryonic stem cell line? ...
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Comparing Embryonic stem cell and hepatic stem cell

So, currently, I want to compare transcriptome data for liver cell development. I found 2 data sets which start from stem cell, hepatoblast, and then adult cell. The first data set use hepatic stem ...
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132 views

Which of these methods is both effective and reliable in elongate muscle and tendon for use in humans: growth factors or stem cell technology

Which method is it the most effective, but also the most reliable for elongating muscle and tendons for clinical trial; using modern growth factor technology or using modern stem cell technology? ...
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42 views

from an ageing reproductive stem cell's DNA to baby's “brand new” somatic cells' DNA

On the one hand, somatic cells's DNA age as life goes on, mitosis after mitosis, and that is reflected into reduced telomeres. On the other hand, during life, reproductive stem cells must age too. ...
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24 views

Is this a legitimate teratoma for a human pluripotent stem cell assay?

I can't quite make out this teratoma:                            ...
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32 views

How do expression levels change along lineages?

Is there any general trend between gene expression levels (or transcription levels) and cell lineages? For example, I would naively expect that stem cells express less genes as they have the ability ...
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8 views

Number of LT-HSCs in mice and humans

I am looking for the number of long term hematopoietic stem cells in both humans and mice if somebody has references for these two numbers. I have very old estimates, but I would like something much ...
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27 views

Stem cells and if they can correct a lack of apoptosis

If a cell ,call it C1 has no functioning apoptosis mechanism could a stem cell somehow be 'induced' to be like C1 , at least have the same genome as C1. Then use this stem cell 'duplicate' to 'restart'...