Cells which have not fully differentiated yet, i.e. with the potential to develop into other kinds of cells through asymmetric cell division.

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Possible? When a pregnant woman suffers an organ damage, fetus would send stem cells to the damage organ to help repair it?

I am quite sure that there is this blood-placental barrier between the mother and the baby so that nothing (except a type of antibody) can pass through it. But I remember reading somewhere that when ...
6
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1answer
353 views

How similar are Circulating Tumor Cells and Cancer Stem Cells?

Circulating Tumor Cells (CTCs) are linked with metastasis and their presence can be used to indicate the onset of metastatic cancer. Likewise, the Cancer Stem Cell (CSC) hypothesis suggests that ...
5
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1answer
96 views

Is there any scientific evidence that a human has ever grown a third set of teeth?

This is about the possibility (or lack thereof) for a person to re-grow a new "permanent tooth" or set of teeth, to replace the teeth that grew after their milk teeth fell out. I had earlier seen ...
5
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1answer
149 views

Does every gland type have stem cells for regeneration?

Is there any gland in which there are no stem cells? I know that: sebaceous gland is maintained by unipotent stem cells thyroid gland - some stem cells, apparently unipotent Glands about which ...
4
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1answer
631 views

What is the difference between “lineage restriction” and “differentiated” in terms of stem cell biology

Is there a subtle difference between these two concepts or are they basically the same thing? When I mean differentiated, I don't mean terminally differentiated.
4
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1answer
36 views

How to make sure a stem cell culture is cancer free?

Say I take a blood sample from an adult, extract the white cells and apply to them the process described in <this article>. Assuming this actually turns the adult white cells into stem cells, which ...
4
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0answers
29 views

What metabolically happens when an egg fuses with the nucleus of a somatic cell

In stem cell biology, it is recognized that embryonic stem cells are transcriptionally inactive for the first 3 days of development. However, during somatic cell nuclear transfer, the nucleus is ...
3
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1answer
91 views

What type of flask should I use to culture NTERA2 embryonic cancer stem cells?

I'm just starting my MSc research and I am in the process of making a list of equipments/consumables to order. Is there a specific flask in which I can culture NTERA2 (NTERA2/D1) cell line?
3
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3answers
120 views

Can humans be printed?

Is it possible to spray stem cells on fully grown skeleton to get fully grown humans? Currently, just read about recent advances, and wondered if something like this is possible.
3
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3answers
106 views

Does a reduction in stem cells mean possible earlier death?

The basis of this question relies on my understanding of these 2 facts: ...
2
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1answer
33 views

potency in preformed germ-line

In organism that have a preformed germ-line like Drosophila where germ cells are pre-allocated in the oocyte, are there technically no adult pluripotent stem cells since germ line cells can't be ...
2
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2answers
345 views

How are different types of cells created from zygote?

In the process of mitosis that starts from zygote, how do different cells appear? What happens that some cells become one type and some another? For example, is there a cell that divides into a ...
2
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1answer
42 views

Stem cell that can pass through blood vessel

I know that blood cells can pass through the smallest of capillaries, but I was wondering is it possible for stem cells to pass through the smallest of capillaries? In other words, is it possible for ...
2
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1answer
118 views

Solubility of Forskolin in ethanol

I am interested in using forskolin in cell culture medium. Does anyone know how to make solution of 10 microM forskolin in 5% ethanol or less. I would like to avoid using DMSO as a solvent. Thank you. ...
2
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0answers
26 views

How can stem cells be counted in body?

In the study of supercentenarian woman here, it was found that all her blood cells are formed from only two stem cells (ancestor stem cells). How scientists can distinguish cell ancestors? Aren't ...
2
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0answers
60 views

Movement of stem cells from mother to fetus

Recent results from J Lee Nelson and colleagues (Sci Am. 2008 Feb;298(2):64-71; available as full text through Google) show that cells from the mother were found in a person aged 46. Logically, these ...
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2answers
207 views

Is it possible to print humans?

According to this news, scientists can use stem cells to print objects. So say theoretically, is there any possibility to print human beings?
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1answer
33 views

Is there a stem cell dye for education purposes?

I need a dye that will stain stem cells (for this purpose the stem cells will proquired from chicken bone marrow). This will be an educational hands on activity for young teenagers so ideally the dye ...
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2answers
34 views

Why don't stem cell therapies use viruses?

Why don't stem cell therapies use a virus to deliver gene editing sequences to stem cells instead of the harvesting-transformation-transplant route. I thought it might be because of a lack of ...
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1answer
36 views

Transplantation of stem cells

During the autologous transplantation of stems cells from bone marrow to produce new blood cells why all the other stem cells other than the one obtained are destroyed?
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1answer
667 views

Role of Fbx15 in ES cells and its use in assaying for iPS cells (Yamanaka paper and others)?

I am trying to understand the assay for iPS cells in the Takahashi & Yamanaka 2006 paper. They inserted a beta-geo cassette, which contains the neomycin resistance gene, into the Fbx15 gene. The ...
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0answers
15 views

from an ageing reproductive stem cell's DNA to baby's “brand new” somatic cells' DNA

On the one hand, somatic cells's DNA age as life goes on, mitosis after mitosis, and that is reflected into reduced telomeres. On the other hand, during life, reproductive stem cells must age too. ...
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0answers
18 views

Is this a legitimate teratoma for a human pluripotent stem cell assay?

I can't quite make out this teratoma: ...
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0answers
22 views

Why are embryonic germ cells considered stem cells?

In a class that I'm taking we were presented 3 types of stem cells. Adult stem cells which come from bone marrow Embryonic stem cells which come from embryos Embryonic germ cells which come from ...
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1answer
102 views

How might IVF (and related technologies) alter epigenetic marks?

I was reading up on KCNQ1, which encodes a voltage-gated potassium channel, and I discovered that it happens to be only maternally expressed. This is regulated by KCNQ1OT1, a non-coding RNA, which is ...
0
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1answer
32 views

What are iPSC cells, and what are their applications? [closed]

I also searched it on internet, and just basically know it's related to the Stem Cells, but there are too many resources, can anyone help me find out more about them, like their applications? They ...
0
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1answer
47 views

An over-simplified model of cell division and its relation to stem cells

I am a mathematician, and I decided to try to model cell division with math and see what conclusions came out of it. I had some questions concerning stem cells that came up in the model. In an ...
0
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1answer
38 views

Can TGF beta family induce all somatic stem cells?

I think this is not possible. Conclusion about this preview article TGF-$\beta$ family signaling in stem cells: While TGF-$\beta$ family signaling regulates stemness of normal and cancer stem ...
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1answer
59 views

How do transplanted stem cells find their way to bone marrow?

Miraculously, transplanted stem cells find their way to the bone marrow missing the stem cells. How do they achieve this?
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15 views

How are Stem Cells Produced for Stem Cell Based Therapies?

I was doing an initial search on google but couldn't come up with anything I'm looking for. I know were stem cells come from and a bit about their levels of differentiation. For example, embryonic ...
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0answers
13 views

Stem cells and if they can correct a lack of apoptosis

If a cell ,call it C1 has no functioning apoptosis mechanism could a stem cell somehow be 'induced' to be like C1 , at least have the same genome as C1. Then use this stem cell 'duplicate' to ...