Tagged Questions

How terms are used or the meaning of words as used in scientific literature. Questions should ideally include a link or quote as context for where the term was encountered.

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1answer
2k views

Is episome a plasmid or a virus?

A plasmid is a small DNA molecule that is physically separate from, and can replicate independently of, chromosomal DNA within a cell. In general, in eukaryotes, episomes are closed circular DNA ...
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1answer
89 views

Confusion related to a term probe-by-background interaction

I was reading a paper related to bioinformatics where it uses the drug response on the cancer cells and the gene expression of the individual cells are studied to find any useful insights. Specially, ...
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1answer
302 views

Definition of Dye- Reduction Test?

Can some one give a simple explanation or definition on what a dye-reduction test is.
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1answer
40 views

What does “Psychomodulatory” mean in the context of potentially psychoactive drugs?

What does "Psychomodulatory" mean in the context of potentially psychoactive drugs? That is, in this journal article http://www.sciencedirect.com/science/article/pii/S0028390812001931 in the ...
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1answer
2k views

What is immunopanning (vs. immunoprecipitation and FACS)?

I had never heard the term before today. From what I can tell, it's using antibodies to purify a cell population of interest. I would appreciate more details, especially in how it differs from ...
1
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1answer
112 views

What is background binding?

I'm reading a journal article about mitochondrial protein import and it mentions that one of the mutant proteins tested showed background binding with another protein. What the heck is background ...
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1answer
477 views

What is Chronic immobilization stress (CIS)?

I am trying to self study BNDF a little bit when I found this article: Abstract Stress impacts multiple systems within the CNS, including the hippocampus. A key molecular mediator in hippocampal ...
3
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1answer
57 views

Is there a term to quantify how spread a character is on a phylogenetic tree?

Is there a term which can quantify how 'spread out' a particular character is on a tree? I want to distinguish between a character which is only restricted to a particular clade vs. a character that ...
3
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2answers
866 views

Transcript(omics) terminology: cDNAs, ESTs, RNA-seq, etc

I've worked pretty frequently with genome and transcriptome data for several years now, but I'm still not 100% sure I understand the proper usage for certain terminology related to transcripts and ...
3
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0answers
94 views

Terminology question: the scope of an allele in an organism

Let us consider a gene FOO with novel type foo. If I were discussing an organism that has inherited foo in every cell during classical zygote formation, then I would ordinarily just say that the ...
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5answers
3k views

Difference between genetic engineering and synthetic biology

I've recently seen the term synthetic biology being used to describe research involving genetic modification of organisms. What is the difference between synthetic biology and genetic engineering? Is ...
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1answer
1k views

What is a focal copy number variation?

Often, genetics studies, especially genome wide ones, talk about "focal copy number variations" in genes or regions of the chromosome. I know what a copy number variation is. What does "focal" mean, ...
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4answers
1k views

Can the third sex be categorized as Male or Female?

Hijra are people who have a penis (not sure if sexually active) but look much like a female (perhaps for some feminine biological property). Wikipedia says they are "physiological males who have ...
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3answers
1k views

Are there verbs for “undergo mitosis” and “undergo meiosis”?

From my experience on SE sites, I believe this is the right site to ask this question under "terminology". I've been trying to find out whether English has one-word verbs for "undergo mitosis" and ...
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3answers
2k views

Is “computational biology” different from “bioinformatics”?

Are "computational biology" and "bioinformatics" simply different terms for the same thing or is there a real difference?
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2answers
8k views

Calculating Protein Concentration from Kilo Units (KU)

I am looking to purchase Pyruvate Kinase from the Sigma Website, they state the volume in Kilo Units (KU) i.e. 1, 5 or 25 KU. It also states there are 350-600 units / mg protein. Does this mean one ...
3
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1answer
4k views

What does the term 'bioavailability' mean?

From what I've read, Bioavailability is the degree to which food nutrients are available for absorption and utilization in the body. How would you explain this with an example?