The branch of biology, chemistry, and medicine concerned with the study of the adverse effects of chemicals on living organisms.

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How does cytochrome c oxidase inhibition cause cell death?

I realise the inhibition of cytochrome c oxidase prevents the release of H+ ions into the intermembrane space, and that the ion gradient is required for ATP synthase action. However, I'm not sure how ...
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Is there a metabolic pathway that generates methanol?

I've been looking for help topics about methanol in metabolism. Specifically, I wish to know what is a common dietary component that generates methanol following metabolism and comment on its ...
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Nail polish toxicity studies?

Are there any well-founded studies that authoritatively demonstrate negative effects from the use of nail polish, particularly in children? I've been brought into the fray of a couple of folks who ...
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MTT assay normalization

Since the precise amount of cells in each well of an MTT assay varies, how can I normalize the results by cell number/concentration? How can I take into account the number of cells that have already ...
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Why does heating kidney beans at a low temperature potentiate the toxicity of phytohaemagglutinin?

I recently found out that red kidney beans contain a relatively high amount of the toxic lectin, phytohaemagglutinin. An article on phytohaemagglutinin on the FDA website states: Several ...
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Persistency of botulinum toxin in environment

There is information about decontamination times here on pages 6 and 7. My specific question is how persistent botulinum toxin is in a natural environment, or alternatively, what is the half life of ...
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Medical Uses of toxic venom

One interesting thing I recently learned is that venom has medical uses that can actually save lives! But from what I see so far this either applies to venoms from creatures that are not fatal to ...