The branch of biology, chemistry, and medicine concerned with the study of the adverse effects of chemicals on living organisms.

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What happens if someone with mutations to alcohol dehydrogenase (ADH) drinks alcohol?

ethanol then doesn't get converted to acetaldehyde. in fact, could someone KO'ed for ADH be resistant to methanol poisoning?
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Can Squirrels Eat Every Mushroom?

Squirrels have the ability to eat toxic mushrooms as described below. Are there any mushrooms that they can't eat without dying? According to Dr. John Rippon, an IMA member and world expert on ...
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MTT assay normalization

Since the precise amount of cells in each well of an MTT assay varies, how can I normalize the results by cell number/concentration? How can I take into account the number of cells that have already ...
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What do genotoxic scoring (Sa) values mean?

The genotoxic scoring is an estimator of genotoxic potency whose values range from 100 to -100. What is the interpretation of those different positive and negative values? (for instance ethanol Sa= ...
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Can people with loss-of-function mutations to CYP2E1 be resistant to benzene poisoning?

CYP2E1 is what converts benzene into oxo-benzene. It's oxo-benzene which damages DNA. So I'm curious - what about people who don't have this enzyme?