Tuberculosis is a disease caused by the bacterium Mycobacterium tuberculosis. It infects mainly the lungs, but can be found in other parts of the body. Untreated tuberculosis ends fatal.

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Is disease transmisson through milk consumption or meat consumption considered direct or indirect transmission route?

From an epidemiological point of view, is consumption of raw milk or meat considered as indirect or direct transmission ? Let's take the example of bovine TB. Is consumption of unpasteurized milk ...
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Where’s the flaw in my proposed TB Treatment?

Ten years ago, I emailed a prominent lung specialist with my suggestion for a treatment for Tuberculosis. His lack of response led me to believe that the idea had no merit whatsoever – but I had no ...
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How to do a whole genome analysis of Multidrug-resistant Mycobacterium tuberculosis

I'm looking for tutorials and software that can help me study whole genome sequence data is and genome wide associations. I have Matlab and Bioconductor R so anything involving those packages would be ...
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What (if anything) about tuberculosis makes producing a highly effective vaccine difficult?

What about tuberculosis makes it difficult to produce a safe vaccine that is effective at producing an immunogenic response in >99% of individuals against all strains of the bacteria? I am aware of ...
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TB disease - treatment and infection

Background: I'm currently performing research in mathematical biology, specifically on the treatment dynamics of HIV and TB co-infection. Question: Can a person infected with TB disease, who are ...
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Why PPD test in patients without M.tuberculosis often slightly positive?

I got this question which I interpret as Why PPD test in patients without M. tuberculosis often have slightly positive PPD reaction i.e., a lifelong slightly positive skin test reaction? because ...
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Why HIV patients have greater virulence of M.tuberculosis?

I am reading Murray Microbiology book. Some facts M. tuberculosis is an intracellular pathogen. At the time of exposure, M. tuberculosis enters the respiratory airways and infectious particles ...
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What are the characteristic structures of bacillus M. tuberculosis and what they cause?

I answered to this question: In most forms of the disease, the bacillus M. tuberculosis spreads slowly and widely in the lungs, causing the formation of hard nodules (tubercles) in the ...
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Can acid-fast M. tubercolosis obstruct alveoli?

I am not sure which word is the best here for colonisation of alveoli by acid fast-mycobacteria. I found this question, and I am getting confused by the term obstruction of alveoli because I tend to ...