Virology deals with the study of viruses, infectious entities that require the machinery of a host cell to replicate.

learn more… | top users | synonyms

0
votes
0answers
4 views

Switching of life cycle Lambda phage

Hello everyone iam very curious to know how the lambda phage switch their life cycle (lysogenic and lytic cycle). I want to know the detailed mechanism by which this switching occurs in the phage.
1
vote
0answers
18 views

Can 3% hydrogen peroxide be used as effective disinfectant and antiseptic?

I was curious to see whether 3% hydrogen peroxide can be used as antimicrobial and virucidal product for daily use in home. There are several disinfecting products in the market claim that use of ...
2
votes
0answers
21 views

Viruses affecting transmission capability of mosquitoes

I've read about bacteria affecting the transmission capability of mosquitoes. For example: Wolbachia suppresses dengue transmission When mosquitoes were given antibiotics that decreased their gut ...
0
votes
0answers
24 views

What are the real chances of HIV transmission? [closed]

I am really confused about this matter (as far as transmission via sexual intercourse is concerned). I've heard a lot of versions from doctors and on internet. To be more specific: A pathologist ...
4
votes
1answer
73 views

Why can't we find a broad spectrum antiviral drug to viruses like antibiotics to bacteria?

Antibiotics have a very broad spectrum because they attack the metabolism pathways many bacteria share. For example, penicillin inhibits peptidoglycan synthesis, which is vital for formation of cell ...
0
votes
1answer
9 views

Since RNA viruses and retroviruses all have high mutation rates, why do only a few viruses have the virtue of variability?

We have been taught that it's difficult to make vaccines to influenza, HIV and HCV because they lack the proofreading mechanism, hence have high mutation rates. But most RNA viruses and retroviruses ...
2
votes
0answers
10 views

Do all +ssRNA viruses have similar structures and life cycles?

Take HCV for example. HCV doesn't package any enzymes in it's virions. When it infects a cell, it first translates its RNA genome. It's RdRp is synthesized with other non-structural proteins. Then its ...
-3
votes
1answer
40 views

Does SIV cause AIDS in primates… If not why [closed]

does SIV cause AIDS in primates or have they developed resistance to the virus **
1
vote
0answers
9 views

Can HPV be infectious after it's been exposed to environment?

From what I know, HPV virus cannot be cultured I don't think it's possible to say if a sample has the potential to infect or not but what does it mean when they say HPV virus particles could persist ...
0
votes
0answers
17 views

How effective will the synthesized virus be without epigenetic marks?

Will a de-novo synthesize infectious virus be as effective as the natural one? How important are epigenetic marks for the virus and is there a mechanism to restore them?
0
votes
0answers
22 views

How does the body know to stop effector cell proliferation?

After a pathogen has been successfully neutralized, effector cells such as the plasma cells and the cytotoxic T cells which are specific for that pathogen decrease in numbers. What is the signal in ...
0
votes
0answers
13 views

Are there well studied examples of ERAD-mediated membrane insertion, especially from viruses?

Membrane insertion of transmembrane proteins typically requires highly hydrophobic alpha helixes at the N-terminus, N-terminal signal peptides, tail anchors, or a combination of the three. Byun, H., ...
4
votes
0answers
31 views

What are the secondary structure requirements for cell-penetrating peptides AKA protein transduction domains

Cell penetrating peptides. Cell penetrating peptides (CPPs) are a class of short amino acid sequences which are sufficient for crossing cell membranes and delivering themselves along with any ...
5
votes
0answers
53 views

Why do viruses last longer on hard surfaces than porous ones

All the papers I've read about survival of viruses outside of the host refer to longer survival times on hard surfaces without explaination. As a layman I would have thought that a virus (who's main ...
6
votes
1answer
297 views

Is there any virus that contains both DNA and RNA in its genome?

It is known that viruses contain DNA or RNA- either one and not both. I came across a question: Which virus contains both DNA and RNA?
12
votes
2answers
182 views

Can viruses be toxic?

Bacteria can produce toxins like endotoxins and exotoxins. In diseases like cholera or tetanus they can harm infected people due to these toxins. Now, although viruses are much smaller and are ...
6
votes
1answer
63 views

Is Zika suspected of causing birth defects only if contracted during pregnancy?

There seems to be growing evidence that a recently spreading strain of Zika virus is in fact linked to microencephaly and other birth defects in newborns (see here, here, and here for examples). I ...
1
vote
1answer
81 views

Why does HPV Infect Squamous Epithelial Cells and Not Others?

I've seen this question about HPV and the reference therein. The link states "Human papillomavirus (HPV) is a DNA virus that presents tropism for epithelial cells, causing infections of the skin and ...
0
votes
0answers
20 views

How does a viral capsid undergo self assembly?

We know that viral capsids are formed by self assembly but there is surprisingly little information about how it is done specifically. Can somebody find video representation along with explanation, ...
0
votes
1answer
61 views

How to obtain virus samples?

I'm trying to observe the behavior of simple viruses in different environments. I'm just looking for simple viruses like the common cold and the flu virus nothing major. Is there a way to obtain them?
0
votes
1answer
112 views

How many virus infections does the average human have? [closed]

According to the WHO: 67% of the population are infected with herpes simplex virus type 1 (HSV-1) Presumably there are other viruses as well that infect a lot of people. How many infections ...
18
votes
2answers
2k views

Can Biologists identify all viruses?

I went to the doctor today with my girlfriend, and the doctor said that she had a virus but doesn't know which one and she should let the infection heal with some rest. The fact that the doctor didn'...
-3
votes
1answer
81 views

Advocate for the pop-culture idea of withholding vaccination [closed]

While it is widely accepted that vaccination is preferable to not vaccinating, would anyone like to give a shot at providing evidence in favor of not vaccinating? Anything goes.
2
votes
0answers
68 views

HIV and open reading frames

In Wilk et al. 2001 I saw that HIV has 3 open reading frames. In the Watts et al. 2009, I noticed they mentioned HIV has 9 open reading frames. I don't understand this very well. e.g. ...
13
votes
1answer
596 views

How heavy are all foreign microorganisms in and on the human body?

I define "foreign microorganism" as a microorganism which is not produced by the human body (not antibodies or leukocytes) including bacteria, viruses, fungi, biofilm aggregates or small lifeforms ...
3
votes
1answer
65 views

Virus-to-virus gene transfer via “sequences integrated into a common host organism”

From "Risks from GMOs due to Horizontal Gene Transfer", by Paul Keese: In addition to direct HGT between organisms as depicted in Figure 1, forms of indirect HGT have been observed, which involve ...
1
vote
1answer
30 views

In vitro virus assembly

Are researchers able to assemble viruses in vitro? For example, I imagine that a phage display library may be generated by throwing in a test tube the capsid proteins (or what have you) along with ...
0
votes
1answer
57 views

Meaning of “non-homologous virus”

From "Risks from GMOs due to Horizontal Gene Transfer", by Paul Keese: More recently, concerns have been raised that HGT from genetically modified organisms (GMOs) could have adverse effects (...
0
votes
1answer
61 views

Interpretation of faint band for Linear Array HPV Genotyping Test

After having used the test for research it would appear as if it is very specific. What is one to make of bands that are there but faint? Or what if there are two bands and one is big and bold and the ...
1
vote
2answers
36 views

Secretion in Gram negative bacteria

Among the 6 secretion systems in bacteria, can these 6 ways be sorted out in the order of how harmful it is to the human host? Like say type 3 is highly virulent so that comes first, but I don't know ...
0
votes
1answer
38 views

What is the difference between options protein and replication in the NCBI database?

After checking the NCBI help page, I am still unclear about the difference between protein and replication interactions for HIV. http://www.ncbi.nlm.nih.gov/genome/viruses/retroviruses/hiv-1/...
2
votes
0answers
91 views

Recommendations for an intro level virology textbook? [closed]

I'm a college sophomore, and I was just accepted into a research lab that works with retroviruses. Since I haven't taken any classes on the topic yet, does anyone have recommendations for good, intro-...
6
votes
1answer
108 views

Viruses selected by evolution

First let me apologize in advance for I know almost nothing about biology. I had a conversation today with a family member who is a bio-computer-scientist and he talked to me about what his colleagues ...
5
votes
2answers
241 views

How does a virus reach its host, it is always passive? [closed]

We know that viruses are non motile and cannot metabolise, and that it enters the host cells via binding to the receptors. But how exactly it reaches the host (that is, how it go from the ...
4
votes
1answer
185 views

Lentivector biosafety

Lentivectors are widely used in molecular biology, most commonly to transduce in a stable way a desired gene. These vector system takes advantage from the ability of viruses to introduce their own ...
3
votes
2answers
172 views

What is correct MVM vs. MMV?

I'm writing up a report and I see conflicts everywhere on the internet. Should it be Murine Minute Virus (MMV) or Minute Virus of Mice (MVM). The followup question is does it really matter.
4
votes
0answers
65 views

What percentage of cells in the human body are infected during a non-fatal viral infection?

I understand that this would be a very rough estimate, but approximately how many cells in the human body are infected during an average non-fatal viral infection before the infection is eliminated by ...
3
votes
0answers
42 views

Should gene therapy safety protocol include isolation?

In the case of a gene therapy trial where viral vectors are used to deliver genes into mammalian cells, including humans, should biosafety and ethical protocols include isolation of the patient as a ...
2
votes
2answers
60 views

Are there any DNA sequences shared by all/most Viruses?

Is there any one DNA sequence shared by all or most viruses? I highly doubt there is mainly because of how different all of them are, but it's still worth a try. Thanks
3
votes
1answer
44 views

Are some virus loads introduced to human cell but never triggered?

Is there a term or any evidence of phage DNA integrating into chromosomes/ DNA but never being triggered? For example, could a virus that affected Neanderthals still infect human cells today but is ...
4
votes
0answers
68 views

Are there any viruses that have infected all humans in the past or present? [closed]

Are there any known viruses that have managed to infect all of humankind either in the past or presently, either benign or otherwise?
0
votes
0answers
43 views

Are there any viruses that are part of all land animals?

An article on I Fucking Love Science (linked to below) got me thinking, are there any viruses that have been so successful that they have spread to all land animals similar to Toxoplasmosis which has ...
3
votes
2answers
123 views

What does the gene name “lexA” stand for?

It is an important gene expressed in E. coli that represses the SOS response and also the expression of lambda lytic phase genes. UV light and damage to DNA is responsible for its breakdown and hence ...
6
votes
2answers
182 views

Balanced vs Maximized Codon Optimization

I have worked with the optimization of several viral proteins, from different viruses/families, with different results. When Menzella, 2011 was published I tried that method. I found quite the ...
5
votes
5answers
98 views

Can an influenza virus carry other infectors with it?

This idea came to my mind when thinking about how many people become ill in many locations with similar symptoms (fever and rough cough) from Influenza. There are of course different types of ...
3
votes
2answers
89 views

Hydrophobia Outside of Rabies?

RELATED: Why does rabies cause hydrophobia? Agony, Hydrophobia and viruses in the light of evolutionary principles Has hydrophobia been found outside of rabies? I have only seen it ...
3
votes
1answer
127 views

At which temperature is the Tick-Borne Encephalitis Virus destroyed?

At which temperature is the Tick-Borne Encephalitis Virus destroyed? If there is no data specifically for TBEV, is there any data for typical temperatures at which other Flaviviruses / Flaviviridae / ...
7
votes
1answer
116 views

How exactly can dsRNA be introduced to a cell?

Is it just by viruses or are there other means by which it gets into cells, such as plasmid uptake?
9
votes
2answers
2k views

To what extent is Ebola airborne? (aerosols)

Recently, CIDRAP at the University of Minnesota announced that Ebola may be more transmissible through aerosols than previously thought. I lack the familiarity with the field to critically evaluate ...
11
votes
2answers
2k views

How long does the Ebola virus remain infectious on contaminated items or surfaces?

I'm sure there will be variation depending on what the contaminated item or surface is made of - linens, I could imagine, would remain dangerous for longer than a door-knob. But if the items are not ...