2
votes
1answer
16 views

What are these tiny dark red insects?

I found these creatures stuck to a leaf on my tomato plant in the greenhouse/glasshouse, in early June, in south Oxfordshire in the United Kingdom. They are each about 1-2mm in size. They didn't move ...
0
votes
2answers
34 views

What are the programming languages important to learn for a geneticist or bioinformatician? [on hold]

I am interested in learning more about both genomics and bioinformatics, with emphasis on genomics. I was told after taking an introductory course of genomics that the programming language "R" and ...
2
votes
1answer
21 views

How do carrier RNAs increase yield in sequencing experiments?

I would like to know how carrier RNAs increase yield in RNA/DNA sequencing experiments. Is their main function in the precipitation steps of each protocol (i.e. small quantities are difficult to ...
1
vote
0answers
6 views

Which anti-fungal compounds effective against Grosmannia clavigera?

Grosmannia clavigera ("Blue Stain Fungus") is the fungus introduced by Dendroctonus ponderosae ("Mountain Pine Beetle") when they infest their host (several species of Pinus). Are there any known ...
2
votes
1answer
32 views

Extract protein sequences from a GBK(GenBank) file without scripting [on hold]

How to extract protein sequences from a GBK(GenBank) file without scripting? I know that writting a script using BioPerl or Biopython can do this, but it is not elegant and daunting to beginners and ...
1
vote
0answers
10 views

Which pathway visualization software can I mouse-over the name to view molecular structure? [on hold]

As the title implies, I'm looking to use a single pathway visualization program to learn pathways. All that I can find, like wikipathways, only show the names of the molecules, with an option to click ...
3
votes
1answer
29 views

What are the units of Phylogenetic Independent Contrasts (PICs)

PICs are a popular phylogenetic comparative method and I was wondering what units the actual contrasts are in. I want to say they are unitless but I am not entirely sure.
0
votes
0answers
8 views

Mutation rate during meiosis and mitosis

Many more mutations occur during meiosis than during mitosis. However, in many multicellular organisms, germ cells undergo many mitosis (during the development) before undergoing meiosis. I think that ...
11
votes
4answers
2k views

Where’s the flaw in my proposed TB Treatment?

Ten years ago, I emailed a prominent lung specialist with my suggestion for a treatment for Tuberculosis. His lack of response led me to believe that the idea had no merit whatsoever – but I had no ...
3
votes
2answers
72 views

The selective pressure of contraceptives

Does it seem probable that the existence of contraceptives (which has reduced human reproduction to below survival-level in many populations) will be a completely new selective pressure on human ...
1
vote
1answer
18 views

Hodgin-Huxley model for a single neuron - continuation

As continuation to This question I have posted. Another set of questions is given for the same model : This time it is also given that for $t<0$ the membrane potential is $u_0$, and at $t=0$ it ...
1
vote
1answer
21 views

Can Nanodiscs be used to study membrane energetics?

Nanodiscs have changed they way we can study the structures, insertion, and functions of transmembrane proteins. Below is an image of a nanodisc bilayer. The key difference, as far as I can tell, ...
12
votes
2answers
98 views

How can we verify predictions of protein folding in silico?

Currently, there is a lot of research focused on solving the folding patterns of proteins using computers (Folding@Home, https://fold.it/portal/, etc.). The question that I have is: How do you know ...
0
votes
1answer
21 views

How reliable is SwissProt topology?

I am using TOPO_DOM annotations from uniprot databases to characterise the orientation of transmembrane features. Is SwissProt topology experimentally validated, ...
2
votes
1answer
66 views
+50

Explanation of ECG in MI using an electrostatic model

I found a paper presenting an electrostatic model to explain the ECG recorded in various leads. This model essentially calls for considering the depolarization wavefront to be the major contributing ...
0
votes
1answer
22 views

Why can't this be 1st meiotic division non-disjunction as well?

The child has gotten 2 "sick" chromosomes from his dad and 1 healthy from his mom, leaving it with trisomy 13. I can see how this can happen in the second meiotic division of the father but I can ...
1
vote
0answers
9 views

Differences in structural target for LPS detection by LAL and MD-2/TLR4

I remember there being a significant difference in the pathogen-associated molecular patterns (PAMPs) used for detection of lipopolysaccharide (LPS) by mammalian cells and the Limulus amoebocyte ...
2
votes
0answers
23 views

Can two members of the same sex have a biological baby? [duplicate]

I imagine that this would work using a similar technique to dolly the sheep. For two females, the nucleus of an egg would be placed in a sperm which has had its nucleus removed. The 'female' sperm ...
0
votes
0answers
19 views

How calorie intake affects weight gain?

There are ton's of textbooks and websites that say that if you want to gain weight you have to increase your calorie intake. My question is how is it possible for a body to take in more calorie than ...
1
vote
1answer
44 views

Background correction when reading ELISA with TMB substrate

I'm doing some ELISA development, and I'd like some justification/best practices for background correction. I'm using a horseradish-peroxidase (HRP) detection system along with a TMB substrate and an ...
1
vote
1answer
24 views

How to fix a small pond that has become stagnant?

I'm working in a park and we have a small pond a part of a river system that has become stagnant, mucky and smelly. The river that previously ran into the pond is no longer there and we'd like to be ...
2
votes
0answers
26 views

How to gather life-history traits data on bird species?

I am looking for a data base of life history traits for bird species. Is there such data base? If not, what are your advice on how to collect those data? Is there a handy website that list ...
2
votes
1answer
40 views

How does Celiac's Disease cause people to stop growing?

In all of the sites I've looked on, one of the symptoms of Celiac's Disease is the failure to grow in children. Why would an immune attack against gluten cause stunted growth? Celiac.org states: ...
-1
votes
0answers
35 views

Can Crohn's disease be cured?

Can Crohn's disease be cured? Is there any cure?
-4
votes
0answers
48 views

i am 25 years old and my wife 22 years old and both we have same A+ blood group what about our pregnency? [on hold]

i am 25 years old and my wife 22 years old and both we have same A+ blood group. But, what about when we have kids? will our kids have the same blood group?
1
vote
0answers
20 views

Blood urea nitrogen and usage of proteins?

I have been reading some books and am getting slightly confused. Here is roughly what I have read. The greater the blood urea nitrogen the greater the usage of proteins (since blood urea nitrogen ...
6
votes
1answer
36 views

How does pressure measured by sphygmomanometer translate directly to blood pressure?

As per my understanding a sphygmomanometer when wrapped around the arm and inflated only measures the pressure of the air inside the cuff, doesn't it? How does that translate directly to the pressure ...
3
votes
2answers
110 views

Is there a short-term, very strong anesthetic, which can be blocked/delayed by other substances?

Question migrated from World Building SE. (For fictional use only, of course :) ) I am looking for an anasthetic which fulfills the following criteria: very strong effect, induces a comatose state ...
2
votes
3answers
72 views

What is the difference between meristem and bud?

Keep reading both terms quite frequently while studying plant physiology. I did some research trying to establish their differences and I learnt that meristems are undifferentiated cells that can ...
0
votes
0answers
20 views

View ABI chromatogram plots with python

I would like to view the chromatogram traces from a few ABI (.ab1) files. I would prefer to use python for this, or a function with python bindings, or at least some open source package such as ...
13
votes
2answers
10k views

What is the difference between local and global sequence alignments?

Obviously there are a bunch of different alignment tools out there, and I don't want to get bogged down in the maths behind them as this differs from software version to version. I am aware that ...
0
votes
1answer
28 views

What is the difference between options protein and replication in the NCBI database?

After checking the NCBI help page, I am still unclear about the difference between protein and replication interactions for HIV. ...
2
votes
1answer
46 views

Is the immune system suppressed during sleep?

Of course we have heard that during stress our immune system is suppressed. This leads me to wonder, does the immune system get suppressed when we are sleeping and why? During both these conditions ...
1
vote
1answer
30 views

Blood pressure measurement

When measuring your blood pressure in your arm, when you hear the sound to measure the systolic, is that sound NOT the heartbeat?
3
votes
1answer
39 views

Is pulse rate measurable in the capillary bed and venous vasculature?

Pulse rate is easily felt when gently pressing the arteries in the wrist or neck region (Fig. 1). Fig. 1. Feeling the pulse at the radial artery. Source: Wikipedia Arteries supply the thin ...
3
votes
1answer
16 views

Cellulose acetate membrane filters vs. glass microfiber filters

At equivalent pore sizes and pressures, which exhibits faster flow rates, cellulose acetate membranes or glass microfiber filters? I know cellulose acetate exhibits low protein binding, but what ...
12
votes
2answers
2k views

How was birth control realized in ancient days? [closed]

In ancient days, there were no birth control methods like condoms or contraceptive pills available. How did they control pregnancy?
2
votes
2answers
62 views

What is the cause of colours of nail

Why the nails are of white colour from bottom? then why they are pink and again white in the end?
3
votes
0answers
21 views

Do High Triglycerides Invalidate Tests for Infections?

Blood donation websites tell you to avoid eating fats a few days before the donation, because when there is a lot of fat in the blood, they can't test for infectious diseases and must discard the ...
4
votes
0answers
29 views

Is it even theoretically possible to restore Tiger population to 100,000?

The current global Tiger population is roughly 5100 according to Wikipedia. With habitat destruction and poaching continuing and no effective improvement in conservation, most likely the Tiger ...
2
votes
1answer
47 views

Are there histones present in the cytoplasm?

In this paper the authors depleted core histone heterodimers H3-H4 at 90 % from the cytoplasm of Xenopus oocytes. They state that their concentration is in the order of 6 uM. My question is, are ...
1
vote
0answers
54 views

Do genetic modifications exist to enhance the taste of tomatoes?

GM tomatoes seem less tasty. Has there been any research on GMOs with regard to taste? Can scientists introduce a gene to, let's say, tomatoes, which would enhance the flavour? If not, why?
3
votes
1answer
47 views

Hodgin-Huxley model for a single neuron

I am viewing (through edX ) an introduction course to computational neuroscience. In the second lecture, the Hodgin-Huxley model is considered. I am going over some of the questions and have ...
-2
votes
1answer
39 views

Why do aquatic animals smell so bad? [on hold]

Many have experienced the "fishy" smell prevalent with seafood, but why do aquatic animals smell so bad? Is it because of salt water?
11
votes
3answers
3k views

Why do humans find baby animals cute?

Why do humans find baby animals like cats, dogs, ... so cute? As these are potential competitors (when grown up!) or even natural enemies (like e.g. tigers, leopards, ..), the protection instinct ...
4
votes
4answers
210 views

Why can't you just take a vitamin? Why you need a healthy diet on top of that?

From what I understand, your body needs certain amounts of vitamins and minerals to maintain health. Why can't we just take enough pills to obtain these vitamins and minerals?
4
votes
1answer
34 views

What determines the thickness of Cornea?

In eye-operations such as Lasik and Femto, the thickness of cornea is key decision factor whether the operation is feasible. A normal thickness is between 500-600 µm. Cornea consists of a very special ...
12
votes
4answers
2k views

Help identify this worm-like thing

Many instances of this worm-like creature were found in a water system for a mountain cabin in the Sierra Nevada mountains of the US, in late June / early July. The water system collects water from ...
-1
votes
0answers
47 views

What are the effects of alcohol on Dolphins? [on hold]

I have seen that dolphins appear to use blowfish to get high for recreational purposes. What I was wondering if someone has noted their demeanour while consuming alcohol? In humans alcohol acts as a ...
1
vote
1answer
16 views

Genetic linkage greater than 50 centimorgans

Classically, the linkage between two loci can be measured in centimorgans (cM), which represents the percent chance that these two loci will recombine an odd number of times (generating a recombinant ...

15 30 50 per page