0
votes
1answer
23 views

Reasons people with Down syndrome get fewer cancers?

I'm coming across some conflicting information regarding the correlation between cancer incidents and trisomy 21. I read a report from nature that discusses how Downs are only a tenth as likely to ...
0
votes
0answers
14 views

alternative ways to detach cells other than trypsin [duplicate]

So I have an A549 (rather "sticky" cells, they usually take about 7 minutes to trypsinise) cells and I cannot use trypsin or tripLE as this will skew my ELISA results. I have tried scraping the cells ...
1
vote
0answers
15 views

How to explain Genome, Genes, RNA and protein in one figure to non-biologist?

I have a presentation to do where non-biologist are attending. In order to introduce a little bit my work I have to do a quick summary on genomes. So what is a genome, a gene, an mRNA and a protein. ...
5
votes
0answers
29 views

Why do some vaccines last longer than others?

After reading an answer to the question of How Do White Blood Cells Learn? Or Do They?, I came to wonder something. Specifically, The effect of this is that every new B and T cell that your bone ...
-2
votes
0answers
28 views

Size of the Drosophila melangoaster genome components

How large are: one X chromosome one of each of the major autosome (chromosomes 2 and 3) for Drosophila melanogaster in the following measures? Length of DNA expressed in base pairs e.g. Mega ...
0
votes
1answer
12 views

What are host cellular factors?

With respect to this paper: Global Analysis of Host-Pathogen Interactions that Regulate Early-Stage HIV-1 Replication What does the term "host cellular factors" mean??
0
votes
0answers
4 views

How does a pollen grain travels through the pistil of a flower?

When a pollen grain settles on a stigma of the pistil of a flower, it is gradually guided through the style into the ovary where the ovule resides. I want to know of the detailed mechanism, how it ...
0
votes
0answers
5 views

How much pollen is needed to pollinate a flower?

Assuming 100% of the pollen gets delivered to exactly the locations it needs to pollinate a female flower, how much pollen is needed to pollinate a flower? If it's more than one unit of pollen, what, ...
-1
votes
1answer
60 views

How to get my original research published in the National Center fof Biotechnology Information? [on hold]

Thought I'd ask here. The site is this: http://www.ncbi.nlm.nih.gov/. I want my original research to be published there within the following terms: 1.I refuse to obtain a college degree in a related ...
1
vote
1answer
25 views

Are any biology research journals free to publish in?

The research journals Ive published in require significant financial cost to publish. On top of that many require a membership to the society the journal is associated with, in addition to publication ...
1
vote
1answer
20 views

In which of the following diseases structure of haemoglobin produced is normal but their amount reduced?

The options provided are- Chronic blood loss Sickle cell anaemia Haemolytic anaemia Thallasaemia Transfusion reactions - *Q-15: pg-785; **Review of Medical Physiology - William F. ...
1
vote
1answer
25 views

Are the irises an exact match in a human's set of eyes?

Are the irises an exact match in a human's set of eyes? Assuming the eyes are healthy with 20/20 vision.
2
votes
1answer
23 views

What worms devour the body?

I was reading http://www.webmd.com/skin-problems-and-treatments/acne/adult-10/slideshow-adult-acne which broached comedones, an esoteric word to me; so I thought to look up its etymology which I find ...
0
votes
0answers
17 views

Producing foreign (form another bacteria type) proteins in E. coli [on hold]

Although along with the genes, aren't specific glands or something required too, to produce the thing? No matter what genes we add to humans, human body can't produce some vitamins... I guess ...
6
votes
0answers
31 views

What will happen if a scorpion pierces itself?

If a scorpion pierces itself, will it die or immune to its poison? If it produces the venom its blood should be immune to itself poison.
1
vote
0answers
89 views

Can there be a nervous / psychological control over pregnancy? [on hold]

First and foremost, if you feel intense anger that this question is being asked, I share your anger. Can there be a nervous / psychological control over pregnancy? This seems unlikely but there have ...
0
votes
0answers
12 views

Bacteria can resist topical antibiotics but not compounds?

The excerpt below origiantes from p 2 of 4, but p 4 of 4 reveals the review of the entire articleby Debra Jaliman, MD on April 17, 2014. Usually, topical antibiotics aren't recommended alone as ...
1
vote
1answer
32 views

Examples of extant animals in a submature morphologically unstable evolutionary state?

I'm fascinated by evolutionary theory and the predictive aspect of it-the notion of an animal entering a strongly divergent state of evolution whereby it is evolving into a new form yet remains ...
0
votes
1answer
18 views

How to predict the top microRNAs that bind to 3`UTR of a specific gene

I would like to know whether someone could tell me 1) some of the online programs that will predict the top microRNAs that bind to 3`UTR of a specific gene (for eg-GAPDH). I am relatively new to ...
0
votes
0answers
13 views

Concentration of a vitamin [on hold]

A vitamin B2 solution with unknown concentration have $A_{450}=0,38$. And a standard vitmanin B2 solution with $25$ $\mu$g/ml have $A_{450}=0,72$ Now what is the unknown concentration in $\mu$g/ml? ...
-2
votes
1answer
57 views

What is the nature of plasmids? [closed]

What are the plasmids composed of? Are they composed of genomic or non-genomic DNA? I guess the answer is "genomic DNA" but I'm not sure.
8
votes
2answers
504 views

Why vaccines do not cause bacterial resistance?

Since bacteria can evolve to overcome antibiotic use, why wouldn't be able to evolve to overcome antibody or cell-mediated immunity? Thanks One possible explanation: antibiotics have only one target ...
2
votes
3answers
3k views

DNA is charged negative. Where is all the positive charge in my body?

DNA is charged negative because of its phosphate backbone. Since charges need to be balanced (so that there are no charges building up somewhere), what is the positive charge which neutralizes this ...
0
votes
2answers
28 views

Why mutations in genes involved in general processes like DNA repair increase the risk of developing specific types of cancer?

For example, mutation in MHS2, which encodes a protein involved in the repair of mismatches that occur during DNA replication, dramatically increases the risk of developing colon cancer. (There are ...
8
votes
2answers
184 views

How to find miRNA binding sites on a specific gene?

I am trying to find miRNAs that bind to the 3'UTR of a specific gene. What is the best way of doing that (that is, with a good scoring analysis that is most commonly used by researchers in this area)? ...
2
votes
0answers
18 views

How long can Cholera bacteria survive in a dead host?

How long can cholera bacterium survive inside a dead host? Can they remain dormant in such conditions? BACKGROUND On a hill not far from where I live, there was a hospital operating since 16th until ...
3
votes
2answers
135 views

explanation of meaning of high-throughput

Almost all of the papers about bioinformatics, I faced with the high-throughput word, but I could not find any explanation about it (I think it is so easy to understand and thats why anyone explains ...
2
votes
1answer
45 views

How can TMS induce enough depolarization to cause an action potential?

Creating an action potential needs at least tens of mV potential difference across the membrane to occur. But the membrane is really thin, surely less then 0.01µm (some reference give 25A). Then the ...
3
votes
1answer
20 views

Cellular Respiration/Fermentation Problem Leading to Lack of Energy

A young animal has never had much energy. He is brought to a veterinarian for help and is sent to the animal hospital for some tests. There they discover his mitochondria can use only fatty acids and ...
5
votes
4answers
47 views

Enzymatic error rate

I am aware that each enzyme generate a certain amount of misproducts. This is well documented, for example, for the DNA polymerase. I am interested in enzyme involved in biochemical processes, so for ...
8
votes
1answer
1k views

Can you consider a human as alive, or is it the cells on the body that are alive?

Sorry if this question seems strange, but in the recent time I have been interested in the question of what life is and how you can define life. My question: How long can individual cells live on a ...
0
votes
1answer
19 views

What sort of assay could be used to identify mutants with mutator phenotype?

By mutator phenotype, I mean being more prone to mutations, for example due to mutations in genes involved in DNA repair. I was thinking about exposing the cells to agents that damage DNA (uv light, ...
0
votes
0answers
16 views

How to safely sterilize urea-containing growth medium?

I'm using urea-containing growth medium for experiments with bacteria (1-2 l/day). After the experiment, the growth medium has to be sterilized and disposed. I did this so far by autoclaving, but our ...
26
votes
1answer
15k views

How does laughing gas (N₂O) work?

Laughing gas (N2O), well, makes people laugh. How does just a gas make us do that, there has to be some hormones at work... So, I wanted to know how this works? What is the mechanism?
3
votes
0answers
25 views

How does the value of K determine number of local optima in NK model?

BACKGROUND The NK model of fitness landscape considers N states which can interact with K other states. For example N is the total number of genes in a haploid genome and K is the number of other ...
2
votes
1answer
26 views

What network motifs or other mechanisms can make the expression of a gene invariable to the environment?

Next to double positive feedback loops and chromatin modification, which other mechanisms can make a gene susceptible to a certain environment in one cell-type but not in another?
0
votes
0answers
17 views

Stable transfection

I need to achieve stable transfection of a pCI-Neo plasmid into the genome of a mouse embryo. The most common way to achieve stable transfection is through positive selection, however positive ...
9
votes
2answers
590 views

Are there grass or fiber eating birds?

My understanding, that may be wrong, is that cellulose/fibre has little nutritional value to many animals because it's hard to break down thus making consumption inefficient. However, Ruminating ...
0
votes
0answers
19 views

Why do you feel euphoria when you're almost done with an illness? [on hold]

This may seem like a subjective question but I have experienced euphoria and a sense of joy every time I am on my last day or few days of illness. This usually lasts for the entire day but no more or ...
2
votes
0answers
28 views

Sensitivity of eyes to flashing lights

My eyes are very sensitive to flashing lights - for example I'm always the first person to notice that a fluorescent tube is about to fail because I see it flickering when other people can't. When ...
43
votes
5answers
8k views

Does DNA have the equivalent of IF-statements, WHILE loops, or function calls? How about GOTO?

Does DNA have anything like IF-statements, GOTO-jumps, or WHILE loops? In software development, these constructs have the following functions: IF-statements: An IF statement executes the code in a ...
0
votes
0answers
24 views

Layman definition of genetic polymorphism?

I am reading an article about Genetic Polymorphism and there are lines in the article about genetic polymophism that I don't quite understand like. In this area,there are six different chemotypes ...
3
votes
1answer
39 views

meaning of the “reads” keyword in terms of RNA-seq or next generation sequencing

I'm an undergraduate student at computer science and currently, I'm interested in bioinformatics. Today, I've started to read a paper about clustering and classification of non-coding RNAs can be ...
3
votes
1answer
17 views

What's the maximum pressure inside a bombardier beetle?

This question got me wondering about the pressure inside a bombardier beetle. Lots of articles mention pressure, but don't specify the amount of it: One study records the velocity of the spray to ...
3
votes
1answer
15 views

Telomere and its effect on aging

The cloned sheep, Dolly, was said to have died very soon because the cells used to create it were taken from an adult sheep with an aged telomere. Why doesn't this happen with humans? Why aren't we ...
2
votes
1answer
37 views

Optical density machine name

What is the name of the machine used to measure optical density? We used it in a lab but I can't remember what they called it.
4
votes
0answers
42 views

Time lapse between fresh blood's exposure to air and that same blood turning darker red-brown

For investigative purposes, I'm searching for a tool that can be used as a quick visual assessment of the the length of time that blood has been exposed to air after the blood flow has stopped.. Let's ...
1
vote
0answers
10 views

What is the maximal insert length for PCR based homologous recombination in S. cerevisae

I would like to insert a 6 kbp construct, which I have on a plasmid into the genome of S. cerevisiae. This plasmid was originally constructed to integrate at the HIS locus via homologous recombination ...
3
votes
1answer
31 views

Do our ears or brains gradually adapt to noise pollution?

Having lived in various places all over the world for the past 9 years of my life, one thing stood out to me throughout this time, and now in particular. From a quiet place on the countryside in ...
1
vote
3answers
32 views

If a gene is located on the X sex chromosome does that mean males are either Homozygous dominant or Homozygous recessive and are never Heterozygous?

As said in the title I am a little confused on the Idea of traits located on the sex chromosomes. The example we worked on in class was hemophilia a recessive trait and since it is located on the X ...

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