6
votes
1answer
161 views

Are low-intensity radio-waves carcinogenic?

A recent review article, Oxidative mechanisms of biological activity of low-intensity radiofrequency radiation reached a surprising conclusion our analysis demonstrates that low-intensity RFR ...
6
votes
1answer
142 views

Hill-Roberston effects and effective population size

From this article, first page, middle of the second column: Even if harmful alleles do not become fixed, they can still reduce the efficacy of selection on neighbouring loci through a process ...
5
votes
1answer
383 views

Relationship between nerves and axons

I just wanted to get a realistic viewpoint of our nervous system. I understand arteries and veins, but I wanted to know how similar our nervous system is to that? I understand we have neurons ...
5
votes
2answers
2k views

Are brain cells replaced over time?

You know how your cells die all the time and new ones are made to replace them, so you practically have a new body every maybe 5 years? Many people say you become a completely different person every ...
5
votes
2answers
236 views

Why do small organisms make faster movements than big organisms?

I hesitated to ask this question because it seems so obvious and intuitive. However, I am not able to explain this tendency. Background It seems to me that small organisms make faster movements than ...
4
votes
2answers
97 views

Short, concise, practical manual for doing experimental biology

I am am physical scientist working in biology, and have recently started doing experiments. I would like a manual akin to "Numerical Recipes", but for the lab: straight forward, easy instructions on ...
4
votes
1answer
159 views

How does “inheritance of methylation” of DNA and/or histones work?

What are the current models/ideas describing the mechanisms explaining inheritance of methylation on DNA resp. histone level? Is there evidance of this "setup" information being really ...
3
votes
3answers
146 views

Can antibiotic resistant bacteria compete with normal one in an antibiotic free environment?

The question is based on an intuition that antibiotic resistance can't come along. This mutation will probably make bacteria less tenacious. Is there any research how AR bacteria compete with normal ...
32
votes
3answers
21k views

Why do eukaryotic organisms have introns in their DNA?

We touched on introns and exons in my bio class, but unfortunately we didn't really talk about why Eukaryotes have introns. It would seem they would have to have some purpose since prokaryotes do not ...
29
votes
8answers
525 views

Has there been any observation of species adapting the evolution process?

I am very interested in the evolution of the evolution process itself. There are of course a lot of things that influence how evolution will work, but for this question, I am interested in things that ...
22
votes
3answers
352 views

How crowded is the bacterial cell?

I was wondering what is the protein concentration in an E. coli cell. When studying enzyme kinetics and activity in vitro, I would argue that the substrate and enzyme concentrations resemble those in ...
17
votes
1answer
223 views

Why do you die if you cannot breathe?

I was wondering what the actual reason for death by suffocation is. Obviously it is related to oxygen deprivation. But what is the underlying cause of death? Is it due to insufficient oxygen for ...
16
votes
3answers
2k views

Do animals exist with an uneven total number of digits?

I recently finished reading Contact by Carl Sagan. In the book they talk about a pattern in the transcendental number like pi or e, and comment that it is found in base 10 or however many fingers the ...
16
votes
2answers
6k views

Why is glucose our primary source of energy?

Is there any evolutionary reason for glucose being the "main" molecule used as a source of energy, beginning with glycolysis and subsequently cellular respiration (after being converted to two ...
14
votes
4answers
9k views

Why we have no enzyme to digest cellulose?

As we know, cellulose is the most abundant polysaccharide in nature. Why don't we have any enzyme to digest cellulose?
14
votes
2answers
2k views

How does evolution produce complex organs

I've been wondering lately how evolution manages to produce complex organs. It is pretty obvious to me how evolution would select some minor traits like size, resistnce to illness or climate. There is ...
14
votes
1answer
3k views

Why do some mammals not have testes in a scrotum?

Coming from an evolutionary approach, Is the only purpose of a scrotum to regulate the temperature of the testes? Knowing all mammals are warm blooded, shouldn't all mammals have testes in a ...
14
votes
4answers
1k views

How many human proteins have a solved 3D structure?

I was wondering how many human proteins have a solved 3D structure. Is there a database with only human proteins? I looked at pdb but couldn't find a filter.
13
votes
2answers
776 views

Human disease and associated phenotype database?

Does anyone know of any good databases that contain symptoms for diseases and other ailments in humans? I've tried working with UMLS, but thats been impossible to work with. I've also tried working ...
13
votes
1answer
230 views

What is the prehistory of amino acids in cells?

As a followup to Why 20 amino acids instead of 64? and What is the smallest number of amino acids required for life?, I am trying to understand the prehistory of amino acids in cells. All living ...
12
votes
2answers
437 views

Why Do Most Humans & Cats Have Blue/Bluish Eyes At Birth?

I've read that the eye color at birth for most humans and for cats may not always be the the true genetic color at first. This is due to the lack of melanin in the iris. This makes sense as there is ...
12
votes
2answers
5k views

Do men have significant hormonal cycles?

I know there's a similar question here. But that discussion dissolved into lunar cycle and a correlation with it. I want to find more towards the original question of is there a periodic hormone ...
12
votes
3answers
324 views

When are population dynamics models useful?

When are population dynamics models useful? There seems to have been a lot of research about it, but how does it help? If I need data about how a population will evolve under what conditions, I need ...
12
votes
1answer
742 views

Does electricity cause damage on a cellular level?

As I understand it the mechanism of death when a mammal is electrocuted is that the current disrupts the SAN/AVN in the heart causing it to fibrilate or arrest. That's on a macro scale, however. ...
12
votes
2answers
596 views

Could an “overactive” brain increase the chances of Alzheimer's Disease?

From Raichle ME. 2010. Two views of brain function. Trends in cognitive sciences 14: 180–90: Alzheimer’s disease (AD) is the most common cause of progressive cognitive decline and dementia in ...
11
votes
0answers
173 views

What is the percentage of people living in England in 1500 AD whose lineage is still alive?

This sounds a bit random but it stems from a lecture in statistical genetics which I attended a while ago. We were shown a population lineage graph from which it was clear that most lineages go ...
11
votes
2answers
892 views

Why cancer is not a communicable disease?

I have seen this question where the author is asking a question about infectivity of virus. I wish to know why cancer is not a communicable disease?
11
votes
2answers
1k views

If human eyes watch an area, what's the shape of its capturing shape? Rectangular? Half spherical?

A normal camera can capture a rectangular image. If human eyes watch an area, what's the shape of the captured region? Rectangular? Half-spherical?
11
votes
2answers
584 views

List of np-hard problems in biology/bioinformatics

I'm not sure if this is the right place for this but... I am looking for a list of computationally "hard" problems such that if a problem from this list could be solved effectively, it would be ...
11
votes
1answer
667 views

How do CpG islands remain unmethylated?

In most of the genome CpG sites are pretty much always methylated, but CpG islands are instead often unmethylated. This has been linked to the fact that they often are associated to transcripted ...
10
votes
2answers
254 views

Did Darwin ever reach the conclusion that selection will remove variation?

According to simple models of selection the genetic variance in a population should be reduced by selection. (Fisher's fundamental theorem states that the rate at which a population can evolve is ...
10
votes
1answer
513 views

What is the modern state of the theory of evolution?

When I studied biology at my medical school we used to learn things about a century old: the famous Darwin's voyage on "Beagle" to the Galapagos Islands, the classical triad of his Theory of ...
9
votes
3answers
303 views

Splice in with CRISPR/Cas

I need to splice a gene into a human cell genome, with highest rate possible. I mean, doesn't really matter where the gene enters, nor does it matter if some cells die as a result of this. CRISPR ...
9
votes
5answers
2k views

Is it possible to genetically modify a plant at home?

Would I be able to genetically modify a plant at home? What equipment will be necessary? I think it might be a fun change from the 'norm' of regular hybridisation, to try some inter-family gene ...
9
votes
1answer
1k views

Did the eugenics program in Nazi Germany have a measurable effect? [closed]

Did the killing or sterilisation of people considered as living a "life unworthy of life" in Nazi Germany have any measurable effect on the "average health" of Germany? Is there any statistical ...
9
votes
2answers
402 views

How is human biological clock modelled in modern science?

Im an engineer by education and i program a lot, so the question sounds weird to people from other disciplines. Im trying to better understand the human biological clock. Yet i do not really know ...
8
votes
3answers
687 views

Where does extra blood come from to fill your muscles during exercise?

Let's say I go to the gym and lift some weights an hour. During this time my arms will grow due to the "pump" -- the extra blood rushing in to feed the muscles. For example, I've measured about 2-3 ...
8
votes
4answers
632 views

Looking for a DNA sequence

I am not a biologist. Please pardon me, if my question does not make sense. I am trying to obtain a DNA sequence for pattern analysis in Matlab. I used to generate random sequence ...
8
votes
1answer
222 views

Genetic Drift: Models, assumptions and empirical observations

There two main mathematical models to describe the process of genetic drift are Moran model and Wright-Fisher model. My questions concern the assumptions of these models, the existence of other ...
8
votes
4answers
533 views

Why people like to see pornographic scenes, but do not feel the same about eating scenes? [closed]

This question may seem funny, but I think biology must have good answers. I think no more explanation is needed. I really thought about this and searched for an answer, but there is nothing yet. If ...
8
votes
1answer
463 views

Has any large-scale origin-of-life simulation/experiment been done?

I have been thinking a little about the origins of life, and was further inspired by this question: How did the first self replicating organism come into existence? I can accept that we don't quite ...
8
votes
1answer
134 views

What happens when we know that there is something that we forgot but we can't remember what it was?

I think it happens for everyone that sometimes we go to a room and forget why we went there. Is there any research or article on this?
8
votes
1answer
403 views

How do the pharmacodynamics of the NSAIDs differ and are there “resistant” COX phenotypes?

I know that the non-steroidal anti-inflammatory drugs (e.g., aspirin, ibuprofen, naproxen) affect the enzymes cyclooxygenase (types I and II). Is there any difference in the degree to which these ...
8
votes
1answer
70 views

Downloadable worldwide database of disease statistics?

I am looking for a downloadable database of disease statistics. I have emailed the good folks over at HealthMap, but they haven't gotten back to me yet. As far as I can tell, their data relevant to ...
8
votes
1answer
7k views

Difference between strand-specific and not strand-specific RNA-seq data

I would like to ask the difference between strand-specific and not strand-specific dataset. As far as I know, strand-specific data means that we know which strand the transcript is from. I do not ...
7
votes
1answer
101 views

If so many different hormones/molecules work by activating adenylyl cyclase, how do they have different effects?

It seems that many hormones and molecules work by activating adenylyl cyclase to convert $\text{ATP}$ to $\text{cAMP}$, such as adrenaline and glucagon. Both of these seem to bind to $\text G$ protein ...
7
votes
2answers
174 views

Why did the Brain develop in the front in most organisms?

I was wondering: why most, well, pretty much all organism with a brain have it right in front of their bodies or at the top.
7
votes
1answer
2k views

Why do human eyes glow red on a photo and dog's eyes green?

Previous Research I know that cameras sometimes come with an anti "red eye" functionality that involves two flashes, presumably the second flash coincides with the shutter opening. Question Why do ...
7
votes
2answers
207 views

What does pain look like in wave form?

I am interested in understanding what "pain" and "hot/cold" look like, as far as waves signatures (signal processing) go. My general understanding of how pain (nociceptive pathways) and hot/cold ...
7
votes
2answers
204 views

How was the resemblance between apes and humans explained in pre-Darwinian biology?

Humans and apes have somewhat obvious similarities, these must have been apparent to natural philosophers before the possibility of a common ancestry was first proposed in the mid-1800's. These ...

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