2
votes
1answer
41 views

Does alcohol really do more damage to the body of a child compared to an adult?

Beside the fact that children and teens (people under the age of 18 year) usually have less body weight than the average adult, is there a biologically fundamental difference between the damage done ...
4
votes
0answers
45 views

How does drug-induced photosensitivity work?

Some drugs (tetracyclines, for instance) can cause photosensitivity reactions—that is, some patients become extremely sensitive to the sun, developing rashes or inflammation after spending time ...
0
votes
0answers
14 views

Best articles on Rad51/Rad52

What are the best journal articles to read on Rad51/Rad52 in the context of homologous recombination and cancer?
2
votes
0answers
17 views

Interaction study of oligomeric proteins

I'm dealing with two different protein(say, protein_a and protein_b) which stays in an interacting-oligomeric form in biological system. I have so far successfully been able to purify both the ...
28
votes
1answer
4k views

Why is the brain white?

I have read many articles about how the brain is the most power-hungry organ in any living complex organism, requiring about 70% of it's oxygen supplies in the resting state. Since the usual medium ...
0
votes
1answer
182 views

How long do human egg cell grow up?

I read article about alcohol harm where written that child may bear with birth defect cause mother used to drink alcohol 10 years ago so egg cell stay damages that long. I don't believe that human ...
4
votes
2answers
81 views

Why lab technicians use indirect (antibody reaction) method for diagnosing?

In microbiology we have two types of microbial diagnosis. The direct method is where we detect the invader's DNA, Antigens or culture to see the exact pathogen while the second, indirect, method is ...
1
vote
1answer
29 views

Is the PCT of the nephrons of the kidneys of marine vertebrates to minimize the natural tendency for exosmosis?

For marine vertebrates, the concentration of salts outside their body (in the water, that is) is more than that inside their body. So, there is a natural tendency for exosmosis to occur. To minimise ...
16
votes
1answer
40k views

Can a person really die quickly from biting their tongue?

A common trope in certain circles (like Eastern martial fiction), is someone committing quick suicide by biting his or her tongue. But is this really possible? The internet turns up millions of ...
3
votes
1answer
98 views

What is the C765-Gal4 driver? [closed]

What is a gene driver and what does C765 stand for? Is Gal4 a transcription factor? Source: "Dynamics of Dpp Signaling and Proliferation Control"
0
votes
0answers
93 views

How to get Population Genotype Frequency from 1000 genomes Perl API

Posted a similar question on Biostars but got no response. Not sure if I'm allowed to link to it? Basically I want to pull genotype frequency data for a population group (such as CEU) instead of ...
0
votes
0answers
15 views

Why do we itch? [duplicate]

Here I have a simple question why do we itch? Is it because of some alteration of the skin or just a reflex action by the CNS? I am asking for a reasoned scientific answer to this.
3
votes
1answer
61 views

Are genes uniformly dispersed throughout the genome?

I think that telomeres and centromeres are regions with a very low gene content (= regions that contain few genes). To the exception of telomeres and centromeres, are genes uniformly distributed ...
6
votes
1answer
251 views

iodine: how did they manage without it in old ages? (People who were living far from the sea)

Knowing that today iodine comes either from fish products or (artificially) enriched table salt, how did people who lived far from the sea survive before (especially during the the Middle Ages)? Edit ...
9
votes
2answers
239 views

Cause of hexadactylisim in Amish people

Is it caused by inbreeding of many generations within an isolated population?
0
votes
0answers
76 views

How to mimic / approach some animals/insects' anabolism?

This article states that some shelled animals - spiders, scorpions, crabs, worms and other creatures - have metal atoms in their claws, jaws and fangs. I believe through anabolism, since they eat sand,...
3
votes
1answer
48 views

Why would mutation rates increase in a tumour?

This article describes a tumour: Swanton found that even the primary tumour was surprisingly varied. He found 128 mutations among the various samples, but only a third of these were common to all ...
5
votes
2answers
55 views

Is viral protein expression important for peptide vaccine?

I would like to know if proteins expressed in higher quantities, such as DNA polymerase, would be better vaccine candidates for a T-cell based vaccine.
3
votes
2answers
75 views

Madrid, Noise by the river: Bird or cricket?

I currently live in Madrid, Spain. In July there was a loud animal near the river, in an out of town area surrounded by grassland, with trees along the river. It's continued into August, though it ...
1
vote
1answer
65 views

does phagocytosis dependent on opsonization?

does phagocytotic activity of macrophages and neutrophils depends on opsonization by IGg (antibody) and C3 complex,if it does, so then why macrophages and neutrophils are categorized in Innate immune ...
3
votes
1answer
125 views

If nerve consists of many axons, where are then their soma located?

This question has haunted me for two years. Wikipedia mentions : A nerve is an enclosed, cable-like bundle of axons (the long, slender projections of neurons) in the peripheral nervous system. ...
3
votes
1answer
57 views

Does tremor frequency generally increase as Parkinson's disease progresses?

I've been trying to research this question, but most if not all the on-line journals require costly subscription, and the studies that are posted look at tremor frequency with regards to other factors....
8
votes
2answers
238 views

If Tumors have lots of mutations in them how is it the immune system can't detect them?

If a cancerous tumor has a lot of mutations in them why can't the immune system detect them? If a person has cancer could this somehow alter the person's immune system so it doesn't function ...
1
vote
1answer
229 views

Drinking soda triggers tingling on a tiny spot on my upper back… but how? [closed]

The title pretty much says it all. Yes, I know it doesn't make sense. That's why I'm baffled. For the past week or two, I've noticed that drinking soda seems to cause a tingling/stinging sensation ...
8
votes
1answer
274 views

How do plants benefit from their seeds being buried?

Common planting advice, when starting many plants from seed, is to bury the seed some small distance under the soil. It seems like most plants (at least members of class Dicotyledonae) will grow a ...
2
votes
1answer
30 views

Testing CO₂ for cell culture

I'm am refurbishing some old CO2 incubators. I would like to test the precision of the CO2 sensor. There is a sample port on this incubator. What sorts of methods are commonly used to measure CO2 in ...
6
votes
1answer
7k views

Is consuming proteins different vs. consuming amino-acids and how?

Yesterday I had a discussion with a friend. He said that consuming proteins and amino-acids is different. He said that those who grow muscles would agree on that. I wanted to argue against that ...
2
votes
1answer
54 views

Can stress-induced cortisol reduce diabetes type I?

Let us consider a patient with type 1 diabetes. I think it would be safe to say that diabetes is an autoimmune disease. Now let us suppose this patient comes under stress. As far as I know, cortisol ...
1
vote
2answers
38 views

Is it possible to merge the genomes of photosynthesizing and electron-transporting bacteria to make an electric cell?

I had an idea of making electric current from bacteria. There are some bacteria that can photosynthesize, and some others are capable of transmitting electrons through each other. Is it possible that ...
2
votes
1answer
84 views

How long does it take unused antibodies to clear the system?

Say you have the flu and a normal immune system. Now you're all better but your antibody level is still elevated. How long does it take for those antibody levels to go back to a base value?
3
votes
1answer
547 views

What is this black insect (wasp-like?) South America?

I live in the Pacific coast of South America. Seems to have two wings, like a wasp's. The "tail" is a bit bulky but is only connected to the rest of the body by a thin part. It's black overall. The ...
5
votes
1answer
374 views

Mouse Colony Software

I am looking for a good mouse colony census program that tracks the mice we have in the lab, breeding success of breeders, lineages, multiple user access, etc. Jackson labs has a program that does ...
23
votes
3answers
3k views

Which organism has the smallest genome length?

Which animal/plant/anything has smallest length genome?
3
votes
0answers
100 views

L-tryptophan in mammalian cell culture

Why must the concentration of L-tryptophan be kept to a relatively low level when culturing mammalian cells? It's an essential amino acid, so I cannot fathom why low concentrations as opposed to ...
4
votes
2answers
542 views

How many copies of a gene?

I am studying mathematical models of transcription and translation and I am wondering: In a particular genome, how many copies of a gene coding for one particular protein should one expect? Are they ...
1
vote
2answers
22 views

What are blood group determinants? [closed]

I am trying to understand if they are the same as the blood antigens. The books I have tried to read say something about them being the antigens on the surface of the red blood cell.
0
votes
2answers
75 views

Molecular graphics

anybody know of some great free molecular graphics systems that can allow for PDB code input? I prefer that it doesn't use Java. I also prefer that it is online, although if there is a great system ...
3
votes
1answer
90 views

Is sequencing error a function of the nucleotide being read?

Checking out on Google Scholar, I can see that for Illumina (just to consider one example) the sequencing error rate is of the order of 0.001-0.01 per nucleotide. Talking about sequencing error, let'...
25
votes
1answer
10k views

What do you see when your eyes are closed?

If you are in pitch black and you close your eyes, you sometimes can see strange shapes of various colors. A lot of the time these shapes and colors change as you observe them. This phenomenon still ...
2
votes
1answer
46 views

How do catenanes form when DNA replicates?

So I am taking a course in DNA replication and repair. And we are talking about catenanes forming when DNA replicates (two circles of dsDNA interlinked) How is this possible?
0
votes
2answers
248 views

Binding of Multivalent Antibody to mutiple epitopes?

A multivalent antibody molecule such as Immunoglobulin M Immunoglobulin A etc bind to more than one antigens or epitopes but I am confused about that wheather these multivalent antibodies bind to ...
4
votes
1answer
204 views

Fruit-bearing tree identification

Just moved into a new house in Puerto Rico and I found this tree in the back garden. Can anyone tell me what tree this is, and whether its fruit is edible?
3
votes
2answers
80 views

Why are our bodies created to itch when histamine is released by our immune systems?

Why do bug bites and cuts itch when scratching them clearly doesn't help us survive? Did our early ancestors need to rely on this itching sensation, or is it just that the receptors for itches just ...
1
vote
1answer
46 views

Is there a good site or software to see if a primer pair spans an exon junction?

I am going to perform some RT-qPCR tests to validate an experiment.  I'm currently in the process of ordering primers, and I would like to get them from the Harvard Primer Bank since these have been ...
1
vote
0answers
16 views

How are split inteins joined?

Do they form a peptide bond? Or is it just some affinity/van der Waals interaction? Is the mechanism enzyme catalized? Are the residues/moieties at the join site known? Could they be introduced to ...
0
votes
1answer
130 views

How much penicillinase is needed to deactivate 125mg of amoxicillin?

How much penicillinase is needed to deactivate 125mg of amoxicillin? Penicillinase in penase concentrate from CPC. 20,000 Levy Units/ml/min I need IU of 125 mg of amoxicillin. Please note that the ...
4
votes
1answer
70 views

How many traits can a multivariate breeders equation handle?

The multivariate breeders equation (MBE) by Lande predicts the change in a trait $\Delta \bar z$ (response) as $\Delta \bar z = G \beta$ where $G$ is a genetic variance-covariance matrix and $\beta$...
1
vote
1answer
50 views

How does the MET gene work and what happens when the promoter region gets mutated?

I am doing research on inherited risk of Autism Spectrum Disorders(ASD) due to common Copy Number Variants(CNVs) One of the mutations is the 'CC' variant of Rs1858830 in the promoter region of the MET ...
4
votes
3answers
200 views

Phospholipid Bilayer structural reversal

What would happen if the phospholipids in the phospholipid bi-layer were reversed, the fatty acid tails now facing outwards and the phosphate heads facing inwards? I'm assuming this will not affect ...
1
vote
0answers
28 views

Is a Ribonuclease Inhibitor protein the only mechanism employed by the human cell to protect cellular RNA from degradation by endoribonuclease?

Are there any other methods of protection for cellular RNA from degradation by endonuclease (specifically the Pancreatic Ribonuclease RNase II (Eosinophil-derived neurotoxin) and RNase III (Eosinophil ...

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