0
votes
0answers
25 views

Stem cells and if they can correct a lack of apoptosis

If a cell ,call it C1 has no functioning apoptosis mechanism could a stem cell somehow be 'induced' to be like C1 , at least have the same genome as C1. Then use this stem cell 'duplicate' to ...
2
votes
0answers
74 views

Which method would more accurately help to identify the unknown concentration of a protein sample between the A280 and the Bradford methods?

I quantified my protein using the standard Bradford method and the A280 methods and obtained values that were far off from the theoretical value of the protein of interest, and therefore was wondering ...
6
votes
1answer
710 views

Time lapse between fresh blood's exposure to air and that same blood turning darker red-brown

For investigative purposes, I'm searching for a tool that can be used as a quick visual assessment of the the length of time that blood has been exposed to air after the blood flow has stopped.. Let's ...
4
votes
1answer
331 views

How does aging affect fingerprint?

Do fingerprints change as we grow from child to adult? Most notably, what is the effect of the increase in surface area of palms and fingers on the finger print? Does the finger print simply increases ...
3
votes
0answers
196 views

Why are fingerprints different even in identical twins? [duplicate]

Why are fingerprints different from person to person? It can't be genetics. Even identical twins has different sets of fingerprints. What is the deciding factor that form and shape our fingerprints?
6
votes
1answer
215 views

Is brain transplantation possible?

Many organs can be transplanted nowadays, including the liver, lungs and kidneys. Can the brain be transplanted?
2
votes
1answer
63 views

Metabolism of different saccharides

Learning about carbohydrates, I wonder what the differences there are in terms of metabolism, and overall health between the different types of saccharides. In other words, does the body use ...
6
votes
2answers
114 views

Do variant callers miss rare variants in reference?

Generally variant calling programs (such as GATK-UnifiedGenotyper) look for differences between reference genome and submitted sequence. However, we all know that reference genome consist rare ...
1
vote
3answers
43 views

How do scientists decide which version of a polymorphism is the main one?

This in fact has bugged me for years, but now I finally remembered to ask. I suppose that if one variation is more frequent, it can be labeled as the default, but what about variations that are ...
2
votes
0answers
36 views

Neural correlates of the function of the cardiovascular system?

Are there any known neural correlates of the function of the cardiovascular system? I'm looking for research results that use standard brain imaging techniques (e.g. electroencephalography, ...
3
votes
1answer
169 views

Maximum RPM in zero-g before losing consciousness, spinning head-over-heels

There are more than a few scenes in Gravity that I find dubious. Specifically the ones where people are revolving very quickly, either about their own center of gravity or at the end of a rather long ...
9
votes
2answers
111 views

How well does the radius of a tree correlate with its age?

I'm looking for a cheap non-invasive ways to approximate the age of a tree (a birch). Measuring the radius pops up in the mind as the first alternative. How would one do that? Measure at multiple ...
2
votes
0answers
24 views

What mechanism is responsible for germinating in the right direction (root towards gravity)? [duplicate]

Regardless of the initial seed orientation, the root always grows/sprouts/germinates "towards gravity" (see picture), sometimes curving around in sharp 180°. What is the mechanism responsible for ...
2
votes
0answers
42 views

Protein Design - Target Structure Specification

I'm curious about how protein structures are defined in general, but in particular, I'm wondering how a target structure can be specified without knowing the amino acid sequence. For example, in ...
2
votes
2answers
117 views

DNA barcoding and real-time PCR

I recently read an article on how DNA barcoding was used to identify species present in health products. I also read an article about how Real-Time PCR was used to identify meat species in meat ...
2
votes
1answer
144 views

Biphasic T wave caused by digitalis toxicity

Digitalis is a drug that can be used during coronary insufficiency to increase the strength of cardiac muscle contraction. But when overdosages of digitalis are given, depolarization duration ...
4
votes
1answer
183 views

What actually are thoughts? [closed]

The human brain consists of neurons that transmit impulses like wires that conduct electricity.I am confused about where are our thoughts stored and what really are thoughts? For example if I think ...
2
votes
1answer
1k views

What happens to our umbilical cord internally as we age?

I was always curious as to if or how much of the internal structure or workings of the umbilical cord are still in existence as we age. What happens to it over time? The wikipedia article naval ...
11
votes
3answers
889 views

Do humans perceive temperature or heat-flux? (or both?)

The general understanding is that when I touch an object, I perceive its (relative) temperature. A metal object at room temperature, however, will often feel cool to the touch. This leads me to ...
3
votes
1answer
104 views

Why oxLDL accumulate to form foam cells?

In atherosclerosis, why macrophage store all the cholesterol from oxLDL inside, and turns to foam cell, and not just degrade it and going back to blood? (there are some amount that leave the plaque, ...
5
votes
1answer
96 views

Can we artificially increase human growth using HGH?

Robert Pershing Wadlow was a man who lived in the first half of the twentieth century. He had hyperplasia of his pituitary gland, which caused him over-produce human growth hormone (HGH), and as a ...
13
votes
1answer
1k views

What is the most condensed form of (stored) energy used in biology?

When considering how organisms store energy for later use, I was wondering what substance known in Biology is best for compacting the most energy in the smallest space(volume-wise). With my (limited) ...
1
vote
0answers
22 views

Clumping factor test

I'm come across this question and I'm somewhat confused: In the test for staphylococci, the clumping factor detects: staphylothrombin DNase mannitol fermentation Fimbriae fibrinogen-binding protein ...
1
vote
1answer
126 views

Why is pericardium muscle repolarizated earlier than endocardium? [closed]

I was reading about heat muscle contraction and I read: The endocardium depolarization happens earlier than pericardium , but pericarduim repolarization happens earlier, therefore the T wave in ...
5
votes
2answers
173 views

Where can I find mutation datasets for cancer?

My lab has been using TCGA data (somatic mutations and clinical data) to develop panels of genes and of mutations we expect to see in certain cancer populations. We'd like to validate our panels by ...
14
votes
1answer
300 views

What are the requirements for a stable carbon cycle in sealed “bottle gardens”`?

The most famous example of a sealed bottle garden is David Latimer's bottle with a Spiderworth plant, pictured below, which has been sealed for 40 years. My own attempt at a bottle garden is failing ...
3
votes
1answer
103 views

Clarification on the “orientation” of chromosomal rearrangements

I need some clarifications on the concept of "orientation" in case of chromosomal rearrangements. Given a deletion event on a chromosome for example, is the resulting DNA at the breakpoint always in ...
4
votes
1answer
124 views

Visualising a subset of the tree of life

I understand that many curated trees of life already exist (eg http://tolweb.org/tree/) but is there any website that allows one to input a list of organisms, and then produce the current best guess ...
1
vote
1answer
806 views

What is the present tense verb form of apoptosis?

For example, if I want to say something along the lines of "this signaling pathway causes a cell to go through the process of apoptosis", but I want to shorten the phrase "go through the process of ...
2
votes
0answers
618 views

How can the directionality of a protein structure be defined?

For a DNA molecule, you can define directionality using the convention of a 5'-3' direction on the Sense strand. However, using an N to C convention for a protein doesn't work since the ends may be on ...
4
votes
1answer
125 views

How can a drone be male?

A drone bee is male and is the product of only a queen bee. How is it that the drone bee can be male. I know that a drone is produced by an unfertilized egg, but this does not explain where the two X ...
3
votes
1answer
44 views

Are some virus loads introduced to human cell but never triggered?

Is there a term or any evidence of phage DNA integrating into chromosomes/ DNA but never being triggered? For example, could a virus that affected Neanderthals still infect human cells today but is ...
2
votes
1answer
125 views

Stockholm format to dot-brackets format?

I need to convert all my sequences in a Stockholm format into this: ...
14
votes
2answers
365 views

Can you Identify this Creature?

I was wondering if someone could assist me in identifying this creature. My father found this when he was reading on his bed. At first we thought it was a piece of lint, but then it suddenly moved. I ...
6
votes
2answers
328 views

Do animals exist which have great vision, but see only grayscale?

In computer vision the color information is often discarded, as most object recognition tasks seem to work just as well on the greyscale image (even better, because there is less unnecessary ...
6
votes
1answer
165 views

Do people with congenital analgesia feel cold?

There are a few diseases that cause an insensitivity to pain. This question asks about the relationship between the cold and pain, which got me thinking: Is shivering a response driven by the ...
2
votes
0answers
27 views

background extraction in microscope analysis

I have taken microscope pictures for proteins in HeLa cells, in order to quantify the intensity (immunofluorescence). The proteins are both at the nuclear envelope, and in order to quantify the ...
4
votes
1answer
94 views

What microscope/magnification would I need to observe P. Acnes bacteria?

I am currently attempting to grow a culture of P. Acnes bacteria. Right now, my only hope in identifying colonies of the bacteria in the culture is to use a black light to find colonies that glow ...
11
votes
3answers
196 views

Why is iodine used for metabolic hormones?

Iodine and related biological iodine-carrying hormones are phylogenetically very old, at least according to Wikipedia. Humans use iodine as a metabolic indicator, as do axolotls and apparently most ...
5
votes
2answers
55 views

How and why can cold inflict pain?

I was carrying a can of very cold liquid, had something heavy in my other hand so couldn't switch hands. After a few minutes, I started to feel very intense pain. I was very surprised. cold is just ...
3
votes
1answer
118 views

Expression/Mechanism of ROR1 in healthy tissue

ROR1 is currently under investigation as a therapeutic target for cancer (1). A number of studies show different cancers may have their metastatic potential reduced, or become apoptotic through ...
1
vote
1answer
178 views

What is Trypsin? [closed]

I am currently helping a PhD student in his research lab. We have been using Trypsin for the past couple of weeks but I am unsure of its purpose. I was wondering how Trypsin functioned and what it was ...
0
votes
2answers
68 views

I photographed a couple of butterflies and birds in Argentina but can't identify them. What are my options? [closed]

I photographed a couple of birds and butterflies in Argentina and tried to identify them. I tried online species identification tools, looked in books, and just tried to find pictures on Google with ...
2
votes
0answers
59 views

Zinc and brewer's yeast

I'm hoping for some information relating to yeast nutrition (specifically Saccharomyces cerevisea) in beer fermentation. Zinc is well-known to be necessary for yeast cultures to perform successful ...
8
votes
1answer
2k views

How can Valonia ventricosa cells get so big?

Valonia ventricosa are single celled algae that range between one and few centimeters. In rare cases they can reach sizes exceeding 5cm. They range from grass green, to dark green, and some are even a ...
8
votes
1answer
515 views

Why aren't green eyes more prevalent?

Why aren't green eyes more prevalent, given that the green allele is dominant over the blue one? My understanding is that human eye colour is determined by two genes: 1) HERC2, with alleles Bx, BB ...
2
votes
0answers
37 views

Why can't there be fructification of mycelium in submerged culture?

I am very new at this. I am wondering why fed batch cultures produce a lot of mycelia but no fruit. I thought the more mycelia you had, the greater chance of it forming a fruit body. I am refering to ...
1
vote
0answers
67 views

How to characterise a protein family in a putative genome island?

We have sequenced the genome of 200 bacterial strains belonging to the same species, a swine bacterial pathogen. In a previous work, it was observed that a protein family of adhesins is present in ...
3
votes
1answer
80 views

What are senescent cells doing in our bodies? [closed]

I'm reading a paper that mentioned the elimination of senescent cells delays aging. I'd like to receive more information about it. The Baker study published in Nature demonstrates that targeted ...
3
votes
1answer
34 views

Where do the phosphate units come from when EGF units dimerize?

Upon EGF binding, EGFR units dimerize and cross-phosphorylate. The phosphate groups are transfered to intracellular c-terminal tyrosine rich regions. Where do the phosphate units come from in this ...

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