6
votes
1answer
259 views

Determining if a specific proline is cis or trans in the protein?

While peptide bonds usually adopt the trans conformation, peptide bonds to proline can exist in either cis or trans conformation. The isomerization between cis and trans is slow, and has been shown to ...
2
votes
0answers
143 views

Virucides - Herbal and otherwise, for HHV6 type virus or any inner-cell virus

Does anyone know where I can find a reliable list of virucides (not anti-virus) that can be used by humans? This virucide must be able to affect viruses that are already inside the cells. St John's ...
10
votes
2answers
567 views

Are the inverse problems of Systems Biology impossible to solve?

I have heard Sydney Brenner give a talk (see link below) on how the entire program of Systems Biology is suspect because, according to him, a chap named Hadamard showed that inverse problems are ...
7
votes
1answer
205 views

What preceded ATP synthase?

ATP Synthase is ubiquitous throughout life on earth and so most probably evolved within the last universal common ancestor (LUCA) before that lineage diversified into the various kingdoms of life. ...
5
votes
2answers
2k views

Why does milk contained in cartons of milk expand?

In the morning, I went to the fridge to drink some chocolate milk. At night, when I took out the same carton of milk, the packaging seems expanded, like some kind of air is inside. Explain please !
3
votes
1answer
308 views

How was the diversity between ethanol fermentation and lactic acid fermentation evolved?

Quite simply, some organisms metabolize glucose under anaerobic conditions via Glucose->(2) Pyruvic Acid->(2)Ethyl Alcohol. Some organisms, however, metabolize to lactic acid. When did such a process ...
11
votes
1answer
127 views

How would one calculate the availability of nucleotides to an enzyme?

How would one calculate the availability of nucleotides to an enzyme like a polymerase ? I imagine an answer in units like nucleotides per second per enzyme, but I'm also imagining an answer that is ...
2
votes
1answer
254 views

Fossils of intermediate stages?

If Humans are evolve from Monkeys, there must be stages in the evolution process, when it was 1% human and 99% monkey, 2% human and 98% monkey and so on. This is because evolution was a very slow ...
1
vote
3answers
212 views

What difference does it make in the organism's physiology/metabolism whether oxygen binds reversibly or not?

A follow-up to How does hemoglobin-free blood transport oxygen? I'm unsure about the use of physiology/metabolism in the title there. The question in mind is whether this reversible binding makes an ...
8
votes
1answer
3k views

How does sodium in one's diet affect blood pressure?

Due to high blood pressure, my doctor has recommended I go on a low-sodium diet. So, that got me wondering what it is about sodium that drives this recommendation? What does sodium do to a body ...
5
votes
3answers
143 views

Can genetically modified genes jump to bacteria in the eater's intestine?

The Guardian ran an article a while back talking about GM gene's jumping to bacteria in an eater's intestine. Has other research confirmed this phenomenon?
1
vote
0answers
51 views

The relationship between the currents of intracellular and extracellular ions of a cell

In a cell, assume that only sodium, potassium, chloride and calcium ions can cross the membrane and their currents are: $I_{Na}$, $I_{K}$, $I_{Cl}$ and $I_{Ca}$, across the whole membrane. There is ...
2
votes
1answer
57 views

Diet of free-range herbivores

Giving minimal credence to estimates in popular media of the average biomass of insects/arachnids, etc. in an acre of land, it seems that a "free-range" cow (I don't mean to pick on cows) might be ...
6
votes
1answer
323 views

$S_{0.5}$ vs $K_m$ values in enzyme kinetics

What is the difference between $S_{0.5}$ values and $K_m$ values in enzyme kinetics?
8
votes
1answer
220 views

What hair do aquatic mammals have?

I'm reading an essay on the creating of the Mammalia zoological classification (Londa Schiebinger, The American Historical Review, Vol. 98, No. 2 (Apr., 1993), pp. 382-411). It contains the statement ...
1
vote
2answers
229 views

Effect of extracellular molecules on membrane potential

I am reading about the effect of extracellular potassium and chloride on the membrane potential, and now a question has come to my mind about what would happen if we added some molecules that have no ...
4
votes
1answer
199 views

How does hemoglobin-free blood transport oxygen?

Snails... We have some kind of huge garden snails appearing lately (read since the last 10 years or so). Try as one might, it's impossible to avoid them when driving. These snails do not appear to ...
3
votes
1answer
140 views

Statement about Tropical Rainforests

I made a statement about tropical rainforests, and I want to know if it's somewhat true or not: The soil in tropical rainforests is not exceptionally fertile, because it contains few minerals. The ...
2
votes
1answer
48 views

PGC-1β Sod2 limiters/blockers

I'd like to block a percentage of PGC-1β or Sod2 expression. According to the following paper's figure beta-blockers inhibit some expression of PGC-1α. Are there any medicines/chemicals which safely ...
5
votes
1answer
130 views

What selective factors drove the evolution of lactose in lactation?

As far as I can determine, lactose, and the monosaccharide galactose have few biological uses outside of mammalian lactation. It not only required enzymes for its production, but enzymes in offspring ...
6
votes
2answers
156 views

Do omnivore mammals vary food preferences based on dietary needs?

I'm wandering if mammals that can eat many different kinds of food (omnivores) vary their preference for food not only based on the availability, but also based on dietary needs? I'm looking at this ...
2
votes
2answers
108 views

Is there some branch of biology that deals with the entire organism?

I'm reading about various parts of the human body and brain and started to wander if there's a branch of biology that deals with the entire human? I know that there are branches various -biologies, ...
3
votes
1answer
48 views

mutant down but not out

I am interested in a gene which is null lethal but I need to temporary induce diminished capacity. If a cell is homozygous is it possible to induce heterozygous phenotypes or a partial knockout from ...
10
votes
1answer
158 views

Does stress physically age our body?

Going by the assumption that stress eventually triggers a flight/fight response, and the subsequent realization that flight/fight puts the body in a system of readiness to use it's available resources ...
3
votes
2answers
132 views

What is the biological basis for a human's ability to think clearly and be aware while “fighting/competing”?

I'm interested in learning more about the biological systems or hormones or parts of the brain that affect short term (<15 minutes) ability to concentrate attention on the task and be aware of the ...
4
votes
1answer
224 views

What is the molecular basis of hangovers?

Well, most of us have experienced the wonderful feeling of the dreaded hangover. How does it work exactly? I imagine it has something to do with dehydration but what are the underlying mechanisms? ...
9
votes
1answer
227 views

Can cancer grow forever if supplied with unlimited resources?

If somehow a human could give a tumor unlimited resources, would the cancer grow forever? It seems like it would until it gets so large that it physically affects vital organs. Is what would likely ...
1
vote
0answers
52 views

Does Dorsal Raphe Nuclei firing pattern change in response to voluntary breathing?

I'm reading this paper, which discusses how Serotonin may be involved in motor functions of mammals: 5-HT and motor control: a hypothesis . The paper includes the following diagram of the Dorsal ...
4
votes
2answers
59 views

Is there a circadian component to hunger?

I'm wondering what produces the feeling of hunger in humans. Checking Wikipedia revealed that leptin and ghrelin are two hormones involved. I've also read that the digestive system produces its own ...
11
votes
1answer
3k views

Fish “coming back to life” after being frozen

I've encountered a clip on Youtube showing a goldfish thrown in liquid nitrogen and immediately after to normal water and swimming normally. In the explanation to the clip it says: For everyone ...
2
votes
2answers
131 views

Is better healthcare a bane to the long-term survival of the human race?

The theory of natural selection has it that individuals with better genes tend to survive and reproduce, passing their genes to their offspring. This gradual process results in a population more ...
5
votes
3answers
2k views

Why does so much variation exist within species?

My last phrasing of this question did not go down well, so I will try again. The genotype of species is not always the same. If you ask yourself why not all of these possible expressions except one ...
8
votes
1answer
91 views

Predators faking to be not hungry?

I believe that there are predator/prey combinations where the prey can easily spot that the predator is not hungry and will not try to flee from it. I’m thinking, for example, of gazelles who will ...
9
votes
2answers
300 views

Is there any evidence that a virus can modify human evolution

I was just reading Evolution of lactose tolerance, and in it one line says "But there was a time in human history when our diet and environment conspired to create conditions that mimicked those of a ...
20
votes
5answers
364 views

Are there any substance that are more dangerous at low dose than at higher dose?

It is commonly admitted that The dose makes the poison which means as a person, the more I take a substance, the more risk I take for my health. There is even an indicator called LD50 (see ...
4
votes
1answer
352 views

How useful are vitamin and trace element additions in E. coli culture medium?

In protocols for minimal media for growing bacteria I often see that a vitamin mix or a mix of various trace metals is added. But at least for E. coli I know that those are not strictly necessary, ...
2
votes
2answers
51 views

What do breeders call the effect when a breed resists modification?

It is impossible to breed a blue rose or a cat with a bulldog shape. This is because breeding is limited by gene variations in the population. What do breeders call this effect? UPDATE I guess ...
2
votes
1answer
179 views

Why do the sick and unhealthy trees leaf out first in spring?

It's spring. The time of year that trees start to leaf out. I have been watching them, and noticed an interesting pattern. The unhealthy trees of a species leafs out first. I've noticed this ...
2
votes
1answer
78 views

Why glycoproteins are better than non-glycoproteins in fulfilling biological tasks?

I have just an intuition that the carbohydrate part of glycoproteins help them to fulfil those tasks like in plasma membranes. You can also get many more receptors if you can use carbohydrates too. ...
3
votes
1answer
118 views

An unexpected mushroom in my garden

My grandma is a great fan of mushrooms and knows quite a lot about them. About 10 years ago, she started throwing out mushroom remnants in one special place, in order to grow her own mushrooms. In ...
3
votes
1answer
258 views

Do all sea creatures that have scales have to have fins?

Do all sea creatures that have scales have to have fins? Do we know of any sea creatures that have only scales without fins? I'm especially interested in fish that have scales but no fins.
2
votes
1answer
289 views

Screen brightness for reading in dark room [closed]

While searching online I did not find any conclusive article on whether it is good or bad for one's eyesight to read on a computer screen in a dark room. Most mention that it will cause strain that ...
3
votes
1answer
2k views

Slow-oxidative fibres vs fast-glycotic fibres

Why do slow oxidative muscle fibres contain more mitochondria compared to fast-glycolytic muscle fibres?
2
votes
1answer
56 views

What are the distinctive structural features of single- or double-stranded xRNA, or where can I find them?

I am interested in the structural differences caused by benzopurines and benzopyrimidines at the oligonucleotide level between RNA and xRNA, both in single-stranded and double-stranded form. I am ...
3
votes
1answer
59 views

How are atoms in benzopyridines and benzopurines numbered?

I am well-aware of the numbering system used for the traditional bases, as seen below. My question is how are the atoms in the size-expanded bases seen in xDNA and xRNA numbered?
4
votes
1answer
193 views

How quickly can the human heart rate rise and fall?

How quickly can the human heart rate rise and lower? For example lets say a human heart rate is rested and is at 60BPM and that person is suddenly scared to trigger their fight or flight reaction. ...
2
votes
2answers
170 views

Filamentous algae - what exactly am I looking at?

I have just taken some images with my light microscope at 400x of (what I think is) some form of filamentous algae from a local pond. Now, I think I am looking at a single cell (centre) with some ...
9
votes
1answer
1k views

What determines testosterone exposure in womb, baby's genetics or mom's body?

I read this article which has the following quote: The ratio between index and ring finger is believed to be linked to exposure to the male hormone testosterone in the womb. And I wonder what ...
9
votes
5answers
2k views

Difference between genetic engineering and synthetic biology

I've recently seen the term synthetic biology being used to describe research involving genetic modification of organisms. What is the difference between synthetic biology and genetic engineering? Is ...
7
votes
2answers
113 views

A mathematician's confusion regarding parametric $t$ tests for gene expression data

I'm a mathematician trying to test some things on gene expression data, and I'm thus skimming over various articles such as Sotiriou et. al. to understand what is typically done with such data sets. ...

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