22
votes
1answer
388 views

Phagemid display

If I'm using a bacteriophage for phage display and I'm trying to avoid avidity effects by using a helper phage what would be the best way to maintain a large library size while keeping everything ...
4
votes
1answer
104 views

Question about Monofunctional glycosylases

I am learning about Base excision repair mechanism. I understand the main idea how glycosylases are working, but I am trying to understand this with much more details. I found a paper where they are ...
6
votes
1answer
166 views

What is this snake

I took a picture of this snake in Switzerland (Geneva Area): It looks to be an adder but cannot be sure about which species. In Switzerland we have two kinds of adder: Vipera berus Vipera aspis ...
0
votes
1answer
65 views

What is this discarded exoskeleton from?

This morning I was looking round the garden and found this sticking out of a pit in patch of soil, next to the wall of the house (in a trough sort of thing). I came to the conclusion it must be part ...
2
votes
1answer
92 views

Identifying a spider from my childhood memory

Once, as a child, I found a spider in my parents' garden. I remember catching it in a jar because I thought it looked unusual, but I never figured out what kind of spider it was and unfortunately ...
0
votes
4answers
2k views

Are chromosomes from each parent split between gametes with equal probability (esp. in humans)?

I've recently read a little on Wikipedia about genetics, but I can't find a direct answer to this question. My rough understanding is this: Both males and females have pairs of chromosomes, one ...
8
votes
1answer
228 views

Do ants feel acceleration?

The organ we have to provide us with current acceleration information is quite complicated. Because an ant queen didn't seem to notice when I picked up the bottle she was in, I have a suspicion that ...
3
votes
2answers
125 views

The move from RNA to DNA and the necessity of reverse transcriptase

In this piece about giant viruses and the origin of life, in the context of the move from RNA world to DNA world, virologist Valerian Dolja states: In order to move from RNA to DNA, you need an ...
2
votes
1answer
257 views

How is this yellow bumblebee called that I photographed in New York City?

Does anybody know the name of this bumblebee? (For categorization on wikipedia commons)
3
votes
1answer
587 views

What is the name of this flower with purple leaves and orange inner part in NYC?

I've photographed this flower a few days ago in New York City: Does anybody know the name of it? (and how is the orange part called?)
1
vote
2answers
88 views

How to know if your breathing is normal?

Is it possible for a device to measure how much air we breathe in and out over the entire day and at what rate? I think if we have access to this data we can compare it across people.
1
vote
1answer
94 views

How Ants know about Earthquake?

How does an ant know about Earthquake is it because of an organ or due to other factors?
1
vote
0answers
53 views

Will breathing through mouth result in any disorders? [closed]

My nose is slightly bent. When I was born, I had an issue with breathing. My mom said that doctors had inserted a breathing tube in one of my nostrils. This tube may have caused the deformation. From ...
3
votes
0answers
40 views

DNA barcoding, querry regarding tree based (cluster) methods for species identification

I am working on success rate of DNA barcoding in identification of species using distance and tree based methods. Regarding distance based method, I have used Adhoc and species identifier and ...
2
votes
1answer
84 views

Do Ants have a sense of Direction?

Do ants understand which way is up or down? Could they differentiate between uphill and downhill?
2
votes
1answer
73 views

Converting Ensembl Compara gene tree DNA alignment to corresponding amino acid alignment

I have Ensembl compara gene tree alignments (Compara.gene_trees.57.fasta.gz downloaded from ftp://ftp.ensembl.org/pub/release-57/emf/ensembl-compara/homologies/) in nucleotide format. According to ...
10
votes
2answers
809 views

What happens once a brain is full?

I just read the answer to this question, and it got me thinking... If the human brain (or any other brain) has a finite amount of storage, what would happen once the brain has taken in its maximum ...
1
vote
2answers
59 views

What is the formal terminology for two species that are “close” to each other in a phylogenetic tree?

Take for example the human and the chimpanzee, they are "closely related" species since they are "close" to each other in a phylogenetic tree. However, this terminology seems pretty informal, what ...
2
votes
1answer
73 views

Is it dangerous to eat a mutated eggplant descended from a radioactive ancestor?

What is the risk, if any, associated with eating a 100th-generation mutated eggplant derived from a radioactive ancestor? In another word, is that possible that organic toxin will be produced by the ...
3
votes
1answer
161 views

Remove RNAse from pipettes?

Our lab uses old Gilson Pipetman pipettes. I've been using some for making mRNA by in vitro transcription and started running into RNAse issues. I'm trying to clean everything up, including the ...
3
votes
2answers
90 views

Turning publicly available genome data into proteins

I'm a computer scientist who is starting to dabble with biology. My eventual goal is to model different kinds of cells with a computer program. As of right now, I'm just trying to take some smaller ...
2
votes
1answer
228 views

Development of vitreous humor

I have tried reading about development of vitreous humor but it is all very confusing. When does it first developed ? Does it renew itself ? Please provide reliable sources..
7
votes
2answers
544 views

Which phylum appeared most recently

I'm aware that our earliest records of many major animal and plant phyla come from the Cambrian or Precambrian periods, and I'm also vaguely aware of some of the objections raised with general concept ...
4
votes
1answer
113 views

Are common eye defects inherited?

If one parent is nearsighted and the other is farsighted. One parent developed nearsightedness later in life, while the other was born farsighted and they are both the first ones in their family to ...
2
votes
2answers
68 views

Maintaining purebred pedigrees and how to lessen chance of getting disease?

Many breeds of dogs are known for a high incidence of genetic disorders. German shepherd and Saint Bernard dogs are predisposed to developing a crippling condition called hip dysplasia. Q: What ...
1
vote
1answer
73 views

To what extent is it possible to understand if a bacteria can produce a protein? (in silico only!)

I have to answer a question about a sub-task of my thesis: Can the bacteria X produce the protein Y? I searched of course Google and BLAST. There is no data supporting that this specific bacteria ...
4
votes
4answers
3k views

E-value BLAST cut-off

What is the best cut-off for e-value in BLAST? Some say 0.01 ,others 0.0001? Even BLAST tutorials don't give a very clear idea about which cutoff suits which purpose? Could some experts give me a ...
8
votes
1answer
161 views

A question about the intersection of evolution and thermodynamics

From this 2014 article in Quanta magazine by Natalie Wolchover there is a quote from a physicist with an intriguing idea about evolution: “You start with a random clump of atoms, and if you shine ...
2
votes
1answer
1k views

Lyonization and X-linked disorders?

Lyonization or X-chromosome inactivation is the conversion of all but one, X-chromosomes in Females into non-coding heterochromatin (i.e. deactivated) leading to the formation of one or more Barr ...
3
votes
1answer
31 views

Regarding apoptosis and inhibitors

If there is an apoptosis shut-off mechanism of any kind, one could call it a null-apoptosis mechanism. If this is possible, could there be a null-apoptosis inhibitor? Something that inhibits an ...
0
votes
1answer
101 views

What is the outcome of a human population starting with only 2 individuals? [closed]

Starting with a human population N = 2, is there any way the genetic variability seen today could have come about? I don't know that much about meiosis, but isn't there a very limited number of ...
2
votes
1answer
47 views

Regarding signalling pathways

Do all signalling pathways have something that can inhibit them? If the signal pathway is benefitial and it is inhibited would the inhibitor be caused by a biological problem? Are all inhibitors ...
4
votes
2answers
498 views

Does making yogurt from non-pasteurized milk work against possible disease bacteria?

In the past, when there was no pasteurization, could making yogurt from milk lower the chance of getting infected by bovine tuberculosis (or other diseases from infected milk)? For example, would ...
8
votes
1answer
2k views

Perspiration after drinking water

If we don't drink water for a long period of time(say,10 hours), as during fasting and then when we break our fast by drinking water why is it that our body starts sweating?
2
votes
2answers
1k views

Is it theoretically possible to treat filaggrin deficiency with a dietary supplement?

http://f1000.com/prime/reports/m/3/2/ "Filaggrin is a highly abundant protein expressed in the uppermost part of the epidermis that is critical to the formation and hydration of the stratum ...
15
votes
3answers
835 views

Why do some trees have a life span, while some don't?

I have heard that there is no limit on the growth of trees, but then why do some trees, such as boxelders and poplars, tend to live shorter than redwoods, for example? Some advertisements for improved ...
3
votes
3answers
91 views

Can 'hardware' thermalization explain memory decay?

Often we are able to memorize very precise bits of information (exact addresses, birthdays of inlaws, number of dirty socks under the bed), but over time our recollection tends to become fuzzy. We no ...
1
vote
1answer
47 views

About the quality of microsatellites

I built a script to detect microsatellites in a FASTA file. However, there are thousands of possibilities. So, my question is: what are the markers of a "good" or "useful" microsatellite? - How ...
4
votes
1answer
540 views

Is there any size limit to the amount of information a human (or other) brain can hold

Im not sure how this would ever be tested but is there a limit to how much the brain can 'hold' before it reaches capacity ? I guess this could also be interpreted in terms of memory, as how well ...
2
votes
1answer
90 views

Currency metabolites vs. current metabolites: What's the right term?

I have seen the two terms currency metabolite and current metabolite used interchangeably. Is there a consensus on which is the ...
9
votes
2answers
766 views

Why does Hunger lead to the aggressive behavior?

I have observed that frequently when people are hungry; they tend to get angry more easily on pointless issues. Does this mean that our fight or flight response is more active when a person is hungry? ...
7
votes
1answer
830 views

Yellow/Orange Fungus on Oak Tree

What is the fungus pictured below? The photo was taken October 6, 2013 near San Antonio, TX. I have Googled it and my results suggest Laetiporus root rot (Laetiporus sulfureus). According to this ...
8
votes
2answers
385 views

How do ants sense imminent rainfall?

I have always been told to watch to see if ant-hole mounds are built up as a sign of imminent rainfall. My questions are, if what I have always been told is true, then by what mechanism do ants ...
4
votes
1answer
124 views

Are there any cases of observed extreme speciation [closed]

Is there an observed (direct not indirect) speciation on record showing a species shift within the span of history of recorded science?
12
votes
4answers
9k views

What nutrients can humans absorb in the mouth?

For instance, I realise being able to absorb simple sugars in the mouth is pivotal in the rapid action of oral glucose gel. Thus I was wondering what nutrients in general can be absorbed directly ...
1
vote
1answer
44 views

psychological database with sequenced DNA records

I'm looking for an epigenetic database which includes for each example the psychological history of the persons DNA. Right now I can only find DNA and epigenetic databases. Sadly none of the databases ...
2
votes
1answer
20 views

Question regarding 2 constructs of tobacco plant

Six independent transformation experiments of tobacco leaf explants were carried out using two different constructs - (1) construct I containing only a Hygromycin-resistance gene $(HYG^R)$ as a ...
3
votes
1answer
106 views

Getting xyz co-ordinates from a .map file (CCP4 format) in VMD

I have a .map file which contains x-ray crystallography data of a bacteriophage. The format of the file is CCP4. I can open the file using VMD. However, I am unable to get the xyz co-ordinates. It ...
2
votes
1answer
65 views

Formation of peptide bond..?

Proteins peptide bond is made by condensation process in which a molecule of water is released and according to this process it is not favorable in water systems than how peptide bond is formed by ...
2
votes
1answer
102 views

Is there any research paper state the pros and cons for human to be taller?

Is there any research paper state the physical health pros and physical health cons for humans to be taller? For example, shorter people seems to more likely to get involved in heart diseases and ...

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