3
votes
1answer
32 views

Is RNA polymerase affected by proteins bound to the coding sequence of a gene?

I am designing a synthetic gene construct to express genes in E. coli driven by either Ptet or PLacO. The construct would look like: -Ptet-(Gene1)-PLacO-(Gene2)- I want to express each gene using ...
4
votes
0answers
57 views

Y Chromosome in Ovary Cancer Data

I have been analyzing TCGA Ovary Cancer data. In Somatic Mutation data, there is data of mutations in all the chromosomes (1-22 and X), but amazingly, I have found one (just one) row of Y Chromosome ...
9
votes
1answer
214 views

When do plasmids replicate relative to its host cell cycle?

For plasmids is so much shorter than their host cell's genome (about 1/1000 in my case), it will take only 1/1000 time for it to replicate. With respect to cell cycle, when will that replication ...
3
votes
1answer
79 views

Mammal vs Placental Mammal

So for Google Earth Day's quiz I ended up being a "Pangolin." Turns out I had no idea what it was so I looked into it and honestly it reminded me a lot of an Armadillo. So I decided to find out the ...
5
votes
1answer
53 views

what is linkage disequilibrium supposed to measure?

During reading about genetics I came across with the term of linkage disequilibrium, and I do not really understand what it supposed to mean. What is linkage disequilibrium? My current understanding ...
9
votes
1answer
171 views

What are the survival limitations of alcohol?

This question was inspired by watching one of the Pirates of the Caribbean movies; particularly where Jack Sparrow allegedly survives on a desert island by finding an unlimited supply of rum. I've ...
11
votes
1answer
141 views

Biostatistics: Pollen dispersal directionality

What Information am I looking for? Think about a tree that is sending pollen all over the place. Because of wind, most pollen grain will go toward one direction. Imagine, we split the 2D area around ...
2
votes
1answer
280 views

Is cysteine deficiency possible?

Is there such a thing as cysteine deficiency in humans or other mammals? What effects would such a deficiency have? As I understand it, most cysteine for humans comes from dietary sources, though it ...
4
votes
2answers
71 views

Does the body have a gate control for pain

I understand it is not the most accurate source but I recall a House episode where he claimed the body had a control mechanism for pain in which only the most painful thing was felt. Is that true? and ...
2
votes
1answer
84 views

Modeling inclusive fitness

Consider a population of two altruist with coefficient of relatedness $r$. The average inclusive fitness of this population will be $w_{0} + br -c$. Like in this example, assignment of inclusive ...
2
votes
1answer
53 views

Help reading gene markers

I'm sorry if "gene markers" is not the correct word. An edit could be appreciated but I don't study in an English speaking country unfortunately. Question overview: In a family, there is a genetic, ...
2
votes
2answers
143 views

Help reading chromatogram

A genetic variation is found in this chromatogram: It says that the "reference sequence" is the top line and that I can use the general genetic code to find the reading frame. I can see that there ...
2
votes
2answers
132 views

Does the biosphere have infinite resources and are they infinitely renewable?

Does biomass represent all of the resources of the biosphere and therefore it would be theoretically infinitely renewable (as long as we have the sun) since all the biomass is part of the carbon cycle?...
5
votes
1answer
66 views

Do non-enzyme catalysed reaction pathways exist?

Can their be a kind of chemical reaction pathway in a cell, that is catalyzed or regulated but NOT necessarily by enzymes? I could not find anything on Google. I have almost no background in biology, ...
4
votes
1answer
240 views

blue/white screening - results are opposite as expected

We inserted GFP-gene into plasmid Bluescript SK+, transformed E. coli with this construct, and then plated on an agar plate with Ampicillin and X-gal to do a blue/white screening. We got blue colonies ...
14
votes
1answer
745 views

What is the magnification necessary to see pond life

My daughter is 5 and wants to learn about Biology. I thought a great start is to see life from pond water through a USB microscope. It would be great if she could see organisms like amoebas, ...
2
votes
1answer
57 views

What does it mean when a protein has a different excitation spectra than wildtype, but the same emission spectra?

We have a GFP mutant that displays a different excitation spectra with emission at 510nm than the WT. However, their emission profiles with excitation at 490nm are the same, and we do not observe the ...
4
votes
1answer
2k views

Does DNA polymerase always go the same direction?

I read that mutations are more likely to occur on "the strand that DNA polymerase replicates discontinuously". Does DNA polymerase always go replicate the same strand discontinuously, and if so, how/...
5
votes
1answer
81 views

Do we instinctially interpret birdsongs as a sign that there are no predators present?

I was outside today thinking how nice it was to hear the birds back from winter when I started thinking about the fact that we like bird song. It makes us happy in a very basic level, the sort of ...
3
votes
1answer
190 views

Why do spiders make their web near the ceiling and near a light source?

Why do spiders make their webs near the ceiling and near light sources ? Is their an advantage for spiders in doing that? For example do they catch more insects when their web is near a light source ...
3
votes
1answer
68 views

Applying kiwis on gelatin

Kiwis have the enzyme actinidain. This enzyme will break the peptide bonds from the gelatin. Making gelatin with raw kiwis will not work, because the peptide bonds in the gelatin will be broken down. ...
5
votes
1answer
211 views

Help me identify this insect

Over the last week or so as warmer weather has arrived, I've noticed small insects crawling around in the bathroom. I'm located in western Europe. They are perhaps 1mm in length, quite difficult to ...
1
vote
0answers
22 views

OCT-1 transport in Enterocytes [closed]

Does Oct-1 transport lactate or any of its products and in which direction (intracellularly to extracellular, the opposite, or inter-nuclear). The literature talks about Oct-1's role in neuronal ...
2
votes
1answer
370 views

Why are clementines easier to peel than oranges?

In my experience, clementines have been significantly easier to peel by hand than and orange. The skin of the orange seems to cling to the rest of the orange much more so than the skin of the ...
6
votes
1answer
952 views

How does the brain cool itself?

Thoughout life everyone tells you that brain is essentially a computer but just like computers your brain would create immense amounts of heat by being in use, so if that's the case how does it cool ...
2
votes
1answer
152 views

“bead” on a string theory of genetics, source?

Thomas Hunt Morgan was a pioneer in genetics and proposed the now false model of genes being "beads" on a string. These beads being indivisible and responsible for a single phenotype, if I understand ...
5
votes
1answer
198 views

Why do we get tired [closed]

At the end of a day full of work, it is general for people that their eyelids start to feel heavy. Laziness takes over and we begin to yawn. We all know that we're tired at that time, but why people ...
1
vote
1answer
51 views

What are the factors on which protein-protein interaction depend? [closed]

Does protein-protein interaction only happens when one of them is basic and the other acidic? Do protein interactions also depend on the protein structure? Are there more factors?
3
votes
1answer
104 views

DNA length and annealing kinetics

I have a mixture plasmids and undesired short linear fragments that share the same sequences. During denaturation and annealing, I would like the plasmids to 'find each other' before annealing to the ...
2
votes
1answer
235 views

If oxygen deficiency is bad even for a short while, why do people swim?

This may be trivia to many of you. Textbook says the oxygen deficiency, even for a short while can injure our cells. Then why do people go for sports like swimming? (where rhythmic breathing is ...
0
votes
0answers
42 views

Cell energy consumption and food intake

I am wondering if each cell in human body starts consuming ten percent more energy, how much food one has to consume compared to normal intake?
1
vote
0answers
59 views

If I fall into a pond with an algal bloom, could I die from the cyanotoxins? [closed]

Suppose I fell into a pond with an algal bloom, and swam in it for a bit, but did not ingest any of the pond water (this is a hypothetical btw). Some algal blooms are harmful, containing natural ...
8
votes
5answers
515 views

Book/source for learning bioinformatics, focused on genomics?

Does anyone know of sources for learning bioinformatics, focused on genomics? I would like to learn alot of skills I could apply potently in the workforce if I ever became adept at the fields. My ...
2
votes
4answers
601 views

Why *morning walk*?

My PT teachers professes working-out/training in early morning hours is the best time to do so, a quick search on benefits of morning walk (or some similar phrase) reveals a lot of information which ...
2
votes
1answer
102 views

Does creatine-phosphate (CP) supplementation regenerate NADH?

I have the following facts: It is possible to convert ATP <-> creatine vice-versa. (ref - non scientific) CP supplementation protects against metabolic syndrome. ref1 ref2 Fructose digestion ...
1
vote
2answers
1k views

Did cats evolve from monkeys ? or vice versa?

Did cats evolve from monkeys ? or vice versa ? How similar are the genes of cats and monkeys ? What is the proof that they are related or that they are not related ? Most monkeys climb in trees and ...
0
votes
2answers
45 views

Do sodium channels keep renewing themselves with new subunits made by genes?

genes make alpha beta gamma subunits (proteins) to be used in making sodium channels... If I understand correctly? And so, since the genes keep making those subunits, does that mean new sodium ...
11
votes
1answer
1k views

Why can I see a light flicker when it's in my peripheral vision?

When I'm looking at an old CRT monitor or a worn fluorescent lamp, but not directly in the center of my gaze, the light from it seems to flicker. When I focus my gaze onto the monitor or lamp, the ...
4
votes
0answers
53 views

Which sequence assemblers I can use to compare different paradigms?

I'm a high school student whose interested in bioinformatics. Therefore I chose a project which I study Sequence Assembly. My main goal is to compare different paradigms (Greedy, OLC, De Bruijn). I ...
1
vote
1answer
119 views

Is it possible to knock out a gene in adults?

gene knockout is mainly used in creating newborn animals... right? Well can you do it to already-adult animals or humans so that they themselves would experience change in their body and not just ...
0
votes
1answer
37 views

Literature that demonstrates organisms have a competitive advantage in numbers

I'm studying two bird populations that are competing against each other for a resource: Population A and Population B. Population A is present in much higher numbers than Population B, and as a ...
2
votes
1answer
50 views

What is the most reliable tumour suppressing gene for NSCLC?

I was looking at some tumour suppressing genes that can be helpful in diagnosing lung cancer (particularly NSCLC - Non-small-cell lung carcinoma) at an early stage. I came across a few such as p53, ...
5
votes
2answers
1k views

What has caused life to choose this unfathomably tiny subset of all possible proteins?

I wonder why life uses the particular proteins that it does, about 10^6 different proteins, I think? Evolution cannot explain it because the number of possible proteins is far far too large to ever ...
3
votes
0answers
24 views

Is emergence connected to nature's transition between fractal regimes at different size scales?

A fractal algorithm like Mandelbrot is self-similar in all size scales. This is not the case in nature. A tree is fractal in the sense that each branch is similar to the tree as a whole. But that is ...
1
vote
1answer
47 views

Which monkey species features two distinct male phenotypes?

I remember coming across a popular science article years ago about a monkey species which featured two male genotypes: the first were good looking males who acquired social status (as alphas or betas) ...
5
votes
2answers
184 views

Non Coding DNA and its effect on evolution

I had a discussion with a friend of mine; from his understanding, bacteria and other small organisms have higher amounts of "coding" DNA and, as such, are able to evolve much faster than organisms ...
1
vote
1answer
80 views

Alder Tree Root Nodule Origins?

I recently found out that alder trees have root nodules which contain nitrogen-fixing bacteria and that alders are primary colonizers in primary succession. That leads me to this question: since there ...
0
votes
1answer
59 views

Formation of life on other Planets [closed]

At the present time it looks as if there is no other life in the Universe other than here on Earth . If this is true then why didn't it occur anywhere else ? Is it possible for something to happen ...
5
votes
1answer
2k views

What's a mouth ulcer/canker sore “made of”, and why do they develop?

Mouth ulcers are red/white rings with a crater. They are sore and last for 7-10 days. What I want to know is what they are 'made of' - i.e., what is the ring filled with, and why is the centre crater ...
6
votes
2answers
207 views

Latency differences between our senses

I would be interested in knowing how long it takes between the moment something touches our skin and the moment something is activated in the brain. Also how long does it take in total until we ...

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