1
vote
1answer
86 views

Where can I find the metabolic network for the human erythrocyte?

Where can I find the metabolic network of the human erythrocyte (red blood cell), in SBML format? The red blood cell metabolic network is a model that's usually employed in the literature [see refs ...
0
votes
2answers
208 views

How to determine the actual flux in the human metabolic model of a cell line?

The problem to be solved is to determine what the flux values are for the different reactions in the human metabolic model. As far as I understand, a good way to do that would be to use gene ...
0
votes
1answer
331 views

What is splice junction pairs?

Splicing is a modification of pre mRNA when all introns are removed and exons are joined. What is a splice junction pair? It is two exons which connected together?
1
vote
3answers
411 views

What would happen if you combined the world's deadliest diseases & viruses?

What would happen if you took the deadliest diseases/viruses in the world and combined them in a single medium (a solution of water or a test subject)? Would the strongest virus defeat the rest or ...
1
vote
1answer
73 views

Is the Andraka pancreatic cancer test real?

In the wikipedia article about Andraka's pancreatic cancer test there are some controversial statements. On one hand there are many glorious words about the method, also some awards, also some ...
4
votes
1answer
174 views

Does playing music during sleep actually suppress rather than rouse the brain?

I've long been interested in the effect of music/sound on dreaming, and even built 2 apps that play music during REM period. Now I'm looking at this article about FMRI studies of a sleeping brain, and ...
2
votes
1answer
87 views

Does this equation have a typo? (Systems Biology, singular value decomposition) [closed]

I'm reading a systems biology paper, and I'm suspecting there's a typo in an equation, but I want to make sure. The article is "Systemic metabolic reactions are obtained by singular value ...
2
votes
1answer
1k views

Identification - What kind of animal leaves these tracks?

I live in the suburbs of Washington DC where it recently snowed. I was admiring all of the tracks left behind by wildlife of all kinds when I came across these prints, that I was unable to recognize ...
-1
votes
1answer
63 views

Late control mechanisms of blood pressure (arterial) level? [closed]

I first covered the fast and moderate control mechanisms which I think are Fast control: Baroreceptive reflex (tonus), Chemoreceptive reflex (CO$_2$). Moderate control: Bicarbonate (ECF), ...
2
votes
2answers
101 views

Why do people use anti-inflammatory drugs?

Why people should take anti-inflammatory drugs, when inflammation is a physiological way to defend our organism?
1
vote
1answer
87 views

Do “transcription factor binding site” and “operator” mean the same thing?

Can the terms "transcription factor binding site" and "operator" be used interchangeably in all contexts when referring to a DNA sequence, e.g. regardless of a cell type, whether or not the binding ...
0
votes
1answer
2k views

Which processes are during the latent period of ventricular contraction?

The latent period is the time between the start of depolarisation and the start of contraction. I know that the contraction of ventricles starts after sufficient influx of Ca2+ and threshold ...
1
vote
1answer
35 views

Dinuclei cellular mechanism

I am no biologist, but I have this question buzzing in my mind. It's a matter of curiosity What happens when two nuclei occupy the same cell? Would we expect the embryo (if it lives) to have complex ...
0
votes
1answer
174 views

vestigial structure question

If a species has a vestigial anatomical structure that it no longer uses, would you expect this structure to disappear over many generations through the action of natural selection? Always, sometimes, ...
4
votes
2answers
174 views

How can I fetch nucleotide sequences based on ENA accession numbers and positions?

I have a list of ENA accession numbers and a start and end position in each sequence. In the end I want to align all those sequences, but first I have to fetch them and the list is too long to do that ...
1
vote
1answer
115 views

Is end-systolic volume (ESV) the same as residual volume?

I am reading this site and my study materials. The end-systolic volume (ESV), 50-60 ml, is the volume of blood found in ventricles after systole and contraction of ventricles. I think ESV is the same ...
2
votes
1answer
117 views

Cloning of a sheep.. Dolly?

Dolly the sheep was a clone. When she was born she was eight years old on her 1st day of birth, her mother (from which she was cloned) was also eight years old. What is a molecular reason behind this ...
8
votes
2answers
2k views

Why is the number of PCR cycles limited?

I've been told that the maximum number of cycles in PCR is between 20 and 30. Is this true, and what are the reasons for this limitation?
1
vote
1answer
44 views

Book on yeast reproduction, evolution and on the use of yeast as model organism

I am looking for a good book in: Yeast reproduction mating types Recombination mating type determination mechanism Yeast evolution Yeast as model organism and its use in experimental biology It ...
1
vote
0answers
26 views

How are lophotrichous flagella of helicobacter pylori produced?

I am thinking the mechanism is something like first adhesins (mucinase). Howevever, this does not seem to be enough. How are the flagella of H. pylori produced?
1
vote
1answer
75 views

Evolution, self organization and neuroscience

I have rudimentary knowledge of evolution, and biology in general, so bear with me if this question is a bit naive. Let's say we have a particular trait, like highly sensitive peripheral vision. ...
2
votes
2answers
257 views

Why are transcripts translated from 5' to 3' direction?

What is the mechanism? In other words, how does the tRNA know whether the codon is in 5' to 3' direction? I also heard that anything that is translated from 3' to 5' direction is degraded. Is it true? ...
1
vote
0answers
38 views

How far in evolutionary distance is the P-distance estimator “accurate”?

I'm reading Yang's computational molecular evolution and in the very first chapter it says the P distance is a "simplistic distance measure" between two sequences. It is the number of different sites ...
1
vote
1answer
17 views

Do Yersinia genus spp have anything movement factors?

It can spread in blood (Type III secretion system -> apoptosis). I am interested if there is any others ways to move. Do Yersinia spp have anything virulence factors to move?
2
votes
1answer
61 views

2 blue eyed children

My husband had light brown eyes. His father had hazel and his mother, light brown as well. His younger brother however, has blue eyes. Both my children have blue eyes. Is this possible? I thought once ...
1
vote
1answer
73 views

Pseudosexual reproduction

Research projects with artificial life generally use creatures that are haploid. The offspring randomly inherit some genes from one parent, and some genes from the other parent. Q1: Are there any ...
-1
votes
1answer
806 views

I don't wash my hands and never get sick. Any theories? [closed]

I have only been sick a few times in my life(I'm 21 and probably 3-4 times) and even when I am sick I don't feel that bad and I am over it within a day or two. My family has always given me slack for ...
6
votes
1answer
73 views

Healing rate of cut while suffering from a cold

I recently cut my finger fairly deeply with a box cutter and had to have it stitched. During the healing process I contracted a strong cold/mild flu (a sore throat and runny nose with a high fever, ...
3
votes
1answer
130 views

What is lack in sense of smell called?

People who lack the sense of hearing, vision and speaking are called Deaf, Blind and Mute. But what is the person called if he/she lacks the sense of smell? Is there any case like that?
1
vote
1answer
27 views

To understand clearly extraintestinal diseases

Extradistestinal disease seems to prefer to "bowel" diseases, I think this is about diseases outside gastrointestinal tract so stomach. Consider diseases ulcerative colitis and Crohn's disease ...
1
vote
0answers
34 views

Is there a homeostatic setpoint for number of hours of sleep required by a human?

I've heard this TED.com talk about dieting and it mentions that there's a very definitive setpoint within the human brain about how much a human should weight. The speaker mentions that after as much ...
1
vote
1answer
322 views

why can't we digest cellulose [duplicate]

I have a very tricky question....all the veg and fruit cells contain cell wall and it is made of cellulose when we eat how our body digest though we don't have the enzymes to breakdown 1-4 beta ...
1
vote
1answer
31 views

Correlating Ki values of pesticides to bacterial growth

Four pesticides P1 to P4 are reversible inhibitors of an enzyme E that is essential for the growth of a bacterium B. Their Ki values are given in the table below. Each of these four pesticides ...
1
vote
0answers
50 views

Cambrian explosion and evolutionary arms race

I've seen many times mentioned in textbooks and popular articles that a reason of the Cambrian explosion is an 'evolutionary arms race' between predators and prey. But this isn't really a sufficient ...
5
votes
2answers
315 views

Do we have enough diversity of antibodies to overcome almost any antigen?

I always wonder about the capability of diversity of our antibodies. Do we have enough antibodies to fit to every kind of molecule? Wont't it be easier if our antibodies are like clay and can be ...
1
vote
1answer
80 views

Colchicine addition to cells

When is colchicine added to dividing cells for karyotype studies? I know that colchicine inhibits polymerization of microtubules. 2 So, why should it stop the cell cycle at metaphase when ...
0
votes
2answers
48 views

Is there any format for official Physiological/Medicine answers? [closed]

Assume you have an exam which has 5 extensive questions and 60 minutes. You do not have time to cover most if you write everything in essay format. If you start to write essays, you do not really have ...
1
vote
0answers
33 views

water stress expression markers in arabidopsis thaliana

So far I found papers that show studies using RNA arrays on whom they categorized water stress gene markers in root. Water stresses were reproduced by different protocols (manitol...) but always on ...
13
votes
4answers
35k views

What is the armpit hair for?

Modern human beings, especially women, cut their armpit hair. It seems to me the armpit hair is trivial/useless. Shortly speaking, what is the armpit hair for?
2
votes
2answers
184 views

Do humans have a “dominant” neurotransmitter system/sensitivity within their brain?

I've recently heard a podcast, in which Dr. Helen Fisher suggests that there are "4 broad personality types", and each one is associated with a particular neurotransmitter: The corresponding ...
0
votes
2answers
48 views

about the direct intervention of a child's gender

Can we determine the gender of a child now,I mean,not randomly? There are equal amount of sperms with X chromosome and Y chromosome. Can these two kinds of sperms be distinguished easily? If yes,we ...
2
votes
2answers
244 views

Why don't plants get sunburned?

I just saw a video about the biology between sunburn, UVA and UVB and the different things we know about sunburn in humans. ( http://www.youtube.com/watch?v=ZSJITdsTze0 ) I wonder what keeps plants ...
3
votes
2answers
434 views

How does sequence independent single primer amplification work?

I'm having difficulty finding an explanation of how single primer amplification of DNA works in the literature available to me, can anyone explain the methodology and what it accomplishes?
2
votes
1answer
111 views

Rate of Evolution of population of long lived individuals

Is it necessary that rate of evolution of longer lived trees will be lesser than that of annuals ? I understand that new individuals will come up faster in annuals and it may adapt to varying ...
2
votes
3answers
253 views

What do you see if you look at your own retina with the same eye? (optical feedback)

When you record a video while pointing the viewfinder towards the screen showing a live preview you create optical feedback: video example. An anoalogous effect occurs when you turn your microphone ...
2
votes
2answers
969 views

Are humans an eusocial species?

In the evolution of sociality among animals, different degrees are acknowledged. Some species present overlapping generations, some division of labor, and the minority present reproductive division. ...
0
votes
1answer
46 views

Which processes are included in the process called cells eating themselves?

I am reading about atrophy and I am thinking to which processes the phrase cells eating themselves refer to. Cells need something to survive these difficult times. To decrease protein synthesis ...
2
votes
1answer
48 views

Does Sirtuin protein family Sir2 work in low-calorie diet mostly?

I am reading about the protein family in relation to the prolongation of cell life. It is known that Sirtuins have been implicated in influencing a wide range of cellular processes like ageing, ...
5
votes
1answer
65 views

What method would you use to genotype SNPs in low quality samples?

What method would you use to genotype SNPs in low quality samples? I ideally want to genotype hundreds of SNPs in hundreds of scat samples (very low amount of target DNA, potentially degraded and ...
2
votes
1answer
91 views

Should I design a primer to detect virus based on NCBI genebank?

When I searched HIV on NCBI gene bank, I found 2 results from 1997: http://www.ncbi.nlm.nih.gov/genome/?term=HIV. HIV can change every day, so I think the sequence from 1997 is not useful. Is it?

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