1
vote
1answer
55 views

Is there a scientific name for the field of study focusing on the hemispheres of the brain and their control of opposite sides of the body?

I'm assuming this field of study would focus on motor controls, movement, and exercise, but it could also focus on activities which strengthen the corpus callosum or stimulate a specific half of the ...
0
votes
1answer
145 views

Gene pool simulation [closed]

this simulation, you sampled the gene pool without replaceing beads in the beakerafter you drew each one. Thus, f(A) and f(a) in the gene pool changed slightly after each bead was drawn. For example, ...
3
votes
0answers
290 views

Do Asian women have more difficult births than Europeans?

I recently heard a claim that Asians in general have more difficult births than Europeans. Is this true? I have found a few studies(1,2) on the effect of ethnicity on birth outcomes but they seem to ...
1
vote
1answer
86 views

How to parse SCOP parseable files PDB residue identifiers?

I am trying to parse the SCOP parseable files, specifically dir.des.scop.txt ver 1.75. But, I have been facing problems with the PDB residue identifiers in the file. This is a tab limited file and the ...
3
votes
1answer
39 views

What is the genetic distance where linkage can be ignored?

I heard several times that two SNPs, that have at least 1'000 nucleotides between them, can be seen as 'unlinked' due to frequent recombination events. I also once saw a paper showing a graph "degree ...
2
votes
2answers
2k views

Explanation of the terms “downstream signaling” and “upstream signaling”

In molecular biology, what's the meaning of the terms "downstream signaling" and "upstream signaling"? What's the difference between them?
1
vote
1answer
81 views

Why are new vessels more permeable in microvasculature?

I know for microvasculature New microvasculature (arterioles, venules) are always more permeable as they lack pericytes. and then I have this sentence about new blood vessels (not specific) ...
1
vote
1answer
35 views

What are the movement mechanisms of thrombus?

I am thinking how thrombus (veins, arteries and heart) can move. Secondary mechanisms come to my mind only: some enzyme which lyses it, probably adhesion mechanism. Blood circulation (flow rate) ...
3
votes
1answer
246 views

Benefits of CLARITY?

What are the benefits of CLARITY over this technique that was published more than a year earlier? Of course the second technique needs a fancier microscope that is likely more expensive and requires ...
0
votes
2answers
140 views

PAH gene mutation

Analysis of the DNA of the Phenylalanine hydroxylase (PAH) gene in a patient with phenylketonuria revealed a mutation in the protein coding region whose predicted effect would be to replace the amino ...
1
vote
1answer
86 views

Diffusion of FAD+

Why is NAD+ free to diffuse within the mitochondrion whereas FAD+ is not ? What biochemical properties cause this difference ?
0
votes
2answers
86 views

Why is succinate dehydrogenase attached to the inner mitochondrial membrane?

Succinate dehydrogenase is attached to the inner mitochondrial membrane.All the other enzymes of the Krebs cycle are located in the matrix of mitochondria. What is the biochemical reason behind ...
3
votes
1answer
89 views

Comparing SIFT and PolyPhen to other methods

I'm looking for a database of nsSNP (non synonymous single nucleotide polymorphisms) and their effects. As I understand, the common methods to predict this are SIFT and PolyPhen, and I want to compare ...
1
vote
1answer
485 views

basic programming and bioinformatics [closed]

As a molecular biology graduate student I have decided to learn some basic programming and bioinformatics since everybody says that it is crucial. For example, what would you learn if you need to work ...
1
vote
1answer
56 views

RNase and EtOH issue

I work with RNA and I have some RNase issues. For example I am using RNeasy mini kit and at one step I use 100% EtOH. It does not say it is RNase free or not. Does absolute EtOH inhibits or removes ...
2
votes
2answers
131 views

Is there any evidence of increased life expectancy for animal species?

Life expectancy for human has significantly increased during the last century or so. We all know that there are many reasons that are not linked with "evolution", but I am wondering if such change in ...
0
votes
1answer
105 views

calculate the number of heterozygotes [closed]

The ability to taste PTC is due to a single dominant allele "T". You sampled 215 evolution students, and determined that 150 could detect the bitter taste of PTC and 65 could not. Assuming this trait ...
1
vote
0answers
226 views

Microtiter Dish Biofilm Formation Assay- Pseudomonas and Crystal Violet

If Pseudomonas is a gram negative bacteria, it does not retain crystal violet but why is it that so many people are using crystal violet staining in theri Microtiter Dish Biofilm Formation Assay?
1
vote
1answer
39 views

Reverse tomography to create 3D scalpel

Isn't it possible to reverse tomography methods to create means to deliver heat or radiation precisely in 3D? This would be "3D scalpel" i.e. device which would be able to eradicate tumor cells ...
0
votes
1answer
26 views

How many systemic reactions in inflammation?

I have this sentence in my notes Inflammation consists of two local reactions and one systemic reactions. which is difficult for me to accept. Two local reactions are vascular and cellular. I ...
2
votes
2answers
80 views

Clarification on Hatch and slack pathway

The following is a minor clarification that I want to make, since it is rarely addressed directly in most of the texts I have gone through. In C₄ pathway, the chloroplasts are dimorphic, that is, ...
1
vote
2answers
56 views

Multicellular organisms as DNA banks

Animal -> bacterial gene transfer seems easier than bacteria -> animal (rotifers are an interesting exception); there are bacteria live in close contact to us but our germ-line cells are protected. ...
0
votes
1answer
41 views

Why do doctors do chemo or transplantation for cancers that don't respond well to these treatments? [closed]

From the UpToDate article on multiple myeloma: In most people, chemotherapy partially controls multiple myeloma; rarely, chemotherapy leads to complete remission. Also: Transplantation, ...
3
votes
2answers
101 views

Why do humans circulate monosaccharides instead of disaccharides as in plants?

Plants transport food mostly in the form of disaccharides like sucrose but humans transport them in the form of a monosaccharide - glucose. What is the reason behind this ?
0
votes
1answer
233 views

What is the benefit of using Gonoline-Euroline in combination? [closed]

I was heard that this combination first Gonoline and other culture another culture on Euroline is good one. What is the benefit of using Gonoline-Euroline in combination?
1
vote
1answer
35 views

What are the best detection medias for cholera?

I heard this fact that you can use some [hypertriade] for vibrio cholera diagnosis which has compontents sucrose (yellow) mannose (yellow) arabinose (do not ferment; stay dark pink) I did not find ...
0
votes
2answers
98 views

What is the right spelling for this agar? [closed]

I could not spell the agar [gonoline-uroline] which I heard yesterday. My spelling is so wrong that I could not find it in Google. What is the right spelling for this agar?
6
votes
3answers
396 views

Does a neuron ever generate an action potential without stimuli?

Most accounts I read involving action potentials and synapses and the like tend to focus mostly on the action potential as a mere automatic reaction to another similar event happening upstream. From ...
0
votes
3answers
936 views

Why do we exhale after we hold our breath?

I tested this out with my friends, and I find that after they hold their breath and can't hold it anymore, they exhale air, instead of inhaling air. Interestingly, they all try to inhale in as much ...
0
votes
1answer
54 views

Shigella's O antigen (PAI synthesised) and passage through host defences

The O antigen is synthesised by Pathology islands (PAI). O antigen may be a factor why Shigella survives the passage through host defences. I am interested in which step of pathogenesis. There are ...
2
votes
1answer
58 views

GULO only for mammals?

I am not a biology student, but just want to know if GULO gene are present only in mammals or all species possess it ? And is GULO gene active in human fetus?
0
votes
0answers
37 views

Can we define biological age? [duplicate]

How can we define ageing from a biological standpoint without making an appeal to chronological age? Related, but less important, are there any metrics we can use to determine someone's biological ...
6
votes
1answer
126 views

Hill-Roberston effects and effective population size

From this article, first page, middle of the second column: Even if harmful alleles do not become fixed, they can still reduce the efficacy of selection on neighbouring loci through a process ...
1
vote
2answers
82 views

Can viruses be used to extract oil from algae?

I read that one hard step in algae oil extraction is to rupture (or fracture) the cell walls to get the contents inside. Some people use chemical methods; some use sonication or mechanical forces. I ...
2
votes
1answer
3k views

Isopropanol precipitation of DNA - duration and magnitude of cold storage

DNA prep protocols often include a final precipitation step with alcohol, often isopropanol, where the DNA must be kept in the alcohol, at a low temperature such as -20C or -70C, often overnight. ...
3
votes
1answer
228 views

Meiosis vs. Mitosis

Meiosis is a type of cell division that reduces the chromosome number from 2n to n to make gametes viable for reproduction in humans. I know that during meiosis, there is independent assortment and ...
2
votes
1answer
118 views

Does recombination increase the additive genetic variance for fitness?

On this article, first column, eighth line of the introduction: By bringing together favourable alleles from different chromosomes, sex and recombination increase the additive genetic variance for ...
1
vote
1answer
37 views

What indices can we use to describe fitness landscapes?

We usually talk of smooth or rugged fitness landscape. Are there any (standard) indices to measure the "structure" of fitness landscapes? For example, one might consider the mean epistatic ...
4
votes
1answer
3k views

Rate of cell division in humans

On average, how many cells divide each day in a human being? How long does a cell wait before dividing itself ? I have tried to look on the internet but surprisingly the answer is difficult to ...
2
votes
2answers
196 views

Primer design and BLAST E value stringency

When searching for misprimings I have been told that an e value that is higher than 0.01 is ok and will produce no significant amounts of mispriming. Yet I searched some and it would seem that the e ...
0
votes
1answer
373 views

Difference between Cary-Blair and Amies transport media for Staphylococcus and Streptococcus?

I normally use Amies medium, but I today heard that Cary-Blair is also possible. When should you use Cary-Blair medium?
2
votes
2answers
2k views

Why there is a very high drop in pressure from arteries to arterioles?

Laplace law explains why the pressure is the same in aorta and arteries (100). I am thinking why there is so big drop in pressure when going from arteries to arterioles (40-60). Why there is a great ...
1
vote
1answer
62 views

Genome Assembly Using Reads

I'm taking an online bioinformatics class and I am stuck on a problem. The resources I have found don't help that much. Here is the problem: "Assemble the error-free reads from a circular genome on ...
0
votes
2answers
170 views

Systemic sensory confusion?

Sometimes when a person gets touched on one part of the body they feel it else where and may think it came from a different part of the body. What causes this? Other examples are similar to why you ...
1
vote
1answer
35 views

Difference between Fulminant and Acute Meningococcemias

Fulminant seems to mead rapid. There is however some articles with both phrases: "fulminant meningococcecemia" (about 5000 Google matches) and "acute meningococcecemia" (about 3000 Google matches). I ...
2
votes
1answer
42 views

What's the best way to measure/calculate the size of a light beam at the sample of a microscope?

I am using a microscope with an LED derived light through the epi-fluorescent port of a microscope. I know that the "field of view" for a given objective is equal to the field number/magnification ...
4
votes
2answers
338 views

How does the brain know where a signal came from? What is the addressing system

I am an electronic engineer so I am thinking about this from an electronics outlook. How does the addressing system work, As I see it, the nervous system is small parallel branches attached to larger ...
0
votes
1answer
21 views

Is Rheumatic fever more Chronic than acute?

It follows from the complication of S.pyogenes' pharyngitis. I am thinking how the inflammatory response behaves: acute or chronic or something between. I think chronic disease is better description ...
0
votes
1answer
126 views

M-type potassium channels by muscarinic receptors

How does the closure of M-type potassium channels by muscarinic receptors result in increased excitation of the target neuron?
0
votes
1answer
205 views

Pathway mediates nitroglycerin-induced relief from angina pectoris [closed]

what kind of Pathway mediates nitroglycerin-induced relief from angina pectoris,please provide some idea...

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