All Questions

11
votes
1answer
1k views

Do fish break a water molecule to absorb oxygen?

How do fish separate oxygen from H20 & consume it? Do they break the water molecule and absorb the oxygen only?
1
vote
1answer
4k views

Which enzyme catalyzes transcription and which translation?

My attempt: Transcription - RNA polymerase Translation - aminoacyl tRNA synthetase I know that the ribosome almost runs translation, but I don't think ribosomes are enzymes, which is why I went ...
5
votes
1answer
206 views

How are DNA polymerase error rates measured?

It is well known that the first DNA polymerase, Taq, is quite error prone. Newer generation commercial enzymes that have either been isolated from different thermophile species or have been improved ...
8
votes
1answer
768 views

Digital Genomic Footprinting for ENCODE

I'm reading over the ENCODE Nature papers, and one of the papers referred to is "Global mapping of protein-DNA interactions in vivo by digital" by Hesselberth et al[1]. Genomic footprinting is a ...
11
votes
2answers
198 views

Why do most breast cancers occur in women?

According to Korde et al. (2010): Male breast cancer accounts for less than 1% of all cancers in men and less than 1% of breast cancers. This raises the question: Why do most breast cancers ...
8
votes
1answer
553 views

How to prevent protein precipitation?

I'm trying to label a protein with fluorescent dye (TMR succinimidyl ester), but having trouble getting the protocol to work. The protein seems to be stable in distilled water at a the recommended ...
6
votes
1answer
238 views

Models of quorum sensing for multi-agent systems

Quorum sensing is a system of stimulus and responses correlated to population density that is used by bacteria to coordinate gene-expression. I am looking for a simple computational/mathematical model ...
2
votes
2answers
205 views

Is consuming sugar with food as beneficial as consuming glucose (~half of the amount of sugar)?

A few years back I heard at biology class that sugar's molecule consists of half the number of elements of a glucose molecule. So not counting the energy needed to transform two sugar molecules in one ...
9
votes
1answer
1k views

Why are some berries poisonous?

In my understanding, the evolutional function of berries is to be eaten and pood out somewhere else, so that the seeds of the plant spread. Is this so? Then why are some berries poisonous?
7
votes
1answer
123 views

Pharmacologically, can tricyclic antidepressants have a side-effect profile similar to neuroleptics?

Torticollis (wryneck, cervical dystonia) is a neurologic movement disorder causing involuntary muscle spasms in the neck. Often, neuroleptics can cause such a side effect. I'm wondering if this ...
3
votes
2answers
71 views

Microbiome Data

How is it possible to access microbiome data like that found here? I'd like to perform analyses on similar type of data, but cannot find OTU data like that at the Human Biome Project. Thanks for any ...
3
votes
2answers
464 views

Is there a physiological difference between love and infatuation?

I find that people generally distinguish between love and infatuation. Is there a physiological difference between the two? Or are they biologically identical, and the difference is circumstantial?
6
votes
3answers
667 views

How exactly are game theoretical evolutionary models described during implementation for computer simulations?

When a biologist or a layman tries to reason the evolutionary explanation for something, they would simply use English with some math thrown in (for a random example, pick any explanation out of "The ...
3
votes
1answer
1k views

Can a person become addicted to tea?

Can one become addicted to tea like coffee addicts or smokers? I heard there are some common substances in tea and coffee, do they cause addiction?
5
votes
1answer
126 views

Phenotypic Variation of cattle - looking for academic sources

Can someone please point me in the direction of a good academic article on the following: What are possible sources of phenotypic variation of different 400 day weights of cattle? Furthermore how ...
3
votes
1answer
174 views

What is the relationship between Homocysteine and Norepinephrine metabolic cycles?

I've been researching neuromodulators and have taken a look at the Norepinephrine/Noradrenaline system. The diagram of biosynthesis of Norepinephrine is presented in the wikipedia article: ...
8
votes
3answers
337 views

Does human digestive system benefit from eating same kind of food consistently?

Here's the reason why I'm asking: I've heard that it takes some time for pets(cats/dogs) to adjust to a different dry feed, where the new feed has to be mixed with the old one, slowly replacing the ...
2
votes
3answers
82 views

Is DNA mutation locally energetically stabilizing the DNA molecule

I am no biologist, but as a physicist, a spontaneous mutation (seen as a chemical transformation) should lower the energy of the system, at least locally. So I wonder if any research has been done ...
8
votes
3answers
232 views

Is there any documented evidence for suicide among vertebrates other than humans?

Is there any documented evidence for suicide among vertebrates other than humans? Lemmings not accepted !
3
votes
2answers
144 views

What is the species of these mushrooms?

The mushrooms are gilled with a light-brown cap. The stem is widened to the base. What species is it? Is it considered edible? They are found in mixed forest in Moscow, Russia. They grow in the ...
2
votes
1answer
190 views

How to learn DNA Origami

Can you tell me is there any good softwares and tutorials which can be used to learn DNA Origami. I am new to this and want to learn from basics. Advance thanks for your help edited: INSILICO
4
votes
1answer
57 views

Does retinal detachment happen more frequently at night?

My understanding and experience is that during the night photoreceptors are less tightly coupled to the retinal pigment epithelium. Does this make it more likely for a retinal detachment to happen at ...
3
votes
2answers
314 views

Why is the frog genome so much larger than a fish's?

As we have heard in the summaries of the human ENCODE project, 80 per cent of junk DNA appears to have an essential function. Many fish have a genome with only one tenth the size of a usual vertebrate ...
7
votes
2answers
460 views

What distinguishes “coding” and “noncoding” DNA from each other?

I've been reading a bit about "junk DNA" and how much of our genome consists of this "non coding DNA" in comparison to "coding DNA". I'm just an interested layperson but I thought all combinations of ...
0
votes
1answer
435 views

Is breathing in deodorant fumes dangerous for my brain?

I noticed that I sometimes get dizzy when I accidentaly breathe in too much Axe. Also, I find the smell of alchohol rich deodorants quite unpleasant. But, I was wondering, is it actually dangerous? ...
5
votes
1answer
120 views

Mutation-immunity in Luria-Delbruck experiment

If experiments like those of Luria and Delbruck on E. coli and T1 phage are the main source of our confidence in the mutation-immunity model, is it then highly unlikely that there are other types of ...
14
votes
2answers
2k views

Is there an advantage to linear chromosomes?

The DNA copying enzymes have a hard time working to the end of a chromosome. For circular chromosomes this is not a problem, since there is not a sharp 'end'. However, for a linear chromosome, without ...
4
votes
1answer
168 views

Is cell senescence in culture comparable to that in vivo?

A cell is 'senescent' when is has permanently left the cell-cycle. This can be caused by stresses, or by reaching the 'Hayflick limit' (the cell has reached its replicative lifespan, as defined by its ...
4
votes
1answer
140 views

How does “inheritance of methylation” of DNA and/or histones work?

What are the current models/ideas describing the mechanisms explaining inheritance of methylation on DNA resp. histone level? Is there evidance of this "setup" information being really ...
3
votes
0answers
94 views

Terminology question: the scope of an allele in an organism

Let us consider a gene FOO with novel type foo. If I were discussing an organism that has inherited foo in every cell during classical zygote formation, then I would ordinarily just say that the ...
10
votes
4answers
775 views

Why is it sometimes difficult to resuspend E. coli in P1?

It's a curiosity question. When I'm doing minipreps after pelleting the bacteria sometimes it's very easy to resuspend them in P1 (Qiagen kit), but sometimes they form a rubbery clump that is very ...
5
votes
1answer
64 views

on/off behavior of neural networks

What causes a group of disembodied neurons in a dish to fire after a silence? If there are no neurons providing a stimulus for more firing (as in a dish of disembodied rat neurons), then why don't ...
-1
votes
1answer
4k views

Ramifications and possibility of a diet consuming exclusively of human semen

Semen is a thick, nutritious liquid, rich in vitamins (such as C, B12), amino acids, lipids, monosaccharides (fructose), et cetera. Can semen's ability to fulfill the needs of human organism provide ...
5
votes
1answer
340 views

What are good practices with reusing desalting columns

At least according to a few sources Prozyme and Protocols-Online, it is possible to reuse desalting columns and since I'm cheap I would like to also. Key things seem to be washing with several column ...
0
votes
1answer
215 views

From which ancestor species did humans inherit orgasm?

From what ancestors did humans inherit orgasm? Do fish experience orgasm? Are the male and female orgasm the homologues that can be traced to the time when there was no difference in sex between ...
7
votes
0answers
441 views

Rosetta ab initio prediction and protein-protein interaction fitness help [closed]

I have designed several proteins which I predict have interactions with another protein using the sequence based Conjoint Triad Method. I would like to know which ones structurally are predicted to ...
3
votes
0answers
47 views

Literature about putative epigenetic state changes in mammal sequences after cloning steps in Escherichia coli

I would like you to point me out some literature about putative epigenetic state changes in mouse/mammal sequences after cloning steps in Escherichia coli. This are the last search details I used in ...
9
votes
5answers
3k views

Difference between genetic engineering and synthetic biology

I've recently seen the term synthetic biology being used to describe research involving genetic modification of organisms. What is the difference between synthetic biology and genetic engineering? Is ...
7
votes
2answers
344 views

Why do stranded marine mammals die so quickly?

Mammals have lungs, so do marine mammals. Nevertheless some marine mammals seem to die rather quickly when they strand on a beach. As they have lungs and can breath while on land, why do they die so ...
6
votes
2answers
166 views

Why are some viruses not communicable person-to-person?

Below are two quotes from the CDC about Hantavirus: "Researchers believe that people may be able to get the virus if they touch something that has been contaminated with rodent urine, ...
3
votes
1answer
134 views

Which part of a female mantises's DNA causes her to be a few times larger than a male mantis?

Which part of a female mantises's DNA causes her to be a few times larger than a male mantis? Do other species have that part of DNA?
3
votes
3answers
380 views

Looking for Kelly Chibale's paper on Malaria cure

From National Geographic, there has been a lot of hype on Kelly Chibale's work from University of Cape Town on the aminopyridine MMV390048. Unfortunately, this was from an announcement from an ...
4
votes
1answer
1k views

What is a focal copy number variation?

Often, genetics studies, especially genome wide ones, talk about "focal copy number variations" in genes or regions of the chromosome. I know what a copy number variation is. What does "focal" mean, ...
5
votes
1answer
280 views

Where can I find the tissue-specific protein expression levels for hTERT (telomerase subunit)?

I find a number of contradictory sources regarding the tissues in which hTERT - the protein - is expressed. Does anybody know some resource that authoritatively (as authoritative or widely-accepted as ...
3
votes
2answers
90 views

What are the different, high-level programs along which a eukaryotic animal cell can follow?

What are the different, high-level, disjunct (mutually exclusive at one particular point in time) programs or pathways along which a eukaryotic animal cell can follow? Examples of programs would ...
4
votes
1answer
139 views

Non-monotonic knock-out effects in prokaryotes

Typically, when performing gene-knockout, the experimenters select one gene to remove/replace-with-junk and then see if the prokaryote can still undergo fission. If it continues to reproduce then the ...
7
votes
1answer
136 views

Making penicillin using animals - specifically, a goat

In the scifi novel Lucifer's Hammer, one of the characters (a biologist, if I remember correctly) finds himself in a post-apocalyptic world and tries to make penicillin to save his own life. To do ...
3
votes
2answers
68 views

Is vision a vestigial sense for deep ocean species?

Sunlight doesn't penetrate beyond a couple of hundred feet from the surface of the ocean. Species that exist at greater depth probably live in a state of perpetual night; yet from a quick google image ...
3
votes
3answers
6k views

Evolutionarily speaking, why do humans have 46 chromosomes

In humans, each cell normally contains 23 pairs of chromosomes, for a total of 46. Monkeys, chimpanzees, and Apes have 24 pairs (twenty-four pairs), for a total of 48. What caused humans to have 46? ...
3
votes
0answers
104 views

Cheapest Way to Measure Germ Density

I would like to measure the surface density of Staphylococcus bacteria and Rhinoviruses (only those two, to be specific) within my home. What's the cheapest way? The textbook procedure is to: rub ...

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