6
votes
2answers
9k views

How do archaea relate to eukaryotes and bacteria?

I've read that they all share some genes, internal structure, and behaviour with each other, but with different degrees of overlap depending of what the function is. E.g., archaea have some eukaryotic ...
4
votes
1answer
93 views

Online toolkit that provides functional similarity scores (in the form of a matrix) between two functional gene sets in the context of gene ontology

Where can I find an online toolkit that provides functional similarity scores (in the form of a matrix) between two functional gene sets in the context of gene ontology? I have tried the following: ...
6
votes
1answer
142 views

Alternatives to fittest-win and Moran processes as simple mathematical models of selection

When modeling selective sweeps as a micro-building block in models of macroevolution (not to be confused with misuses of this in creationist arguments), I use the fittest-win model of selection as a ...
6
votes
1answer
227 views

What is the relative power of GWAS studies in different species?

I would like to know of any publication studying the relative power of GWAS studies in different species. For example, I've seen reports that say genotyping and GWAS in dog breeds is much more ...
3
votes
1answer
183 views

What is the DNA/protein charge ratio?

To study DNA-protein interaction, I want to do a DNA retardation test by mixing the protein with DNA and afterwarts loading it on an agarose gel to see if the DNA migrates slower. I've found some ...
3
votes
1answer
4k views

What does the term 'bioavailability' mean?

From what I've read, Bioavailability is the degree to which food nutrients are available for absorption and utilization in the body. How would you explain this with an example?
6
votes
1answer
302 views

Can I estimate leaf temperature from air temperature? What other information would be required?

Physiological measurements such as respiration rate and assimilation rate depend on temperature. Most papers report tissue temperature (e.g. leaf temperature for leaf measurements), although some ...
1
vote
1answer
33 views

Where can I find a transcriptome of a normal uveal melanocyte?

I am looking for a database where I could find a transcriptome (say obtained with a microarray analysis) of one (or ideally many) normal uveal melanocytes ?
1
vote
1answer
71 views

TFBS predictions for yeast and pombe?

Are there any resources out there for TFBS (transcription factor binding site) predictions for the yeast (S. cerevisiae) and S. pombe genomes? Even if these are only de novo predictions, I would like ...
1
vote
2answers
291 views

How are proteins formed?

Somewhere, I have read that we need to consume proteins to make amino acids to make new proteins. What does it suggest? How do we make proteins from proteins?
6
votes
1answer
123 views

Designing genes with DNAWorks: Maximum nonzero score?

I'm designing a gene in DNAWorks, and I'm unable to find a set of conditions that gives an "overall score" of zero (which is what I normally insist on). People that have used DNAWorks: what's the ...
10
votes
1answer
263 views

How old does a baby have to be before it can retain memories?

For most people (my earliest memories are of perhaps when I was 2 or so) their earliest memories would be when they were over a year old. How old does the average baby have to be before it can ...
7
votes
2answers
276 views

Why do people have darker skin in sunnier climates?

I don't understand why darker skin is advantageous in hotter climates. Wouldn't it absorb more of the heat? I have heard that it reduces the incidence of cancer, but I would think absorbing more ...
6
votes
1answer
143 views

Are there any DNA base sequences that are fully conserved between the genomes of all humans?

That is, they don't differ throughout the entire population. I understand of course that we can't DNA sequence every human, so by "fully" I mean there's an incredibly small probability of there being ...
7
votes
2answers
5k views

What are the consequences of voluntary total celibacy?

Psychologically this might be a tough question, but in means of biology, what are the effects of total celibacy on the gonads and the nervous system concerning both man and woman in short and long ...
2
votes
1answer
76 views

Are there any organisms with larva more advanced than adult form?

Usually adult organisms are more sophisticated than corresponding larva, i. e. frogs, mosquitoes, fish. Are there species where the opposite is true?
11
votes
4answers
604 views

Pipetting damage on cells

I'm curious how much damage is potentially inflicted by shear stress by pipetting. I know that with syringes for stem cell injection cause a lot of damage. However, to what extend does this happen ...
3
votes
1answer
1k views

What are the units of Q10 (temperature sensitivity)?

Q10 is the increase in a rate (e.g. activity of an enzyme) observed with a 10 degree temperature increase. According to Wikipedia: It is apparent that the units of R (e.g. mol/g/s) cancel out, ...
1
vote
0answers
57 views

bam viewer that works on authenticated ftp urls with username/password combination? [closed]

Are there any BAM file viewers that will work on authenticated ftp urls with username/password combination? For example, something like this: ...
4
votes
2answers
81 views

How do proteins and genes participate in learning?

I am a computer scientist that studies biology and bioinformatics. In the last weeks, I have been trying to study new research directions, and I would like to deepen my knowledge on the role and ...
8
votes
1answer
320 views

Is sexual reproduction outside the same biological family possible? Has it ever occured successfully?

Are there any examples of two species taxonomically classified in different biological families that have successfully hybridized and produced viable offspring? If not, is there an example of where ...
6
votes
2answers
536 views

Finding the number of chromosomes of an organism

For a school project I need to find the number of chromosomes of an organism (specifically the adelie penguin, Pygoscelis adeliae). After several internet searches and a look through the encyclopedia ...
1
vote
1answer
921 views

Is there a free alternative to Gelcompar for comparing banding patterns across multiple gels?

In order to run my microbial community samples from my experiments through DGGE, I was required to use multiple gels. Thus it is necessary to compare banding patterns across more than one gel. ...
5
votes
1answer
111 views

Significance of basal lamina for outer layers of epithelium

In stratified (not pseudostratified) epithelia such as the epidermis, what purpose does the basal lamina serve for the outer layer cells which do not even stand in contact with it? Also, how do these ...
-3
votes
1answer
665 views

How does protein help to cure wound? [closed]

I understand that the protein helps to repair body tissues. If I increase the intake of protein, would it help to cure the wound more quickly? I would like to know how does the protein reaches the ...
5
votes
1answer
140 views

Homologies to insect wings

All winged vertebrates have wings which are homologous to each other and to the forelimbs of the non-winged vertebrates. But what about insect wings? Are all insect wings homologous, and are there any ...
7
votes
5answers
331 views

Introductory literature for synthetic / systems biology?

I'm a computer engineer (MsC Computer Engineering) who's looking to switch into the field of synthetic / systems biology. I've got a comprehensive layman's understanding of evolution, genetics, ...
0
votes
1answer
267 views

Why does a drop of water penetrate deep sleep? [closed]

Sleeping under the stars, a breeze carrying a few drops of water came by. The sense of water drops on my arms woke me up. I'm curious Why does the sense of a drop of water on one's body penetrate ...
12
votes
4answers
482 views

Why did high A+T content create problems for the Plasmodium falciparum genome project?

The main paper for the Plasmodium palciparum genome project (Gardner et al., 2002) repeatedly mentioned that the unusually high A+T content (~80%) of the genome caused problems. For example they imply ...
2
votes
1answer
95 views

What are Haplogroups?

What exactly does the term Haplogroup or Haplotype means? How is it claimed that people belonging to the same haplogroups have common ancestors?
5
votes
3answers
2k views

How does Artificial Selection work?

As far as I know for evolution to work mutations are necessary. Mutations are the raw material on which natural selection works. But mutations are always completely random and human beings have no ...
3
votes
1answer
304 views

What are samples of “Outlaw Genes”

I read this in a paper Keller and Ross describe their greenbeard gene as an ‘outlaw’. Admittedly, the comment is only made in passing, but are they correct? In this context an outlaw is ...
7
votes
1answer
334 views

How fast do different organs turn over cells?

It is said that the human body turns over all cells or molecules in 7 year cycles. This is not quite correct, because there are different organs changing at different speeds. My interest is what is ...
3
votes
2answers
296 views

Two subunits connected by only one disulfide bridge: quaternary structure?

I've always simply assumed quaternary structure to be characterized by non-covalent interactions such as hydrogen bonding, van der Waals interactions and whatnot. However, if two distinct polypeptides ...
7
votes
2answers
105 views

Does the word “polymorphism” refer to the gene, the phenotype, or both?

In genetics, does the word "polymorphism" properly refer to genes, to phenotypes, or both? For example, if there are two alleles that lead to differences in the structure of the D2 neuroreceptor, ...
4
votes
1answer
145 views

Regarding TIMP and MMP enzymes

Are there substances that can promote TIMP enzyme production, or MMP enzyme production or supression in tendons? Are there medical tests that measure quantities of MMP and TIMP enzymes in tendons?
0
votes
2answers
644 views

What part of food gives the blood red color?

Roughly, what I know is, when we eat food it goes into our: Stomach > Small Intestine > Large Intestine > Rectum. So, it just moves through a digestive pipe. What I don't understand is, what part of ...
8
votes
1answer
406 views

Why are we using upper teeth and lower lip on labiodental sounds?

I came to wonder this when studying language (as well as other same theme question posted just few ago). For example the word "fantastic" we use upper teeth and lower lip to produce F sound, instead ...
5
votes
1answer
690 views

How and why did mouth and nasal cavity evolve separate?

My initial objection is that nose filters air, mouth is for eating but is used for breathing also, plus they both are used to create sounds. What is the cause and reason in this case, why do we need ...
2
votes
0answers
152 views

Too few transcripts from transcriptome assembler Oases

I am trying to run Oases for transcriptome assembly. The result is far from expected, so I would like to ask whether I am running it in a right way? Thanks. Here is my running command: ...
3
votes
1answer
5k views

What is the functional difference between hemoglobin and ferritin?

I read that both hemoglobin and ferritin are for storing iron in the body. So, what is the difference between them in terms of storing/binding iron?
3
votes
1answer
13k views

Why are (some) cats attracted by bleach?

(Sorry if this question is only partly biological) I have noticed that several cats (including the one that keeps sleeping in my house), are fond of the odor of bleach (eau de Javel) and chlorine. ...
8
votes
1answer
135 views

Is there a comprehensive database of fossils (with images) online?

Not sure if this is the best stackexchange to ask... I have not been able to find a decent database of fossils on the web, does one exist? Here are some of the links I have found through Wikipedia ...
3
votes
1answer
95 views

Color of the Fur coat of Polar bears

Recently I was playing a quiz and a question was asked about the color of the fur coat of a polar bear. To my surprise the answer was black. I thought it was yellowish white or creamy. Why so ?
28
votes
2answers
572 views

Why don't teeth glow?

Hydroxyapatite is the main component of tooth enamel. It contains phosphorus in the form of phosphates, pyrophosphates etc. that are found to exhibit the the property of phosphorescence. But why don't ...
6
votes
1answer
86 views

Can NSAIDs impact negatively the healing of tendons?

There are a number of articles regarding NSAIDs having a negative effect on healing conditions like tendonosis and tendinitis. From what I understand the channel through which they reduce inflammation ...
8
votes
1answer
99 views

What would be the best dredging/trawling tools to collect macrofaunal priapulids?

Title says it all. I've been searching for the best way of collecting macrofaunal priapulids and would like advice on sampling methods and particularly sampling tools. Since large priapulids are ...
7
votes
1answer
534 views

ChIP-seq vs ChIP-exo

I'm currently investigating ChIP-seq vs. ChIP-exo for finding binding sites. As far as I can tell, ChIP-exo seems to be better in every way than ChIP-seq... but then again, I'm not strong in this ...
3
votes
2answers
123 views

How distantly related are eusocial insects? Aren't members of a species much more related than 1/4, 1/2, or 3/4? [duplicate]

Possible Duplicate: How many genes do we share with our mother? I went to a lecture that talked about the behavior of social insects in terms of their relatedness of genes. For instance, ...
12
votes
4answers
214 views

Are there any examples of proteins with no or minimal sequence identity, but highly similar structure?

What are they, and do they share a common ancestor? How far back in evolutionary time must we go to find them? If none are known, what computational tools might be used to search for such examples?

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