All Questions

1
vote
0answers
62 views

Is pure (100% H20, (near to no) solutes) water toxic to living organisms? [duplicate]

Possible Duplicate: Death because of distilled water consumption I know about the effects and myths about drinking distilled and/or deionized water. I'm not asking about such substances. I ...
-4
votes
1answer
307 views

Why hasn't mother nature made us aware of our lizard brain? [closed]

In many personal improvement books I've read, people make a distinction between 2 parts of our brain: the logical brain, dealing with logic, judgement, thinking; what makes Humans different than ...
6
votes
1answer
213 views

What's the state of the art in designing and creating your own life forms?

What's the state of the art for solving the following problem. You imagine a set of features that you want a life-form to have. Just to take an arbitrary example, say you want your life-form to have ...
7
votes
1answer
154 views

Is the function of adjacent genes correlated?

Do genes that occupy a similar locus on the genome have correlated function, specifically in human beings? It is my understanding that adjacent genes are inherited together, and so location plays a ...
1
vote
2answers
522 views

Shouldn't evolution have taken care of baldness already?

It is my understanding that the hair on the head is there to protect us from sunburn. I've never seen a bald animal, so isn't evolution in charge of addressing these type of things? How is it that ...
12
votes
2answers
4k views

Do men have significant hormonal cycles?

I know there's a similar question here. But that discussion dissolved into lunar cycle and a correlation with it. I want to find more towards the original question of is there a periodic hormone ...
3
votes
2answers
193 views

Do both TSG and Proto-oncogenes have to suffer mutations to cause cancer?

I'm having a conceptual nightmare trying to understand when a group of cells may become cancerous and the more resources I consult the more confused I seem to get. In order for a cell to become ...
7
votes
1answer
71 views

How does one measure the length of telomeres?

My questions are: What techniques are available for doing so? Are they destructive ? What is their accuracy ?
5
votes
3answers
58 views

Do you know of any disease where HLA / MHC association discovery has led to better treatment or management?

If we discover an association between a disease and a particular HLA type (MHC class I or class II molecule) then it may provide us with some insight into the disease in a very basic way. However, ...
5
votes
2answers
182 views

How high is the energy yield of photovoltaics compared to photosynthesis?

I'm not an expert in plant physiology. I was wondering if, per square centimeter, leaves are converting more or less energy than photovoltaic systems. Can this be estimated? How?
6
votes
1answer
791 views

Examples of intracellular parasites of medical or economic importance?

What are examples of intracellular parasites of medical or economic importance? I have read that Xanthomonas oryzae is an intracellular parasite in rice that produces proteins able to cause changes in ...
13
votes
3answers
2k views

When has an organism evolved enough to be called a new species?

Imagine that we take a population of horses, split them in half and place them in completely different environments. The two species will evolve separate from each other and because the environment is ...
0
votes
1answer
459 views

Are there examples of the green beard effect in humans?

Green-beard effects are genes that: Produce an effect that can be detected Produce preference to others with the same effect Are there any examples of this in humans?
9
votes
3answers
1k views

Why does the butterfly have a cocoon stage in its life cycle?

Why does the butterfly have a cocoon stage in its life cycle? It could have simply grown up within the egg/cocoon, and emerged as a butterfly. Instead it is first an egg, then a worm, then a ...
2
votes
2answers
158 views

Can the body of any organism on Earth live without impairment both in vacuum, and within Earth's atmosphere?

I know from reading that a human in vacuum needs a space-suit to survive. Is the body of any organism on Earth capable of living equally in vacuum, and on/below Earth's surface within the ...
3
votes
2answers
361 views

Why Didn't Evolution Cause the Human Body to become Streamlined?

If streamlining makes movement/locomotion quicker and easier, why didn't the apes evolve into life-forms that had streamlined bodies (much like fish)?
9
votes
3answers
9k views

Hoechst or DAPI for nuclear staining?

When is it best to use Hoechst vs. DAPI for nuclear staining? They seem to be very similar on paper. Are there situations where one is clearly preferable?
3
votes
1answer
3k views

Why is beta-mercaptoethanol often added to cell culture media

Many protocols suggest that beta-mercaptoethanol is necessary for growing cells. It is a reducing agent but what does it mechanistically do for your cells. When would one not add it.
5
votes
1answer
136 views

Does every gland type have stem cells for regeneration?

Is there any gland in which there are no stem cells? I know that: sebaceous gland is maintained by unipotent stem cells thyroid gland - some stem cells, apparently unipotent Glands about which ...
3
votes
2answers
3k views

How do you calculate or predict the charge of a protein at pH 7?

How do you calculate or predict the charge of a protein at pH 7 given a fasta sequence? Any papers or online servers to do this is well appreciated.
4
votes
2answers
155 views

What is the purpose of the adrenal medulla?

The adrenal medulla is less of a 'real' endocrine organ like the others in the endocrine system and much more an extension of the sympathetic nervous system. In fact, its chromaffin cells are modified ...
2
votes
1answer
56 views

What is an efficient way to spike 10-50 cells to a culture

I'm trying to add on the order of 10-50 mammalian cells to a mixture of other cells (order of 1e6 cells). What is the best way to do this? (edit) I guess this wasn't clear. I would really like to ...
10
votes
4answers
7k views

Do we get 1/4 of our genes from each grandparent?

I know that we get half of our genes from each parent, but does it necessarily mean we get 1/4 of our genes from each grandparent? Or is it possible that we might get say 30% from one grandparent, 20% ...
3
votes
1answer
744 views

What happens when cells in your body run out of telomeres?

In my biology book I read about an experiment where the genes encoding telomerase were 'knocked out', but they could still live a normal life and no adverse effects were noticed until the 6th ...
5
votes
1answer
121 views

Is extreme cladism a mainstream position in the species debate?

In the philosophy of biology it has been claimed many times that a popular position regarding the question of what species are, among biologists, is cladism. For my current purposes, the defining ...
6
votes
1answer
88 views

DNA methylation and genome size

Is there any relationship between DNA methylation as a level of stability to epigenetic states and genome size? For example, it is claimed that DNA methylation is not required for epigenetic stability ...
3
votes
1answer
474 views

Is collagen supplementation useless?

When collagen is digested is it broken up into usable components that the body can use to produce its own collagen? What evidence is there that supplementing with collagen type I & II etc.. can ...
4
votes
1answer
66 views

Features in individuals causing high population variation

As I understand it, a population with high variation is something sought after, since it makes the population better equipped to face a dynamic environment. Then, I guess features in an individual ...
7
votes
1answer
105 views

Do any plants exhibit hormonal changes similar to puberty?

Just what the title states. Are there any plants/trees that exhibit a growth spurt at a definite interval after the shoot appears?
7
votes
2answers
130 views

Genetic Models for Natural Selection?

My question is simple: Given that evolution is described by random genetic mutations allowing certain members of a species to gain a reproductive advantage over others that coexist in the particular ...
11
votes
1answer
276 views

Do single crossovers occur in circular polynucleotides?

Single crossovers in circular pieces of DNA do not seem to be a big topic, because if they happened, they would lead to a kind of combined chromosome with two inner strands and one large outer strand. ...
5
votes
1answer
2k views

What are tendons made of specifically

From what I read on wikipedia they are made of collagen. Collagen is just a protein. Right? How is this collagen structured (I imagine like fibers). Aren't there cells in this fibers as well? From ...
3
votes
0answers
243 views

What is the timing of information assimilation within a human brain? [closed]

A little background: I'm an avid dreamer and have great dream recall, sometimes up to 5-7 per night. In my experience, I can sometimes trace some elements of the dream to an event that occured ...
3
votes
1answer
428 views

Could inhibition of progerin formation slow the rate at which a body ages?

According to wikipedia, progerin is activated in senescent cells. The protein itself is known to be the cause of a rare affliction 'progeria' - a disease marked by accelerated aging of the body. This ...
9
votes
1answer
83 views

Relative Property of Alleles

If there are three different alleles to a gene, is it possible that the first is dominant to the second, but recessive to the third?
3
votes
1answer
554 views

Open protocol for Ligase Independent Cloning

Ligase Independent Cloning is a protocol that allow an insert to be integrated into a vector without ligation. It uses T4 DNA polymerase with only ATP to first chew back from blunt ends to create ...
8
votes
2answers
193 views

Is there a consensus on whether or not race exists on a biological level?

The most recent survey I could find was from 1985 which said that 16% of biologist disagreed that "[t]here are biological races in the species Homo sapiens." I was wondering if there's been a change ...
11
votes
1answer
278 views

Deletion errors with Phusion Polymerase?

I was wondering if anyone has ever seen large deletions (~40-50 bp) occur when using phusion polymerase to clone a gene. I have recently tried using Circular Polymerase Extension cloning to clone a ...
6
votes
2answers
9k views

How do archaea relate to eukaryotes and bacteria?

I've read that they all share some genes, internal structure, and behaviour with each other, but with different degrees of overlap depending of what the function is. E.g., archaea have some eukaryotic ...
4
votes
1answer
95 views

Online toolkit that provides functional similarity scores (in the form of a matrix) between two functional gene sets in the context of gene ontology

Where can I find an online toolkit that provides functional similarity scores (in the form of a matrix) between two functional gene sets in the context of gene ontology? I have tried the following: ...
6
votes
1answer
144 views

Alternatives to fittest-win and Moran processes as simple mathematical models of selection

When modeling selective sweeps as a micro-building block in models of macroevolution (not to be confused with misuses of this in creationist arguments), I use the fittest-win model of selection as a ...
6
votes
1answer
236 views

What is the relative power of GWAS studies in different species?

I would like to know of any publication studying the relative power of GWAS studies in different species. For example, I've seen reports that say genotyping and GWAS in dog breeds is much more ...
3
votes
1answer
189 views

What is the DNA/protein charge ratio?

To study DNA-protein interaction, I want to do a DNA retardation test by mixing the protein with DNA and afterwarts loading it on an agarose gel to see if the DNA migrates slower. I've found some ...
3
votes
1answer
4k views

What does the term 'bioavailability' mean?

From what I've read, Bioavailability is the degree to which food nutrients are available for absorption and utilization in the body. How would you explain this with an example?
6
votes
1answer
311 views

Can I estimate leaf temperature from air temperature? What other information would be required?

Physiological measurements such as respiration rate and assimilation rate depend on temperature. Most papers report tissue temperature (e.g. leaf temperature for leaf measurements), although some ...
1
vote
1answer
34 views

Where can I find a transcriptome of a normal uveal melanocyte?

I am looking for a database where I could find a transcriptome (say obtained with a microarray analysis) of one (or ideally many) normal uveal melanocytes ?
1
vote
1answer
73 views

TFBS predictions for yeast and pombe?

Are there any resources out there for TFBS (transcription factor binding site) predictions for the yeast (S. cerevisiae) and S. pombe genomes? Even if these are only de novo predictions, I would like ...
1
vote
2answers
291 views

How are proteins formed?

Somewhere, I have read that we need to consume proteins to make amino acids to make new proteins. What does it suggest? How do we make proteins from proteins?
6
votes
1answer
125 views

Designing genes with DNAWorks: Maximum nonzero score?

I'm designing a gene in DNAWorks, and I'm unable to find a set of conditions that gives an "overall score" of zero (which is what I normally insist on). People that have used DNAWorks: what's the ...
10
votes
1answer
268 views

How old does a baby have to be before it can retain memories?

For most people (my earliest memories are of perhaps when I was 2 or so) their earliest memories would be when they were over a year old. How old does the average baby have to be before it can ...

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