4
votes
0answers
159 views

Long-term effects of antihistamines on mind and CNS [closed]

Can maybe someone share knowledge or guesses on the following questions: Does the prolonged use of antihistamines cause long-term effects on mind or CNS? Are there any known evidences of their ...
1
vote
1answer
153 views

Does physical exercise following lack of sleep increase the risk of sudden cardiac death (SCD)?

Is there any scientific evidence supporting the hypothesis that physical exercise following lack of sleep increases the risk of sudden cardiac death (SCD)? The only relevant research I could find is: ...
1
vote
2answers
52 views

Why are nausea and dizziness such common side effects from medication?

Why are nausea and dizziness such common side effects from medication? If you go through your medicine cabinet and look at side effects, those might just be on every single bottle. Is there some ...
8
votes
2answers
214 views

How was the resemblance between apes and humans explained in pre-Darwinian biology?

Humans and apes have somewhat obvious similarities, these must have been apparent to natural philosophers before the possibility of a common ancestry was first proposed in the mid-1800's. These ...
4
votes
1answer
1k views

How long does it take for a cricket to die at subzero temperatures?

I am on a number of reptile groups and I often hear freezing recommended as a humane way to get rid of surplus feeder insects. However, they can also revive if you don't leave them in there long ...
2
votes
1answer
1k views

What percent of the population has some form of synesthesia?

Data I am trying to get my hands on: What types of synesthesia (e.g. Grapheme-color synesthesia, Chromesthesia, etc.) are most common across the population? What percent of population has that ...
0
votes
1answer
47 views

PCR cycle problem [closed]

IF I began a PCR cycle with 5 copies of a particular DNA section, and copied the section by PCR, for 6 cycles, how many copies of the DNA (include the originals) would I have by the end of these ...
2
votes
1answer
99 views

Neuron Growth and Regeneration

Are nerves and/or neurons able to grow and repair after damage, but not regenerate? Is this specific to humans? I have heard of people being paralyzed, but after much therapy are able to use their ...
8
votes
1answer
2k views

How does the cornea breathe during sleep?

The cornea is not supplied with blood vessels and so exchanges gases directly with the atmosphere. So how does it breathe during sleep when our eyes are closed?
7
votes
2answers
9k views

Why should plants transform glucose into sucrose before transporting it to other parts?

I've learned that plants transform glucose into sucrose before sending it into phloem. But the process seems to be complex and energy comsuming. Why should plants do it? Is it really necessary?
3
votes
1answer
52 views

Prevent biofilm formation on moist surfaces

I have an indoor fountain with lots of water. What are the most common microorganisms in this kind of moist environment, and what are the standard way to prevent biofilm formation by them? I thought ...
3
votes
2answers
793 views

Why does the 'Positive-inside Rule' exist?

Gunnar von Heijne's Positive-inside Rule seems to have been around for a couple of decades and underpins a lot of what we know about transmembrane topology. It is used to predict the topology of a ...
4
votes
1answer
63 views

What's up with all the vague protocols? [closed]

I have lost count of how many protocols I've seen, including those supposed to be professionally written (such as manuals that come with kits from well known brands, or methods sections of papers in ...
1
vote
1answer
38 views

Ebola immunosupression and infection

I was wondering... If Ebola attacks immune cells and causes immunosupression, then shouldn't we see death in Ebola patients due to secondary infection?
8
votes
1answer
2k views

Can a human acquire a memory of an animal? [closed]

I would like to know if it's possible for a human to acquire an animal memory. I mean, animals store their memories in their brain, right? And so do we, humans, store our memory. So, is it possible ...
2
votes
3answers
171 views

Increasing/decreasing signal intensity in Western blotting

So I was in class and my professor was explaining western blotting. It seems as though there's more than one way to increase or decrease the signal intensity. He presented us the challenge to discover ...
5
votes
1answer
250 views

Effect of closed eyes on balance?

Suppose you want to stand on one leg. Doing it eyes open is not that difficult, but doing it eyes closed seems to be difficult. Why?
0
votes
1answer
92 views

What is phenotyping of blood during transfusion process?

Thallaesemic patients are advised to have only "phenotypically matched blood".I mean the transfusion problems arise mainly due to "grouping problems" like mismatch b/w ABO & Rh+/- so what do this ...
2
votes
0answers
39 views

What is the best way to perform ultra-deep targeted sequencing of few samples?

I performed recent whole genome/exome sequencing in tumor samples and now I would like to take a few of these variants (say maximum 50 amplicons) to: 1) Validate them in the original samples 2) ...
4
votes
1answer
83 views

Does a bird know it's different? [closed]

I live in Northern Virginia, USA. As I am sitting here there is a large flock of small (blackish) birds in a tree. They are quite prevalent here. For the sake of brevity I will call these birds ...
1
vote
1answer
278 views

Can a rotten egg actually hatches to a real life?

First of all, I'm no expert in biology. I failed a lot in high school. Please bear with it if it's a stupid question. For the past few days, I got a rotten smell as if an animal died in my kitchen. I ...
8
votes
1answer
1k views

Do the right-handed people tend to use the right side teeth of their jaw to chew food more often than the left-handed people?

And vice versa, do the left-handed people tend to use the left side teeth of their jaw to chew food more often than the right-handed people?Or the frequency of food chewing distribute fairly to both ...
0
votes
1answer
80 views

Which three functional groups are found in the general structure of amino acids? [closed]

Yes, I know, not two, but THREE. EDIT: Yes, sorry but I did quite a bit of research, searching my notes and textbook for the answer, but all I could find was TWO functional groups as a opposed to the ...
7
votes
1answer
175 views

Can rapid eye blinking induce epileptic seizures?

Photosensitive epilepsies are characterized by visually-induced seizures. Flashing-light stimuli are known to induce seizures in some (but not all) patients. My question is whether people with this ...
4
votes
1answer
392 views

Is sexual selection evolutionarily advantageous?

Our biology teacher says that peacocks will soon become extinct because of bigger and bigger (and heavier and heavier) tails. Why natural selection did not eliminate sexual selection?
1
vote
0answers
16 views

how to get truseq's gel size selection when preparing libraries for exome enrichment?

i would normally use a 6 minute fragmentation as quoted by agilent but this gives post exome enrichment libraries of around 300bp or slightly over. Truseq want libraries to be 100bp larger. i am ...
1
vote
1answer
118 views

PCR directly on DNA binds to Ampure XP

During the library preparation it's possible to conserved Ampure beads during the different enzymatic reaction (it's the with beads strategy for improving yield, Fisher et al. Genome Biology 2011). ...
1
vote
1answer
18 views

how to re-sequence a few Mb of genomic sequences?

If I want to re-sequence a known part of the chromosome (we know the reference genome sequence) of ~1Mb to find the possible mutations (SNP or INDEL) that caused a certain phenotype. What is the best ...
2
votes
1answer
32 views

Separation of closely-sized isoforms

I have to separate two proteins of 86kDa and 80kDa respectively, however, I just cannot get a decent separation even in 6% polyacrylamide gel. To make matters worse, these two proteins are isoforms ...
1
vote
1answer
74 views

Rosetta strain with chaperones for protein expression?

I am trying to purify a protein, and I was wondering if it is reasonably straightforward to obtain E.coli cells containing: -pGroe plasmids expressing chaperones. -Rosetta plasmids with codons that ...
-1
votes
1answer
79 views

How does a multicellular, eukaryotic body treat heat-resistant pathogenic bacteria?

How does the said body treat heat-resistant pathogenic bacteria? If fever is the body's response to foreign microbial invasion, then what happens if the bacteria is heat-resistant but the body's own ...
1
vote
0answers
114 views

General time reversible model of evolution and Felsenstein model

I would like to get suggestions for the books related to General time reversible model of evolution and Felsenstein model etc. Specifically the mathematical treatment of these topics and concepts ...
0
votes
1answer
31 views

Intro Bio question: dihybrid punnet square

Today we had our exam. There was a punnet square for two genes. and when I multiplied , for example, Ry × rY I wrote the answer as ...
5
votes
2answers
521 views

How does the eye know whether to focus further out or nearer in order to bring a blurry object into focus?

If the eye sees an object, but the object is out of focus, the eye could be focusing too near or too far. How does the eye (or the brain) distinguish one situation from the other? How does it know ...
7
votes
3answers
4k views

What makes DNA sticky-ends sticky?

When restriction enzymes jaggedly cut double stranded DNA it results in so called sticky ends. What is the substance that makes the DNA sticky?
2
votes
0answers
81 views

Modified Mendelian Ratios Problem

I'm studying modified Mendelian ratios. I've got a theoretical problem that I'm stumped on: A species of bird may have normal wings, or a mutation that causes frazzled wings. I do 15 identical ...
10
votes
2answers
282 views

Why do we have two of some organs, but not all?

We have two eyes, but we don't have two hearts. Why do humans have two of some organs, but not all?
4
votes
1answer
43 views

A few questions regarding immunology [closed]

I know that there is a variable region on antibodies which can recognize a wide variety of antigens, and that germinal centers create more "fit" antibodies to respond to an infection. So I was just ...
8
votes
3answers
135 views

If my brain lost all of its activity for a moment, would my memory be gone too?

I can't remember which question it was, but in the past here, it was explained to me that memory is actively stored in the brain, rather than "physically". Meaning, memories are made up of the brain's ...
2
votes
1answer
936 views

Why can't people talk while inhaling?

Why do we have to exhale in order to talk? From looking on Wikipedia, it seems like it has something to do with the glottis, but I'm not clear on the mechanism that makes speech sound so different ...
1
vote
1answer
49 views

Anesthetics, specifically inhaled anesthetics

I have had a look at previous inhaled anesthetics and many of them appear to be fluorocarbons. What could be the mechanism behind fluorine's anesthetic properties? Is it the specific bonding pattern ...
2
votes
2answers
76 views

Duration of selection and survival of the fittest

I feel there is a part of the theory of evolution I'm not understanding correctly or maybe I'm missing it, but would like cleared up. From what I understand, over time random mutations occur which in ...
9
votes
3answers
671 views

What causes feeling of feet falling asleep to be delayed?

This answer explains the sensation of extremities "falling asleep" as a result of sustained pressure on a nerve. The answer links to an external web page that says that the feeling "quickly goes away ...
6
votes
1answer
626 views

Why do some internal organs regenerate?

I have been reading about the human liver and zebra fish heart muscle having the ability to regenerate. It seems to me that these organs have very little chance to become damaged or worn out. At the ...
0
votes
1answer
32 views

If gene differs between chromosome pair does individual get a mixture of protein shapes?

Do diploids such as humans end up with a mixture of two different shaped proteins where the appropriate gene is expressed differently in the two halves of a chromosome pair or is there some governing ...
3
votes
1answer
100 views

What are limitations on the number of objects the eye determine at a glance?

Take two people Sam (average human) and Jack. Jack says to Sam "I'm going to show you some skittles (or other object) and I want you to tell me as quick as you can how many I'm holding." He opens ...
1
vote
1answer
87 views

(how) is it possible to choose the biological sex of a child? [closed]

I recently read of a study that investigated the ethics of child's biological sex choice in humans, and now I want to find out how this can/could be done. Does anyone know of scientific papers or ...
3
votes
1answer
257 views

How is satiety measured?

I am aware of satiety only through experience, rules-of-thumb and possibly myths. For example: white bread is not filling, a pasta meal can be filling but because we "burn" carbs quickly pasta itself ...
0
votes
0answers
58 views

Are ipratropium and tolterodine parasympatholytic?

They are nonselective cholinoblockers and antimuscarinic. Other cholinoblockers of parasympaticus, which I know, are parasympatholytic such as atropine, butylscopolamine, trihexyphenidyl, titropium ...
1
vote
1answer
132 views

Low copy numbers of plasmids

I have a plasmid with the P15A origin which apparently has a low copy number (see here). This would explain why my purification yeilds for subsequent digestion are low (gel shows the plasmid after ...

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