4
votes
1answer
69 views

Drosophila reference genome

Does anyone know the details about which line they are using to sequence as the Drosophila melanogaster reference genome?
9
votes
1answer
194 views

Black bumps on the cut surface of an avocado

I cut an underripe avocado in half and put half of it, without the pit but with the peel, in the refrigerator. A day later, I see very small black bumps along the cut surface. What are they? What ...
6
votes
1answer
115 views

Macromolecule levels in daughter cells after fission

When a prokaryote undergoes binary fission, how are the non-DNA macromolecules distributed between the two daughter cells? This is motivated by comments on a previous question and a G+ discussion. I ...
4
votes
1answer
105 views

Is there a correlation between incidence of type 1 diabetes and vitiligo?

Does the data indicate that if you have one, the probability of you having the other is higher than that of someone who doesn't have the one?
9
votes
1answer
422 views

Why does this illusion work?

This is another image I found on Google+ All lines are absolutely straight, parallel and perpendicular but why does it appear to have a curvature? Related: How does this illusion work?
3
votes
0answers
64 views

Are mature trees as susceptible to mutation from exposure to radiation as seedlings?

If a plant, say a ficus or a teak, as a sapling were exposed to radiation, and a tree of the same species were present at the same distance, which of the two would be more likely to mutate?
6
votes
1answer
84 views

DNA modifications other than 5-mC/5-hmC/5-fC/5-caC in vertebrate genomes?

Other than 5-Methylcytosine and the more recently discovered 5-Hydroxymethyl, 5-formil and 5-carboxylcytosine DNA modifications found in DNA sequences, what are other DNA modifications present in ...
1
vote
1answer
391 views

Is sperm contagious?

A person may have a cold or any other disease that is an airborne-infection. Is their sperm also contagious? Should the person take any precautions?
3
votes
1answer
48 views

Is there such thing as “biological cycles” of activity/performance/etc in mammals?

I'm looking for some information about the cycles of increased/decreased activity, mental performance or endurance that are related to a mammal's age and the time of a season. First of all, I'm not ...
7
votes
2answers
320 views

How to compute properties of peptides ?

I have been tasked with writing a program for computing properties of a give set of peptides. These peptides are given as 1-letter amino acid sequences and I need to compute the following : Length ...
5
votes
1answer
175 views

Cell proliferation limit and senescence of embryonic stem cells and fibroblasts

I am trying to understand the importance of proliferation limits and cell senescence. In particular, I would like to compare the proliferation limit of Embryonic Stem cells (ES) and fibroblasts (which ...
6
votes
1answer
289 views

Computational/mathematical models for predicting phenotype from genotype

Karr, Sanghvi, et al. (2012) propose a whole-cell computational model for predicting phenotype from genotype in Mycoplasma genitalium. Their model simulates myriad cell processes such as DNA ...
3
votes
1answer
75 views

Text/resource with information on all skeletal muscles and their motor units

Something analogous to an encyclopedia on baseball players with a list of all thier stats would be ideal. I'm not looking for just generic muscle names, locations and illustrations. Good answers ...
3
votes
1answer
97 views

Would a plant survive if it was watered using hard-water?

Hard water is water with high mineral/salt content. I'm told that a potted plant watered with a salt solution dries out sooner or later. Is this true? If so, would a plant survive if watered using ...
3
votes
2answers
228 views

Short-term Lamarckism in asexual single cell organisms

I was reading through the Karr et al. (2012) whole-cell computational model. One of the things they did was to induce single-gene disruptions in their model. They observed several to be fatal, but: ...
3
votes
2answers
214 views

Does body mass have a bearing on reflex speed?

A reflex is an unconscious action in response to some specific stimulus, e.g., blinking an eye, or pulling the hand away from a hot pin I know from school biology, and reading online that withdrawal ...
2
votes
1answer
2k views

What negative effects can pinhole glasses have on the body?

While shopping in the local supermarket yesterday, I was surprised to find this display on one of the shelves. I also realize that I should have taken a pamphlet with me, as well as a picture of ...
2
votes
1answer
620 views

Circulation through the liver in light of drug metabolism

I have a lingering question which stems from an answer that I gave to What hydrolyses aspirin within the digestive tract and blood stream? When a drug or any other substance is absorbed into the ...
6
votes
1answer
247 views

What are the white dots on the tree in this photo?

Today in Kongens Have, I noticed a lot of white dots on bark of trees. There are plenty of them, and they were usually on 'bottom' side of branches. Does anyone know what this could be? I took a ...
9
votes
2answers
136 views

What role does a protein's size have on protein-protein interactions?

Protein-protein interactions are when two or more proteins bind together, possibly for some important biological function. Recently, I'm starting to look more into proteins, and in particular, ...
8
votes
1answer
524 views

A timeline of the odds for survival for fertilized eggs and fetuses

I'm looking for data to build a timeline of the odds for survival of a fertilized egg, i.e., What are the odds it'll last a week? What are the odds it'll last a month? 2 months? (and so on ...
13
votes
1answer
929 views

How does evolution produce complex organs

I've been wondering lately how evolution manages to produce complex organs. It is pretty obvious to me how evolution would select some minor traits like size, resistnce to illness or climate. There is ...
8
votes
3answers
1k views

If body temperature is 37°C (98.6°F), why are most people more comfortable at around 21°C (70°F)?

It may be different for other people, but for me, anything above 32°C (90°F) is very uncomfortable, and my body is inclined to seek cooler temperatures. But I would think that at 32°C, the body would ...
1
vote
0answers
197 views

How do optical illusions work? [closed]

Hello fellow investigators I have two questions about optical illusions 1) A photo mosaic is something like this http://i.stack.imgur.com/Pzplp.png What are the optical principles behind our eye ...
6
votes
1answer
419 views

How and when did a dedicated immune system evolve?

I have recently been doing a lot of research into the interplay between the innate and adaptive immune systems in humans, and mammalian laboratory models. This has led to my reading some interesting ...
4
votes
1answer
87 views

Are there any situations in which phenylephrine is preferred to pseudoephedrine?

In the mid 2000s in the US, due to issues of drug enforcement, pseudoephedrine containing medications were brought behind the pharmacy counter and in most cases require ID, and phenylephrine was ...
6
votes
1answer
162 views

Genetic Diversity and Adaptation

I am somewhat new to evolutionary biology, having studied it on my free time as a computer science student. There is one particular thing that has always bothered me for which I have not seen a good ...
10
votes
2answers
194 views

How did the nucleobases in the Murchison meteorite form?

The Murchison meteorite is an important piece of evidence for abiogenesis, because it contained nucleobases from extraterrestrial origin, as this Wikipedia article explains. These results ...
5
votes
2answers
625 views

Why insects are so energy-efficient while flying?

Why are insects so energy-efficient while flying? Is it because of their light weight and aerodynamics or due to very efficient biochemical transformations (food->energy)?
2
votes
2answers
166 views

Do the simplest bacteria have ribosomes and helicase?

I find it interesting that all life on earth use DNA. I've seen video on how helicase and ribosomes work together to copy DNA sequences (to RNA) with helicase then recreate them using ribosomes. Does ...
8
votes
3answers
13k views

Why can't the brain and red blood cells use fuels other than glucose?

The question is rather straight forward: I have always been curious as to why, but cannot find an explanation online. I can imagine that the mechanism is different for each, but why does brain tissue ...
15
votes
2answers
4k views

Why is glucose our primary source of energy?

Is there any evolutionary reason for glucose being the "main" molecule used as a source of energy, beginning with glycolysis and subsequently cellular respiration (after being converted to two ...
10
votes
1answer
176 views

Does stress physically age our body?

Going by the assumption that stress eventually triggers a flight/fight response, and the subsequent realization that flight/fight puts the body in a system of readiness to use it's available resources ...
3
votes
7answers
424 views

Introductory books about evolution

This days I read some debates on evolution. That made me more interested to read something reliable on topic - I mean books. I'm christian - although I think it doesn't matter on that topic - and I ...
7
votes
1answer
67 views

Sequence of ribosomal RNA

Is it possible to sequence rRNA directly, that is, using the ribosome rather than the DNA from the nucleus? For example, this paper, Complete nucleotide sequence of a 16s rRNA gene from E. coli, ...
8
votes
1answer
238 views

How do the pharmacodynamics of the NSAIDs differ and are there “resistant” COX phenotypes?

I know that the non-steroidal anti-inflammatory drugs (e.g., aspirin, ibuprofen, naproxen) affect the enzymes cyclooxygenase (types I and II). Is there any difference in the degree to which these ...
7
votes
5answers
326 views

Why is the human body able to repair a broken bone and not a heart muscle?

The human body can repair skin/organ laceration, fractures, even repair nerves - albeit the duration and rate of recovery differ. For instance: The burn scar on my arm from the hot soldering iron ...
1
vote
0answers
23 views

Are open grounds in the vicinity of new construction more prone to waterlogging? [closed]

In my experience as open grounds are paved over by new concrete work other grounds yet open are proportionately more water-logged after heavy rain. Over time trees in such water logged grounds too die ...
7
votes
1answer
122 views

How does Yeast-two-hybrid detect interactions between several proteins in one experiment?

I am trying to understand the Y2H screening method. I can understand how we can check if two specific proteins interact with each other. For example, if we want to check whether protein A and protein ...
4
votes
2answers
229 views

What is the proper quick freezing /snap freezing protocol for pancreatic tissue?

I would like to do a quick freeze on pancreas from mice. I want to then make sections (30 µm thick). The idea is to preserve a fluorescent staining done in vivo. I do not know if I should place my ...
3
votes
1answer
87 views

Predictable microchimerism

I read in New Scientist recently that microchimerism occurs between previously born siblings and grandparents, not just the mother. Do we know which parts of the genome are likely to be transferred? ...
3
votes
2answers
183 views

How do I create a probe for in situ hybridization?

I tried to make the probe several times but it failed again and again. It usually turns out that the probe after hydrolysis is very very short (maybe around 50nt). I did not check the RNA before ...
4
votes
1answer
437 views

Lifespan of connective tissue cells

This post is regarding a follow up on my initial post on "Properties and life cycle of chondrocytes and tenocytes". I am elaborating on my question on the lifespan of tenocytes and chondrocytes. ...
6
votes
2answers
271 views

Intrinsic apoptosis in erythrocytes

With a lack of mitochondria, can red blood cells perform intrinsic apoptosis and do they have another way of generating cytochrome c to attach to a CARD domain and assemble the apoptosome? Or are ...
10
votes
1answer
92 views

Are rods/cones rejuvenated periodically?

Pretty much what the title states. Some cells/structures in the human body undergo rejuvenation periodically by flushing away older cells and growth of new ones. E.g Skin, Blood Does this (for want ...
3
votes
2answers
356 views

JMol “calculate HBONDS”: which atom is the donor/acceptor?

JMol can be used to identify Hydrogen bonds in proteins by the script "calculate HBONDS". By outputting the state of the network, we can obtain a lisdt of H-bonds. Here's one line from an example ...
3
votes
1answer
69 views

What's in a Name: Statistical Genetics

The novice often performs population calculations using what is referred to as Mendelian Genetics. Soon after the publication of Mendel's results; Hardy and Weinberg presented their results after the ...
4
votes
0answers
55 views

Does a mydriatic drug neutralize the action of a miotic?

If a person were administered a mydriatic, would the subsequent application of a miotic neutralize the action of the former? If the sequence were reversed would a mydriatic neutralize the effect of a ...
10
votes
2answers
171 views

Is there an “evolutionary species similarity calculator”?

Is there a website where I can input pairs of species and get an "evolutionary similarity score"? E.g. (numbers are completely made up) Input: Chimp and Human, Output: 97% Input: Cat and Human, ...
3
votes
1answer
165 views

Negative feedback in the fructose metabolism in liver

What happens in liver when large amount of fructose is consumed? I vaguely remember my biochemistry lecturer telling us that the enzymes that process fructose in the liver does not have negative ...

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