0
votes
0answers
14 views

Is PTB ECG Diagnostic Database AAMI standard?

The PTB database can be found here. There has been only one publication about the database in the recent 15 years which list challenges in the database. You can review the ECGs (electrocardiogram) ...
0
votes
1answer
62 views

Simplest Biological Organism? [duplicate]

What is the simplest biological organism from which a DNA sample has been or could be obtained? Could the resulting DNA be processed and examined in such a way that the resulting information would ...
0
votes
1answer
74 views

Parallel Autonomic regulation of Cough and Runny Nose

I describe here the serous inflammation of runny nose. Cough is mediated by Cough center. I think Runny nose is also controlled by the autonomic nervous system and probably by some reflex. Assume ...
0
votes
1answer
27 views

Which ionic channels of Pacemakers can work in very low frequencies in extrasystole?

At frequency 0-3 Hz. Like computer processors which can work at low frequencies and controlling under- and overvoltage. Normal most significant channels are Ca2+ and K+ that are changing. However, I ...
0
votes
1answer
34 views

Manifestations of open foramen ovale in adults

I read that foramen ovale opens in 30% of adults. I do not know how much of these openings can then close again. Probably, none. It is not pathogenic if no symptoms. It allows blood to enter from ...
25
votes
4answers
6k views

What does the human body use oxygen for besides the final electron acceptor in the electron transport chain?

My biology teachers never explained why animals need to breathe oxygen, just that we organisms die if we don't get oxygen for too long. Maybe one of them happened to mention that its used to make ATP. ...
18
votes
2answers
482 views

How is menstruation not suicide in the wild?

Watch any wilderness special for more than a few minutes, and you'll notice a familiar pattern: when a predator catches the scent of blood on the wind, the hunt is on. Wounded animals make the best ...
18
votes
3answers
1k views

How does the immune system “learn” from a vaccine?

According to Wikipedia: A vaccine typically contains an agent that resembles a disease-causing microorganism, and is often made from weakened or killed forms of the microbe, its toxins or one ...
14
votes
2answers
168 views

Relationship between our microbiome and personalized nutrition

Recently, it has been asked whether there are 'metabolic types' between humans that can benefit from a sort of personalized nutrition. One answer suggested that one discerning factor could be the ...
14
votes
1answer
3k views

How does a plant grow before photosynthesis is possible?

During photosynthesis, a plant translates CO2, water and light into O2. I assume the carbon C is further used for the growing process. I wonder how the plant grows before the time where photosynthesis ...
14
votes
3answers
3k views

What causes the development of antibiotic-resistant strains of bacteria?

I understand bacteria have become resistant to antibiotics due to selection pressures, but how do resistant bacteria process antibiotics when exposed to it, compared to non-resistant bacteria. Also, ...
13
votes
0answers
1k views

Why do we experience temperatures below 37 degrees Celsius as 'hot'? [duplicate]

We always prefer to be in 20-25° C, although our core temperature is about 37°? Why is our skin temperature lower than our core temperature?
13
votes
2answers
1k views

Is the EC50 of an activating protein for an enzyme a good indicator for the binding affinity Kd?

We work with a membrane protein system where measuring the affinity between the enzyme and the upstream activating protein has been difficult, and when measured in detergent solution, it is almost 100 ...
13
votes
2answers
4k views

How will rising carbon dioxide levels in the troposphere affect photosynthetic producers?

Much discussion has been had about the affects of climate change on plantlife, but how will rising carbon dioxide concentrations affect the photosynthetic process itself? Since CO₂ is a reagent in ...
12
votes
1answer
265 views

Is the human biological clock genetically programmed or learnt?

Argument favouring learning: A newborn sleeps for 20-22 hours. But overtime (s)he learns to focus sleeping time to night time, according to his or her needs and family needs. Some sleep from 1 am to 7 ...
12
votes
3answers
11k views

How many agarose gel bands are typical for circularised DNA

I am aware that circular DNA can be both relaxed and super coiled. However when running an agarose gel of the circular plasmid along with singly digested plasmid with BamHI and HindIII, I see 1 band ...
12
votes
2answers
211 views

Can DNA produce ribozyme-like structures?

RNA is known to act as an enzyme via its ability to fold itself in specific ways. Is DNA capable of such structures? Or is it some biochemical reason stopping the folding? Have they been observed in ...
12
votes
3answers
1k views

How did the huge dinosaurs cope with gravity and loads on bones, etc.?

It's very costly to be a huge animal. Your mass grows in cube when you scale up, but you still only have two/four legs to support the same weight. This increases the pressure that your body needs to ...
12
votes
2answers
410 views

Are there any plants that fix their own nitrogen?

I know that most nitrogen is fixed through industrial processes and bacterial symbiotic relationships. However, are there any plants that can fix their own atmospheric nitrogen?
12
votes
1answer
220 views

Abiogenesis: Beyond the research journals as a lead in to discussions on evolution

I just came across this abstract: Aminoacyl-tRNA synthetases (aaRSs) are responsible for creating the pool of correctly charged aminoacyl-tRNAs that are necessary for the translation of genetic ...
11
votes
1answer
161 views

Are there specific conditions that allow humans to see ultraviolet wavelengths

It is fairly common knowledge that the lens in its normal state absorbs ultraviolet (UV) radiation. An interesting notion has come up from time to time in my reading that suggests there are a small ...
11
votes
1answer
848 views

Is there an evolutionary advantage to crying when sad?

It seems as though the act of crying when sad does nothing to relieve that sadness. Is there an advantage to crying from an evolutionary perspective, or is it the end result of a different process? ...
11
votes
4answers
1k views

Has there ever been an attempt to create nutritionally tailored food for adult human consumption?

For all domestic animals, and for all animals kept in laboratory, complete and precise composition of perfect food is figured out (cat food, dog food, cattle, rats, laboratory monkeys and apes) -- ...
11
votes
2answers
391 views

What are the evolutionary niches differentiating an apple from a pear?

So, as far as I understand (basic) evolutionary theories, diversity is generated by "niching." That is, if there is an environmental factor that hasn't been fully used by any species to "profit" off, ...
11
votes
1answer
681 views

How do I get the current “camera position” in PyMol so I can reuse it in scripts?

I have a few protein models I want to take pictures of with various ligands bound. It would be nice if I could do it from the same "position", but the only way I can figure out to repeat the same ...
10
votes
3answers
1k views

Why deoxyribose for DNA and ribose for RNA?

Why is DNA made out of deoxyribose and RNA made of ribose? Why can't they both use ribose or deoxyribose? I think that the deoxyribose gives an advantage in storing genes, the job of DNA and ribose is ...
10
votes
3answers
403 views

Athletes: nature vs. nurture?

Having watched a lot of olympians the last few weeks, I was struck by how many of them have actually spent their wholes lives/careers training for their one event (be in running a marathon, or ...
10
votes
1answer
604 views

Is there are evolutionary explanation for why humans and primates are ticklish? How might it have evolved?

Tickling is a rather interesting phenomenon: When humans or apes are touched in certain areas like the armpits or sides, we respond with laughter AND frantic attempts to stop the assault. Obviously ...
10
votes
3answers
1k views

DNA synthesis companies: cost per base, turn-around time, codon-optimization algorithms

I would like to synthesize a 3.4kb gene (originally isolated from soil bacteria) and transform it into E. coli. There are several companies (DNA2.0, GeneScript, BlueHeron) which will synthesize the ...
10
votes
1answer
350 views

Can Naegleria fowleri enter through wounds into the bloodstream?

All the sources I've read said that Naegleria fowleri enters the brain through the nose. But lets say that someone had cuts on their arm or leg and they are swimming in water that is conducive to ...
10
votes
1answer
133 views

What portions of the brain have drastic changes in activation when we “sense” someone is there?

I was watching an old Arnold Schwarzenegger movie ("Commando") where he plays an elite soldier (surprise). An enemy tries to sneak up on him, and Arnold says that he smelled the other guy ...
9
votes
1answer
210 views

What senses are active while sleeping?

During sleep, our body activity decreases. I am wondering on the extent of the lowering of this activity regarding our five senses. Clearly, the sense of touch is still very efficient since shaking a ...
9
votes
1answer
760 views

Why do dog's eyes glow green on a photo?

Taking my current profile picture as a prominent example: This photo has been taken with flash. As I gather, this is the same effect that makes a human's eyes glow red on photos, namely the ...
9
votes
1answer
270 views

What's the smallest size a human eye can see?

During a biology experiment at school, where we would look at waterweeds under a microscope, my teacher said something about that it's impossible for the human eye to see the cells without a ...
9
votes
2answers
2k views

Why can't neurons undergo cell division?

Many cells in the human body can divide and reproduce, making healing possible. Neurons, however, cannot reproduce, which makes diseases affecting the brain particularly crippling. Why can't neurons ...
9
votes
2answers
4k views

Why does it hurt when you take sweets, if you have cavities in your teeth?

When you have cavities in your teeth taking any sweetend drinks or food causes sensitivity or pain. What could be the reason?
9
votes
3answers
121 views

Standard letter for 5-methylcytosine

I'm working on a piece of software that computes melting temperatures for nucleic acid duplexes, and I'm about to add support for 5-methylcytosine as a nucleotide base. At the moment, the bases ...
9
votes
1answer
2k views

Why is GTP gamma S non hydrolyzable?

GTP gamma S is routinely used in studies of G proteins to stably activate the G protein. Comparing the structures of GTP gamma S and GTP, the Sulphur atom replaces the Oxygen attached to the leaving ...
9
votes
3answers
395 views

Source of DNA sequences

I'm working on a project where I am taking DNA sequences and translating the codons into musical notes. I have some good ideas of how to do this, I'm just not sure what sequences to work with. My case ...
9
votes
1answer
369 views

How are there alternative initiation codons?

According to wikipedia and the original complete sequence of the K-12 genome, there are multiple non-AUG start codons such as GUG and UUG. How is this possible? I'm particularly curious about the ...
9
votes
1answer
1k views

What's the effect of oxygen deficit on plants?

As I know all cells require oxygen. So my question is how efficiently can plants operate in no-oxygen atmosphere? Do all plants produce enough oxygen for themselves? Can they consume their own oxygen ...
9
votes
2answers
142 views

Acknowledging differentiation of species, in historical times

This is at least partly an historical question, and I am not even remotely a biologist of any sort, so apologies beforehand if it's a little obscure. I often wonder how many distinctions were made in ...
9
votes
4answers
1k views

What determines a successful protein expression in E. coli?

Some proteins express well in a heterologous host; others- don't. A few requirements are known to determine the protein expression, like a strong promoter (like T7) for transcription and a strong ...
8
votes
1answer
101 views

Why do humans hear better between 2kHz and 5kHz?

I've recently seen the following image: Source: https://commons.wikimedia.org/wiki/File:Hoerflaeche.svg Translation (from German): The upper boundary (Schmerzgrenze) is where it starts to hurt ...
8
votes
1answer
785 views

Does a bigger breast give creamier milk?

It is fairly common for a woman to have one breast larger than the other. I have also heard that, for a breast feeding mother it is common for one of the breasts to yield a creamier milk whilst the ...
8
votes
1answer
166 views

How should I feed and keep an ant queen?

I have captured wandering ant queen. I guess she was just fertilised and was looking for a place to start a hive. I'd like to create my own ant hive in artificial environment. I unfortunately only ...
8
votes
2answers
1k views

Why do I need a flu shot every year, while many other vaccinations last years or even a lifetime?

Is it a viral vs. bacterial thing? Is there just more variety among types of flu than other diseases, so that this year's vaccines don't cover next year's flu?
8
votes
3answers
6k views

Does our DNA change during our lives?

As far as I know, DNA is the construction protocol of all organisms on Earth. Does it change when influenced by time and environment (physical laws)? As parents with schizophrenia are more likely to ...
8
votes
2answers
2k views

why is AUG the initiation codon?

Is there any reason why AUG is the initiation codon ? Why is there a need for an initiation codon ? Can't translation start with different codons?
8
votes
1answer
12k views

What is the composition of human feces?

Are there any studies or general information on the composition of human feces? I'd specifically like to know the percentage of carbohydrates and amino acids relative to the amount that was ingested ...

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