1
vote
1answer
291 views

What are the differences between HPRD and BIOGRID databases?

What are the differences between HPRD and BIOGRID protein-protein interactions databases? What are their purposes? Why do we need two different databases? How is data collected into each one? How ...
1
vote
1answer
176 views

List of all reported bacteria

I would like to know were to download a table file with all reported bacteria and its corresponding PHYLUM, CLASS, ORDER and FAMILY. Basically, its the same table than this one from GOLD genomes but ...
0
votes
1answer
56 views

Looking for raw cell videos from a light microscope

First off, I'm not looking for online lectures. I am trying to find creative commons licensed videos of live cells moving around without annotation or anything extra. I would prefer a few minutes of ...
0
votes
1answer
65 views

bioinformatics /genomics [closed]

i am looking for likely truncation sites to prove recombination in sequences. i have 4 sequences. i believe one to be the "real sequence" and the other 3 to be recombinants caused by cleavage possibly ...
3
votes
3answers
44 views

Immune reaction to “new” protein

I read in Bruce Alberts Molecular Biology of the cell : Normal mice,for example, cannot make an immune response against one of their own protein components of the complement system called C5. ...
2
votes
2answers
340 views

How to know if a woman is fertile without actually making her pregnant?

How to know if a human female is fertile (can give birth to child in future) without making her pregnant? Any signs, tests?
3
votes
1answer
34 views

Manufacturing toxoids

Toxoids produced by tetanus and diphtheria bacteria are detoxified with formaldehyde, yet their antigen properties remain. Source : Biological Science by Taylor What does formaldehyde do ?
17
votes
3answers
267 views

What is the reason behind choosing the reporter gene when experimenting on your gene of interest?

I noticed within example experiments in class that different reporter genes are chosen to be inserted near your gene of interest to prove whether or not the gene is being expressed. For example, you ...
1
vote
1answer
84 views

Niche overlap Index

I wanted to use the compana() function from the adehabitat package. I don't really understand the meaning of the data in the ...
3
votes
3answers
121 views

Can humans be printed?

Is it possible to spray stem cells on fully grown skeleton to get fully grown humans? Currently, just read about recent advances, and wondered if something like this is possible.
2
votes
1answer
201 views

Why is cyanide poisonous?

I know cyanide inhibits complex IV in the electron transport chain, but I don't understand why this makes it so toxic. If cyanide is bound to the complex, can't the electrons just bypass it and ...
0
votes
2answers
180 views

Is there any genetic similarity that defy evolution theory?

For example, say species A is common ancestor of B, and C. Species B is a common ancestor of D and E. We would expect that there will be more genetic similarity between D and E than D and C. And ...
2
votes
1answer
82 views

Determining sequence of oligoribonucleotide

Oligoribonucleotide X was treated with phosphatase (for removal of 3' and 5' - terminal phosphates), then with RNAase T1, which cleaves all phosphodiester bonds located in a 3' position of ...
1
vote
2answers
123 views

Would it be correct to state that any biological difference between the sexes has to be found in the Y chromosome?

If the reason Why Men Don't Listen and Women Can't Read Maps is genetic, then one of the genes in the Y chromosome is to blame and in theory could be identified. Correct or incorrect?
2
votes
1answer
324 views

What are the visual, behavioral similarities and differences between Yellow Fever Mosquito (Aedes aegypti) and the Tiger Mosquito (Aedes albopictus)?

The Tiger and Yellow Fever Mosquito visually look very similar. Recognizing the difference is important for tracking and controlling the spread of Yellow Fever, Dengue fever and other diseases. ...
2
votes
2answers
647 views

Are there genetic similarity between humans and pigs that don't exist in chimps?

Chimps are our closer relative. Any genetic similarity between humans and chimps must exist on the common ancestor. Pig branch out sooner. So, any genetic similarity between humans and pigs must be ...
1
vote
2answers
377 views

Histidine - why essential for children?

Why is histidine an essential amino acid for children but not for adults ? What changes in the body occur which lead to the formation of histidine in adults but not in children ? What causes these ...
4
votes
2answers
177 views

Plant identification?

Can anyone identify the plant below? It's in a backyard in Pennsylvania, and the photo was taken today.
3
votes
1answer
99 views

When might an inhibitor of bacterial transformation be useful?

I am part of a project elucidating some structures that are required for bacterial transformation. We have the opportunity to screen inhibitors of the system to stop it from functioning. I am not a ...
2
votes
1answer
59 views

Mutation in pre-mRNA sequence

Has there any mutations been recorded which cause harmful effects due to change in the part of pre-mRNA responsible for proper m-RNA splicing ?
5
votes
3answers
199 views

How easy is it to carry out de novo sequence assembly?

Today a colleague of mine asked the following question: " Assuming I need to build from 0, a chromosome of a fish, with short reads but no other reference whatsoever [de novo assembly]: ...
3
votes
1answer
156 views

What is the most genetically simple organism except viruses?

What is the most genetically simple organism (except viruses) on this planet? By simple I mean the least number of genes.
0
votes
1answer
61 views

How do transplanted stem cells find their way to bone marrow?

Miraculously, transplanted stem cells find their way to the bone marrow missing the stem cells. How do they achieve this?
-4
votes
1answer
86 views

Basic definitions for biology terminology [closed]

I am currently writing a mathematical biology paper, however it is very hard for me to follow the existing literature due to specialized terms. I have tried googling but most explanations are very ...
4
votes
1answer
121 views

pfu Turbo DNA polymerase AD

What is the duration (Life") of pfu turbo DNA polymerase AD. I am trying o Amplification a 3.3kb fragment and the PCR schedule is 6 hours long. The manufacturers notes just specify that its activity ...
1
vote
0answers
55 views

What is the cause of singularity in phase response curve of human sleep and bright light?

I have no background in science as I am a computer programmer, but I am trying to get information on phase response curves, human sleep and exposure to bright light as I am trying to get to grips with ...
3
votes
1answer
100 views

How can this bird be identified? Can someone please identify this bird?

These photographs have been taken in Warora, India. Could someone please help identify this bird?
4
votes
1answer
68 views

What evidence is there on the medical effects of circumcision?

If this is the wrong place to post this question, then I will delete it and post it were it belongs. I have heard many conflicting things about circumcision. I have heard that it reduces the rate of ...
5
votes
1answer
168 views

What about 23andMe's SNP test gives it such bad efficacy as a diagnostic tool?

The recent news about the FDA stopping the google backed 23andMe service selling any more kits got me thinking. I understand the company may have been selling it as a medical tool prematurely, but ...
1
vote
1answer
172 views

What type of mutation causes Progeria?

I'm doing my High School biology final on Progeria, and am wondering what type of mutation causes this disease. I know that the LMNA gene codes for the "prelamin A" protein, and that protein contains ...
1
vote
1answer
63 views

Clarification of the procedures to amplify cDNA needed

The typical procedure to obtain cDNA from genomic extracted DNA is the following: RNA is extracted from desired tissue, RNA/DNA hybrid is obtained by virtue of reverse transcriptase RNA dependent DNA ...
4
votes
1answer
52 views

Finding RNA Loops

I was rooting through the literature, but there is too much work on the topic of detecting loops in RNA and the RNA helices that go with them. Can anyone point to a good review on this topic or even ...
2
votes
1answer
30 views

Difference vector target and genomic target

In Pfu turbo DNA Polymerase AD information sheet (and possibly in many other) different amplification targets are divided in Genomic DNA targets, Vector DNA targets and cDNAs. What is the difference ...
0
votes
1answer
311 views

Static in limbs

I have noticed that while sitting in the Sukhasan posture(picture below) for a long time, my feet suddenly become all stiff and i am unable to move it. What I deduce from the experience is that it is ...
22
votes
4answers
10k views

How many genes do we share with our mother?

Somewhere I have read we share more than 99% of our genes with every other other person and 98% of our genes with chimpanzees. What does this mean? Don't we share 50% of our genes with our mother and ...
4
votes
0answers
266 views

Statistical Coupling Analysis (SCA) to identify coevolved residues: use of ICA [closed]

We've begun to try out the SCA Matlab toolbox (latest version) downloaded from Dr. Rama Ranganathan's website, and, following the included tutorials, would like to apply it to our protein family. The ...
4
votes
1answer
3k views

Under what conditions does the body burn fats, proteins and carbohydrates?

Searching the internet, I have found lots of conflicting information from various fitness sites concerning when the human body burns fats, proteins and carbohydrates. My basic understanding was that ...
1
vote
0answers
22 views

mixing beer with spirits, increase alcohol content? [duplicate]

I decided to mix beer with vodka hoping it would make me more drunk due to the alcohol content but then remembered the rest ISNT alcoholic and i cant figure out if mixing beer with vodka or other ...
1
vote
3answers
431 views

What does orbital mean in orbital frontal cortex?

Orbital frontal cortex is where decisions are made. What does the word orbital there mean? I looked around in wikipedia and never find it.
3
votes
2answers
81 views

Why not use Cu(OH)2 as a dye for protein electrophoresis?

As I know, $Cu(OH)_2$ $+$ Protein $\rightarrow$ Purple. So why not use $Cu(OH)_2$ as dye in protein electrophoresis?
2
votes
1answer
62 views

Why is Thermus aquaticus and Taq Pol stable?

What is the molecular basis of the stability of the bacterium Thermus aquaticus and the enzyme Taq Pol it produces ? I have tried googling this but did not get a good answer.
1
vote
1answer
123 views

How is deviated nasal septum related to cold

I have a deviated nasal septum and I always suffer from common cold I was just wondering how a deviated nasal septum can be the cause for chronic common cold
5
votes
2answers
872 views

Isotype control antibodies in Flow Cytometry

In a Flow Cytrometry, one can add an Isotype Control Antibody to allow another antibody to bind more specific to the cells. My question is, how can the Isotype Control Antibody add specificity to the ...
5
votes
1answer
52 views

Is there any evidence telling us what the oxidation state of early earth's atmosphere was?

I ask this question in relation to the origin of life. I realise it would probably be better suited to a geology stack exchange, but it does not yet exist. The Miller-Urey experiment gives a lab ...
0
votes
1answer
128 views

Does avocado and orange have a common ancestor?

While I'm eating my orange, I felt as if I was eating avocado. It might be genetic manipulations perhaps but it made me think if they have a common evolutionary ancestor. Is there?
4
votes
2answers
1k views

The number of nipples (breasts) a species has?

Only mammals have mammaries and mammary glands. What evolutionary factors determines the number of mammaries (nipples/teats/breasts) a species has? Is it always an even number?
2
votes
1answer
559 views

Excretion of various wastes and water requirement

A common fact is that Ammonia, Urea and Uric acid are the most common excreted metabolites and their removal needs varying amount of water, highest for ammonia (hence suited only for aquatic animals) ...
2
votes
3answers
240 views

Bacterial cell lysis buffer used in proteomics procedures

What kinds of detergent-free bacterial lysis buffers exist? The proteins we're extracting will be later analyzed by LC-MS/MS, and we're looking for a lysis buffer that won't interfere with this ...
6
votes
3answers
6k views

What is the distinction between chemokines, cytokines, interferons and interleukins?

They all seem to describe molecules of similar function and many people seem to use them interchangeably. Also please include any other similar molecules if I've forgotten any in the list above.

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