2
votes
2answers
207 views

Is consuming sugar with food as beneficial as consuming glucose (~half of the amount of sugar)?

A few years back I heard at biology class that sugar's molecule consists of half the number of elements of a glucose molecule. So not counting the energy needed to transform two sugar molecules in one ...
9
votes
1answer
1k views

Why are some berries poisonous?

In my understanding, the evolutional function of berries is to be eaten and pood out somewhere else, so that the seeds of the plant spread. Is this so? Then why are some berries poisonous?
5
votes
1answer
130 views

Phenotypic Variation of cattle - looking for academic sources

Can someone please point me in the direction of a good academic article on the following: What are possible sources of phenotypic variation of different 400 day weights of cattle? Furthermore how ...
3
votes
1answer
178 views

What is the relationship between Homocysteine and Norepinephrine metabolic cycles?

I've been researching neuromodulators and have taken a look at the Norepinephrine/Noradrenaline system. The diagram of biosynthesis of Norepinephrine is presented in the wikipedia article: ...
12
votes
2answers
4k views

Do men have significant hormonal cycles?

I know there's a similar question here. But that discussion dissolved into lunar cycle and a correlation with it. I want to find more towards the original question of is there a periodic hormone ...
4
votes
3answers
141 views

Robotic surgery for treating cancer?

We can localise cancer cells in the body. We can manufacture materials thin and hard enough to penetrate the body without harming it. So what stops us from creating an automated surgery where the ...
2
votes
1answer
198 views

How to learn DNA Origami

Can you tell me is there any good softwares and tutorials which can be used to learn DNA Origami. I am new to this and want to learn from basics. Advance thanks for your help edited: INSILICO
12
votes
2answers
195 views

Can a color-deficient person be made to visualize the missing colors?

Hope this is within the scope of this site. Color-deficient persons lack the cells in their retina needed for differentiating some (or all) colors. However, the part of the brain that actually ...
5
votes
1answer
64 views

on/off behavior of neural networks

What causes a group of disembodied neurons in a dish to fire after a silence? If there are no neurons providing a stimulus for more firing (as in a dish of disembodied rat neurons), then why don't ...
0
votes
1answer
445 views

Is breathing in deodorant fumes dangerous for my brain?

I noticed that I sometimes get dizzy when I accidentaly breathe in too much Axe. Also, I find the smell of alchohol rich deodorants quite unpleasant. But, I was wondering, is it actually dangerous? ...
5
votes
1answer
121 views

Mutation-immunity in Luria-Delbruck experiment

If experiments like those of Luria and Delbruck on E. coli and T1 phage are the main source of our confidence in the mutation-immunity model, is it then highly unlikely that there are other types of ...
10
votes
1answer
308 views

Foveal ganglion cell density (Tay-Sachs Disease)

I’m currently reading on Tay-Sachs disease and have stumbled upon something regarding the typical “cherry red” macula symptom. On the one hand it is mentioned that the macula is almost devoid of ...
3
votes
0answers
95 views

Terminology question: the scope of an allele in an organism

Let us consider a gene FOO with novel type foo. If I were discussing an organism that has inherited foo in every cell during classical zygote formation, then I would ordinarily just say that the ...
0
votes
1answer
220 views

From which ancestor species did humans inherit orgasm?

From what ancestors did humans inherit orgasm? Do fish experience orgasm? Are the male and female orgasm the homologues that can be traced to the time when there was no difference in sex between ...
5
votes
1answer
356 views

What are good practices with reusing desalting columns

At least according to a few sources Prozyme and Protocols-Online, it is possible to reuse desalting columns and since I'm cheap I would like to also. Key things seem to be washing with several column ...
5
votes
2answers
1k views

What would cause proteins to get stuck in the stacking layer of a SDS-Page gel

Typically when proteins aggregate, they will get stuck at the top of the well. However, we're seeing some protein aggregate in the stacking layer even when we're treating the loading volume with DTT. ...
1
vote
1answer
72 views

Expression of an ancesteral gene

Why would the expression of an ancestral gene and comparing the product to a modern protein give misleading conclusions about heredity? Update: By ancestral gene I mean a gene which was used by an ...
6
votes
1answer
82 views

If a non-mammal is starved of oxygen for some time, how long would it take the animal's neurons to die?

This is a follow-up question to Why do neurons die so quickly (relative to other cells) when deprived of oxygen?. I'm particularly interested in the case of reptiles, octopuses, and other ...
4
votes
1answer
1k views

What is a focal copy number variation?

Often, genetics studies, especially genome wide ones, talk about "focal copy number variations" in genes or regions of the chromosome. I know what a copy number variation is. What does "focal" mean, ...
4
votes
1answer
536 views

Why are omega-3 fatty acids so easily oxidized when they're incorporated in cellular membranes?

Apparently, this has led to results with clinical significance, as we can see at http://extremelongevity.net/2011/10/03/daily-fish-oil-consumption-may-reduce-lifespan/... The researchers fed a ...
6
votes
1answer
115 views

Macromolecule levels in daughter cells after fission

When a prokaryote undergoes binary fission, how are the non-DNA macromolecules distributed between the two daughter cells? This is motivated by comments on a previous question and a G+ discussion. I ...
4
votes
1answer
139 views

Non-monotonic knock-out effects in prokaryotes

Typically, when performing gene-knockout, the experimenters select one gene to remove/replace-with-junk and then see if the prokaryote can still undergo fission. If it continues to reproduce then the ...
8
votes
3answers
12k views

Why can't the brain and red blood cells use fuels other than glucose?

The question is rather straight forward: I have always been curious as to why, but cannot find an explanation online. I can imagine that the mechanism is different for each, but why does brain tissue ...
5
votes
1answer
287 views

Where can I find the tissue-specific protein expression levels for hTERT (telomerase subunit)?

I find a number of contradictory sources regarding the tissues in which hTERT - the protein - is expressed. Does anybody know some resource that authoritatively (as authoritative or widely-accepted as ...
5
votes
3answers
245 views

Biological Pathway of Lipid Hypothesis

I've read a lot on both sides of the debate of low carb vs low fat diets trying to make some sense of what is being proposed. The lipid hypothesis runs roughly along the lines that we have lots of ...
6
votes
2answers
65 views

Predicting and identifying microbes and enzymes DNA sequence with metabolic prediction

Presently I am working on metagenomics of coal biomethenation by bacterial consortium. I have got the sequence result (Illumina). The sequence is huge and I can't predict anything from the sequence. ...
4
votes
1answer
356 views

What phenotypes can arise from gender-related aneuploidy?

Humans normally have 46 chromosomes (two copies - one from each parent - of each of the 24 chromosomes: [1:22] + [XX or XY]). Aneuploidy is an abnormal number of chromosomes - Down's syndromes is an ...
4
votes
1answer
97 views

In a vertebrate chimera, are particular organs homogenous genetically?

I have read that a chimera is an organism with two or more sets of DNA, with every cell having one of the sets. Is it possible and common for the two or more sets to be present in the cells of a ...
12
votes
1answer
254 views

Evolution of long necks in giraffes

In this question, the OP uses giraffe necks as a supportive example of evolution. Is the mechanism described in this post accurate? At some point, I thought I remember hearing that giraffes did not ...
8
votes
2answers
296 views

Do antibiotics attenuate immune response on subsequent exposure to same bacteria?

A healthy immune response to a bacterial infection includes "memory" to permit the body to thwart subsequent exposure to same bacteria. What are the dynamics of using antibiotics on initial exposure ...
4
votes
1answer
152 views

Vigorous shaking for HFR interrupted mating

I am trying to reproduce E. coli interrupted mating using an HFR strain, and I read that the cultures should be vigorously shaken at times to interrupt the DNA transfer from the F+(HFR) donors to the ...
14
votes
2answers
806 views

Impact of Alan Turing's approach to morphogenesis

Shortly before his untimely passing, the computing pioneer Alan Turing published his most cited paper The Chemical Basis of Morphogenesis (1952). The central question for Turing was: how does a ...
3
votes
3answers
173 views

What Defines a Food as Edible?

With many foods today containing chemicals, agents and preservatives etc... What biological criteria must a new food and its constituent components satisfy biologically, to be defined as edible? ...
7
votes
2answers
151 views

How was the guided daily amount (GDA) calculated?

We are constantly shown nutritional information on food packaging stating this food contains "x" amount of your guided daily amount. A linked to the values is here. How were these values calculated? ...
11
votes
3answers
1k views

What happens to dextrorotatory amino acids in humans?

As indicated by this question, most of the amino acids in the human body have the L-chirality. As enzymes also have handedness, what happens to the D-amino acids that end up within the human body? Are ...
9
votes
2answers
318 views

Do twins “run in the family”?

My wife and I recently found out that we are going to have twins and so nearly everyone asks if we have a family history of twins. Now I know that the answer for me is that it doesn't matter—as ...
4
votes
1answer
1k views

What does vitamin B6 and B12 absorption depend upon?

I'm looking at my question about homocysteine metabolism and am doing a followup inquiry into vitamins B6(Pyroxidine) and B12(Cyanocobalamin). I've found this interesting bit about vitamin B12 and am ...
3
votes
1answer
697 views

How long can a unicellular organism live without nutrition? What happens after that? Does it depend on the domain?

Say I have three unicellular organisms: a eukariote, a bacterium and an archaeon. If I cut off nutrition from them at the same time, how long will it take for them to die? What will their death look ...
5
votes
3answers
2k views

How did butterflies evolve to have eyes on their wings?

Some butterflies, such as the UK native Peacock butterfly (Google Image Search) have markings on their wings that look just like eyes, complete with a white fleck to imitate a convex, transparency ...
1
vote
1answer
57 views

What is the role of Homocysteine in cognitive function?

I'm looking at this link : Homocysteine and cognitive impairments and am looking for more information on specific cognitive impairments associated with elevated levels Homocysteine. That article is ...
1
vote
2answers
561 views

What is the most complex plant form?

At school we were told on scale of 0 through 1000 the animal kingdom ranges from amoeba the simplest/primitive being at 0, and Humans the most complex animals at 1000; what are the equivalent ...
7
votes
3answers
239 views

What alternatives are there to the amyloid hypothesis?

Given the recent failure of the Bapi clinical trial, there is a lot of questions that have arised from he amyloid hypothesis. However, I can't really think of many other mechanisms that don't involved ...
4
votes
1answer
159 views

Is there a way for a 19th century scientist to prove that the octopus doesn't revive?

Say a sophiscated scientist in the 19th century noted that applying soy sauce on a dead octopus leads to movement of the legs, as a result of the voltage differences resulting from the salt in the soy ...
13
votes
2answers
900 views

Is the EC50 of an activating protein for an enzyme a good indicator for the binding affinity Kd?

We work with a membrane protein system where measuring the affinity between the enzyme and the upstream activating protein has been difficult, and when measured in detergent solution, it is almost 100 ...
3
votes
0answers
109 views

RMSD during conformational transition in proteins

When I was investigating the differences between protein structures obtained by X-ray crystallography and NMR spectroscopy, I found the paper [1] compairing structures of several proteins resolved ...
2
votes
2answers
826 views

What are the most important differences between HSP70 and HSP90?

Question originally asked on Quora. These proteins have many functional similarities, so why do cells need both to handle unfolded proteins?
1
vote
0answers
68 views

When should endocytosis inhibitors be used in cell binding assays?

I'm beginning to do some cell-binding assays and I would like for my proteins to not be endocytosed by my mammalian cells. Typical suggestions are for the cells to be kept on ice and that the binding ...
2
votes
3answers
298 views

Where can I find a list of diseases and their incidence?

Say I am studying a particular disease and I know that its incidence is 0.8 per 100000 children below the age of 18, how would I find the incidence of a whole bunch of other pediatric diseases (or ...
8
votes
3answers
202 views

What would need to be discovered to prove there is extraterrestrial life?

Curiosity is on the Martian surface and is equipped with a slew of laboratory equipment. What would Curiosity need to discover to prove there is or has been life on Mars? Would it have to find DNA (or ...
5
votes
3answers
143 views

Do dogs have something different about their physiology that allows them to pant without hyperventilating?

I was wondering this as I considered how effective panting would be for humans as a means of cooling.

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