1
vote
1answer
67 views

Dimethyltryptamine and Sigma 1-type opioid receptor interaction

Where exactly do dimethyltryptamine and sigma 1-type opioid receptor interact? I read in this When the Endogenous Hallucinogenic Trace Amine N,N-Dimethyltryptamine Meets the Sigma-1 Receptor but it ...
-5
votes
1answer
207 views

How is it proved, that antediluvian people didn't live for hundreds of years? [closed]

Bible says that antediluvian people lived for 800-900 of years. Nowadays apologists say that it is possible and that we just can't know the truth. I know that one of the basic science principles is ...
3
votes
1answer
50 views

Where can I find a full genealogy of human cell types?

It is said on Wikipedia, that the precursor of blastocyst is a morula, and that the precursor of morula is a zygote. This gives us the part of genealogy tree of cell types. Unfortunately, no full ...
1
vote
2answers
45 views

Does a piezoelectric organic substance exist?

that contracts rapidly, in 10 seconds or less, by .5mm or more, when bombarded by electrons as from a cathode ray tube? or expands? could either be living tissue or dead organic matter. thanks!
1
vote
1answer
239 views

Why does beta-2-Thienylalanine inhibit bacterial growth?

I'm trying to obtain a better understanding of the Guthrie Test, which checks whether people have a disease called PKU. The Guthrie test uses bacteria to check for Phenylalanine (the amino acid) in ...
6
votes
1answer
290 views

Models of quorum sensing for multi-agent systems

Quorum sensing is a system of stimulus and responses correlated to population density that is used by bacteria to coordinate gene-expression. I am looking for a simple computational/mathematical model ...
9
votes
1answer
642 views

How many gigabytes of DNA are there on earth?

The human genome is about 770 MB, the C. elegans genome is about 100 MB, the yeast S. cerevisiae is about 12 MB. Different other genomes have been sequenced: how many GB of genomic DNA we have now? ...
1
vote
1answer
212 views

What is an on-line measurement? What is an off-line measurement?

See it used here: http://en.wikipedia.org/wiki/Fed-batch. In the table giving the different strategies to control growth in a fed-batch culture, one finds, for example: "on-line measurement of ...
2
votes
0answers
18 views

Are there any antigen electronic sensors? [closed]

Is it possible somehow to attach antibody to silicon or to other electronic component chemical, and have electronic detector of correspondent antigen? Does such devices exist?
3
votes
2answers
4k views

Does bright environment strain eyes more than dim?

I'm trying to figure out how to modify my working conditions so that I can program longer without harming my eyes. Because doing so experimentally hasn't given conclusive results so far, I decided to ...
2
votes
0answers
50 views

Removal of the Initial Methionine in Venus for FRET

I'm working on building some FRET reporters. In addition to a cleavage site (of varying composition from 15-18AA), a 1 AA linker, I'm using Venus and Cerulean. Initially I was worried that 18AA ...
2
votes
0answers
106 views

What causes a selective shift of colour perception after removing wavelength filtered glasses?

Background To improve sleep by reducing blue-light melatonin disruption, I wear night-glasses that filter short wavelengths (e.g. something like these). With these glasses on, both the top and bottom ...
0
votes
1answer
73 views

Does the eye image interval refresh? [closed]

It's known the human eye takes 24 images per second. But does this refresh? For example after sleeping. Or will it always be the same interval? I talk about when the eye takes the images. So it are ...
5
votes
2answers
456 views

Can this image be the result of a Western Blot?

I am currently researching image manipulation in the life sciences and stumbled upon a Western Blot looking very similar to the image below. For creating the image I have cut out the blot using the ...
11
votes
1answer
95k views

What causes random long white body hairs?

I'm sure many of you have experienced this - you scratch your back or brush your hand over your arm and find a ridiculously long thin white hair, sometimes as long as 3 or 4 inches. I know a few ...
3
votes
1answer
127 views

Attachment of muscles during molting in insects

Normally, insects' muscles are attached to their exoskeleton but what happens to this attachment when they are moulting? Sorry if this is an extremely silly question but I have wondered about it for ...
1
vote
1answer
155 views

Is there a human form of estrus?

Now I just learn that estrus is a trait in all mammals except Humans. So does it occur significantly in Humans? Of course I'm aware of the cliched "horny", "aroused" etc., but is it a biological ...
2
votes
1answer
422 views

What is the effect of flash pasteurisation on Maillard reactions or production of AGEs in milk?

Does flash UHTP homogenision and pasteurisation change significantly the extent of maillard reaction in milk compared with traditional batch pasteurisation? If this is significant does this effect the ...
1
vote
0answers
125 views

Why can't sodium butyrate be delivered orally in humans and other mammals?

I think I know why -- bioavailability problems but since I have no firm evidence to support this theory I thought I would ask the biology stackexchange community for their input. I'd like some firm ...
2
votes
1answer
75 views

Terminology question about the correct term for areas of biological research

I am writing a paper about DNA sequence prediction. DNA sequence prediction is done across various areas of biology, including, for example, RSS sequence prediction (in immunology) and prediction of ...
4
votes
2answers
517 views

Does bleach destroy RNAse activity, and if so, how does it do it?

I am working with RNA samples, and I'm trying to be very careful about RNAse contamination. I have some questions about bleach, though. Some people say that a solution of bleach is enough to destroy ...
11
votes
3answers
323 views

Most suitable biodiversity index

I am conducting an investigation into the effect of two different grass management techniques (grazing vs. machine-mowing) upon floral biodiversity. I have collected my data and now need to process ...
3
votes
0answers
38 views

Adenosine metabolism

Are adenosine or its catabolites increased in inflamed airways? How can I assess this? I am trying to use inhibitors for adenosine deaminase, xanthine oxidase, and purine nucleoside phosphorylase, but ...
6
votes
1answer
248 views

How does skin healing work?

I stacked my bike and split my head right open. About three weeks later the scab falls off and the skin is sealed over, like magic! How does it all work? How does the brain know that part of the ...
18
votes
3answers
1k views

How long can I store extracted RNA?

If I extract RNA from a (leaf tissue) sample using a one-step phenol:chloroform extraction, how long can those samples be stored at -80°C? And how many times can I defrost and refreeze them before ...
8
votes
2answers
97 views

Is there a Reverse Transcription optimization for long, 9kb, transcripts?

Has anyone optimized RT for long transcripts (9kb)? The downstream application will be PCR amplification and Illumina library prep. It will be trivial to make internal primers sets for the PCR that ...
3
votes
1answer
526 views

Is there an optimal composition and length for protein linkers in FRET?

I'm designing a protein that I'd like to use in FRET reporting. General idea on the shape is: FRETprotein1--Linker--CleavageSite--Linker--FRETprotein2. I would like to know what AA are best for the ...
8
votes
1answer
389 views

Is sexual reproduction outside the same biological family possible? Has it ever occured successfully?

Are there any examples of two species taxonomically classified in different biological families that have successfully hybridized and produced viable offspring? If not, is there an example of where ...
9
votes
1answer
762 views

Could humans and chimpanzees hybridize?

In some cases two species can hybridize. For example, Tigers and lions can hybridize to produce "Ligers". Would it also be possible for humans and chimpanzees (or any other species) to hybridize ? ...
3
votes
1answer
74 views

Historical recovery from mass extinction events

Is there a way to generally characterize how species "regrew" after the various mass extinction events happening periodically from 450 Ma to 65 Ma. Would the surviving species just start back where ...
4
votes
1answer
2k views

Difference between mutation and DNA damage

What is the strict difference between mutation and DNA damage? As far as I understand it, a mutation is an alteration in the genetic sequence, having "tricked" the repairing machinery and thus ...
6
votes
1answer
175 views

Does knowing the sex of each of a couple’s first N children have any marginal value in predicting the sex of child N+1?

Does knowing the sex of each of a couple’s first N children have any marginal value in predicting the sex of child N+1? By “marginal” I mean predictive power beyond other known effects, e.g., the race ...
2
votes
1answer
7k views

What are the differences between white and brown adipose tissue?

What are the differences between white and brown adipose tissue? Here are some that I have come across: ...
4
votes
1answer
180 views

Microarray data and analysis tools

Microarray has various uses, and to analyse the data a main function classification is used. There are many methods used to classify the data but what are the best and most frequently used methods? ...
4
votes
0answers
66 views

Does DHA increase the effects of clarithromycin?

I've read on this publication that every drug that induces CYP3A can reduce the effectiveness of clarithromycin. Clarithromycin inhibits CYP3A. But it does not say anything about the opposite ...
2
votes
1answer
226 views

How does electroporation mediated recombination work?

For yeast and other organisms, DNA can be readily taken up into the cell naturally or through membrane disruption. What does applying a voltage to cells do exactly that allows more recombination to ...
21
votes
2answers
771 views

How is temperature sensed?

Can anyone summarize the mechanism by which when an object of a given temperature is placed in contact with, say, the skin on a human fingertip, the average speed of the particles of the object is ...
1
vote
2answers
64 views

Protocol for measuring stamina of arthritic mice

I am going to make some mice ill with arthritis. The medicine which I am testing as control is known to cause extreme fatigue. I think I've improved it. I'd like to humanly measure their stamina in ...
2
votes
1answer
133 views

The concepts of relatedness - Hamilton's rule and kin selection

Here is a quotation from this wikipedia page The relatedness parameter (r) in Hamilton's rule was introduced in 1922 by Sewall Wright as a coefficient of relationship that gives the ...
4
votes
1answer
65 views

Who was the first to talk about evolvability?

"Evolvability is the capacity of a system for adaptive evolution." (source) There are several other definitions though: Who was the first person to use the word "evolvability"? Who was the first to ...
2
votes
1answer
949 views

Transfer of antibodies in breast milk of humans

Why isn't the IgA secreted in breast milk digested due to proteases of the digestive system in the baby? Wikipedia says: The secretory component of sIgA protects the immunoglobulin from being ...
1
vote
1answer
561 views

Transfer of antibodies from mother to fetus

My questions: When does fetus begins to acquire antibodies from mother? Does it continue throughout the pregnancy? From Wikipedia: http://en.wikipedia.org/wiki/Passive_immunity This occurs around ...
4
votes
2answers
847 views

Microscope recommendation for an amateur?

I am a mathematics student looking for a hobby and this has come up as a potential hobby. Thus I am interested in buying a high-magnification microscope that is within the limits of my budget. My ...
3
votes
3answers
426 views

Bioinformatics tool for “pairwise alignment” of complementary sequences?

I'm currently working on some ribozyme binding, and I'm looking for a tool that will essentially analyze the regions of the degree of complementarity in two sequences in order to extrapolate ...
8
votes
2answers
138 views

What is the effective relatedness of inbreeding?

If a human inbreeds with a relative, how distant does the relative have to be before the homozygosity in the child is no higher than if the mate were randomly chosen from the global population?
3
votes
0answers
59 views

Nocioception (pain perception) in subcutaneous tissue

There seem to be no nocioceptors (pain and temperature sensitive nerve endings) in subcutaneous fat. there are nocioceptors and other receptors in veins running through fat, but these can be avoided. ...
2
votes
1answer
63 views

How to refer to person-derived and place-derived species names

Are there words that categorize latin specific epithets by how they're derived? Specifically, I was wondering if there exist adjectives to refer to: Person-derived species names as in Nothura darwini ...
2
votes
3answers
211 views

Mechanical cause of loss of consciousness

Consciousness is an electrical and chemical interaction in the brain, caused by neurons firing and chemical interactions. How does a mechanical "force" cause this to stop working? i.e. How does a ...
5
votes
1answer
506 views

What do the signs +/+ +/- mean in this image?

I don't understand what this graph is supposed to explain, especially what the signs +/+ or -/- mean. I just know it characterises some rats.
3
votes
1answer
70 views

What makes drosophila eyes red? and is it stable?

I have Drosophila melanogaster which I am doing an eye pigmentation assay on in the future. To do this I will dissolve the heads, 10 of them removed from frozen whole flies, in acidified ethanol for ...

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