4
votes
3answers
197 views

Phospholipid Bilayer structural reversal

What would happen if the phospholipids in the phospholipid bi-layer were reversed, the fatty acid tails now facing outwards and the phosphate heads facing inwards? I'm assuming this will not affect ...
1
vote
1answer
72 views

reason for “not for diagnostic use” advice in protocols

I read "not for diagnostic use" in every protocol i saw. why is it so? which differences have the kits and material that are used for diagnostic purposes?
3
votes
4answers
320 views

Is there a downloadable list of all species along with their traditional classification?

I'm looking for a downloadable list of all known (or better said, online documented) species in this straightforward format, as an example the European Frog: Kingdom: Animalia Division: Chordata ...
2
votes
1answer
115 views

Can pets catch the cold?

Last night I was drying my cat with a towel after shenanigans in the rain and she sneezed! Questions Can cats/dogs/hamsters or other pets catch the cold? How quickly do they recover?
1
vote
2answers
211 views

How likely is it that Earth has millions of different species?

I know that the probability of life existing on a habitable planet is pretty slim. But, how likely is it that it hapenned millions of times in the same planet? Or was it only a few species that ...
7
votes
1answer
114 views

The mechanism of mechanoreception?

I am interested in knowing the molecular mechanism behind mechanoreception/mechanotransduction (i.e. mechanism behind receptor potential generation on mechanical stimulation). I know that most ...
3
votes
1answer
104 views

Is there a molecular basis to intelligence?

Is there any explanation, gene(s) or whatever detected, that are co-related or explicitly related via mechanical bio-molecular (or at any other level) models that explain the higher or lower ...
4
votes
2answers
401 views

Ethidium bromide and mutagenesis on cloning

When performing a DNA cloning, sometimes PCR amplicon is run in agarose and it is detected by ethidium bromide marking under UV light. After that, gel is sliced, DNA extracted from gel....... until ...
6
votes
2answers
143 views

How much DNA of mitochondrial origin is incorporated in main cell's DNA?

And especially three points : in which chromosomes is it located (especially for the human case) ? how do we know about it ? does the proportion and composition vary a lot from one eukaryot to ...
3
votes
0answers
54 views

Database of Medical Assertions

Can anyone point me toward a computationally-accessible database of medical assertions? I'm looking for something where each row in the database contains a single unit of knowledge. It could either be ...
7
votes
1answer
230 views

How is color information transmitted from the eye to the brain?

Is color information sent from the eye to the brain frequency-modulated, or are different colors transmitted by different axons? I know that each ganglion cell is connected to multiple photoreceptors....
2
votes
1answer
102 views

How many different smells can a human recognize?

How many different smells can a human recognize? If the space of smells is not discrete, how many dimensions it has (for example, the space of colors is three-dimensional).
2
votes
1answer
1k views

DNA degradation rate

Usually DNA sample manipulation is realized with an ice box at hand in order to avoid degradation, and also its storage is set at -20ºC. Nevertheless, DNA has been obtained from really ancient samples ...
0
votes
1answer
77 views

Looking for raw cell videos from a light microscope

First off, I'm not looking for online lectures. I am trying to find creative commons licensed videos of live cells moving around without annotation or anything extra. I would prefer a few minutes of ...
1
vote
2answers
174 views

what does sequences overlap indicate

what does it mean if different protein sequences overlap upon multiple alignment, are they the same, do they have a common ancestor, are they recombinants of each other and how does one go on to ...
1
vote
1answer
251 views

List of all reported bacteria

I would like to know were to download a table file with all reported bacteria and its corresponding PHYLUM, CLASS, ORDER and FAMILY. Basically, its the same table than this one from GOLD genomes but ...
4
votes
1answer
62 views

Erythroblastosis Foetalis

If Rh- mother has Rh+ baby, the mother can become sensitized during first pregnancy and then if subsequent fetuses are also Rh+, there can be eryhtroblastosis foetalis. I read that if mother is O- ...
0
votes
1answer
72 views

bioinformatics /genomics [closed]

i am looking for likely truncation sites to prove recombination in sequences. i have 4 sequences. i believe one to be the "real sequence" and the other 3 to be recombinants caused by cleavage possibly ...
1
vote
1answer
96 views

Death because of no radio waves [closed]

I read somewhere that a man dies if he is isolated from natural electromagnetic fields and waves. (I imply fields of radio frequencies and below.) Is it true?
4
votes
4answers
215 views

Electronic laboratory notebook (ELN)

I have been using old style lab book for some time now but with increasing work on computer and storing sequencing results and gel pictures on computer it would be nice to have everything on computer ...
3
votes
1answer
40 views

Manufacturing toxoids

Toxoids produced by tetanus and diphtheria bacteria are detoxified with formaldehyde, yet their antigen properties remain. Source : Biological Science by Taylor What does formaldehyde do ?
3
votes
3answers
46 views

Immune reaction to “new” protein

I read in Bruce Alberts Molecular Biology of the cell : Normal mice,for example, cannot make an immune response against one of their own protein components of the complement system called C5. ...
3
votes
1answer
96 views

Thymus and maternal microchimerism

I read in Bruce Alberts Molecular Biology of The Cell : ....If,however,cells from one strain of mouse are introduced into a neonatal mouse of another strain , some of these cells survive for most ...
4
votes
3answers
1k views

Antigenic and non antigenic

Can any foreign molecule be non- antigenic ? Can any foreign peptide be non-antigenic ? What is the difference between an antigenic and a non-antigenic peptide ?
2
votes
2answers
102 views

How are T cells transported?

T cells are formed in bone marrow and mature in Thymus. How are they transported from bone marrow to thymus ? Through the lymph vessels ?
6
votes
1answer
3k views

Why don't we have hair on palms?

We have hair all over the body except palms. What is the biological reason behind this? Thanks
5
votes
2answers
145 views

The least complex animals with ability to dream

People can dream, dogs can dream, cats probably too when they are sleeping. What about other creatures? Can a bird dream? Do rats have dreams? Are there any studies about that kind of thing? What ...
3
votes
2answers
326 views

Which restriction enzyme would i use?

Plasmid pBr322 includes two genes that confer antibiotic resistance: a gene for ampicillin and a gene for tetracycline. The cutting site for the restriction enzyme BamH1 is in the middle pf the ...
7
votes
1answer
171 views

How much does a biological experiment to validate a gene function cost?

I am computer scientist working on machine learning methods applied to predicting missing Gene Ontology annotations. In many papers, I wrote that my computational methods are very useful to suggest ...
6
votes
2answers
4k views

How is membrane capacitance related to the increased speed of saltatory conduction?

Here is the original question which inspired my question. As explained by the answers there, the reason saltatory conduction in myelinated neurons is faster than non-myelinated conduction is because ...
4
votes
1answer
76 views

What is the best way to orally administer a water insoluble powdered drug to macaque monkeys?

They typically need to be given ~150mg, once a day, and it'll last for two weeks. The drug is very water insoluble, becomes almost like a paste, not suitable for tube feeding. And yes, this is for for ...
3
votes
4answers
1k views

How come most animals never seem to evolve over millenia?

People often say, including those with extensive knowledge in biology, that a certain species of animal will evolve in one way or another: 1.From changing environments. 2.Mutations. 3.Possibly even ...
2
votes
1answer
392 views

Why is cyanide poisonous?

I know cyanide inhibits complex IV in the electron transport chain, but I don't understand why this makes it so toxic. If cyanide is bound to the complex, can't the electrons just bypass it and ...
3
votes
3answers
127 views

Can humans be printed?

Is it possible to spray stem cells on fully grown skeleton to get fully grown humans? Currently, just read about recent advances, and wondered if something like this is possible.
4
votes
1answer
3k views

Identification - What kind of animal leaves these tracks?

I live in the suburbs of Washington DC where it recently snowed. I was admiring all of the tracks left behind by wildlife of all kinds when I came across these prints, that I was unable to recognize ...
2
votes
1answer
1k views

What are the visual, behavioral similarities and differences between Yellow Fever Mosquito (Aedes aegypti) and the Tiger Mosquito (Aedes albopictus)?

The Tiger and Yellow Fever Mosquito visually look very similar. Recognizing the difference is important for tracking and controlling the spread of Yellow Fever, Dengue fever and other diseases. ...
2
votes
2answers
852 views

Are there genetic similarity between humans and pigs that don't exist in chimps?

Chimps are our closer relative. Any genetic similarity between humans and chimps must exist on the common ancestor. Pig branch out sooner. So, any genetic similarity between humans and pigs must be ...
1
vote
2answers
279 views

Is there any genetic similarity that defy evolution theory?

For example, say species A is common ancestor of B, and C. Species B is a common ancestor of D and E. We would expect that there will be more genetic similarity between D and E than D and C. And ...
3
votes
1answer
153 views

When might an inhibitor of bacterial transformation be useful?

I am part of a project elucidating some structures that are required for bacterial transformation. We have the opportunity to screen inhibitors of the system to stop it from functioning. I am not a ...
2
votes
1answer
71 views

Mutation in pre-mRNA sequence

Has there any mutations been recorded which cause harmful effects due to change in the part of pre-mRNA responsible for proper m-RNA splicing ?
2
votes
2answers
732 views

Histidine - why essential for children?

Why is histidine an essential amino acid for children but not for adults ? What changes in the body occur which lead to the formation of histidine in adults but not in children ? What causes these ...
2
votes
3answers
70 views

Anti-antibodies for preventing transplant rejection

Transplanted organs from the donor are attacked by antibodies from the recepient. So can't we construct anti-antibodies and destroy specifically those antibodies which are causing the rejections ? (...
4
votes
4answers
457 views

Is there a PSI-BLAST for nucleotide sequences?

I understand that one can translate a nucleotide sequence and run PSI-BLAST on the protein (proteins if you take the 6 reading frames), but I'm looking for distant homology for bacterial small RNAs (...
1
vote
0answers
81 views

What is the cause of singularity in phase response curve of human sleep and bright light?

I have no background in science as I am a computer programmer, but I am trying to get information on phase response curves, human sleep and exposure to bright light as I am trying to get to grips with ...
4
votes
1answer
147 views

pfu Turbo DNA polymerase AD

What is the duration (Life") of pfu turbo DNA polymerase AD. I am trying o Amplification a 3.3kb fragment and the PCR schedule is 6 hours long. The manufacturers notes just specify that its activity ...
5
votes
1answer
156 views

How can this bird be identified? Can someone please identify this bird?

These photographs have been taken in Warora, India. Could someone please help identify this bird?
4
votes
1answer
76 views

What evidence is there on the medical effects of circumcision?

If this is the wrong place to post this question, then I will delete it and post it were it belongs. I have heard many conflicting things about circumcision. I have heard that it reduces the rate of ...
12
votes
2answers
2k views

Why is there more variation in proteins than genes?

The Genome of a cell or organism is the same as that of the entire organism. However, the proteome of an organism is much greater than that of each cell (unless the organism is unicellular). How do ...
8
votes
4answers
160 views

Organisms as potential Bio-Weapons?

Question: Given that with genetic engineering we can customize organisms as bio-weapons. Which species have the most worrying potential to be weaponized for mass destruction? Background: ...
0
votes
1answer
74 views

How do transplanted stem cells find their way to bone marrow?

Miraculously, transplanted stem cells find their way to the bone marrow missing the stem cells. How do they achieve this?

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